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- References [14]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17592-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17592-1-AP, RRID:AB_10644483
- Product name
- PYK2 antibody
- Antibody type
- Polyclonal
- Description
- PYK2 antibody (Cat. #17592-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protocadherin γC4 regulates neuronal survival and dendritic self-avoidance.
Dual Single-Atom Engineered NADH Oxidase-Mimic Boosts In Situ NAD(+) Biotransformation for Targeted Myocardial Ischemia/Reperfusion Protection.
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
Macrophage DGKζ-mediated phosphatidic acid remodeling aggravates acute liver failure.
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2.
Endothelial cell Ass1 inhibits arteriosclerotic calcification in diabetes mellitus.
Mettl3/Ythdf2 regulate macrophage inflammation and ROS generation by controlling Pyk2 mRNA stability.
A Novel Splicing Mutation c.335-1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2.
ADP/P2Y(1) aggravates inflammatory bowel disease through ERK5-mediated NLRP3 inflammasome activation.
Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia.
Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice.
Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.
Higuchi R, Tatara M, Horino S, Katori S, Sanbo M, Hirabayashi M, Watanabe M, Konno A, Hirai H, Yoshioka Y, Hirabayashi T, Kobayashi T, Kaneko R, Yagi T
Communications biology 2026 Mar 7;9(1)
Communications biology 2026 Mar 7;9(1)
Dual Single-Atom Engineered NADH Oxidase-Mimic Boosts In Situ NAD(+) Biotransformation for Targeted Myocardial Ischemia/Reperfusion Protection.
Liu J, Guo X, Wang N, Zhang X, Wang X, Li G, Hou X, Yu L, Chen Y, Li R
Advanced materials (Deerfield Beach, Fla.) 2026 Apr 21;:e19122
Advanced materials (Deerfield Beach, Fla.) 2026 Apr 21;:e19122
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.
Zhou H, Zhang Z, Liu Z, Xiong L, Ran X, Liu J, Ran Y, Wen Y, Chen W, Xu J
Molecular biomedicine 2025 Oct 30;6(1):91
Molecular biomedicine 2025 Oct 30;6(1):91
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
Gao X, Fan X, Yu X, Wang R, Zhang B, Li Y, Liu X, Yang Y
Journal of pediatric urology 2025 Aug;21(4):834-843
Journal of pediatric urology 2025 Aug;21(4):834-843
Macrophage DGKζ-mediated phosphatidic acid remodeling aggravates acute liver failure.
Miao Y, Lin T, Wang B, Xu J, Li C, Li Z, Zhang X, Zhou C, Aji T, Tan M, Aisa HA, Li J
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4078-4095
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4078-4095
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Liu L, Liu L, Yue C, Du S, Liu J, Yu Z
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2.
Liao Y, Remsing Rix LL, Li X, Fang B, Izumi V, Welsh EA, Monastyrskyi A, Haura EB, Koomen JM, Doebele RC, Rix U
Cell chemical biology 2024 Feb 15;31(2):284-297.e10
Cell chemical biology 2024 Feb 15;31(2):284-297.e10
Endothelial cell Ass1 inhibits arteriosclerotic calcification in diabetes mellitus.
Jiang H, Zhou Y, Zhang L, Yu W, Li L, Dai Z, Zhao L, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117739
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117739
Mettl3/Ythdf2 regulate macrophage inflammation and ROS generation by controlling Pyk2 mRNA stability.
Cai Y, Yu R, Zhang Z, Li D, Yi B, Feng Z, Xu Q
Immunology letters 2023 Dec;264:64-73
Immunology letters 2023 Dec;264:64-73
A Novel Splicing Mutation c.335-1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2.
Jia L, Limeng D, Xiaoyin T, Junwen W, Xintong Z, Gang X, Yun B, Hong G
Stem cell reviews and reports 2022 Dec;18(8):2646-2661
Stem cell reviews and reports 2022 Dec;18(8):2646-2661
ADP/P2Y(1) aggravates inflammatory bowel disease through ERK5-mediated NLRP3 inflammasome activation.
Zhang C, Qin J, Zhang S, Zhang N, Tan B, Siwko S, Zhang Y, Wang Q, Chen J, Qian M, Liu M, Du B
Mucosal immunology 2020 Nov;13(6):931-945
Mucosal immunology 2020 Nov;13(6):931-945
Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia.
Barad M, Csukasi F, Bosakova M, Martin JH, Zhang W, Paige Taylor S, Lachman RS, Zieba J, Bamshad M, Nickerson D, Chong JX, Cohn DH, Krejci P, Krakow D, Duran I
EBioMedicine 2020 Dec;62:103075
EBioMedicine 2020 Dec;62:103075
Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice.
Yang CC, Chang CK, Chang MT, Shyur LF
International journal of cancer 2018 Dec 15;143(12):3248-3261
International journal of cancer 2018 Dec 15;143(12):3248-3261
Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis.
Zhang F, Lu YX, Chen Q, Zou HM, Zhang JM, Hu YH, Li XM, Zhang WJ, Zhang W, Lin C, Li XN
Cellular signalling 2017 Aug;36:67-78
Cellular signalling 2017 Aug;36:67-78
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17592-1-AP(PTK2B antibody) at dilution of 1:1500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17592-1-AP(PTK2B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PYK2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PYK2. This antibody recognizes human,mouse,rat antigen. The PYK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
