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LearnPAB18497
antibody from Abnova Corporation
Targeting: RPS6KB1
p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- PAB18497 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18497, RRID:AB_10714893
- Product name
- RPS6KB1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR.
The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.
Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta.
Granulocyte-macrophage colony-stimulating factor is a chemoattractant cytokine for human neutrophils: involvement of the ribosomal p70 S6 kinase signaling pathway.
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.
Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.
Lehman N, Ledford B, Di Fulvio M, Frondorf K, McPhail LC, Gomez-Cambronero J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Apr;21(4):1075-87
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Apr;21(4):1075-87
The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.
Shah YM, Rowan BG
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):732-48
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):732-48
Reoxygenation after severe hypoxia induces cardiomyocyte hypertrophy in vitro: activation of CREB downstream of GSK3beta.
El Jamali A, Freund C, Rechner C, Scheidereit C, Dietz R, Bergmann MW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Jul;18(10):1096-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004 Jul;18(10):1096-8
Granulocyte-macrophage colony-stimulating factor is a chemoattractant cytokine for human neutrophils: involvement of the ribosomal p70 S6 kinase signaling pathway.
Gomez-Cambronero J, Horn J, Paul CC, Baumann MA
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 15;171(12):6846-55
Journal of immunology (Baltimore, Md. : 1950) 2003 Dec 15;171(12):6846-55
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H
The Journal of biological chemistry 2001 Mar 30;276(13):9817-24
The Journal of biological chemistry 2001 Mar 30;276(13):9817-24
Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.
Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ
Cancer research 2001 Aug 15;61(16):5985-91
Cancer research 2001 Aug 15;61(16):5985-91
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RPS6KB1 polyclonal antibody (Cat # PAB18497).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
