Antibody data
- Antibody Data
 - Antigen structure
 - References [3]
 - Comments [0]
 - Validations
 - Immunocytochemistry [2]
 
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Validation data
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- Product number
 - ALX-804-427-C100 - Provider product page

 - Provider
 - Enzo Life Sciences
 - Proper citation
 - Enzo Life Sciences Cat#ALX-804-427-C100, RRID:AB_2051650
 - Product name
 - HtrA2/Omi (human) monoclonal antibody (196C429)
 - Antibody type
 - Monoclonal
 - Antigen
 - Synthetic peptide
 - Description
 - Protein G-affinity purified.
 - Reactivity
 - Human
 - Host
 - Mouse
 - Isotype
 - IgG
 - Antibody clone number
 - 196C429
 - Vial size
 - 100 μg
 - Storage
 - -20°C
 
Submitted references		Apoptotic death concurrent with CD3 stimulation in primary human CD8+ T lymphocytes: a role for endogenous granzyme B.
				
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
				
Immunohistochemical analysis of Omi/HtrA2 expression in stomach cancer.
				
		
	
			Laforge M, Bidère N, Carmona S, Devocelle A, Charpentier B, Senik A
Journal of immunology (Baltimore, Md. : 1950) 2006 Apr 1;176(7):3966-77
		Journal of immunology (Baltimore, Md. : 1950) 2006 Apr 1;176(7):3966-77
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia.
			Wang X, Zhu C, Wang X, Hagberg H, Korhonen L, Sandberg M, Lindholm D, Blomgren K
Neurobiology of disease 2004 Jun;16(1):179-89
		Neurobiology of disease 2004 Jun;16(1):179-89
Immunohistochemical analysis of Omi/HtrA2 expression in stomach cancer.
			Lee SH, Lee JW, Kim HS, Kim SY, Park WS, Kim SH, Lee JY, Yoo NJ
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003 May;111(5):586-90
		APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003 May;111(5):586-90
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					Supportive validation
					
									
				
		- Submitted by
 - Enzo Life Sciences (provider)
 - Main image
 
- Experimental details
 - Western blot detection of Omi/HtrA2 in HL-60cell lysate. Two protein bands of approximate molecular weight of 50 and 38kDa was detected using ALX-804-427 at 2µg/ml dilution. The two bands may represent precursor and mature form of Omi/Htra2, respectively.
 
- Submitted by
 - Enzo Life Sciences (provider)
 - Main image
 
- Experimental details
 - Immunohistochemistry using MAb to HtrA2/Omi (human) (196C429) (Prod. No. ALX-804-427) shows cytoplasmic staining in stomach tumor tissue (A) and very weak staining in normal stomach tissue (B).