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LearnABIN358318
antibody from antibodies-online
Targeting: RPS6KB1
p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN358318 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pSer418) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pSer418
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers.
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
Ribosomal p70S6K basal activity increases upon induction of differentiation of myelomonocytic leukemic cell lines HL60, AML14 and MPD.
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.
Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues.
Adem C, Soderberg CL, Hafner K, Reynolds C, Slezak JM, Sinclair CS, Sellers TA, Schaid DJ, Couch F, Hartmann LC, Jenkins RB
Genes, chromosomes & cancer 2004 Sep;41(1):1-11
Genes, chromosomes & cancer 2004 Sep;41(1):1-11
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S
Genome research 2004 Sep;14(9):1711-8
Genome research 2004 Sep;14(9):1711-8
Ribosomal p70S6K basal activity increases upon induction of differentiation of myelomonocytic leukemic cell lines HL60, AML14 and MPD.
Gomez-Cambronero J, Frye T, Baumann M
Leukemia research 2004 Jul;28(7):755-62
Leukemia research 2004 Jul;28(7):755-62
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.
Raught B, Peiretti F, Gingras AC, Livingstone M, Shahbazian D, Mayeur GL, Polakiewicz RD, Sonenberg N, Hershey JW
The EMBO journal 2004 Apr 21;23(8):1761-9
The EMBO journal 2004 Apr 21;23(8):1761-9
Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues.
Miyakawa M, Tsushima T, Murakami H, Wakai K, Isozaki O, Takano K
Endocrine journal 2003 Feb;50(1):77-83
Endocrine journal 2003 Feb;50(1):77-83
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