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- References [14]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15775-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15775-1-AP, RRID:AB_2122835
- Product name
- HTRA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HTRA2 antibody (Cat. #15775-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Age-related changes in the mitochondrial, synthesis of steroids, and cellular homeostasis of the chicken ovary.
HtrA3: a promising prognostic biomarker and therapeutic target for head and neck squamous cell carcinoma.
TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria.
Protease-independent control of parthanatos by HtrA2/Omi.
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Role of Smac, survivin, XIAP, and Omi/HtrA2 proteins in determining the chemotherapeutic response of patients with cervical cancer treated with neoadjuvant chemotherapy.
Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.
Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells.
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Zhan XZ, Luo P, Zhang C, Zhang LJ, Shen X, Jiang DL, Liu WJ
Animal reproduction science 2024 Aug;267:107540
Animal reproduction science 2024 Aug;267:107540
HtrA3: a promising prognostic biomarker and therapeutic target for head and neck squamous cell carcinoma.
Chen Y, Yang J, Jin H, Wen W, Xu Y, Zhang X, Wang Y
PeerJ 2023;11:e16237
PeerJ 2023;11:e16237
TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria.
Akabane S, Watanabe K, Kosako H, Yamashita SI, Nishino K, Kato M, Sekine S, Kanki T, Matsuda N, Endo T, Oka T
Cell reports 2023 May 30;42(5):112454
Cell reports 2023 May 30;42(5):112454
Protease-independent control of parthanatos by HtrA2/Omi.
Weiß J, Heib M, Korn T, Hoyer J, Fuchslocher Chico J, Voigt S, Koudelka T, Tholey A, Adam D
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):258
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):258
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Qi Y, Xue HL, Zheng YJ, Yin YF, Xu WL, Xu JH, Wu M, Chen L, Xu LX
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses.
Straub IR, Weraarpachai W, Shoubridge EA
Human molecular genetics 2021 May 17;30(8):687-705
Human molecular genetics 2021 May 17;30(8):687-705
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
Role of Smac, survivin, XIAP, and Omi/HtrA2 proteins in determining the chemotherapeutic response of patients with cervical cancer treated with neoadjuvant chemotherapy.
Ye T, Yao H, Xu Y, Zhao X, Lu H, Zhang R
Cancer biomarkers : section A of Disease markers 2019;26(3):249-259
Cancer biomarkers : section A of Disease markers 2019;26(3):249-259
Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.
Botham A, Coyaud E, Nirmalanandhan VS, Gronda M, Hurren R, Maclean N, St-Germain J, Mirali S, Laurent E, Raught B, Schimmer A
Proteomics 2019 Dec;19(24):e1900139
Proteomics 2019 Dec;19(24):e1900139
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
Xu H, Li Y, Liu R, Wu L, Zhang C, Ding N, Ma A, Zhang J, Xie X
Neuropeptides 2019 Aug;76:101936
Neuropeptides 2019 Aug;76:101936
Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.
Völgyi K, Háden K, Kis V, Gulyássy P, Badics K, Györffy BA, Simor A, Szabó Z, Janáky T, Drahos L, Dobolyi Á, Penke B, Juhász G, Kékesi KA
Molecular neurobiology 2017 Apr;54(3):2060-2078
Molecular neurobiology 2017 Apr;54(3):2060-2078
Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells.
Wang J, Song X, Guo C, Wang Y, Yin Y
Cancer science 2016 Dec;107(12):1888-1897
Cancer science 2016 Dec;107(12):1888-1897
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Behbahani H, Pavlov PF, Wiehager B, Nishimura T, Winblad B, Ankarcrona M
Neurochemistry international 2010 Nov;57(6):668-75
Neurochemistry international 2010 Nov;57(6):668-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15775-1-AP(HTRA2 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15775-1-AP(HTRA2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HTRA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HTRA2. This antibody recognizes human,mouse,rat, monkey antigen. The HTRA2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
