Explore
Validate
Learn
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN966563 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized non-phosphopeptide derived from human MEK1 around the phosphorylation site of serine 221 (A-N-SP-F-V).
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.
Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1.
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells.
Zebisch A, Staber PB, Delavar A, Bodner C, Hiden K, Fischereder K, Janakiraman M, Linkesch W, Auner HW, Emberger W, Windpassinger C, Schimek MG, Hoefler G, Troppmair J, Sill H
Cancer research 2006 Apr 1;66(7):3401-8
Cancer research 2006 Apr 1;66(7):3401-8
Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity.
Luciano BS, Hsu S, Channavajhala PL, Lin LL, Cuozzo JW
The Journal of biological chemistry 2004 Dec 10;279(50):52117-23
The Journal of biological chemistry 2004 Dec 10;279(50):52117-23
Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1.
Gopalbhai K, Jansen G, Beauregard G, Whiteway M, Dumas F, Wu C, Meloche S
The Journal of biological chemistry 2003 Mar 7;278(10):8118-25
The Journal of biological chemistry 2003 Mar 7;278(10):8118-25
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells.
Wang X, Jin DY, Wong HL, Feng H, Wong YC, Tsao SW
Oncogene 2003 Jan 9;22(1):109-16
Oncogene 2003 Jan 9;22(1):109-16
No comments: Submit comment
No validations: Submit validation data