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- Antibody Data
- Antigen structure
- References [11]
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- Product number
- 22999-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PARP1 antibody
- Antibody type
- Polyclonal
- Description
- PARP1 antibody (Cat. #22999-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TNFRSF10B, a Therapeutic Target for Oral Squamous Cell Carcinoma Through Integrated Bioinformatics and Preliminary Experiments.
Acetaldehyde dehydrogenase 1A1 upregulation drives dacomitinib-induced skin toxicity through mitochondrial dysfunction and keratinocyte apoptosis.
Integrated analysis of Corylin from Psoralea Corylifolia inhibiting osteoporosis via MAPK pathway.
Retinal Protective Effect of Mono-Ethyl Fumarate in Experimental Age-Related Macular Degeneration via Anti-Oxidative and Anti-Apoptotic Alterations.
Tetrandrine downregulates TRPV2 expression to ameliorate myocardial ischemia/reperfusion injury in rats via regulation of cardiomyocyte apoptosis, calcium homeostasis and mitochondrial function.
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair.
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Yang Y, Zhuang Z, Hu Y, Liu J, Guo J, Jin L, Qiu Y
Technology in cancer research & treatment 2026 Jan-Dec;25:15330338261426318
Technology in cancer research & treatment 2026 Jan-Dec;25:15330338261426318
Acetaldehyde dehydrogenase 1A1 upregulation drives dacomitinib-induced skin toxicity through mitochondrial dysfunction and keratinocyte apoptosis.
Zhou W, Ma X, Tan L, Mei Y, Li H, Chen X, Yang D, Xu G, Yang Y, Wang J, Fang L
Cellular signalling 2025 Oct;134:111913
Cellular signalling 2025 Oct;134:111913
Integrated analysis of Corylin from Psoralea Corylifolia inhibiting osteoporosis via MAPK pathway.
Liu N, Yang Z, Yanzhang R, Shen R, Yi W, Teng J
Scientific reports 2025 Nov 19;15(1):40724
Scientific reports 2025 Nov 19;15(1):40724
Retinal Protective Effect of Mono-Ethyl Fumarate in Experimental Age-Related Macular Degeneration via Anti-Oxidative and Anti-Apoptotic Alterations.
Lee H, Zhang S, Ahn HR, Kim T, Kim J, Lee H, Jung SH, Kim J
International journal of molecular sciences 2025 Feb 7;26(4)
International journal of molecular sciences 2025 Feb 7;26(4)
Tetrandrine downregulates TRPV2 expression to ameliorate myocardial ischemia/reperfusion injury in rats via regulation of cardiomyocyte apoptosis, calcium homeostasis and mitochondrial function.
Jiang L, Zhou X, Zhao X, Wang Z, Huang A, Huang Y, Sun H, Guan F, Jiang W
European journal of pharmacology 2024 Feb 5;964:176246
European journal of pharmacology 2024 Feb 5;964:176246
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
Zhang Z, Li X, Guo J, He B, Wu L, Yang R, Li X, Fang D, Yang X, Yang D, Wang F, Tang M, Han Y, Jose PA, Wang H, Zeng C
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):164
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):164
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.
Yang M, Wang C, Zhou M, Bao L, Wang Y, Kumar A, Xing C, Luo W, Wang Y
Nucleic acids research 2022 Jun 24;50(11):6313-6331
Nucleic acids research 2022 Jun 24;50(11):6313-6331
MiR-362-5p, Which Is Regulated by Long Non-Coding RNA MBNL1-AS1, Promotes the Cell Proliferation and Tumor Growth of Bladder Cancer by Targeting QKI.
Wei X, Wang B, Wang Q, Yang X, Yang Y, Fang Z, Yi C, Shi L, Fan X, Tao J, Guo Y, Song D
Frontiers in pharmacology 2020;11:164
Frontiers in pharmacology 2020;11:164
Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair.
Quiñones JL, Thapar U, Wilson SH, Ramsden DA, Demple B
DNA repair 2020 Mar;87:102773
DNA repair 2020 Mar;87:102773
Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin.
Zou Y, Qiu G, Jiang L, Cai Z, Sun W, Hu H, Lu C, Jin W, Hu G
Oncotarget 2017 Aug 29;8(35):58231-58246
Oncotarget 2017 Aug 29;8(35):58231-58246
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PARP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PARP1. This antibody recognizes human, mouse antigen. The PARP1 antibody has been validated for the following applications: ELISA, WB analysis.
