ABIN356810

antibody from antibodies-online

Targeting: BAK1 BAK, BCL2L7, CDN1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN356810

Provider

antibodies-online

Product name

anti-BCL2-Antagonist/killer 1 (BAK1) (BH3 Domain), (N-Term) antibody

Antibody type

Polyclonal

Description

Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

BH3 Domain, N-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Nonredundant role of Bax and Bak in Bid-mediated apoptosis.

Cartron PF, Juin P, Oliver L, Martin S, Meflah K, Vallette FM
Molecular and cellular biology 2003 Jul;23(13):4701-12

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Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release.

Mikhailov V, Mikhailova M, Degenhardt K, Venkatachalam MA, White E, Saikumar P
The Journal of biological chemistry 2003 Feb 14;278(7):5367-76

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Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.

Bellosillo B, Villamor N, López-Guillermo A, Marcé S, Bosch F, Campo E, Montserrat E, Colomer D
Blood 2002 Sep 1;100(5):1810-6

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Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.

Werner AB, de Vries E, Tait SW, Bontjer I, Borst J
The Journal of biological chemistry 2002 Jun 21;277(25):22781-8

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Paracrine suppression of apoptosis by cytokine-stimulated neutrophils involves divergent regulation of NF-kappaB, Bcl-X(L), and Bak.

Grutkoski PS, Graeber CT, Ayala A, Simms HH
Shock (Augusta, Ga.) 2002 Jan;17(1):47-54