ABIN966559

antibody from antibodies-online

Targeting: MAP2K1 MAPKK1, MEK1, PRKMK1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966559

Provider

antibodies-online

Product name

anti-Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (pSer217) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human MEK1 around the phosphorylation site of serine 217 (I-D-SP-M-A).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer217

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling.

Preisinger C, Körner R, Wind M, Lehmann WD, Kopajtich R, Barr FA
The EMBO journal 2005 Feb 23;24(4):753-65

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Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72.

Yaglom J, O'Callaghan-Sunol C, Gabai V, Sherman MY
Molecular and cellular biology 2003 Jun;23(11):3813-24

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Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in T84 cells.

Dahan S, Busuttil V, Imbert V, Peyron JF, Rampal P, Czerucka D
Infection and immunity 2002 May;70(5):2304-10

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Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

Shen R, Ouyang YB, Qu CK, Alonso A, Sperzel L, Mustelin T, Kaplan MH, Feng GS
Molecular and cellular biology 2002 May;22(10):3230-6

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Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts.

Laine P, Reunanen N, Ravanti L, Foschi M, Santra M, Iozzo RV, Kähäri VM
The Biochemical journal 2000 Jul 1;349(Pt 1):19-25