Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13179-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13179-1-AP, RRID:AB_2196760
- Product name
- STAT5A antibody
- Antibody type
- Polyclonal
- Description
- STAT5A antibody (Cat. #13179-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
GNF-7, a novel FLT3 inhibitor, overcomes drug resistance for the treatment of FLT3‑ITD acute myeloid leukemia.
A Novel Mechanism of hPRL-G129R, a Prolactin Antagonist, Inhibits Human Breast Cancer Cell Proliferation and Migration.
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells.
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
C/EBPβ regulates the JAK/STAT signaling pathway in triple-negative breast cancer.
LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway.
IL-27 Rα(+) cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
García-Sancha N, Corchado-Cobos R, Blanco-Gómez A, Cunillera Puértolas O, Marzo-Castillejo M, Castillo-Lluva S, Alonso-López D, De Las Rivas J, Pozo J, Orfao A, Valero-Juan L, Patino-Alonso C, Perera D, Venkitaraman AR, Mao JH, Chang H, Mendiburu-Eliçabe M, González-García P, Caleiras E, Peset I, Cenador MBG, García-Criado FJ, Pérez-Losada J
Research square 2024 Feb 5;
Research square 2024 Feb 5;
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
Lee MR, Shin JY, Kim MY, Kim JO, Jung CK, Kang J
American journal of cancer research 2023;13(2):638-653
American journal of cancer research 2023;13(2):638-653
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W
Oncogene 2023 Nov;42(45):3331-3343
Oncogene 2023 Nov;42(45):3331-3343
GNF-7, a novel FLT3 inhibitor, overcomes drug resistance for the treatment of FLT3‑ITD acute myeloid leukemia.
Xiao X, Wang P, Zhang W, Wang J, Cai M, Jiang H, Wu Y, Shan H
Cancer cell international 2023 Nov 30;23(1):302
Cancer cell international 2023 Nov 30;23(1):302
A Novel Mechanism of hPRL-G129R, a Prolactin Antagonist, Inhibits Human Breast Cancer Cell Proliferation and Migration.
Li R, Yang Y, Lan H, Wang Y, Ge Z, Liu X, Zhou Y, Zhang W, Xian L, Yuan H
Endocrinology 2023 Nov 2;164(12)
Endocrinology 2023 Nov 2;164(12)
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Gong X, Liu X
Frontiers in oncology 2022;12:1054647
Frontiers in oncology 2022;12:1054647
Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells.
Ji Q, Zhang M, Wang Y, Chen Y, Wang L, Lu X, Bai L, Wang M, Bao L, Hao H, Wang Z
Microbial pathogenesis 2022 Oct;171:105726
Microbial pathogenesis 2022 Oct;171:105726
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
Shi X, Zhao L, Niu L, Yan Y, Chen Q, Jin Y, Li X
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
Zhang Y, Hui J, Xu Y, Ma Y, Sun Z, Zhang M, Nie L, Ye L
Chemosphere 2022 May;295:133925
Chemosphere 2022 May;295:133925
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Chen G, Lian D, Zhao L, Wang Z, Wuyun Q, Zhang N
Bioengineered 2022 Apr;13(4):11083-11095
Bioengineered 2022 Apr;13(4):11083-11095
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
Chen Y, Ma Y, Ji Q, Yang X, Feng X, Yao R, Cheng X, Li T, Wang Y, Wang Z
Frontiers in veterinary science 2021;8:756375
Frontiers in veterinary science 2021;8:756375
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Pharmaceutical biology 2021 Dec;59(1):1150-1160
C/EBPβ regulates the JAK/STAT signaling pathway in triple-negative breast cancer.
Wang S, Xia D, Wang X, Cao H, Wu C, Sun Z, Zhang D, Liu H
FEBS open bio 2021 Apr;11(4):1250-1258
FEBS open bio 2021 Apr;11(4):1250-1258
LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway.
Lv J, Yu W, Zhang Y, Cao X, Han L, Hu H, Wang C
Cancer cell international 2020;20:124
Cancer cell international 2020;20:124
IL-27 Rα(+) cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Zhao S, Liang T, Zhang C, Shi D, Jiang W, Su C, Hou G
Journal of cellular and molecular medicine 2020 Sep;24(18):10756-10767
Journal of cellular and molecular medicine 2020 Sep;24(18):10756-10767
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
Zhang Y, Zhou L, Zhang Z, Xu Q, Han X, Zhao Y, Song X, Zhao T, Ye L
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.
Li B, Hong P, Zheng CC, Dai W, Chen WY, Yang QS, Han L, Tsao SW, Chan KT, Lee NPY, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, Lung ML, He QY, Xu WW, Cheung AL
Theranostics 2019;9(6):1599-1613
Theranostics 2019;9(6):1599-1613
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Zhang Y, Wang S, Zhao T, Yang L, Guo S, Shi Y, Zhang X, Zhou L, Ye L
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, Lei W, Li C, Ai L, Tai W
BMC pulmonary medicine 2015 Feb 18;15:13
BMC pulmonary medicine 2015 Feb 18;15:13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 13179-1-AP(STAT5A antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STAT5A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STAT5A. This antibody recognizes human, mouse, rat antigen. The STAT5A antibody has been validated for the following applications: ELISA, WB, IHC analysis.