PAB18198
antibody from Abnova Corporation
Targeting: RPS6KB1
p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- PAB18198 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18198, RRID:AB_10713039
- Product name
- RPS6KB1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells.
Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K.
Briaud I, Lingohr MK, Dickson LM, Wrede CE, Rhodes CJ
Diabetes 2003 Apr;52(4):974-83
Diabetes 2003 Apr;52(4):974-83
Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
Huang C, Li J, Ke Q, Leonard SS, Jiang BH, Zhong XS, Costa M, Castranova V, Shi X
Cancer research 2002 Oct 15;62(20):5689-97
Cancer research 2002 Oct 15;62(20):5689-97
The activated glucocorticoid receptor modulates presumptive autoregulation of ribosomal protein S6 protein kinase, p70 S6K.
Shah OJ, Iniguez-Lluhi JA, Romanelli A, Kimball SR, Jefferson LS
The Journal of biological chemistry 2002 Jan 25;277(4):2525-33
The Journal of biological chemistry 2002 Jan 25;277(4):2525-33
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 293 cells, treated with serum (20 %, 15 mins), using RPS6KB1 polyclonal antibody (Cat # PAB18198).Peptide "+" means "peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of NIH/3T3 cells, using RPS6KB1 polyclonal antibody (Cat # PAB18198).Peptide "+" means "peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RPS6KB1 polyclonal antibody (Cat # PAB18198).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)