ABIN362227

antibody from antibodies-online

Targeting: PXN

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362227

Provider

antibodies-online

Product name

anti-Paxillin (PXN) (pTyr31) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pTyr31 (T-P-Y (p) -S-Y) derived from Human Paxillin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pTyr31

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.

Huang Z, Yan DP, Ge BX
Cellular signalling 2008 Nov;20(11):2002-12

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PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates.

Davidson D, Veillette A
The EMBO journal 2001 Jul 2;20(13):3414-26

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Actin-based motility of intracellular microbial pathogens.

Goldberg MB
Microbiology and molecular biology reviews : MMBR 2001 Dec;65(4):595-626, table of contents

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Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells.

Kook S, Shim SR, Choi SJ, Ahnn J, Kim JI, Eom SH, Jung YK, Paik SG, Song WK
Molecular biology of the cell 2000 Mar;11(3):929-39

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Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase.

Fleming I, Bauersachs J, Schäfer A, Scholz D, Aldershvile J, Busse R
Proceedings of the National Academy of Sciences of the United States of America 1999 Feb 2;96(3):1123-8