PAB3578

antibody from Abnova Corporation

Targeting: STAT2 STAT113

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB3578

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB3578, RRID:AB_1581027

Product name

STAT2 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of STAT2.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulation.

Rodriguez JJ, Wang LF, Horvath CM
Journal of virology 2003 Nov;77(21):11842-5

---

The STAT2 activation process is a crucial target of Sendai virus C protein for the blockade of alpha interferon signaling.

Gotoh B, Takeuchi K, Komatsu T, Yokoo J
Journal of virology 2003 Mar;77(6):3360-70

---

Affinity of Stat2 for the subunits of the interferon alpha receptor.

Saleh AZ, Nguyen VP, Krolewski JJ
Biochemistry 2002 Sep 17;41(37):11261-8

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of K-562 cell lysate (35 ug/lane) with STAT2 polyclonal antibody (Cat # PAB3578).

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human cancer tissue reacted with STAT2 polyclonal antibody (Cat # PAB3578) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)