ABIN358538

antibody from antibodies-online

Targeting: MAP2K1 MAPKK1, MEK1, PRKMK1

No application information provided.

Antibody Data

Product number

ABIN358538

Provider

antibodies-online

Product name

anti-Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (pSer222) antibody

Antibody type

Polyclonal

Description

Protein A column, followed by two-step phosphospecific peptide affinity purification

Reactivity

Human

Host

Rabbit

Epitope

pSer222

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress.

Naegele S, Morley SJ
The Journal of biological chemistry 2004 Oct 29;279(44):46023-34

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MEK1 and MEK2, different regulators of the G1/S transition.

Ussar S, Voss T
The Journal of biological chemistry 2004 Oct 15;279(42):43861-9

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Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

Ohren JF, Chen H, Pavlovsky A, Whitehead C, Zhang E, Kuffa P, Yan C, McConnell P, Spessard C, Banotai C, Mueller WT, Delaney A, Omer C, Sebolt-Leopold J, Dudley DT, Leung IK, Flamme C, Warmus J, Kaufman M, Barrett S, Tecle H, Hasemann CA
Nature structural & molecular biology 2004 Dec;11(12):1192-7

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Large-scale characterization of HeLa cell nuclear phosphoproteins.

Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5