Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1003006 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- PKR antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human PKR.
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action.
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.
Gil J, GarcĂa MA, Esteban M
FEBS letters 2002 Oct 9;529(2-3):249-55
FEBS letters 2002 Oct 9;529(2-3):249-55
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation.
Saelens X, Kalai M, Vandenabeele P
The Journal of biological chemistry 2001 Nov 9;276(45):41620-8
The Journal of biological chemistry 2001 Nov 9;276(45):41620-8
Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action.
Gil J, Esteban M
Apoptosis : an international journal on programmed cell death 2000 Apr;5(2):107-14
Apoptosis : an international journal on programmed cell death 2000 Apr;5(2):107-14
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.
Meurs E, Chong K, Galabru J, Thomas NS, Kerr IM, Williams BR, Hovanessian AG
Cell 1990 Jul 27;62(2):379-90
Cell 1990 Jul 27;62(2):379-90
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