ABIN197035

antibody from antibodies-online

Targeting: RPS6KB1 p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197035

Provider

antibodies-online

Product name

anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pSer411) antibody

Antibody type

Polyclonal

Description

Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer411

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.

Krause U, Bertrand L, Hue L
European journal of biochemistry 2002 Aug;269(15):3751-9

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Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.

Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, Inagami T
The Journal of biological chemistry 1999 Dec 24;274(52):36843-51

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Cdc2-cyclin B phosphorylates p70 S6 kinase on Ser411 at mitosis.

Papst PJ, Sugiyama H, Nagasawa M, Lucas JJ, Maller JL, Terada N
The Journal of biological chemistry 1998 Jun 12;273(24):15077-84