BS3653

antibody from Bioworld Technology, Inc
Targeting: EIF2AK2 EIF2AK1, PKR, PPP1R83, PRKR
Provider product page for BS3653
Western blot
Immunohistochemistry

Antibody data

Product number
BS3653 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3653, RRID:AB_1663201
Product name
PKR (K440) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 410-460 of Human PKR.
Description
An interferon-inducible, RNA-dependent protein serine/threonine kinase (PKR) has been described. PKR in earlier literature is variously known as DAI, dsJ, PI kinase, p65, p67 or TIK for the mouse kinase; and p68 or p69 for the human kinase. The PKR kinase substrate is the Ï« subunit of protein synthesis initiation factor eIF-2. Phosphorylation of eIF-2Ï« on serine-51 results in inhibition of translation. Molecular cDNA clones have been isolated from both human and mouse cells. The serine/threonine kinase catalytic domains map to the carboxy terminal half of the protein while the RNA-binding domains are located in the amino terminal region. Three kinds of regulation of PKR enzymatic activity have been described.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF2AK2 protein structure - BS3653 shown in red.