DPABH-18392

antibody from Creative Diagnostics

Targeting: PLEC EBS1, PCN, PLEC1, PLTN

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-18392

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-18392, RRID:AB_2514685

Product name

Rabbit Anti-Human PLEC Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Concentration

Lot specific

Storage

2 - 8° C. 1 year from date of receipt