Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15775-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15775-1-AP, RRID:AB_2122835
- Product name
- HTRA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HTRA2 antibody (Cat. #15775-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-OMICS study of a CHCHD10 variant causing ALS demonstrates metabolic rewiring and activation of endoplasmic reticulum and mitochondrial unfolded protein responses.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.
Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells.
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Straub IR, Weraarpachai W, Shoubridge EA
Human molecular genetics 2021 May 17;30(8):687-705
Human molecular genetics 2021 May 17;30(8):687-705
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.
Botham A, Coyaud E, Nirmalanandhan VS, Gronda M, Hurren R, Maclean N, St-Germain J, Mirali S, Laurent E, Raught B, Schimmer A
Proteomics 2019 Dec;19(24):e1900139
Proteomics 2019 Dec;19(24):e1900139
Protective effects of ghrelin on brain mitochondria after cardiac arrest and resuscitation.
Xu H, Li Y, Liu R, Wu L, Zhang C, Ding N, Ma A, Zhang J, Xie X
Neuropeptides 2019 Aug;76:101936
Neuropeptides 2019 Aug;76:101936
Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.
Völgyi K, Háden K, Kis V, Gulyássy P, Badics K, Györffy BA, Simor A, Szabó Z, Janáky T, Drahos L, Dobolyi Á, Penke B, Juhász G, Kékesi KA
Molecular neurobiology 2017 Apr;54(3):2060-2078
Molecular neurobiology 2017 Apr;54(3):2060-2078
Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells.
Wang J, Song X, Guo C, Wang Y, Yin Y
Cancer science 2016 Dec;107(12):1888-1897
Cancer science 2016 Dec;107(12):1888-1897
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Behbahani H, Pavlov PF, Wiehager B, Nishimura T, Winblad B, Ankarcrona M
Neurochemistry international 2010 Nov;57(6):668-75
Neurochemistry international 2010 Nov;57(6):668-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15775-1-AP(HTRA2 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15775-1-AP(HTRA2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HTRA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HTRA2. This antibody recognizes human,mouse,rat, monkey antigen. The HTRA2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.