abx015981

antibody from Abbexa

Targeting: RPS6KB1 p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx015981

Provider

Abbexa

Product name

Ribosomal Protein S6 Kinase Beta 1 (RPS6KB1) Antibody

Antibody type

Monoclonal

Description

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases.This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein.The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation.Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines.Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.