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LearnNB600-1049
antibody from Novus Biologicals
Targeting: RPS6KB1
p70(S6K)-alpha, PS6K, S6K, S6K1, STK14A
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB600-1049 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1049, RRID:AB_10002153
- Product name
- Rabbit Polyclonal p70 S6 Kinase/S6K Antibody
- Antibody type
- Polyclonal
- Description
- Affinity purified. This detects p70 S6 Kinase only when phosphorylated at Thr389.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 0.5 mg/ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model.
O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells.
Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death.
Zhang Q, Wei D, Tan M, Li H, Morgan MA, Sun Y
Neoplasia (New York, N.Y.) 2020 Apr 24;22(6):242-252
Neoplasia (New York, N.Y.) 2020 Apr 24;22(6):242-252
O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells.
Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, Lim JR, Kim SY, Lee JE, Park MC, Yoon JH, Choi MJ, Kim KS, Han HJ
Cell death & disease 2019 Aug 5;10(8):590
Cell death & disease 2019 Aug 5;10(8):590
Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death.
Lee KH, Lee SJ, Lee HJ, Choi GE, Jung YH, Kim DI, Gabr AA, Ryu JM, Han HJ
Frontiers in molecular neuroscience 2017;10:229
Frontiers in molecular neuroscience 2017;10:229
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: p70 S6 Kinase/S6K [p Ser389] Antibody [NB600-1049] - Analysis of phospho-p70 S6 Kinase in human breast cancer cell lines (MDA-MB-231 and MDA-MB-435) using anti-p70 S6 Kinase [p Thr389] antibody. Image from verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: p70 S6 Kinase/S6K [p Thr389] Antibody [NB600-1049] - Analysis of p70 S6 Kinase phosphorylation expression in Insulin treated Jurkat whole cell lysates. The lane on the left is treated with the antigen-specific peptide.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: p70 S6 Kinase/S6K [p Ser389] Antibody [NB600-1049] - p70 S6 Kinase/S6K [p Thr389] Antibody [NB600-1049] - Analysis of Phospho-p70 S6 Kinase in 293 cells.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: p70 S6 Kinase/S6K [p Thr389] Antibody [NB600-1049] - Human liver cancer tissue sections
