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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500507 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- PKR antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human PKR.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action.
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.
Gil J, García MA, Esteban M
FEBS letters 2002 Oct 9;529(2-3):249-55
FEBS letters 2002 Oct 9;529(2-3):249-55
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.
Saelens X, Kalai M, Vandenabeele P
The Journal of biological chemistry 2001 Nov 9;276(45):41620-8
The Journal of biological chemistry 2001 Nov 9;276(45):41620-8
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action.
Gil J, Esteban M
Apoptosis : an international journal on programmed cell death 2000 Apr;5(2):107-14
Apoptosis : an international journal on programmed cell death 2000 Apr;5(2):107-14
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.
Meurs E, Chong K, Galabru J, Thomas NS, Kerr IM, Williams BR, Hovanessian AG
Cell 1990 Jul 27;62(2):379-90
Cell 1990 Jul 27;62(2):379-90
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PKR in Caco-2 whole cell lysate with AP30676PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of PKR in rat lung tissue with AP30676PU-N at 5 ?g/ml.
