Antibody data
- Antibody Data
- Antigen structure
- References [43]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13179-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13179-1-AP, RRID:AB_2196760
- Product name
- STAT5A antibody
- Antibody type
- Polyclonal
- Description
- STAT5A antibody (Cat. #13179-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transdermal Delivery of Icariin via Microneedle Patches Attenuates Phthalate-Induced Testicular Injury.
Translation factor eIF4G2 directs CD8(+) T cell lineage commitment by selectively enabling the IL-7 receptor response.
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats.
Nuclear FGF2 orchestrates phase separation-mediated rDNA chromatin architecture to control BMSCs cell fate.
Mucosal vaccination with long-form TSLP induces migratory cDC1-mediated adaptive immunity against SARS-CoV-2 infection.
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Neutrophil extracellular traps exacerbate inflammatory arthritis by inhibiting γδ Treg cell differentiation via the AIM2 inflammasome.
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Structural characterizations and antiaging activities of hydrolyzed low-molecular-weight polysaccharides from Polygoni Multiflori Radix Praeparata.
FLT3 inhibition upregulates OCT4/NANOG to promote maintenance and TKI resistance of FLT3-ITD(+) acute myeloid leukemia.
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway.
Bardoxolone displays potent activity against triple negative breast cancer by inhibiting the TRIP13/STAT3 circuit.
Discovery of novel STAT3 inhibitors with anti-breast cancer activity: structure-based virtual screening, molecular dynamics and biological evaluation.
IRF2-driven upregulation of OAS3 promotes AML cell proliferation by modulating the JAK-STAT signaling pathway.
Targeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy.
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
The role of substance P in Th17/Treg imbalance and ocular surface damage in chronic allergic conjunctivitis.
The ubiquitin ligase Triad1 influences myeloid leukemogenesis by regulating the integrated stress response.
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation.
Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis.
Exhausted signature and regulatory network of NK cells in myasthenia gravis.
Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.
FLT3-selective PROTAC: Enhanced safety and increased synergy with Venetoclax in FLT3-ITD mutated acute myeloid leukemia.
Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.
Silk fibroin microneedles loaded with epigallocatechin gallate mitigate atrazine-induced testicular toxicity.
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
GNF-7, a novel FLT3 inhibitor, overcomes drug resistance for the treatment of FLT3‑ITD acute myeloid leukemia.
A Novel Mechanism of hPRL-G129R, a Prolactin Antagonist, Inhibits Human Breast Cancer Cell Proliferation and Migration.
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells.
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
C/EBPβ regulates the JAK/STAT signaling pathway in triple-negative breast cancer.
LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway.
IL-27 Rα(+) cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
Fang C, Li Y, You R, Wong KH, Cai T, Gan RY, Ye Y
Advanced healthcare materials 2026 Mar;15(9):e03925
Advanced healthcare materials 2026 Mar;15(9):e03925
Translation factor eIF4G2 directs CD8(+) T cell lineage commitment by selectively enabling the IL-7 receptor response.
Cui J, Zhang X, Yang Y, Shan L, Li Y, Jiang L, Xie W, Jin T, Lang X
iScience 2026 Apr 17;29(4):115313
iScience 2026 Apr 17;29(4):115313
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats.
Zhang D, Dong B, Chen J, Zhang Z, Zeng W, Liao L, Xiong X, Qin X, Fan X
Advanced biology 2025 Sep;9(9):e00028
Advanced biology 2025 Sep;9(9):e00028
Nuclear FGF2 orchestrates phase separation-mediated rDNA chromatin architecture to control BMSCs cell fate.
Zhang H, Wang Z, Liu Z, Li X, Sun W, Zhen W, Xu F, Wang R, Yin Q, Cao S, Wu M, He J, Xu J, Li Y, Yuan Q
Bone research 2025 Sep 24;13(1):80
Bone research 2025 Sep 24;13(1):80
Mucosal vaccination with long-form TSLP induces migratory cDC1-mediated adaptive immunity against SARS-CoV-2 infection.
Hu J, Zheng H, Ran W, Wang X, Liao C, Zhou J, Ye L
Journal of virology 2025 Sep 23;99(9):e0123125
Journal of virology 2025 Sep 23;99(9):e0123125
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Wang Y, Cao C, Fu T, Yu F, Qi J, Liu G, Zhang J
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Neutrophil extracellular traps exacerbate inflammatory arthritis by inhibiting γδ Treg cell differentiation via the AIM2 inflammasome.
Zeng Y, Lin J, Xiao Z, Li Z, Zheng G, Zhou Y, Li Q, Zeng C, Su Z, Yu W, Xie Z
Redox biology 2025 Nov;87:103881
Redox biology 2025 Nov;87:103881
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Huang J, Zhang W
BMC pulmonary medicine 2025 Nov 14;25(1):528
BMC pulmonary medicine 2025 Nov 14;25(1):528
Structural characterizations and antiaging activities of hydrolyzed low-molecular-weight polysaccharides from Polygoni Multiflori Radix Praeparata.
Xu W, Li XJ, Zhong YS, He JQ, Xie W, Kang YK, Ying HZ, Yu CH
Carbohydrate polymers 2025 May 15;356:123381
Carbohydrate polymers 2025 May 15;356:123381
FLT3 inhibition upregulates OCT4/NANOG to promote maintenance and TKI resistance of FLT3-ITD(+) acute myeloid leukemia.
Zhou Q, Li Z, Zhao P, Guan Y, Chu H, Xi Y
Oncogenesis 2025 Mar 29;14(1):7
Oncogenesis 2025 Mar 29;14(1):7
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway.
Wu J, Li X, Liu Y, Chen G, Li R, Jiang H, Yin W, Tong X, Cao R, Wang X, Liu X, Zhou F
Experimental hematology & oncology 2025 Mar 22;14(1):43
Experimental hematology & oncology 2025 Mar 22;14(1):43
Bardoxolone displays potent activity against triple negative breast cancer by inhibiting the TRIP13/STAT3 circuit.
Deng JH, Li HY, Liu ZY, Liang JP, Ren Y, Zeng YY, Wang YL, Mao XL
Acta pharmacologica Sinica 2025 Jun;46(6):1733-1741
Acta pharmacologica Sinica 2025 Jun;46(6):1733-1741
Discovery of novel STAT3 inhibitors with anti-breast cancer activity: structure-based virtual screening, molecular dynamics and biological evaluation.
Wang J, Zhang P, Yu Y, Yi Y, Jiang Y, Hu S
RSC medicinal chemistry 2025 Jun 18;16(6):2848-2865
RSC medicinal chemistry 2025 Jun 18;16(6):2848-2865
IRF2-driven upregulation of OAS3 promotes AML cell proliferation by modulating the JAK-STAT signaling pathway.
Zhang X, Zhong L, Zhai L, Li H, Liu B
Biochemical and biophysical research communications 2025 Jul 30;772:152064
Biochemical and biophysical research communications 2025 Jul 30;772:152064
Targeting LRBA triggers CTLA4 degradation and antitumor immunity for cancer immunotherapy.
Ge X, Yu L, Zhang L, Jia L, Meng M, He J, Bu F, Song Y, Sun G, Lv S, Mei D, Yang Y, Xu D, Zhang J, Zhang S, Wang C, Jia D, Chen Y, Gao Y, He B
Nature communications 2025 Dec 14;17(1):623
Nature communications 2025 Dec 14;17(1):623
LAX1 as a core biomarker in Alzheimer's disease and periodontitis via the STAT signaling pathway.
Guo H, Guo T, Wang X, Bao Y, Zhang Z, Xue F, Cheng D
BMC geriatrics 2025 Dec 12;26(1):69
BMC geriatrics 2025 Dec 12;26(1):69
The role of substance P in Th17/Treg imbalance and ocular surface damage in chronic allergic conjunctivitis.
Bao J, Wen Y, Wu B, Li Y, Li S, Lei F, Tian L, Chen X, Jie Y
Journal of translational medicine 2025 Dec 1;23(1):1367
Journal of translational medicine 2025 Dec 1;23(1):1367
The ubiquitin ligase Triad1 influences myeloid leukemogenesis by regulating the integrated stress response.
Wang H, Suh F, Fischietti M, Wray B, Filip SK, Faull PA, Hu L, Huang W, Liu B, Platanias LC, Eklund EA
The Journal of biological chemistry 2025 Aug;301(8):110484
The Journal of biological chemistry 2025 Aug;301(8):110484
Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation.
Shao L, Wang N, Yan Y, Tan Y, Wu Q, Lei L, Wang M, Liu L
Iranian journal of basic medical sciences 2024;27(6):685-694
Iranian journal of basic medical sciences 2024;27(6):685-694
Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis.
Williams A, Hossack DJ, Thompson N, Sim YE, Wilson C, Schuch V, Hailstorks T, Chakraborty R, Johnson EL
Frontiers in immunology 2024;15:1496610
Frontiers in immunology 2024;15:1496610
Exhausted signature and regulatory network of NK cells in myasthenia gravis.
Zhang Q, Han X, Bi Z, Yang M, Lin J, Li Z, Zhang M, Bu B
Frontiers in immunology 2024;15:1397916
Frontiers in immunology 2024;15:1397916
Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation.
Li P, Hu X, Fan Z, Sun S, Ran Q, Wei T, Wei P, Jiang Q, Yan J, Yang N, Jia C, Yang T, Mao Y, Cai X, Xu T, Zhao Z, Qian X, Qin W, Zhuang X, Fan F, Xiao J, Zheng Z, Li S
Journal of hematology & oncology 2024 Sep 2;17(1):77
Journal of hematology & oncology 2024 Sep 2;17(1):77
FLT3-selective PROTAC: Enhanced safety and increased synergy with Venetoclax in FLT3-ITD mutated acute myeloid leukemia.
Tan Y, Xin L, Wang Q, Xu R, Tong X, Chen G, Ma L, Yang F, Jiang H, Zhang N, Wu J, Li X, Guo X, Wang C, Zhou H, Zhou F
Cancer letters 2024 Jun 28;592:216933
Cancer letters 2024 Jun 28;592:216933
Cabergoline as a Novel Strategy for Post-Pregnancy Breast Cancer Prevention in Mice and Human.
García-Sancha N, Corchado-Cobos R, Blanco-Gómez A, Cunillera Puértolas O, Marzo-Castillejo M, Castillo-Lluva S, Alonso-López D, De Las Rivas J, Pozo J, Orfao A, Valero-Juan L, Patino-Alonso C, Perera D, Venkitaraman AR, Mao JH, Chang H, Mendiburu-Eliçabe M, González-García P, Caleiras E, Peset I, Cenador MBG, García-Criado FJ, Pérez-Losada J
Research square 2024 Feb 5;
Research square 2024 Feb 5;
Silk fibroin microneedles loaded with epigallocatechin gallate mitigate atrazine-induced testicular toxicity.
Fang C, Li Y, He G, Gan RY, Luo F, Lei L, Hou X, Ye Y
Journal of hazardous materials 2024 Dec 5;480:136252
Journal of hazardous materials 2024 Dec 5;480:136252
FOXA2 and STAT5A regulate oncogenic activity of KIF5B-RET fusion.
Lee MR, Shin JY, Kim MY, Kim JO, Jung CK, Kang J
American journal of cancer research 2023;13(2):638-653
American journal of cancer research 2023;13(2):638-653
Blockade of de novo pyrimidine biosynthesis triggers autophagic degradation of oncoprotein FLT3-ITD in acute myeloid leukemia.
Ma H, Cui J, Liu Z, Fang W, Lu S, Cao S, Zhang Y, Chen JA, Lu L, Xie Q, Wang Y, Huang Y, Li K, Tong H, Huang J, Lu W
Oncogene 2023 Nov;42(45):3331-3343
Oncogene 2023 Nov;42(45):3331-3343
GNF-7, a novel FLT3 inhibitor, overcomes drug resistance for the treatment of FLT3‑ITD acute myeloid leukemia.
Xiao X, Wang P, Zhang W, Wang J, Cai M, Jiang H, Wu Y, Shan H
Cancer cell international 2023 Nov 30;23(1):302
Cancer cell international 2023 Nov 30;23(1):302
A Novel Mechanism of hPRL-G129R, a Prolactin Antagonist, Inhibits Human Breast Cancer Cell Proliferation and Migration.
Li R, Yang Y, Lan H, Wang Y, Ge Z, Liu X, Zhou Y, Zhang W, Xian L, Yuan H
Endocrinology 2023 Nov 2;164(12)
Endocrinology 2023 Nov 2;164(12)
In-depth analysis of the expression and functions of signal transducers and activators of transcription in human ovarian cancer.
Gong X, Liu X
Frontiers in oncology 2022;12:1054647
Frontiers in oncology 2022;12:1054647
Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells.
Ji Q, Zhang M, Wang Y, Chen Y, Wang L, Lu X, Bai L, Wang M, Bao L, Hao H, Wang Z
Microbial pathogenesis 2022 Oct;171:105726
Microbial pathogenesis 2022 Oct;171:105726
Oral Intervention of Narirutin Ameliorates the Allergic Response of Ovalbumin Allergy.
Shi X, Zhao L, Niu L, Yan Y, Chen Q, Jin Y, Li X
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
Journal of agricultural and food chemistry 2022 Oct 19;70(41):13313-13326
MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.
Zhang Y, Hui J, Xu Y, Ma Y, Sun Z, Zhang M, Nie L, Ye L
Chemosphere 2022 May;295:133925
Chemosphere 2022 May;295:133925
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Chen G, Lian D, Zhao L, Wang Z, Wuyun Q, Zhang N
Bioengineered 2022 Apr;13(4):11083-11095
Bioengineered 2022 Apr;13(4):11083-11095
Intracellular Staphylococcus aureus Infection Decreases Milk Protein Synthesis by Preventing Amino Acid Uptake in Bovine Mammary Epithelial Cells.
Chen Y, Ma Y, Ji Q, Yang X, Feng X, Yao R, Cheng X, Li T, Wang Y, Wang Z
Frontiers in veterinary science 2021;8:756375
Frontiers in veterinary science 2021;8:756375
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Pharmaceutical biology 2021 Dec;59(1):1150-1160
C/EBPβ regulates the JAK/STAT signaling pathway in triple-negative breast cancer.
Wang S, Xia D, Wang X, Cao H, Wu C, Sun Z, Zhang D, Liu H
FEBS open bio 2021 Apr;11(4):1250-1258
FEBS open bio 2021 Apr;11(4):1250-1258
LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway.
Lv J, Yu W, Zhang Y, Cao X, Han L, Hu H, Wang C
Cancer cell international 2020;20:124
Cancer cell international 2020;20:124
IL-27 Rα(+) cells promoted allorejection via enhancing STAT1/3/5 phosphorylation.
Zhao S, Liang T, Zhang C, Shi D, Jiang W, Su C, Hou G
Journal of cellular and molecular medicine 2020 Sep;24(18):10756-10767
Journal of cellular and molecular medicine 2020 Sep;24(18):10756-10767
Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.
Zhang Y, Zhou L, Zhang Z, Xu Q, Han X, Zhao Y, Song X, Zhao T, Ye L
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
Environmental science and pollution research international 2020 Feb;27(4):3837-3848
Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.
Li B, Hong P, Zheng CC, Dai W, Chen WY, Yang QS, Han L, Tsao SW, Chan KT, Lee NPY, Law S, Xu LY, Li EM, Chan KW, Qin YR, Guan XY, Lung ML, He QY, Xu WW, Cheung AL
Theranostics 2019;9(6):1599-1613
Theranostics 2019;9(6):1599-1613
Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.
Zhang Y, Wang S, Zhao T, Yang L, Guo S, Shi Y, Zhang X, Zhou L, Ye L
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
Ecotoxicology and environmental safety 2019 Nov 30;184:109611
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation.
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, Lei W, Li C, Ai L, Tai W
BMC pulmonary medicine 2015 Feb 18;15:13
BMC pulmonary medicine 2015 Feb 18;15:13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 13179-1-AP(STAT5A antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The STAT5A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STAT5A. This antibody recognizes human, mouse, rat antigen. The STAT5A antibody has been validated for the following applications: ELISA, WB, IHC analysis.