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- Antibody Data
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- References [2127]
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- Western blot [1]
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- Immunoprecipitation [1]
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- Product number
- 10745-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10745-1-AP, RRID:AB_2178878
- Product name
- NF-κB p65 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NF-κB p65 antibody (Cat. #10745-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SENP6 Restrains NLRP3 Inflammasome Activation via DeSUMOylation-Driven K48-Linked Ubiquitination of NLRP3 in Acute Lung Injury.
Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities.
DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling.
TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model.
Enhancement of Psoriasis Treatment by Phellodendri Chinensis Cortex Carbon Dots (PCC-CDs) Through Modulation of the HMGB1/TLR4/MAPK/NF-κB Pathway.
Benzydamine Attenuates Matrix Metalloproteinase-9 Expression Through Inhibition of ERK MAPK in Activated Human Monocytic Cells Under Hyperglycemic Condition.
Elucidating the Mechanism of Fusu Agent Against Sepsis-Induced Acute Respiratory Distress Syndrome via an Integrated Approach Combining Network Pharmacology, Molecular Dynamics Simulations, and Experimental Validation.
Transcriptomics and Network Pharmacology Reveal Anti-Inflammatory and Anti-Oxidative Stress Mechanisms of Qingxuan Runmu Yin in Dry Eye Disease.
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport.
Multi-omics reveals the protective mechanisms of Gastrodia elata ethyl acetate extract in vascular dementia.
Macrophage-biomimetic nanomedicine for targeted therapy of abdominal aortic aneurysm via Nrf2/NF-κB pathway.
Microbiota-driven therapeutic efficacy of Hyperoside in ulcerative colitis and associated anxiety.
A multi-mics exploration of programmed cell death in non-obstructive azoospermia: identifying TLR4 as a central regulator and therapeutic target.
Extracellular vesicles from Li-Qi-Yang-Yin formula attenuate LPS-stimulated inflammatory injury in human colonic epithelial cells in vitro by delivering bioactive metabolites and suppressing the oxidative stress-inflammation axis.
miR-146a/b-5p-IRAK1-NF-κB Axis Regulates Unexplained Recurrent Spontaneous Abortion.
Dual-loaded BMSCs-Metformin microgels promote cartilage repair through combined anti-inflammatory, antioxidant, and regenerative effects.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Edible Bird's Nest Attenuates Neuroinflammation and Cognitive Impairment in a Model of Chronic Fatigue Syndrome.
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
d-amino acids restrain macrophage IL-1β release through gasdermin D acetylation.
From multi-omics discovery to experimental validation: GPC4 mediates the anti-neuroinflammatory effects of Buyang Huanwu decoction via TLR4/NF-κB signaling in ischemic stroke with Qi deficiency and blood stasis syndrome.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood alleviates cerebral ischemia reperfusion injury through activating PPARγ/NF-κB pathway via suppressing arachidonic acid metabolism.
DysUFMylation reprograms immunosuppressive neutrophils to potentiate anti-PD-1 therapy in hepatocellular carcinoma.
SIRT4 regulates antiviral and autoimmune responses by promoting cGAS-mediated signaling pathways.
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Macrophage-derived galectin-3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF-κB/NLRP3 during atherosclerosis.
Transdermal Delivery of Icariin via Microneedle Patches Attenuates Phthalate-Induced Testicular Injury.
Differential Effects of Saturated and Unsaturated Fatty Acids on Colorectal Cancer via IDO1 Signaling.
Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis.
Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities.
A Biocompatible CMCHMA/F127DA Hydrogel with ROS-Scavenging Activity Prevents Postoperative Peritoneal Adhesions.
Rosa roxburghii Tratt Juice Inhibits Fluoride Exposure-Induced Bone Damage in Male Rats by Regulating the Homeostasis of the ROS/TNF-α/NF-κB Pathway.
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.
Biglycan knockdown improves Graves' orbitopathy (GO)-like features via inhibiting NF-kB and ERK signaling.
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway.
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
miR-223-3p improves macrophage polarization balance and mitochondrial metabolism to ameliorate uveitis by orchestrating P65(Lys310) acetylation through RBPJ/HDAC1 axis.
Synergistic proanthocyanidin-copper oxygen-generating microneedle enhances anti-inflammatory activity in dental pulp stem cells and macrophage efferocytosis.
Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis.
Total Extract of Folium Rhododendri Daurici alleviate MASLD by regulating PPAR and TNF signaling pathways.
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS.
Research on the compatibility mechanism of the Tingli Dazao Xiefei Decoction by multi-organ metabolomics strategy.
Inhibiting fibroblast activation protein mitigates aging-related periodontitis by blocking nuclear factor kappa B-mediated osteoclastogenesis.
Ethnopharmacological relevance and anti-inflammatory mechanisms of Lycopi Herba in diabetic nephropathy: Integrated chemical profiling and pharmacological evaluation.
Virus-inspired Ganoderma lucidum polysaccharide-functionalized adjuvant with pseudo-zwitterionic interface for potentiated nasal immunization.
Targeted inhibition of microglial C5aR1 by PMX205 mitigates post-ischemic stroke neuroinflammation and promotes functional recovery.
High-throughput RNA sequencing identifies hub genes and anti-inflammatory effects of β-caryophyllene in cerebral ischemia-reperfusion via p38MAPK/NF-κB modulation.
ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia-reperfusion injury via activation of the cGAS-STING pathway.
Inflammation-induced cell-secreted migrasome promotes IL-6 expression in the recipient cells.
Protective effects of the ethyl acetate fraction from Madeng'ai on lipopolysaccharide-induced acute lung injury in mice: Insights from integrated multi-omics analysis.
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Piperine Inhibits the Immune Checkpoint CD47 to Enhance Immunity Against Pancreatic Cancer.
λ-Carrageenan regulates antiviral responses by targeting classical NF-κB and IRF3-mediated signaling pathways.
Bushen Huoxue formula component β-Estradiol 3-acetate treats osteoarthritis through enhancing the TLR4 ubiquitination.
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Chlorogenic acid targets STING to alleviate pressure overload-induced heart failure and myocardial fibrosis.
Kaempferitrin Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction Through Suppression of the NF-κB/NLRP3 Signaling Pathway.
Periodontitis pathogen Porphyromonas gingivalis promotes chronic obstructive pulmonary disease via affecting neutrophils chemotaxis and function.
Chlorella-derived extracellular vesicle-based nanogels suppress cGAS-STING for treatment of radiation-induced lung injury.
Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary disease.
Wumei Wan ameliorates ulcerative colitis in rats by modulating the inflammation-pyroptosis-intestinal stem cell axis.
Sensitising PDAC to Gemcitabine by Suppressing NF-κB Pathway and Enhancing Apoptosis.
Functional food potential of Anoectochilus roxburghii aqueous extract: UPLC-MS profiling and in vivo efficacy in type 2 diabetic mice.
Protective effects of Curcumin-Zinc complex on inflammatory damage of IPEC-J2 cells induced by bacterial lipopolysaccharide.
MALT1 Knockdown Alleviates Multiorgan Injury and Inflammation Through Inhibiting TAK1/NF-κB Signaling Pathway-Mediated T-Helper 1 and 17 Differentiations in LPS-induced Inflammation.
A DNA-based nanodevice senses purinergic signaling and drives an immune switch for resolving inflammation.
Bu-Shen-Tian-Jing Formula alleviates oxidative-inflammatory stress in granulosa cells of polycystic ovary syndrome through AGEs-RAGE/NOX4/NF-κB pathway.
Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signaling.
Esketamine alleviates COPD-depression comorbidity in rats via MAPK/NF-κB inhibition and gut-lung-brain axis modulation.
Rhodotorula mucilaginosa JAASSRY1 Ameliorates Cyclophosphamide-Induced Immunosuppression by Regulating Gut Microbiota and Activation of Spleen TLR4/MyD88/NF-κB Pathway.
TA-Zr/Ce Nanozyme-Mediated Lipopolysaccharide Dephosphorylation: A Targeted Strategy for Sepsis Treatment with Hemoperfusion Applications.
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
Huashi Baidu granules alleviates LPS-induced acute lung injury by targeting TACE-mediated inflammatory signaling and stress granules disassembly.
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
STING knockdown blocks disease progression and inflammation in mice with alcoholic liver disease by relieving pyroptosis via suppressing NLRP3.
M1-like tumor-associated macrophages promote colorectal cancer progression through feedback activation of the IL1β/NF-κB signaling activity.
Adiponectin attenuates atherosclerosis via macrophage polarization-mediated T Cell exhaustion by modulating the NF-κB p65/PI3K/Akt signaling pathway.
Immunomodulatory effects of bacterial lysates on the IL-17 signaling pathway in an asthma mouse model.
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
A novel biomimetic nanozyme orchestrates ulcerative colitis resolution by targeting KEAP1-NRF2-ARE pathway: Redox balance restoration, colonic barrier repair, immune homeostasis regulation.
Inhibition of SCD1 attenuates neuroinflammation and brain injury after cerebral ischemia-reperfusion.
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway.
Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.
Icaritin Ameliorates Cisplatin-Induced Mitochondrial Metabolic Dysfunction-Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy.
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
Inhibition of galanin receptor 3 slows down retina degeneration in retinitis pigmentosa through modulation of inflammatory and oxidative stress response.
Artemisia Extracts Suppress H1N1 Influenza A Virus Infection by Targeting Viral HA/NA Proteins and Modulating the TLR4/MyD88/NF-κB Signaling Axis.
Study on the antioxidant and anti-inflammatory properties of different morphologies of ceria nanoenzymes with multi enzyme mimetic activity.
Exploration of borneol essential oil function in the treatment of Alzheimer's disease based on network pharmacology and experimental validation.
Knockout of the C4BPA Gene Promotes Mitophagy via Activation of the Pink1/Parkin Pathway and Alleviates the Inflammatory Response by Inhibiting the NF-κB Signalling Pathway in Bovine Mammary Epithelial Cells.
Study on the mechanism of Sangbaipi Decoction in treating acute lung injury via the inflammasome NLRP3 signaling pathway.
Electroacupuncture Attenuates Neuroinflammation and Postoperative Cognitive Dysfunction in Aged Rats by Suppressing the cGAS-STING Pathway.
Machine learning identifies a DNA repair-related risk model for bladder cancer and functionally characterizes ZWINT as a potential oncogenic factor.
Uncovering the Potential Mechanisms of Ergothioneine in Neuroinflammation Through Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and In Vitro Validation.
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
HOXA10 drives immune evasion in early lung adenocarcinoma by recruiting immunosuppressive macrophages via NF-κB/CCL2 signaling.
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Monocyte-macrophage SAMHD1 alleviates EAMG by modulating the cGAS-STING pathway.
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation.
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
S-methylmethionine ameliorates renal injury in diabetic mice by modulating macrophage inflammaging via ERK/NF-κb signaling pathway.
Mechanisms of topical Mahoniae Caulis against acute mastitis: Integrating SMR, network pharmacology, molecular docking, and experimental validation.
Nao-Xin-Tong Capsule alleviates astrocyte end-foot swelling after cerebral ischemia-reperfusion injury via NF-κB/MMP9/AQP4 signal and NF-κB/CXCL12/CXCR4 signal.
Mogrosides from S. grosvenorii ameliorate acute pharyngitis via the PI3K/AKT-NF-κB-NLRP3 signaling pathway and oxidative stress modulation.
Quercetin targeted NF-κB to regulate platelet activation and prevent arterial thrombosis.
Targeting PTGS2/NF-κB Pathway: MG-132's Role in Reducing Ischemic Stroke Injury.
Tanshinone IIA attenuates airway inflammation and airway remodeling in bronchial asthma by inhibiting p38/NF-κB and AKT/HIF-1α.
Macrophage C3aR1 Mediates Sepsis-Induced Myocardial Injury by Triggering Neutrophil Necroptosis.
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
TRIM25 triggers pyroptosis through mitochondrial DNA release in intestinal ischemia-reperfusion injury.
Development of ellagic acid-derived bismuth MOF for targeted therapy in colitis.
Zinc-doped carbon dots from natural Isatis Indigotica folium and calamine: SOD/CAT-mimetic activity targets ROS-Ca²⁺-NLRP3 axis for psoriatic dermatitis therapy.
Alkaloids of Calanthe davidii ameliorate STZ-induced diabetes by suppressing oxidative stress and inflammation.
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
Huangqi Chifeng decoction alleviates cerebral ischemia and reperfusion injury by targeting NFKBIA, NF-κB1 p105 and PIAS1 to multi-dimensionally inhibit NF-κB/NLRP3 signaling: A multi-omics analysis.
PSAT1 Promotes NSCLC Progression via the De Novo Serine Synthesis Pathway and Represents a Therapeutic Vulnerability.
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Pathogenic mechanism of Eimeria tenella EtMIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor.
Repeated photobiological regulation therapy alleviates inflammation in mice with experimental acute pancreatitis through ROS/NF-κB pathway.
Lp-PLA2-derived LysoPC drives dendritic cell immunogenic activation and Th17 inflammation in severe asthma.
Bovine serum albumin-coated metal-phenolic nanoplatform for atherosclerosis therapy via targeted delivery and inhibition of vascular smooth muscle cells proliferation.
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
ATF6 ameliorates renal warm ischemia-reperfusion injury through FHL2-mediated NF-κB signaling pathway.
Metabolic Engineering of Commensal Bacteria for Producing 5-Hydroxyindoleacetic Acid as a Therapeutic Strategy for Colitis.
Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.
Lithocarpus litseifolius and trilobatin ameliorate diabetic nephropathy through alleviating carbonyl stress by inhibiting AGEs/RAGE/NF-κB pathway.
Regulation of PSAT1 and PHGDH by m6A in endocrine-resistant breast cancer cells.
A Pathological Microenvironment-Responsive Catalytic Carbon Nanodots Release Platform Intercepting the ROS-Inflammation Cascade to Alleviate Intervertebral Disc Degeneration.
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Zr-porphyrinic MOF PCN-224 enables sequential antibacterial and inflammation-modulating PDT for periodontitis.
SRC-mediated phosphorylation of UBC9 regulates inflammatory and metabolic signaling in alcohol-associated liver disease.
LncRNA RP11-510J16.3 exacerbates sepsis-associated encephalopathy by facilitating NLRP3-dependent pyroptosis through miR-1290 sequestering.
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
Ginsenoside Compound K Plays an Anti-Inflammatory Role in Gingival Epithelial Cells Stimulated With Porphyromonas gingivalis by Regulating Pyruvate Kinase M2.
PRMT1-Mediated PARP1 Methylation Drives Lung Metastasis and Chemoresistance via P65 Activation in Triple-Negative Breast Cancer.
Modulation of EGR1 Expression by Hyperglycemia in Swine Rotator Cuff Tendons.
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Nephropathy II Decoction Attenuates Renal Fibrosis via Regulating TLR4 and Gut Microbiota Along the Gut-Kidney Axis.
FR429 from Polygonum capitatum Demonstrates Potential as an Anti-hepatic Injury Agent by Modulating PI3K/Akt Signaling Pathway.
Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis.
Lactobacillus paracasei ZJUZ2-3 inhibits gastrointestinal tumors via the IAA-induced AHR/MTDH/NF-κB axis.
SIRT4-Mediated Deacetylation of PRDX3 Attenuates Liver Ischemia Reperfusion Injury by Suppressing Ferroptosis.
Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways.
Shenlian Decoction Ameliorates LPS-Related Inflammation in db/db Mice: Coupling Network Pharmacology With Experimental Verification.
Potential diagnostic markers and therapeutic targets for DM2 and periodontitis based on bioinformatics analysis.
TENS improves CFL injury rat and regulates the intestinal microbiota.
Xiao Qing Long Tang ameliorates neutrophil extracellular trap-dendritic cells-T helper 17 cell axis in Neutrophilic Asthma.
SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway.
GFPT2 promotes paclitaxel resistance in epithelial ovarian cancer cells via activating NF-κB signaling pathway.
17(R)-RvD1 Ameliorates Liver Injury in Hyperuricemia Through Inhibiting Pyroptosis via NF-κB Signaling Pathway.
Integrative Network Pharmacology and Transcriptomics Reveal the Mechanism of Gui-Qi-Yi-Shen Granules in the Treatment of IgA Nephropathy.
Lobetyolin Suppressed Osteoclastogenesis and Alleviated Bone Loss in Ovariectomy-Induced Osteoporosis via Hindering p50/p65 Nuclear Translocation and Downstream NFATc1/c-Fos Expression.
Metabolism and Excretion of 8-O-Acetylharpagide in Rats and Identification of Its Potential Anti-Breast Cancer Active Metabolites.
Network Pharmacology and Experimental Verification: Phellodendri Chinensis Cortex-Cnidii Fructus Herb Pair Alleviates Atopic Dermatitis by Regulating the TLR4/NF-κB Pathway.
Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways.
Enhancement of retinal Müller glia's phagocytic activity against hard exudates by conbercept via activation of PPARγ-CD36 axis in diabetic retinopathy.
Hylotelephium mingjinianum Extract Attenuates Oxidative Stress and Inflammation in Experimental Periodontitis.
Isoliquiritigenin Alleviates Periodontitis by Suppressing Inflammation via NF-κB Signaling Pathway of Immune Cell.
COMMD1 Regulates Osteoclast Differentiation in Talaromyces marneffei-Induced Osteomyelitis via the NF-κB Pathway.
LT-α Facilitates the Aerobic Glycolysis and M1 Polarization of Macrophages by Activating the NF-κB Signaling Pathway in Intervertebral Disc Degeneration.
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.
Kushe Tincture Ameliorates DNCB-Induced Atopic Dermatitis by Affecting NF-Kb/JAK-STAT3 Pathway: Bioinformatics Analysis and Animal Experiment Verification.
ZnO NPs Attenuate LPS-Induced Inflammation in RAW264.7 Macrophages by Inhibiting NF-κB and JAK1-STAT1/STAT3 Pathways and Reducing ROS.
Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD.
ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway.
γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway.
NETs drive myocardial fibrosis in hypertension via an NF-κB/ferroptosis axis.
IL-18 receptor axis in allergic conjunctivitis: a multi-omics study.
Xin-Fu-Kang oral liquid improves cardiac function and attenuates miR-223-associated NF-κB/NLRP3 pyroptotic signaling in chronic heart failure.
LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.
Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance proteins.
Isodon lophanthoides alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis.
Jianpi-Huayu-Jiedu formula improves metabolic dysfunction-associated steatohepatitis through ameliorateing hepatic oxidative stress and lipid accumulation in vivo and in vitro.
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.
Umbilical cord stem cells therapy against bacterial pneumonia based on zebrafish pneumonia model.
Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells.
Mn(3)O(4) nanozyme-based anti-inflammatory therapy modulates microglial phenotype by downregulating TLR4/NOX2 expression and further alleviates Alzheimer's disease pathology.
Qing-Re-Hua-Shi Decoction ameliorates DSS-induced colitis by modulating multiple signaling pathways and remodeling the gut microbiota and metabolite profile.
Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1-Nrf2 axis.
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway.
JOSD2 alleviates acute kidney injury through deubiquitinating SIRT7 and negativity regulating SIRT7-NF-κB inflammatory pathway in renal tubular epithelial cells.
Influence and molecular mechanism of cinnamaldehyde against ventricular arrhythmia via the TAK1-p38MAPK-NLRP3 pathway.
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Regulation of macrophage phenotypes via NF-κB/NLRP3 and HIF1α/p53 pathways by fuco-galactoglucan from Agrocybe aegerita.
Resveratrol alleviates lipopolysaccharide-induced acute lung injury through blocking the excessive autophagy/mitophagy via SIRT1/PGC-1α and TNF/NF-κB/JNK pathways.
The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25.
Insufficient BK channel function enhances NF-κB nuclear translocation and promotes IL-6 synthesis in vascular smooth muscle cells induced by AT1-AA.
Hypoxia-Inducible Factor-1α-Induced Astrocytic D-Dopachrome Tautomerase Activates Microglial Inflammatory Response following Spinal Cord Injury.
The mechanism of action in Mussaenda pubescens (Yuye Jinhua) against influenza A virus: Evidence from in vitro and in vivo studies.
Multi-omics analyses reveal that hesperidin ameliorates high-altitude pulmonary hypertension by restoring gut-lung axis homeostasis.
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Donkey Milk Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis by Protecting Gut Barrier Function, Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway, and Modulating Gut Microbiota.
Flavonoids in Rosa roxburghii Tratt Fermentation Broth Ameliorate Obesity via DNMT3a/SIRT1-Mediated Epigenetic Modulation.
Effect of temperature on acute kidney injury in a rat model of renal ischemia‒reperfusion.
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD-1 Blockade.
Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.
DCAAA mitigates neuroinflammation and microglial pyroptosis in spinal cord injury by inhibiting PI3K/AKT/NF-κB and NLRP3/caspase-1/GSDMD signaling.
ANXA4 Alleviates Cardiomyocyte Injury Associated With Ischemia-Reperfusion by Interfering With NFκB p50's Transcriptional Activation of RAGE.
Garlic essential oil alleviate oxidative stress, inflammation and microbiota dybiosis from small intestinal damage in lipopolysaccharide-challenged weaned piglets.
Yak milk ameliorates chronic alcohol-induced brain injury in mice by modulating the gut microbiota and suppressing the TLR4/NF-κB pathway.
Nicotinamide metabolic dysregulation plays a key role in Benzo[a]pyrene-induced adverse birth outcomes: Evidence from multi-omics profiling, experimental and epidemiological validation.
Fucoxanthin ameliorates high-fat diet-induced kidney injury in mice.
A Novel Function of Glycerol Kinase Alleviates LPS-Induced Inflammatory Responses by the p38/STAT3 Pathway and Mitigates ROS Generation in Kupffer Cells.
Systematic reevaluation on the antipyretic, analgesic effects, and uncover the mechanisms of Chaiqin Qingning capsule, a traditional Chinese medicine, via establishing lipopolysaccharide - induced fever models, physical and chemical - stimuli pain models.
Penthorum chinense Pursh extract ameliorates lupus nephritis disease in MRL/lpr mice via the PPARγ/NFκB signaling axis.
Atractylenolide III attenuates acute kidney injury through phosphorylation of PIK3CA: Functional activation and molecular interaction analysis.
Platycodon grandiflorum: A promising medicinal and food homologous plant for cigarette smoke-induced chronic bronchitis.
Protective effect and mechanism of Zhuang medicine Tinosporae Radix on LPS-induced neuroinflammation.
Prunella vulgaris seed oil alleviates cancer related fatigue through hypothalamic inflammation and CRH regulation.
Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands.
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Astaxanthin attenuates AFB1-induced hepatotoxicity by activating Nrf2 and inhibiting the NF-κB signaling pathway.
Tetrabromophthalate bis(2-ethylhexyl) ester (TBPH) exposure induces renal inflammation injury by activating MAVS-IRF3 signaling pathway in vitro and in vivo models.
Ginsenoside F4 inhibits colorectal cancer progression by boosting dendritic cell maturation and remodeling the tumor microenvironment.
A hydrogel-based drug delivery system reduces inflammation and oxidative stress to alleviate intervertebral disc degeneration.
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
L-selectin Promotes Migration, Invasion and Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via NF-kB Signaling Pathway.
Neutrophils loaded NAD(+) impede TLR4/NF-κB/NLRP3 pathway for sepsis treatment.
Activation of the TLR2/NF-κB signaling axis by capsid proteinVP1 of feline calicivirus promotes IL-1β expression in vitro.
African swine fever virus pMGF505-9R enhances RIG-I-like receptor signaling by promoting RING finger protein 125 autoubiquitination.
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Crosstalk between YAP-TEAD and PPAR suppresses HIV-1 LTR transcription in vitro.
Research on the Pharmacodynamic Substances and Mechanism of Action of Tibetan Medicine Liuwei Muxiang Powder in the Treatment of Ethanol-Induced Gastric Ulcer Model of GES1 Cell.
Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection.
5-HT regulates resistance to aumolertinib by attenuating ferroptosis in lung adenocarcinoma.
Unlocking the gut-lung axis: Feixin decoction as a novel modulator in hypoxic pulmonary hypertension.
Removal and toxic intervention of polystyrene microplastics and nanoplastics by magnetic nano-Fe(3)O(4) in spermatogonial GC-1 cells.
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway.
Shikonin Ameliorates Alcohol-Associated Liver Disease by Reducing Oxidative Stress, Apoptosis, and Inflammation.
Role of SLC16A10 in Psoriasis Through the Regulation of Arachidonic Acid Metabolism in Keratinocytes.
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds.
TGF-β3-mediated phagocytosis protects mammary epithelial cells of ketotic dairy cows against metabolic stress-induced inflammatory damage.
Potential Mechanism of Qiju Dihuang Pill in Treating Primary Sjogren's Syndrome Revealed by Network Pharmacology and Experimental Verification.
EOAI3402143 inhibits lung adenocarcinoma progression through the NF-κB/NR4A1 pathway.
ADAP-METTL3 modulates the inflammatory responses of macrophages via m(6)A modification of Spry1.
Gut microbiota dysbiosis exacerbates post-stroke depression via microglial NLRP3 inflammasome activation.
Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough.
A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis.
Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota-bile acid axis in mice by FXR signaling pathway.
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Strand-specific functions of miR-301a-3p and -5p drive opposing roles in pancreatic cancer via ferroptosis and pyroptosis.
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
A Therapeutic System Regulating Iron Metabolism in CD63(+) Macrophage Subsets Activates Anti-tumor Immunity for Bone Metastasis Therapy.
Activation of Sirtuin3 by 6,4'-Dihydroxy-7-methoxyflavanone Against Myoblasts Senescence by Attenuating D-Galactose-Induced Oxidative Stress and Inflammation.
Alpinetin Alleviates Cardiac Inflammation and Remodeling via TLR4/MyD88/NF-κB Signaling Pathway in Rats with Acute Myocardial Infarction.
Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation.
Ginsenoside Rb3 modulates gut microbiota to alleviate cerebral inflammation and ferroptosis via the NLRP3/NF-κB/GPX4 pathway in rats with cerebral ischemia/reperfusion injury.
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Thrombopoietin mitigates neuronal death by enhancing mitophagy and suppressing NLRP3 inflammasome activation under oxygen-glucose deprivation conditions.
Dexmedetomidine regulates sleep rhythm and alleviates neuroinflammation in rats under high-altitude hypoxia.
MTFR1 Promotes Proliferation and Metastasis of Triple-Negative Breast Cancer by Regulating Mitochondrial Metabolism.
Identification of an IL17RC missense variant in a Chinese family with multiple osteochondromas and ankylosing spondylitis.
Sorafenib induces intestinal toxicity by disturbing gut microbiota and activating the LPS/TLR4/NF-κB signaling pathway in mice.
Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1.
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Hesperidin Inhibits Oxidative Stress and Apoptosis of Granulosa Cells in Polycystic Ovarian Syndrome Through the JAK2/STAT3 and PI3K/AKT Pathways.
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
DNA damage agents trigger iNKT cell-mediated elimination of AML cells through activation of NF-κB/HLA-DRB6/CD1d pathway.
Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA.
Sulfasalazine disrupts the interaction between TNFα and TNFR1 thus inhibiting NF-kB signaling activation to promote bone fracture healing.
Ferrum@albumin assembled nanoclusters inhibit NF-κB signaling pathway for NIR enhanced acute lung injury immunotherapy.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
Theaflavin-3,3'-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice.
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Harnessing NLRX1: a new frontier in mitigating inflammation in pulmonary hypertension.
Exploration of new azole derivatives containing ethanolamine moiety as anti-UC agents by inhibiting NF-κB/MAPK pathways.
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
SUN5 interacts with TRIM28, enhancing IκBα ubiquitination to promote glycolysis in colorectal cancer cells.
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response.
Antitumor immunity of alcohol-soluble polysaccharide from Nostoc sphaeroides in non-small cell lung cancer.
Metabolomics and network pharmacology revealing the transdermal moxibustion compounds and their therapeutic mechanisms for rheumatoid arthritis.
Huang-Lian-Jie-Du decoction alleviates diabetic ischemic stroke by modulating gut microbiota-derived short-chain fatty acids.
Qihuang Yishen formula attenuates renal tubular injury by modulating inflammation via the cGAS/STING pathway in diabetic kidney disease.
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone.
Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke rat.
Targeting ICAM1 through LIF-mediated NF-κB/JAK2-STAT3 crosstalk protects nucleus pulposus from IL-1β-driven pyroptosis to ameliorate intervertebral disc degeneration.
Downregulation of oar-miR-125b Drives Blood-Brain Barrier Breakdown Through the TNFSF4-NF-κB Inflammatory Axis in Enterococcus Faecalis Meningitis.
CLOCK-mediated acetylation of NF-κB p65 drives immune evasion in breast cancer.
Identification of IL1R1 as a potential key PANoptosis-related gene in myocardial ischemia-reperfusion injury using machine learning.
Cordycepin Mitigates Sepsis-Associated Encephalopathy by Promoting Microglial M2 Polarization via the IL-17a/IL-17RA/NF-κB Axis.
Integrative Transcriptomic and Metabolomic Analysis Reveals That Acanthopanax senticosus Fruit Ameliorates Cisplatin-Induced Acute Kidney Injury by Suppressing the NF-κB/PI3K-AKT Pathway via UGT1A1 Regulation.
Orosomucoid 1 Participates in Alveolar Hypercoagulation and Fibrinolytic Inhibition Involving NF-κB Signaling Pathway in LPS-Induced ARDS.
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis.
Tetrandrine enhances cognition in SAH rats via gut microbiota CYP51 and TLR4 signaling.
Exercise increases bone mass by lactate/Gpr81 signaling pathway.
Folate Attenuates Ulcerative Colitis via PI3K/AKT/NF-κB/MLCK Axis Inhibition to Restore Intestinal Barrier Integrity.
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Underlying metabolic syndrome exacerbates Vibrio vulnificus-induced acute kidney injury via systemic Th17/Treg dysregulation.
Remote ischemic conditioning as a potential therapy for Parkinson's Disease: Inhibiting TLR4-Driven neuroinflammation and oxidative damage.
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Early Potentially Irreversible Cardiac Damage in Fabry Disease Precedes Gb3 Inclusion Body Formation.
Gastrodin Ameliorates Tau Pathology and BBB Dysfunction in 3xTg-AD Transgenic Mice by Regulating the ADRA1/NF-κB/NLRP3 Pathway to Reduce Neuroinflammation.
Eicosapentaenoic acid (EPA) reduced lipopolysaccharide-stimulated inflammatory response of RAW264.7 cells via the miR-125b-5p/CREB axis.
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Phosphorylation-driven regulation of SIRT1 in muscle senescence: Insights from molecular dynamics simulation and experimental validation.
Reno protective potential of taxifolin liposomes modified by chitosan in diabetic mice.
The Combination of MIF Inhibitor and AEP Targeted Inhibitor to Reduce Lung Metastasis in Breast Cancer and Its Mechanism.
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Neuroprotective effects of hirudin against cerebral ischemia-reperfusion injury via inhibition of CCL2-mediated ferroptosis and inflammatory pathways.
ZACN Associated with Poor Prognosis Promotes Proliferation of Kidney Renal Clear Cell Carcinoma Cells by Inhibiting JTC801-Induced Alkaliptosis.
Targeting HPK1 inhibits neutrophil responses to mitigate post-stroke lung and cerebral injuries.
Herbal-based Xuebijing injection ameliorated vascular endothelial dysfunction via inhibiting ACLY/MYB/RIG-I axis in sepsis-associated lung injury.
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease.
β-Hydroxybutyrate aggravates LPS-induced inflammatory response in bovine endometrial epithelial cells by activating the oxidative stress/NF-κB signaling pathway.
Targeting inflammation and necroptosis in diabetic kidney disease: A novel approach via PPARα modulation.
Bicuculline ameliorates metabolic dysfunction-associated steatotic liver disease by inhibiting the nuclear factor-kappa B pathway and reducing lipid accumulation.
Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury.
Tetrandrine Improves Ventricular Remodeling and Inflammation via Inhibition of the MAPK/NF-κB Pathway.
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Aryl Hydrocarbon Receptor-Dependent miRNA-382-5p Mediates the Classical Pyroptosis Induced by Foodborne Benzo(a)pyrene through Targeting IκB in Liver.
Huatanhuoxue decoction alleviates airway inflammation by regulating IL-17A signaling pathway in obese asthmatic mice.
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia.
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
Protective Effect of Obeticholic Acid on Sepsis-Induced Liver Dysfunction via Regulating Bile Acid Homeostasis.
THG-1/TSC22D4 Promotes IL-1 Signaling through Stabilization of TRAF6 in Squamous Cell Carcinoma.
Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway.
Gut microbiota contributes to obstructive sleep apnea-induced hypertension by gut-heart axis in mice.
Effects of Adipose-Derived Mesenchymal Stem Cell-Secretome on Pyroptosis of Laparoscopic Hepatic Ischemia Reperfusion Injury in a Porcine Model.
Multi-Omics Unveils Inflammatory Regulation of Fermented Sini Decoction Dregs in Broilers Infected with Avian Pathogenic Escherichia coli.
HDLR-SR-BI Expression and Cholesterol Uptake are Regulated via Indoleamine-2,3-dioxygenase 1 in Macrophages under Inflammation.
Comprehensive wound healing using ETN@Fe(7)S(8) complex by positively regulating multiple programmed phases.
Inhalable neutrophil-mimicking nanoparticles for chronic obstructive pulmonary disease treatment.
Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.
ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation.
CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment.
Resveratrol Alleviates Liver Fibrosis by Targeting Cross-Talk Between TLR2/MyD88/ERK and NF-κB/NLRP3 Inflammasome Pathways in Macrophages.
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall-Derived Carbon Dots.
Structural characterization of an apple polysaccharide and its anti-inflammatory effect through suppressing TLR4/NF-κB signaling.
Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity.
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings.
Ferroptosis-Related Genes Are Effective Markers for Diagnostic Targets of Crohn's Disease.
Photothermal Coating on Zinc Alloy for Controlled Biodegradation and Improved Osseointegration.
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Network pharmacology and in vivo study: Unraveling the therapeutic mechanisms of Panax ginseng in potentially treating ulcerative colitis.
Alleviation of inflammation in paraventricular nucleus and sympathetic outflow by melatonin efficiently repairs endplate porosities and attenuates spinal hyperalgesia.
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
Chrysin ameliorates dextran sulfate-induced ulcerative colitis in mice by modulating inflammation and gut microbiota.
Isorhamnetin ameliorates hyperuricemia by regulating uric acid metabolism and alleviates renal inflammation through the PI3K/AKT/NF-κB signaling pathway.
Probiotic nanovesicles encapsulating baicalin: a strategy to overcome colorectal cancer.
Unveiling the anti-inflammatory mechanism of exogenous hydrogen sulfide in Kawasaki disease based on network pharmacology and experimental validation.
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
Effect of Benzyl Isothiocyanate on Anaplastic Thyroid Cancer Evaluated by Network Pharmacology Combined with Experiments.
Medium- and long-chain triacylglycerols as enteral nutrition enhancing the nutritional status of postoperative rats undergoing chemotherapy by increasing the bioavailability of functional fatty acids.
Glycidol induces necroptosis and inflammation through autophagy-necrosome pathway in renal cell and mice.
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
GIT2 negatively regulates the NF-κB pathway directly or indirectly by regulating TRAF3 expression to promote osteogenic differentiation of BMSCs.
The safety assessment of cinnabar: Effects of co-administration with selenium on renal toxicity in mice.
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
β-Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti-Inflammatory Pathway.
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Black phosphorus nanosheets activate tumor immunity of glioblastoma by modulating the expression of the immunosuppressive molecule PD-L1.
Alhagi camelorum seed polysaccharide alleviates methylglyoxal-induced skin damage via antioxidant and anti-inflammatory actions.
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
SFTSV NSs degrades SAFA via autophagy to suppress SAFA-dependent antiviral response.
Prostaglandin E2 alleviates inflammatory response and lung injury through EP4/cAMP/IKK/NF-κB pathway.
Gen-17, a beta-methyl derivative of Genipin, attenuates LPS-induced ALI by regulating Keap1-Nrf2/HO-1 and suppressing NF-κB and MAPK-dependent signaling pathways.
Targeted lipidomic reveals dietary LA/n-3 PUFAs regulate inflammation and redox status via oxylipins in bivalves.
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
Extraction technology, component analysis, and the immunomodulatory effects in immunosuppressed broilers of total flavonoids extract from the thorns of Gleditsia sinensis Lam.
Acupuncture protects against ischemic stroke by inhibiting the NF-κB pathway.
Curcumol Ameliorates Cisplatin-induced Nephrotoxicity by Targeting TAK1 and Inhibiting MAPK and NF-κB Pathways.
Construction of a toxicity pathway from activation of the TLR4/NF-κB/NLRP3 axis to Parkinson's disease-like non-motor symptoms in mice.
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons.
18β-glycyrrhetinic acid improves pulmonary hypertension by regulating the vascular non-inflammatory molecule-1/L-arginine/nitric oxide signaling pathway.
Discovery of novel rigid STING PROTAC degraders as potential therapeutics for acute kidney injury.
Unveiling the mechanisms of mechanical loading-induced knee osteoarthritis through transcriptomics.
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Euphorbia humifusa Willd. extract alleviates imiquimod-induced psoriasis-like skin lesions in mice by modulating the IL-17 signaling pathway.
Overexpression of S100B promotes depressive-like behaviors in stroke-induced rats by modulating the PI3K/AKT/NF-κB pathway.
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Mechanisms of Aletris spicata (Thunb.) Franch. Extract in Asthma Therapy: Oxidative Stress, Inflammation, and Gut Microbiota.
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway.
Long-Term Treatment with Low-Level Arsenite Induces Aberrant Proliferation and Migration via Redox Rebalance in Human Urothelial Cells.
Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p.
Guyuan Jiannao decoction improves neurovascular unit dysfunction by regulating PI3K/AKT/NF-κB signaling pathway in cerebral small vessel disease rats.
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Sea Cucumber Fucoidan Inhibits Helicobacter pylori Gastritis via MAPK/NF-κB Signaling and Gut Microbiota Modulation.
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
LMO2 confers value as a potential immunotherapy marker in pan-cancer analysis and inhibits progression of Clear Cell Renal Cell Carcinoma.
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
Platelet-rich plasma improves cyclophosphamide-induced interstitial cystitis in rat models through the toll-like receptor 4/nuclear factor-kappa B signalling pathway.
Alpha-lipoamide prevents acute kidney injury in mouse by inhibiting renal tubular epithelial cell pyroptosis.
Discovery of a novel BCL-2 inhibitor GW806742X for the treatment of TNBC.
Ji-Ming-San enhances intestinal circadian rhythms and mitigates colitis in mice: The role of epithelial RORα.
Bovine collagen peptides and peptide-calcium complexes inhibit RANKL-induced osteoclast differentiation in RAW 264.7 macrophages.
Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.
Mechanism of hydroxychloroquine in the treatment of obstetric antiphospholipid syndrome by inhibiting NETs-induced trophoblast pyroptosis.
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke.
Ginsenoside Rh2-Liposome Potentiate Vaccine Immunity through Enhanced MHC‑I Presentation.
Parishin C Attenuates Oxidative Stress and Inflammation in HT22 Hippocampal Neurons and BV2 Microglia Through Nrf2 Signaling Pathway.
Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways.
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Investigation of the effect and mechanism of Fei Re Pu Qing powder in treating acute lung injury (ALI) by modulating macrophage polarization via serum pharmacology and network pharmacology.
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
FGA, a new target of histone acetylation, inhibits apoptosis of granulosa cells in follicles.
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
SIGLEC1 ubiquitination and degradation induced by MARCHF3 protects ARPE19 retinal cells from high glucose-induced oxidative stress, inflammation, and apoptosis.
Machine learning-based integration develops a hypoxia-derived signature for improving outcomes in glioma.
Platelet NLRP6 protects against microvascular thrombosis in sepsis.
Engineered Exosomes Delivering bta-miR-223 Alleviate Staphylococcus aureus-Induced Mastitis in Mice via the TLR4/NF-κB Signaling Pathway.
EIF4A3-induced circPRKAR1B promotes esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB induced CCL3 secretion.
Immune cell diversity and regenerative markers reveal interactions among macrophages, rodlet cells, and stem cells in the kidney of Poecilia sphenops.
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Protective Effects of Ginseng Soluble Dietary Fiber and Its Fecal Microbiota Extract on Antibiotic-Induced Gut Dysbiosis Obese Mice.
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Gut microbiota-derived indoleacetic acid attenuates neuroinflammation and neurodegeneration in glaucoma through ahr/rage pathway.
A Novel Effect of Id2 in Microglia TNFα Regulation.
Sirt1 blocks nucleus pulposus and macrophages crosstalk by inhibiting RelA/Lipocalin 2 axis.
Downregulation of the immunoproteasome subunit PSMB8 attenuates sepsis-associated acute kidney injury through the NF-κB pathway.
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
Highly oxygenated ent-abietane diterpenoid lactones from Euphorbia peplus and their anti-inflammatory activity.
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
Oxymatrine, a novel TLR2 agonist, promotes megakaryopoiesis and thrombopoiesis through the STING/NF-κB pathway.
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
Echinacoside attenuates Klebsiella pneumoniae-induced pneumonia via inhibition of the TLR4/NF-κB signaling.
Protective Effects of α-Linolenic Acid on Liver Inflammation and Oxidative Stress Induced by Lipopolysaccharide in Broilers.
Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells.
Ellagic acid alleviates DSS-induced ulcerative colitis by inhibiting ROS/NLRP3 pathway activation and modulating gut microbiota in mice.
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
G(1-5)-EM2, a multi-targeted agonist to opioid and growth hormone secretagogue receptors exhibited nontolerance forming antinociceptive effects in a mouse model of burn pain.
Regulator of G protein signaling-1 facilitates ovarian cancer development by modulating NF-kB signal pathway.
Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms.
The structural features and anti-inflammatory properties of a glucogalactan from Holotrichia diomphalia Bates (Qi Cao).
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
Extract of Tinospora sinensis alleviates LPS-induced neuroinflammation in mice by regulating TLR4/NF-κB/NLRP3 signaling pathway.
Huang-Lian-Jie-Du Decoction alleviates diabetic encephalopathy by regulating inflammation and pyroptosis via suppression of AGEs/RAGE/NF-κB pathways.
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota.
Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.
Identification of glutamine as a potential therapeutic target in dry eye disease.
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
Dual neutralization of TGF-β and IL-21 regulates Th17/Treg balance by suppressing inflammatory signalling in the splenic lymphocytes of Staphylococcus aureus infection-induced septic arthritic mice.
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
tRNA-derived fragment 3031B regulates human anterior cruciate ligament cell proliferation and survival by targeting RELA.
CUMS induces depressive-like behaviors and cognition impairment by activating the ERS-NLRP3 signaling pathway in mice.
α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation.
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
Diosmetin-7-O-β-D-glucopyranoside from Pogostemonis Herba alleviated SARS-CoV-2-induced pneumonia by reshaping macrophage polarization and limiting viral replication.
Human leukocyte antigen DR alpha inhibits renal cell carcinoma progression by promoting the polarization of M2 macrophages to M1 via the NF-κB pathway.
Marein ameliorates the progression of osteoarthritis: An in vitro and in vivo studies.
Long-term copper exposure induced pyroptosis and inflammation of rat spleen through intestinal-splenic axis.
Synthesis and biological evaluation of lappaconitine analogues as potential anti-neuroinflammatory agents by side chain modification and scaffold hopping strategy.
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen-glucose deprivation/reoxygenation.
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
Multi-omics analysis explore the mechanism of deoxynivalenol inhibiting rabbit appetite through microbial-gut-brain axis.
Lauric acid-mediated gelatin/hyaluronic acid composite hydrogel with effective antibacterial and immune regulation for accelerating MRSA-infected diabetic wound healing.
Melatonin alleviates oxidative stress and inflammation of Leydig cells of Min pig through SIRT1 pathway.
Exploring the effects of lactulose on lung-intestinal tissue-associated factors and the TLR4/NF-κB signaling pathway in COPD rats based on lung-gut axis theory.
Molecular insights of T-2 toxin exposure-induced neurotoxicity and the neuroprotective effect of dimethyl fumarate.
Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential.
Integration of transcriptomics and metabolomics reveals the mechanism of Glycyrrhizae Radix Et Rhizoma extract inhibiting CCL5 in the treatment of acute pharyngitis.
Donkey milk supplementation alleviates renal fibrosis of chronic kidney disease by enhancing anti-inflammatory ability.
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Repressing cytokine storm-like response in macrophages by targeting the eIF2α-integrated stress response pathway.
Fraxin inhibits ovariectomized-induced bone loss and osteoclastogenesis by suppressing ROS activity.
Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways.
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via the PI3K-AKT signaling pathway.
Exosomal miR-203 from bone marrow stem cells targets the SOCS3/NF-κB pathway to regulate neuroinflammation in temporal lobe epilepsy.
Long non-coding RNA NRIR inhibits osteogenesis in peri-implantitis by promoting NLRP3 inflammasome-mediated macrophage pyroptosis.
Structural Characterization of APSN from Astragalus membranaceus and Its Potential Therapeutic Effect on Immune Dysregulation and Tissue Damage.
L-Theanine Mitigates Acute Alcoholic Intestinal Injury by Activating the HIF-1 Signaling Pathway to Regulate the TLR4/NF-κB/HIF-1α Axis in Mice.
Pulsed electromagnetic field ameliorates the progression of osteoarthritis via the Sirt1/NF-κB pathway.
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses.
Jiawei Ermiao Granules (JWEMGs) clear persistent HR-HPV infection though improving vaginal microecology.
Investigating the possible mechanism of Cornus officinalis in the therapy of ischemic stroke by UHPLC-Q-TOF-MS, network pharmacology, molecular docking, and experimental verification.
Chronic treatment of mixture of two iridoids proportional to prescriptional dose of Yueju improves hippocampal PACAP-related neuroinflammation and neuroplasticity signaling in the LPS-induced depression model.
4D-DIA-based proteomics analysis reveals the protective effects of Pidanjiangtang granules in IGT rat model.
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells.
Propofol inhibits glioma growth by blocking the formation of the NF-κB/LGI4 feedback loop to activate TP53 self-transcription.
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
HNRNPC-Mediated m6A Epitranscriptomics Drives CD80-Dependent Tubular Dysfunction in Sepsis-Induced AKI.
Alpha Ketoglutaric Acid attenuates LPS Induced Inflammatory Response by Inhibiting the PKCε/MAPK/P65 Signaling Pathway and Inhibit Oxidative Stress in Kupffer Cells.
TAK-981 potentiates doxorubicin immunocide in triple-negative breast cancer by IFN I-dependent NK cell stimulation.
The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma.
Intelligent responsive PVA hydrogel loaded with composite MXene nanozyme enables efficient myocardial infarction repair by disrupting the oxidative stress-inflammation cascade.
Pan-cancer analysis identifies adhesion G protein-coupled receptor G6 as a potential prognostic and immunotherapeutic biomarker with its functional validation.
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury.
Indole modulates lipoteichoic acid-induced inflammatory response in duck intestinal epithelial cells.
Pyridostigmine attenuates placental-ischemia-upregulated placental angiotensin II type 1 receptor in rats.
Trimethylamine-N-oxide damages astrocytes and lymphatic endothelial cells in the cerebral lymphatic system.
E3 ubiquitin ligase Pellino1 suppresses acinar cell necroptosis and alleviates severe acute pancreatitis by promoting ubiquitin-dependent receptor-interacting protein kinase 3 (RIP3) degradation.
The Therapeutic Potential of Lactobacillus crispatus for Chronic Endometritis: A Comprehensive Clinical Trial and Experimental Investigation.
Eukaryotic translation elongation factor 1 alpha 1 facilitates coxsackievirus B replication through interacting with PABP, viral protein 3 CD and viral RNA.
Silybin ameliorates Pb-induced learning and memory impairment by inhibiting STAT3/hnRNP U/REST and NFκB/hnRNP U.
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Hesperidin-β-Cyclodextrin inclusion complexes: A novel approach for preventing and treating acute lung injury caused by seawater drowning.
FUT3-B3GNT3 interaction promotes pancreatic cancer progression and chemoresistance via NF-κB signaling mediated autophagy.
Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis.
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Taurine Attenuates M1 Macrophage Polarization and IL-1β Production by Suppressing the JAK1/2-STAT1 Pathway via Metabolic Reprogramming.
Neutrophil-macrophage crosstalk via NETs-IL-17/VEGF/S100A9 axis promotes hepatocellular carcinoma progression.
Complement C4b as a key mediator of synaptic loss and cognitive decline in brain aging.
Butin inhibits osteoarthritis progression by modulating the Nrf2/HO-1 signaling pathway and inhibiting NF-κB signaling.
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Expression and Biological Activity of Recombinant Type IV Collagen.
CEBPD-mediated SGPP2 upregulation via PERK/ER stress in endothelial cells disrupts S1P homeostasis and impairs angiogenesis in chronic endometritis.
Hedyotis diffusae herba -Scutellaria Barbata herba drug pair suppresses prostate cancer by inducing apoptosis.
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling.
18β-glycyrrhetinic acid-amantadine hybrid: Synthesis and anti-EMCV activity via NF-κB modulation.
Triptolide combined with arsenic trioxide induces apoptosis of myelodysplastic syndrome cells by inhibiting the NF-κB signaling pathway.
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Resolvin D1 Modulates the Inflammatory Processes of Human Periodontal Ligament Cells via NF-κB and MAPK Signaling Pathways.
Effect of Limosilactobacillus reuteri SBC5-3 Cell-free Supernatant on Growth Performance, Intestinal Inflammation, and Microbiota in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88.
Auranofin facilitates gemcitabine sensitivity by regulating TXNRD1-related ferroptosis in pancreatic ductal adenocarcinoma.
RPPH1 promotes the progression of High-Risk acute myeloid leukemia through NF-κB signaling and Th17 expression.
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
Exosomes Derived From Calycosin-Exposed Prostate Stromal Cells Inhibit Lipopolysaccharide-Induced Epithelial Cells Inflammatory Injury.
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
NOD3 Reduces Sepsis-Induced Acute Lung Injury by Regulating the Activation of NLRP3 Inflammasome and the Polarization of Alveolar Macrophages.
Polyphenol-based self-assembled nanoparticles treating uveitis by inflammation-oxidative stress suppression.
IFI16 Induced by p53 Activates the NF-κB Pathway to Counteract Cisplatin-Induced Apoptosis in Cervical Cancer Cells.
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Ghrelin/GHSR system attenuates collagen-induced arthritis in mice and ameliorates inflammation in human rheumatoid arthritis fibroblast-like synoviocytes.
BPA Exacerbates Zinc Deficiency-Induced Testicular Tissue Inflammation in Male Mice Through the TNF-α/NF-κB/Caspase8 Signaling Pathway.
The β2-adrenergic receptor modulates activity of porcine alveolar macrophages in response to Actinobacillus pleuropneumoniae infection.
Targeting Reticulin 4 (RTN4) Within Small Extracellular Vesicles Combats Metastasis and Reinforces Immunotherapy in Triple-Negative Breast Cancer.
Cascade Regulation of Blood Clot Stabilization-Cell Migration-Osteogenic Differentiation by Hollow Hydrogels for Periodontal Bone Regeneration and Repair.
SERPINF1 knockdown attenuates chondrocyte senescence, hypertrophy, and inflammation in osteoarthritis to offer a potential therapeutic strategy.
Pig Liver Esterase Hydrolysis of 2-Arachidonoglycerol Exacerbates PRRSV-Induced Inflammation via PI3K-Akt-NF-κB Pathway.
In situ-formed immunotherapeutic hydrogel containing sphingosine-1-phosphate for enhanced lung cancer immunotherapy.
SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα.
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Urate-lowering and renal-protective effects of sugarcane polyphenols in hyperuricemia: mechanisms and key components.
β-Nicotinamide mononucleotide protects against hypervirulent Klebsiella pneumoniae bloodstream infection and liver injury.
HMGB1/RAGE signaling mediates the activation of microglia and participates in depressive-like behaviors and cognitive deficits in rats after ischemia-reperfusion.
CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma.
Isorhamnetin protects against D-GalN/LPS-induced acute liver injury in mice through anti-oxidative stress, anti-inflammation, and anti-apoptosis.
TRIM31 triggers colorectal carcinogenesis and progression by maintaining YBX1 protein stability through ubiquitination modification.
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
Host factor Naf1 restricts HIV-1 infection of myeloid cells and compromises the capacity of dendritic cell to prime CD4(+) T cell.
The chemokine receptor type 5 inhibitor maraviroc alleviates sepsis-associated liver injury by regulating MAPK/NF-κB signaling.
CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway.
Crucial role of low molecular weight chondroitin sulfate from hybrid sturgeon cartilage in osteoarthritis improvement: Focusing on apoptosis, systemic inflammation, and intestinal flora.
NLRC3 affects the development of psoriasis by modulating the NF-κB signaling pathway mediated inflammatory response through its interaction with TRAF6.
Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway.
RNF144A inhibits autophagy by targeting BECN1 for degradation during L. monocytogenes infection.
Neuroimmune regulation of IFITM3 via γ-secretase in astrocytes during cerebral ischemia-reperfusion.
Sulfonation of Capsaicin by sulfotransferases produces an anti-inflammatory metabolite with NF-κB pathway modulatory activity.
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
Sanzi Yangqin Decoction improved acute lung injury by regulating the TLR2-mediated NF-κB/NLRP3 signaling pathway and inhibiting the activation of NLRP3 inflammasome.
An Anti-CD147 Antibody-Drug Conjugate Mehozumab-DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey.
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis.
The Role and Mechanism of TRIM13 Regulation of TRAF6 Ubiquitination in the Synergy of Inflammatory Responses and Neurotoxicity Induced by METH and HIV- 1 Tat Protein in Astrocytes.
Berberine Alleviates 1-Methyl-3-Nitro-1-Nitrosoguanidine- Induced Chronic Atrophic Gastritis in Rats.
Alleviation of obesity cardiomyopathy by Fisetin through the inhibition of NF-κB/MAPK signaling.
A Visible-Light Photocatalysis/Hydrolysis Hydrogen-Generating Nanoplatform for Dynamic Inflammation Management via Immune Metabolism Orchestration during Wound Repair.
Unveiling the multifaceted benefits of Simiao Pill in ulcerative colitis: Integrative analysis of signaling pathways, gut microbiota, and lipid metabolism.
Regulation of monocyte polarization through nuclear factor Kappa B /inhibitor of Kappa B Alpha pathway by Cuscuta chinensis Lam. In postmenopausal osteoporosis.
Bioinformatics analysis and experimental validation of potential targets and pathways in chronic kidney disease associated with renal fibrosis.
Lactobacillus murinus ZNL-13 Modulates Intestinal Barrier Damage and Gut Microbiota in Cyclophosphamide-Induced Immunosuppressed Mice.
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Exercise antagonizes cadmium-caused liver and intestinal injury in mice via Nrf2 and TLR2/NF-κB signalling pathway.
DNA Methylation Mediates the Transcription of STAT4 to Regulate KISS1 During Follicular Development.
Prognostic Significance of Nuclear Factor Kappa B (p65) among Breast Cancer Patients in Cape Coast Teaching Hospital.
DNMT3A transcriptionally downregulated by KLF5 alleviates LPS-induced inflammatory response and promotes osteogenic differentiation in hPDLSCs.
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease.
The VP1 Protein of Porcine Teschovirus Inhibits the Innate Immune Response to Viral Infection by Blocking MDA5 Activation.
Identification of a Novel NLRP12 Frameshift Mutation (Val730Glyfs(∗)41) by Whole-Exome Sequencing in Patients with Crohn's Disease.
RETRACTED: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway.
miR-328-3p targets TLR2 to ameliorate oxygen-glucose deprivation injury and neutrophil extracellular trap formation in HUVECs via inhibition of the NF-κB signaling pathway.
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Unexpected Inhibitory Role of Silica Nanoparticles on Lung Cancer Development by Promoting M1 Polarization of Macrophages.
Reduced Proliferative Capacity and Defense against Staphylococcus aureus in Human Nasal Mucosal Epithelium Lacking ZNF365.
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Study on the Underlying Mechanism of Yinhua Gout Granules in the Treatment of Gouty Arthritis by Integrating Transcriptomics and Network Pharmacology.
Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats.
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing and Machine Learning.
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Ephedra sinica polysaccharide regulate the anti-inflammatory immunity of intestinal microecology and bacterial metabolites in rheumatoid arthritis.
Research on the metabolic regulation mechanism of Yangyin Qingfei decoction plus in severe pneumonia caused by Mycoplasma pneumoniae in mice.
Material basis and molecular mechanisms of Chaihuang Qingyi Huoxue Granule in the treatment of acute pancreatitis based on network pharmacology and molecular docking-based strategy.
Shikonin Exerts an Antileukemia Effect against FLT3-ITD Mutated Acute Myeloid Leukemia Cells via Targeting FLT3 and Its Downstream Pathways.
Integrating machine learning algorithms and single-cell analysis to identify gut microbiota-related macrophage biomarkers in atherosclerotic plaques.
Inhibitory effect of hydroxychloroquine on glucocorticoid-induced osteoporosis in lupus therapy.
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
Overexpression of the Mas1 gene mitigated LPS-induced inflammatory injury in mammary epithelial cells by inhibiting the NF-κB/MAPKs signaling pathways.
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples.
Reprogramming exosomes for immunity-remodeled photodynamic therapy against non-small cell lung cancer.
Prunus persica (L.) Batsch blossom soluble dietary fiber synergia polyphenol improving loperamide-induced constipation in mice via regulating stem cell factor/C-kit, NF-κB signaling pathway and gut microbiota.
Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned piglets.
Rice bran active peptide (RBAP) inhibited macrophage differentiation to foam cell and atherosclerosis in mice via regulating cholesterol efflux.
Polygala tenuifolia willd. Extract alleviates LPS-induced acute lung injury in rats via TLR4/NF-κB pathway and NLRP3 inflammasome suppression.
Catalpol alleviates heat stroke-induced liver injury in mice by downregulating the JAK/STAT signaling pathway.
Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
Fatty acids promote M1 polarization of monocyte-derived macrophages in healthy or ketotic dairy cows and a bovine macrophage cell line by impairing mTOR-mediated autophagy.
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome.
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Palmatine ameliorates N-methyl-N'-nitrosoguanidine-induced chronic atrophic gastritis through the STAT1/CXCL10 axis.
MLN4924 alleviates autoimmune myocarditis by promoting Act1 degradation and blocking Act1-mediated mRNA stability.
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Inhibiting Soluble Epoxide Hydrolase Suppresses NF-κB p65 Signaling and Reduces CXCL10 Expression as a Potential Therapeutic Target in Hashimoto's Thyroiditis.
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Hydrogen combined with tetrandrine attenuates silica-induced pulmonary fibrosis via suppressing NF-kappaB/NLRP3 signaling pathway-mediated epithelial mesenchymal transition and inflammation.
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Dietary Zn proteinate with moderate chelation strength alleviates heat stress-induced intestinal barrier function damage by promoting expression of tight junction proteins via the A20/NF-κB p65/MMP-2 pathway in the jejunum of broilers.
Role of NF-κB signaling pathway in H(2)O(2)-induced oxidative stress of hiPSCs.
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
EtROP38 suppresses apoptosis of host cells infected with Eimeria tenella by inhibition of the p38MAPK pathway.
2,5-Dihydroxyacetophenone attenuates acute kidney injury induced by intra-abdominal infection in rats.
Structure characterization and immunological activity of capsular polysaccharide from live and heat-killed Lacticaseibacillus paracasei 6235.
A preliminary study of T-2 toxin that cause liver injury in rats via the NF-kB and NLRP3-mediated pyroptosis pathway.
A novel HOIP frameshift variant alleviates NF-kappaB signalling and sensitizes cells to TNF-induced death.
Lipocalin-2-mediated intestinal epithelial cells pyroptosis via NF-κB/NLRP3/GSDMD signaling axis adversely affects inflammation in colitis.
Schisandra chinensis lignans regulate and cooperate with endogenous cannabinoid systems to ameliorate intestinal barrier injury associated with depression.
Proteomics reveals the pharmacological mechanism of flavonoids from Astragali Complanati Semen in preventing chronic liver injury.
Pathogen-Mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Immunization.
Dehydrocostus Lactone Ameliorates LPS-Induced Acute Lung Injury by Inhibiting PFKFB3-Mediated Glycolysis.
Sirtuin 5-Mediated Desuccinylation of ALDH2 Alleviates Mitochondrial Oxidative Stress Following Acetaminophen-Induced Acute Liver Injury.
WNT2B high‑expressed fibroblasts induce the fibrosis of IBD by promoting NK cells secreting IL-33.
Orally Administered Ginkgolide C Alleviates MPTP-Induced Neurodegeneration by Suppressing Neuroinflammation and Oxidative Stress through Microbiota-Gut-Brain Axis in Mice.
STING Agonist Delivered by Neutrophil Membrane-Coated Gold Nanoparticles Exerts Synergistic Tumor Inhibition with Radiotherapy.
Transcriptomic analysis reveals the critical role of chemokine signaling in the anti-atherosclerosis effect of Xuefu Zhuyu decoction.
Isomalto-Oligosaccharide Potentiates Alleviating Effects of Intermittent Fasting on Obesity-Related Cognitive Impairment during Weight Loss and the Rebound Weight Gain.
Upregulation of Cullin1 neddylation promotes glycolysis and M1 polarization of macrophage via NF-κB p65 pathway in sepsis.
Schisandrin B restores M1/M2 balance through miR-124 in lipopolysaccharide-induced BV2 cells.
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Sequential system based on ferritin delivery system and cell therapy for modulating the pathological microenvironment and promoting recovery.
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
MRG15 aggravates sepsis-related liver injury by promoting PCSK9 synthesis and secretion.
Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling.
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Effects of Nitric Oxide on Bladder Detrusor Overactivity through the NRF2 and HIF-1α Pathways: A Rat Model Induced by Metabolic Syndrome and Ovarian Hormone Deficiency.
Exosomal let-7b-5p deriving from parietal epithelial cells attenuate renal fibrosis through suppression of TGFβR1 and ARID3a in obstructive kidney disease.
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
Tas2R143 regulates the expression of the Blood-Testis Barrier tight junction protein in TM4 cells through the NF-κB signaling pathway.
Sulforaphane Improves Liver Metabolism and Gut Microbiota in Circadian Rhythm Disorder Mice Models Fed With High-Fat Diets.
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis.
Placental ischemia-upregulated angiotensin II type 1 receptor in hypothalamic paraventricular nucleus contributes to hypertension in rat.
Effects of daphnetin on the mechanism of epithelial-mesenchymal transition induced by HMGB1 in human lung adenocarcinoma cells (A549 cell line).
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
USP9X-enriched MSC-sEV inhibits LSEC angiogenesis in MASH mice by downregulating the IκBα/NF-κB/Ang-2 pathway.
Increased adrenal steroidogenesis and suppressed corticosteroid responsiveness in critical COVID-19.
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Ginsenoside Rk3 Treats Corneal Injury Through the HMGB1/TLR4/NF-κB Pathway.
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
The methyltransferase METTL3 regulates endothelial cell proliferation and inflammation via m(6)A RNA methylation-mediated TRAF1 expression.
Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein.
LncRNA DDX11-AS1 promotes breast cancer progression by targeting the miR-30c-5p/MTDH axis.
The Effect of Meloxicam on Inflammatory Response and Oxidative Stress Induced by Klebsiella pneumoniae in Bovine Mammary Epithelial Cells.
Berbamine Promotes the Repair of Lower Limb Muscle Damage in Chronic Limb-Threatening Ischemia by Inhibiting Local Inflammation and NF-κB Nuclear Translocation.
Effect of Tricin on cardiomyocyte damage caused by diabetic cardiomyopathy (DCM).
Probiotics alleviate chronic ethanol exposure-induced anxiety-like behavior and hippocampal neuroinflammation in male mice through gut microbiota-derived extracellular vesicles.
miRNA-431-5p enriched in EVs derived from IFN-β stimulated MSCs potently inhibited ZIKV through CD95 downregulation.
LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Vitamin C ameliorates D-galactose-induced senescence in HEI-OC1 cells by inhibiting the ROS/NF-κB pathway.
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Distinct pathways utilized by METTL3 to regulate antiviral innate immune response.
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade.
PFOS impairs cardiac function and energy metabolism under high-fat diet: Insights into role of circulating macrophage emphasized by exposure distribution.
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
IL1RAP Exacerbates Sepsis-Induced Pulmonary and Spleen Injury Through Regulating CD4(+) T Lymphocyte Differentiation.
iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation.
Administration of USP7 inhibitor p22077 alleviates Angiotensin II (Ang II)-induced atrial fibrillation in Mice.
Curcumin attenuates aflatoxin B1-induced ileum injury in ducks by inhibiting NLRP3 inflammasome and regulating TLR4/NF-κB signaling pathway.
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway.
Protective effects of sodium humate and its zinc and selenium chelate on the oxidative stress, inflammatory, and intestinal barrier damage of Salmonella Typhimurium-challenged broiler chickens.
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
The haemagglutinin-neuraminidase protein of velogenic Newcastle disease virus enhances viral infection through NF-κB-mediated programmed cell death.
Dietary Fiber-Derived Butyrate Alleviates Piglet Weaning Stress by Modulating the TLR4/MyD88/NF-κB Pathway.
Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis.
HuR promotes triglyceride synthesis and intestinal fat absorption.
Readily Available Oral Prebiotic Protein Reactive Oxygen Species Nanoscavengers for Synergistic Therapy of Inflammation and Fibrosis in Inflammatory Bowel Disease.
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
Mechanistic study of acupuncture on the pterygopalatine ganglion to improve allergic rhinitis: analysis of multi-target effects based on bioinformatics/network topology strategie.
Glycyrrhizic Acid Alleviates Semen Strychni-Induced Neurotoxicity Through the Inhibition of HMGB1 Phosphorylation and Inflammatory Responses.
Inhibition of Nogo-B reduces the progression of pancreatic cancer by regulation NF-κB/GLUT1 and SREBP1 pathways.
Oxidized DJ-1 activates the p-IKK/NF-κB/Beclin1 pathway by binding PTEN to induce autophagy and exacerbate myocardial ischemia-reperfusion injury.
The role of FGF-21 in promoting diabetic wound healing by modulating high glucose-induced inflammation.
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 in flammasome, and NFκB activity.
Mammalian STE20-like kinase 1 inhibits synoviocytes activation in rheumatoid arthritis through mitochondrial dysfunction mediated by SIRT3/mTOR axis.
Comparison between hangeshashinto and dexamethasone for IL-1α and β-defensin 1 production by human oral keratinocytes.
Tetramethylpyrazine inhibits the inflammatory response by downregulating the TNFR1/IκB-α/NF-κB p65 pathway after spinal cord injury.
Amelioration of obesity and inflammation by polysaccharide from unripe fruits of raspberry via gut microbiota regulation.
VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds.
Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway.
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.
OR11H1 Missense Variant Confers the Susceptibility to Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression.
Caffeic acid-grafted chitooligosaccharides downregulate MAPK and NF-kB in RAW264.7 cells.
MSR405: Inhibiting Neuroinflammation after Spinal Cord Injury in Rats.
Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway.
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Baiheqingjin formula reduces inflammation in mice with asthma by inhibiting the PI3K/AKT/NF-κb signaling pathway.
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
Study on the effect and mechanism of Zhenzhu Tongluo pills in treating diabetic peripheral neuropathy injury.
Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.
SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1.
BMSC-derived exosomes regulate the Treg/Th17 balance through the miR-21-5p/TLR4/MyD88/NF-κB pathway to alleviate dry eye symptoms in mice.
Neutrophil Extracellular Traps Induce Pyroptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the NF-κB/Caspase 3/GSDME Pathway.
Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer.
The hsa_circ_0082152 maintains NF-κB mRNA stability by binding to MTDH to promote anti-tuberculosis drug-induced liver injury.
Platelet-rich plasma alleviates knee arthritis in rats by inhibiting p65.
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Calmodulin Contributes to Lipolysis and Inflammatory Responses in Clinical Ketosis Cows through the TLR4/IKK/NF-κB Pathway.
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Sorcin Inhibits Mitochondrial Apoptosis by Interacting with STAT3 via NF-κB Pathway.
The effect of miR‑155‑5p on long‑term memory of sleep‑deprived mice through the BDNF/NF‑κB pathway.
The Combination of Bacillus natto JLCC513 and Ginseng Soluble Dietary Fiber Attenuates Ulcerative Colitis by Modulating the LPS/TLR4/NF-κB Pathway and Gut Microbiota.
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis.
Gold Nanoparticle Delivery of Glut1 SiRNA Facilitates Glucose Starvation Therapy in Lung Cancer.
Cathelicidin-BF regulates the AMPK/SIRT1/NF-κB pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie.
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase.
Asprosin promotes vascular inflammation via TLR4-NFκB-mediated NLRP3 inflammasome activation in hypertension.
Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study.
YTHDC1 inhibits autophagy-dependent NF-κB signaling by stabilizing Beclin1 mRNA in macrophages.
Transmissible gastroenteritis virus induces inflammatory responses via RIG-I/NF-κB/HIF-1α/glycolysis axis in intestinal organoids and in vivo.
An Isofibrous Diet with Fiber Konjac Glucomannan Ameliorates Salmonella typhimurium-Induced Colonic Injury by Regulating TLR2-NF-κB Signaling and Intestinal Microbiota in Mice.
Tissue-resident C1q + macrophages exert anti-aging potential through the Sirt1 pathway.
Lipoxin A(4) ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through activation of the ESR2/LPAR3/Nrf2 axis in synovial fibroblast-like synoviocytes.
20-hydroxyecdysone suppresses bladder cancer progression via inhibiting USP21: A mechanism associated with deubiquitination and degradation of p65.
Chitosan-modified dihydromyricetin liposomes promote the repair of liver injury in mice suffering from diabetes mellitus.
GRP78 Downregulation in Keratinocytes Promotes Skin Inflammation through the Recruitment and Activation of CCR6(+) IL-17A-Producing γδ T Cells.
Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway.
Ethanolic extract of Arctium lappa leaves alleviates cerebral ischemia reperfusion-induced inflammatory injury via HDAC9-mediated NF-κB pathway.
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention.
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned Piglets.
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury.
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
GM1 Ameliorates Neuronal Injury in Rats after Cerebral Ischemia and Reperfusion: Potential Contribution of Effects on SPTBN1-mediated Signaling.
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
Weissella paramesenteroides NRIC1542 inhibits dextran sodium sulfate-induced colitis in mice through regulating gut microbiota and SIRT1/NF-κB signaling pathway.
The protective effects of aqueous extract of Schisandra sphenanthera against alcoholic liver disease partly through the PI3K-AKT-IKK signaling pathway.
Lysophosphatidylcholine trigger myocardial injury in diabetic cardiomyopathy via the TLR4/ZNF480/AP-1/NF-kB pathway.
Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis.
ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway.
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Lixisenatide ameliorated lipopolysaccharide (LPS)-induced expression of mucin and inflammation in bronchial epithelial cells.
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells.
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Allograft inflammatory factor-1 enhances inflammation and oxidative stress via the NF-κB pathway of bladder urothelium in diabetic rat model.
Protective effects of sodium humate on the intestinal barrier damage of Salmonella Typhimurium-challenged broilers.
Selection and Characterization of a DNA Aptamer Recognizing High Mobility Group Box 1 Protein (HMGB1) and Enhancing Its Pro-inflammatory Activity.
Grape seed-derived procyanidins decreases neuropathic pain and nerve regeneration by suppression of toll-like receptor 4-myeloid differentiation factor-88 signaling.
Gut microbiota regulates host melatonin production through epithelial cell MyD88.
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma.
Baicalin exerts neuroprotective actions by regulating the Nrf2-NLRP3 axis in toxin-induced models of Parkinson's disease.
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Free heme induces neuroinflammation and cognitive impairment by microglial activation via the TLR4/MyD88/NF-κB signaling pathway.
Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice.
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway.
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
Lactate dehydrogenase A promotes nasopharyngeal carcinoma progression through the TAK1/NF-κB Axis.
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
The protective effect of Schisandra chinensis (Turcz.) Baill. polysaccharide on DSS-induced ulcerative colitis in mice via the modulation of gut microbiota and inhibition of NF-κB activation.
An exploration of the effect of Chinese herbal compound on the occurrence and development of large intestine cancer and intestinal flora.
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation.
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Yang-Xin-Shu-Mai granule alleviates atherosclerosis by regulating macrophage polarization via the TLR9/MyD88/NF-κB signaling pathway.
Partial Replacement of NaCl with KCl in Cooked Meat Could Reduce the Liver Damage Through Renin-Angiotensin System in Mice.
Exosomes Derived from Quercetin-Treated Bone Marrow Derived Mesenchymal Stem Cells Inhibit the Progression of Osteoarthritis Through Delivering miR-124-3p to Chondrocytes.
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Oral administration of punicalagin attenuates imiquimod-induced psoriasis by reducing ROS generation and inflammation via MAPK/ERK and NF-κB signaling pathways.
Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines.
In vitro and in vivo immunomodulatory activity of acetylated polysaccharides from Cyclocarya paliurus leaves.
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Attenuation of pro-tumorigenic senescent secretory phenotype by StN, a novel derivative of stevioside, potentiates its inhibitory activity on hepatocellular carcinoma.
Isoflavones isolated from chickpea sprouts alleviate ovariectomy-induced osteoporosis in rats by dual regulation of bone remodeling.
Exploration of costunolide derivatives as potential anti-inflammatory agents for topical treatment of atopic dermatitis by inhibiting MAPK/NF-κB pathways.
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Palmatine ameliorated lipopolysaccharide-induced sepsis-associated encephalopathy mice by regulating the microbiota-gut-brain axis.
Atypical inflammatory kinase IKBKE phosphorylates and inactivates FoxA1 to promote liver tumorigenesis.
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Osteostatin Mitigates Gouty Arthritis through the Inhibition of Caspase-1 Activation and Upregulation of Nrf2 Expression.
Mitochondrial reactive oxygen species initiate gasdermin D-mediated pyroptosis and contribute to paraquat-induced nephrotoxicity.
Assessing the effects of tempol on renal fibrosis, inflammation, and oxidative stress in a high-salt diet combined with 5/6 nephrectomy rat model: utilizing oxidized albumin as a biomarker.
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Knockdown of DNMT1 Induces SLCO3A1 to Promote Follicular Growth by Enhancing the Proliferation of Granulosa Cells in Mammals.
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
The Pea Oligosaccharides Could Stimulate the In Vitro Proliferation of Beneficial Bacteria and Enhance Anti-Inflammatory Effects via the NF-κB Pathway.
Dendrobium officinale Polysaccharides as a Natural Functional Component for Acetic-Acid-Induced Gastric Ulcers in Rats.
S100A4/NF-κB axis mediates the anticancer effect of epigallocatechin-3-gallate in platinum-resistant ovarian cancer.
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.
Sasanquasaponin from Camellia oleifera Abel Exerts an Anti-Inflammatory Effect in RAW 264.7 Cells via Inhibition of the NF-κB/MAPK Signaling Pathways.
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Runx2 Suppresses Astrocyte Activation and Astroglial Scar Formation After Spinal Cord Injury in Mice.
Pseudorabies virus UL13 primes inflammatory response through downregulating heat shock factor 1.
Hypothermic oxygenated perfusion inhibits CLIP1-mediated TIRAP ubiquitination via TFPI2 to reduce ischemia‒reperfusion injury of the fatty liver.
G protein-coupled receptor kinase 2 as a novel therapeutic target for gland fibrosis of Sjögren's syndrome.
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Zuyangping formula promotes skin wound healing in diabetic rats.
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
Chitosan-based self-healing thermosensitive hydrogel loaded with siHMGB1 for treatment of rheumatoid arthritis via macrophage repolarization.
Anti-inflammatory activity and underlying mechanism against sepsis-induced acute lung injury of a low-molecular-weight polysaccharide from the root of Stemona tuberosa Lour.
Pharmacological Network Analysis of the Functions and Mechanism of Quercetin From Jisuikang (JSK) in Spinal Cord Injury (SCI).
Paquinimod attenuates retinal injuries by suppressing the S100A9/TLR4 signaling in an experimental model of diabetic retinopathy.
Intestinal barrier, immunity and gut microbiota-based protective effects of Lactococcus lactis HF08 and its postbiotic derivative on aging and aging colitis mice.
Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers.
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
New benzophenone analogs from Nigrospora sphaerica and their inhibitory activity against PD-1/PD-L1 interactions.
Biologically active franchetine-type diterpenoid alkaloids: Isolation, synthesis, anti-inflammatory, agalgesic activities, and molecular docking.
Pterosin B improves cognitive dysfunction by promoting microglia M1/M2 polarization through inhibiting Klf5/Parp14 pathway.
Cardioprotective effects of polydatin against myocardial injury in HFD/stz and high glucose-induced diabetes via a Caveolin 1-dependent mechanism.
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling.
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
Fucoidan from Laminaria japonica protects renal tubular epithelial cells from uric acid induced NLRP3-mediated pyroptosis through inhibition of NF-κB pathway.
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Toralactone alleviates cisplatin-induced acute kidney injury by modulating the gut microbiota-renal axis.
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Intranasal administration of Clostridium butyricum and its derived extracellular vesicles alleviate LPS-induced acute lung injury.
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Dual rectification of metabolism abnormality in pancreatic cancer by a programmed nanomedicine.
Neutrophil extracellular traps in rheumatoid arthritis: Activating fibroblast-like synoviocytes via ATP citrate lyase.
Allosteric inhibition of the tyrosine phosphatase SHP2 enhances the anti-tumor immunity of interferon α through induction of caspase-1-mediated pyroptosis in renal cancer.
Colorectal cancer cells establish metabolic reprogramming with cancer-associated fibroblasts (CAFs) through lactate shuttle to enhance invasion, migration, and angiogenesis.
Nppb contributes to Sepsis-Induced myocardial injury by regulating Senescence-Related genes.
Preventive effects of matrine on LPS-induced inflammation in RAW 264.7 cells and intestinal damage in mice through the TLR4/NF-κB/MAPK pathway.
Corilagin inhibits human cytomegalovirus infection and replication via activating the cGAS-STING signaling pathway in vitro and in vivo.
SHP-1 alleviates acute liver injury caused by Escherichia coli sepsis through negatively regulating the canonical and non-canonical NFκB signaling pathways.
Colorectal cancer cell-derived exosomal miRNA-372-5p induces immune escape from colorectal cancer via PTEN/AKT/NF-κB/PD-L1 pathway.
Chlorogenic acid alleviates IPEC-J2 pyroptosis induced by deoxynivalenol by inhibiting activation of the NF-κB/NLRP3/caspase-1 pathway.
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
EZH2 elicits CD8(+) T-cell desert in esophageal squamous cell carcinoma via suppressing CXCL9 and dendritic cells.
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
HPV11 targeting KDM4A regulates the polarization of macrophage M(1) and promotes the development of nasal inverted papilloma.
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Soyasaponin Bb/Gelatin-Methacryloyl Hydrogel for Cartilage Inflammation Inhibition.
Inflammatory mediator contributes to leptin resistance and obesity in craniopharyngioma.
Alantolactone improves cognitive impairment in rats with Porphyromonas gingivalis infection by inhibiting neuroinflammation, oxidative stress, and reducing Aβ levels.
NLRP3 blockade by MCC950 suppressed osteoclastogenesis via NF-κB/c-Fos/NFATc1 signal pathway and alleviated bone loss in diabetes mellitus.
Pseudorabies virus VHS protein abrogates interferon responses by blocking NF-κB and IRF3 nuclear translocation.
Silicone dressing combined with topical oxygen therapy alleviates incontinence-associated dermatitis via NF-κB p65/STAT1 signaling pathway.
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
M2 macrophages promote PD-L1 expression in triple-negative breast cancer via secreting CXCL1.
A p38 MAP kinase inhibitor suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss through the inhibition of bone turnover.
MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling.
Glycerol monolaurate regulates apoptosis and inflammation by suppressing lipopolysaccharide-induced ROS production and NF-κB activation in avian macrophages.
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
Dihydromyricetin Nanoparticles Alleviate Lipopolysaccharide-Induced Acute Kidney Injury by Decreasing Inflammation and Cell Apoptosis via the TLR4/NF-κB Pathway.
Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte.
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells.
Excitatory amino acid transporter supports inflammatory macrophage responses.
Development of new dehydrocostuslactone derivatives for treatment of atopic dermatitis via inhibition of the NF-κB signaling pathway.
Electroacupuncture Improving Intestinal Barrier Function in Rats with Irritable Bowel Syndrome Through Regulating Aquaporins.
Sulforaphane inhibits the migration and invasion of BPDE-induced lung adenocarcinoma cells by regulating NLRP12.
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Ganoderic acids alleviate atherosclerosis by inhibiting macrophage M1 polarization via TLR4/MyD88/NF-κB signaling pathway.
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response.
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
M2 macrophage‑derived exosomes alleviate KCa3.1 channel expression in rapidly paced HL‑1 myocytes via the NF‑κB (p65)/STAT3 signaling pathway.
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Purification, structural characterization, and immunomodulatory activity of two polysaccharides from Portulaca oleracea L.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.
Nucleoporin93 limits Yap activity to prevent endothelial cell senescence.
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats.
Osthole Activates the Cholinergic Anti-Inflammatory Pathway via α7nAChR Upregulation to Alleviate Inflammatory Responses.
Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Single-cell transcriptomics reveals the ameliorative effect of rosmarinic acid on diabetic nephropathy-induced kidney injury by modulating oxidative stress and inflammation.
NF-κB affected the serum levels of TNF-α and IL-1β via activation of the MAPK/NF-κB signaling pathway in rat model of acute pulmonary microthromboembolism.
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro.
Mycobacterium tuberculosis PE_PGRS38 Enhances Intracellular Survival of Mycobacteria by Inhibiting TLR4/NF-κB-Dependent Inflammation and Apoptosis of the Host.
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
Gypenoside XLIX alleviates acute liver injury: Emphasis on NF-κB/PPAR-α/NLRP3 pathways.
6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway.
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Dietary Galacto-oligosaccharides Ameliorate Atopic Dermatitis-like Skin Inflammation and Behavioral Deficits by Modulating Gut Microbiota-Brain-Skin Axis.
Protective role of forsythoside B in Kawasaki disease-induced cardiac injury: Inhibition of pyroptosis via the SIRT1-NF-κB-p65 signaling pathway.
Phthalate drives splenic inflammatory response via activating HSP60/TLR4/NLRP3 signaling axis-dependent pyroptosis.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
Herpetrione, a New Type of PPARα Ligand as a Therapeutic Strategy Against Nonalcoholic Steatohepatitis.
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Triamcinolone acetonide induces the autophagy of Ag85B-treated WI-38 cells via SIRT1/FOXO3 pathway.
Protease-Activated Receptor-2 and Phospholipid Metabolism Analysis in Hyperuricemia-Induced Renal Injury.
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
Rapamycin suppresses inflammation and increases the interaction between p65 and IκBα in rapamycin-induced fatty livers.
Effect of matrine in MAC-T cells and their transcriptome analysis: A basic study.
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Ginseng Saponin Rb1 Attenuates Cigarette Smoke Exposure-Induced Inflammation, Apoptosis and Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Signaling Pathways.
α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously.
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
A novel large animal model of posttraumatic osteoarthritis induced by inflammation with mechanical stability.
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
Ethyl acetate extract of Terminalia chebula alleviates DSS-induced ulcerative colitis in C57BL/6 mice.
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A.
Endothelial exosomes work as a functional mediator to activate macrophages.
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
The delta subunit of the GABA(A) receptor is necessary for the GPT2-promoted breast cancer metastasis.
Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancer.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization.
Donor-Matched Peripheral Blood-Derived Mesenchymal Stem Cells Combined With Platelet-Rich Plasma Synergistically Ameliorate Surgery-Induced Osteoarthritis in Rabbits: An In Vitro and In Vivo Study.
AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression.
ANRIL regulating the secretion of Muc5ac induced by atmospheric PM(2.5) via NF-κB pathway in Beas-2B cells.
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
The Chinese medicine Xin-tong-tai granule protects atherosclerosis by regulating oxidative stress through NOX/ROS/NF-κB signal pathway.
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
Angiopoietin-2 Promotes Mechanical Stress-induced Extracellular Matrix Degradation in Annulus Fibrosus Via the HIF-1α/NF-κB Signaling Pathway.
IL-38 suppresses macrophage M1 polarization to ameliorate synovial inflammation in the TMJ via GLUT-1 inhibition.
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Degenerated nucleus pulposus cells derived exosome carrying miR-27a-3p aggravates intervertebral disc degeneration by inducing M1 polarization of macrophages.
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
LINC00460 promotes angiogenesis by enhancing NF-κB-mediated VEGFA expression in cervical cancer cells.
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice.
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
The Effects of an Osteoarthritic Joint Environment on ACL Damage and Degeneration: A Yucatan Miniature Pig Model.
Shiwei Qingwen decoction regulates TLR4/NF-κB signaling pathway and NLRP3 inflammasome to reduce inflammatory response in lipopolysaccharide-induced acute lung injury.
Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice.
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
NR2C2 of macrophages promotes inflammation via NF-κB in LPS-induced orchitis in mice.
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
SALL1 promotes proliferation and metastasis and activates phosphorylation of p65 and JUN in colorectal cancer cells.
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
An in vitro and in vivo study: Valencene protects cartilage and alleviates the progression of osteoarthritis by anti-oxidative stress and anti-inflammatory effects.
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10.
Epithelial-specific deletion of FAM20A leads to short root defects.
Scutellarin attenuates oxidative stress and neuroinflammation in cerebral ischemia/reperfusion injury through PI3K/Akt-mediated Nrf2 signaling pathways.
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.
Arenobufagin increases the sensitivity of gastric cancer to cisplatin via alkaliptosis.
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Nuciferine protects against lipopolysaccharide-induced endometritis via inhibiting ferroptosis and modulating AMPKα/mTOR/HIF-1α signaling axis.
Pyroptosis of chondrocytes activated by synovial inflammation accelerates TMJ osteoarthritis cartilage degeneration via ROS/NLRP3 signaling.
Rabdosichuanin C inhibits productions of pro-inflammatory mediators regulated by NF-κB signaling in LPS-stimulated RAW264.7 cells.
A Dihydroartemisinin-Loaded Nanoreactor Motivates Anti-Cancer Immunotherapy by Synergy-Induced Ferroptosis to Activate Cgas/STING for Reprogramming of Macrophage.
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation.
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells.
Network Analysis and Experimental Verification of the Mechanisms of Hydroxysafflor Yellow A in Ischemic Stroke Following Atherosclerosis.
Gentiana Scabra Bge Extract (GSE) Protects Against Alcoholic Liver Disease by Regulating the TLR4/NF-κB Pathway in Mice.
Salidroside Ameliorates Furan-Induced Testicular Inflammation in Relation to the Gut-Testis Axis and Intestinal Apoptosis.
Artemether Attenuates Gut Barrier Dysfunction and Intestinal Flora Imbalance in High-Fat and High-Fructose Diet-Fed Mice.
Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence.
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Fluoride-induced osteoporosis via interfering with the RANKL/RANK/OPG pathway in ovariectomized rats: Oophorectomy shifted skeletal fluorosis from osteosclerosis to osteoporosis.
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma-aminobutyric acid (GABA)-ergic pathway and PI3K/AKT/NF-κB pathway.
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer.
Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65.
Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats.
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.
Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis.
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
The potential role of the pseudobranch of molly fish (Poecilia sphenops) in immunity and cell regeneration.
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Dahuang Zhechong pill attenuates hepatic sinusoidal capillarization in liver cirrhosis and hepatocellular carcinoma rat model via the MK/integrin signaling pathway.
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
FXYD3 enhances IL-17A signaling to promote psoriasis by competitively binding TRAF3 in keratinocytes.
Paeoniflorin alleviates inflammation in bovine mammary epithelial cells induced by Staphylococcus haemolyticus through TLR2/NF-κB signaling pathways.
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Meloxicam inhibited oxidative stress and inflammatory response of LPS-stimulated bovine endometrial epithelial cells through Nrf2 and NF-κB pathways.
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy.
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Improvement of vaginal probiotics Lactobacillus crispatus on intrauterine adhesion in mice model and in clinical practice.
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
LINC01393, a Novel Long Non-Coding RNA, Promotes the Cell Proliferation, Migration and Invasion through MiR-128-3p/NUSAP1 Axis in Glioblastoma.
Selective Targeting of Class I HDAC Reduces Microglial Inflammation in the Entorhinal Cortex of Young APP/PS1 Mice.
Hypoxia-Induced Kidney Injury in Newborn Rats.
Novel long non-coding RNAs associated with inflammation and macrophage activation in human.
PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway.
Remote preconditioning combined with nebulized budesonide alleviate lipopolysaccharide induced acute lung injury via regulating HO-1 and NF-κB in rats.
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
Serum amyloid A and interleukin -1β facilitate LDL transcytosis across endothelial cells and atherosclerosis via NF-κB/caveolin-1/cavin-1 pathway.
Baicalin ameliorates high fat diet-induced nonalcoholic fatty liver disease in mice via adenosine monophosphate-activated protein kinase-mediated regulation of SREBP1/Nrf2/NF-κB signaling pathways.
Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Hepatocyte-derived extracellular vesicles miR-122-5p promotes hepatic ischemia reperfusion injury by regulating Kupffer cell polarization.
Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice.
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments.
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain.
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
Dysregulation of MiR-199a/IL8 pathway in chronic Cr (VI)-induced tumor growth and angiogenesis.
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system.
Epstein-Barr Virus Envelope Glycoprotein gp110 Inhibits IKKi-Mediated Activation of NF-κB and Promotes the Degradation of β-Catenin.
SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy.
ATPIF1 alleviates oxygen glucose deprivation/reoxygenation-induced astrocyte injury in vitro: A rat model of ischemic brain injury.
Silicate ions as soluble form of bioactive ceramics alleviate aortic aneurysm and dissection.
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis.
Dimethyl fumarate possesses antiplatelet and antithrombotic properties.
Exenatide improves hypogonadism and attenuates inflammation in diabetic mice by modulating gut microbiota.
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Total saponins from Panax japonicus reduce inflammation in adipocytes through the miR155/SOCS1/NFκB signaling pathway.
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway.
Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats.
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation.
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer.
In vitro and in vivo effects of 3-indoleacetonitrile-A potential new broad-spectrum therapeutic agent for SARS-CoV-2 infection.
Diterpenoids with anti-inflammatory activity from Euphorbia wallichii.
Koumine ameliorates concanavalin A-induced autoimmune hepatitis in mice: involvement of the Nrf2, NF-κB pathways, and gut microbiota.
Structural and immunohistochemical analysis of the cellular compositions of the liver of molly fish (Poecilia sphenops), focusing on its immune role.
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2.
Microglial activation and over pruning involved in developmental epilepsy.
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways.
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Melatonin alleviates BDE-209-induced cognitive impairment and hippocampal neuroinflammation by modulating microglia polarization via SIRT1-mediated HMGB1/TLR4/NF-κB pathway.
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Trans-anethole exerts protective effects on lipopolysaccharide-induced acute jejunal inflammation of broilers via repressing NF-κB signaling pathway.
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury.
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway.
Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro.
DBDPE upregulates NOD-like receptor signaling to induce NLRP3 inflammasome-mediated HAECs pyroptosis.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Sulforaphane Ameliorates Nonalcoholic Fatty Liver Disease Induced by High-Fat and High-Fructose Diet via LPS/TLR4 in the Gut-Liver Axis.
Auricular Vagus Nerve Stimulation Improves Visceral Hypersensitivity and Gastric Motility and Depression-like Behaviors via Vago-Vagal Pathway in a Rat Model of Functional Dyspepsia.
Phenylalanine diminishes M1 macrophage inflammation.
Endogenous hydrogen sulfide inhibition suppresses tumor growth by promoting apoptosis and pyroptosis in esophageal cancer cells.
Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats.
The JAK/STAT/NF-κB signaling pathway can be regulated by rosemary essential oil, thereby providing a potential treatment for DNCB-induced in mice.
Catapol attenuates the aseptic inflammatory response to hepatic I/R injury in vivo and in vitro by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway via the microRNA-410-3p.
L-F001, a multifunctional fasudil-lipoic acid dimer, antagonizes hypoxic-ischemic brain damage by inhibiting the TLR4/MyD88 signaling pathway.
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
RNF144A promotes antiviral responses by modulating STING ubiquitination.
Piceatannol alleviates liver ischaemia/reperfusion injury by inhibiting TLR4/NF-κB/NLRP3 in hepatic macrophages.
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor.
Protective Effect of Ginsenoside CK against Autoimmune Hepatitis Induced by Concanavalin A.
Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway.
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Lipopolysaccharide-induced persistent inflammation ameliorates fat accumulation by promoting adipose browning in vitro and in vivo.
The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF‑κB in lung cancer.
PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway.
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
ROR1/STAT3 positive feedback loop facilitates cartilage degeneration in Osteoarthritis through activation of NF-κB signaling pathway.
Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.
AGEs promote atherosclerosis by increasing LDL transcytosis across endothelial cells via RAGE/NF-κB/Caveolin-1 pathway.
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling.
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Asprosin Exacerbates Endothelium Inflammation Induced by Hyperlipidemia Through Activating IKKβ-NF-κBp65 Pathway.
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota.
Combined treatment with glucosamine and chondroitin sulfate improves rheumatoid arthritis in rats by regulating the gut microbiota.
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Inhibition effect of 1-acetoxy-6α-(2-methylbutyryl)eriolanolide toward soluble epoxide hydrolase: Multispectral analysis, molecular dynamics simulation, biochemical, and in vitro cell-based studies.
Salvianolic Acid A Protects against Acetaminophen-Induced Hepatotoxicity via Regulation of the miR-485-3p/SIRT1 Pathway.
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis.
Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-κB Pathway.
Antibiotic Therapy and Vaginal Microbiota Transplantation Reduce Endometriosis Disease Progression in Female Mice via NF-κB Signaling Pathway.
Effect of Two Different Drug-Resistant Staphylococcus aureus Strains on the Physiological Properties of MAC-T Cells and Their Transcriptome Analysis.
Maternal nucleotide supplementation improves the intestinal morphology and immune function in lipopolysaccharide-challenged newborn piglets.
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.
Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade.
The Attenuation of Chronic Ulcerative Colitis by (R)-salbutamol in Repeated DSS-Induced Mice.
Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage.
Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways.
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice.
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Yanghe Pingchuan Granules Alleviate Airway Inflammation in Bronchial Asthma and Inhibit Pyroptosis by Blocking the TLR4/NF-κB/NRLP3 Signaling Pathway.
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Effects of Electroacupuncture on Gastrointestinal Motility Function, Pain, and Inflammation via Transient Receptor Potential Vanilloid 1 in a Rat Model after Colonic Anastomoses.
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
Curcumol Undermines SDF-1α/CXCR4/NF-κB Signaling Pathway to Suppress the Progression of Chronic Atrophic Gastritis (CAG) and Gastric Cancer.
Electroacupuncture Pretreatment Exhibits Lung Protective and Anti-Inflammation Effects in Lipopolysaccharide-Induced Acute Lung Injury via SIRT1-Dependent Pathways.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation of the Inflammatory Microenvironment.
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.
BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice.
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.
Aconiti lateralis radix praeparata total alkaloids exert anti-RA effects by regulating NF-κB and JAK/STAT signaling pathways and promoting apoptosis.
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments.
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage.
Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking.
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promoted Wound Healing by Regulating PI3K/AKT/mTOR and SIRT1/NF-κB Pathways.
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
MSC-ACE2 Ameliorates Streptococcus uberis-Induced Inflammatory Injury in Mammary Epithelial Cells by Upregulating the IL-10/STAT3/SOCS3 Pathway.
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
The Herb Pair Radix Rehmanniae and Cornus Officinalis Attenuated Testicular Damage in Mice With Diabetes Mellitus Through Butyric Acid/Glucagon-Like Peptide-1/Glucagon-Like Peptide-1 Receptor Pathway Mediated by Gut Microbiota.
Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control.
The Role of the Negative Regulation of Microglia-Mediated Neuroinflammation in Improving Emotional Behavior After Epileptic Seizures.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Plasma Exosomes Transfer miR-885-3p Targeting the AKT/NFκB Signaling Pathway to Improve the Sensitivity of Intravenous Glucocorticoid Therapy Against Graves Ophthalmopathy.
Cordyceps militaris Modulates Intestinal Barrier Function and Gut Microbiota in a Pig Model.
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Inhibitory effect of main phenolic acid components of Jacobaea cannabifolia (Less.) on inflammation caused by PM(2.5).
Dynamic changes in human THP-1-derived M1-to-M2 macrophage polarization during Thelazia callipaeda MIF induction.
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus.
Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway.
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
HIV-1 Tat Protein-Mediated Inflammatory Response Inhibits the Erythroid Hematopoietic Support Function of Bone Marrow Mesenchymal Stem Cells.
Endoplasmic reticulum-targeted inhibition of CYP2E1 with vitamin E nanoemulsions alleviates hepatocyte oxidative stress and reverses alcoholic liver disease.
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota.
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Lycopene-Loaded Bilosomes Ameliorate High-Fat Diet-Induced Chronic Nephritis in Mice through the TLR4/MyD88 Inflammatory Pathway.
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
Isosteviol sodium attenuates high fat/high cholesterol-induced myocardial dysfunction by regulating the Sirt1/AMPK pathway.
LncRNA-SUSAJ1 Activates the ER Stress Pathway Inhibiting JEV Proliferation by Promoting PK15 Cells Apoptosis.
Pseudogene CLEC4GP1 modulates trophoblast cell apoptosis and invasion via IL-15 inhibition.
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Ulinastatin Alleviates Rhabdomyolysis-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis via Inhibiting TLR4/NF-κB Signaling Pathway.
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Antihepatofibrotic effect of Guizhifuling pill on carbon tetrachloride-induced liver fibrosis in mice.
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
ALPK1 Accelerates the Pathogenesis of Osteoarthritis by Activating NLRP3 Signaling.
Curcumin antagonizes inflammation and autophagy induced by arsenic trioxide through immune protection in duck spleen.
mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification.
The anti-inflammatory effect of vasoactive peptides from soybean protein hydrolysates by mediating serum extracellular vesicles-derived miRNA-19b/CYLD/TRAF6 axis in the vascular microenvironment of SHRs.
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway.
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Endothelial RGS12 governs angiogenesis in inflammatory arthritis by controlling cilia formation and elongation via MYCBP2 signaling.
Aspirin Inhibits the Inflammatory Response of Protease-Activated Receptor 1 in Pregnancy Neutrophils: Implications for Treating Women with Preeclampsia.
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells.
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation.
SIRT5 alleviates hepatic ischemia and reperfusion injury by diminishing oxidative stress and inflammation via elevating SOD1 and IDH2 expression.
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Effects of Exosomes Derived from Adipose-Derived Mesenchymal Stem Cells on Pyroptosis and Regeneration of Injured Liver.
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure.
P2X7 Receptor-Induced Bone Cancer Pain by Regulating Microglial Activity via NLRP3/IL-1beta Signaling.
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
In Vitro Anti-Influenza A Virus H1N1 Effect of Sesquiterpene-Rich Extracts of Carpesium abrotanoides.
The Role of Nuclear Factor-Kappa B in Fibrinogen-Induced Inflammatory Responses in Cultured Primary Neurons.
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Altered Liver Metabolism, Mitochondrial Function, Oxidative Status, and Inflammatory Response in Intrauterine Growth Restriction Piglets with Different Growth Patterns before Weaning.
Guhong injection promotes post-stroke functional recovery via attenuating cortical inflammation and apoptosis in subacute stage of ischemic stroke.
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
TNFα-induced abnormal activation of TNFR/NF-κB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion.
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma.
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis.
Transcriptomics combined with metabolomics analysis of the mechanism of agmatine in the treatment of septic liver injury.
Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model.
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
Esculetin inhibits the pyroptosis of microvascular endothelial cells through NF-κB /NLRP3 signaling pathway.
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway.
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Transcriptional Regulation of RIP2 Gene by NFIB Is Associated with Cellular Immune and Inflammatory Response to APEC Infection.
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Blockade of mIL-6R alleviated lipopolysaccharide-induced systemic inflammatory response syndrome by suppressing NF-κB-mediated Ccl2 expression and inflammasome activation.
Kaempferol prevents the activation of complement C3 protein and the generation of reactive A1 astrocytes that mediate rat brain degeneration induced by 3-nitropropionic acid.
6-Gingerol exerts a protective effect against hypoxic injury through the p38/Nrf2/HO-1 and p38/NF-κB pathway in H9c2 cells.
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice.
A nucleation barrier spring-loads the CBM signalosome for binary activation.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
Carnosol inhibits osteoclastogenesis in vivo and in vitro by blocking the RANKL‑induced NF‑κB signaling pathway.
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
TBK1 participates in glutaminolysis by mediating the phosphorylation of RIPK3 to promote endotoxin tolerance.
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
Eplerenone inhibits UUO-induced lymphangiogenesis and cardiac fibrosis by attenuating inflammatory injury.
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response.
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
2-PMAP Ameliorates Cerebral Vasospasm and Brain Injury after Subarachnoid Hemorrhage by Regulating Neuro-Inflammation in Rats.
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Pharmacological inhibition of TLR4-NF-κB signaling by TAK-242 attenuates hydrocephalus after intraventricular hemorrhage.
18β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice.
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Chymotrypsin attenuates adjuvant-induced arthritis by downregulating TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6 expression in Sprague-Dawley rats.
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
1,25(OH)(2)D(3) alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway.
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
GABA regulates IL-1β production in macrophages.
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
FGF5 protects heart from sepsis injury by attenuating cardiomyocyte pyroptosis through inhibiting CaMKII/NFκB signaling.
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
Aerobic exercise improves intestinal mucosal barrier dysfunction through TLR4/MyD88/NF-κB signaling pathway in diabetic rats.
Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway.
Low-dose arsenite causes overexpression of EGF, TGFα, and HSP90 through Trx1-TXNIP-NLRP3 axis mediated signaling pathways in the human bladder epithelial cells.
Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide.
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway.
Administration of krill oil extends lifespan of fish Nothobranchius guentheri via enhancement of antioxidant system and suppression of NF-κB pathway.
Annexin-1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin-8.
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma.
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway.
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Harm of circadian misalignment to the hearts of the adolescent wistar rats.
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
Metadherin silencing results in the inhibition of pyroptosis in lipopolysaccharide/adenosine triphosphate - stimulated renal tubular epithelial cells.
Enzyme-instructed self-assembly of peptide-drug conjugates in tear fluids for ocular drug delivery.
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix.
Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway.
PRMT5 critically mediates TMAO-induced inflammatory response in vascular smooth muscle cells.
Preventive effects of the AMPA receptor potentiator LY450108 in an LPS-induced depressive mouse model.
Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.
Curcumin activates the Nrf2 Pathway to alleviate AFB1-induced immunosuppression in the spleen of ducklings.
A novel promoter-associated non-coding small RNA paGLI1 recruits FUS/P65 to transactivate GLI1 gene expression and promotes infiltrating glioma progression.
miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway.
Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats.
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Investigation on the Pathological Mechanism of Frequent Exacerbators With Chronic Obstructive Pulmonary Disease Based on the Characteristics of Respiratory Flora.
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Nuclear Factor Kappa-B/Homeobox A9-Mediated Modulation of Leucine-Rich Repeat Flightless-Interacting Protein 1 Is Involved in Advanced Glycation End Product-Induced Endothelial Dysfunction.
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
l-Theanine Ameliorates d-Galactose-Induced Brain Damage in Rats via Inhibiting AGE Formation and Regulating Sirtuin1 and BDNF Signaling Pathways.
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway.
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment.
The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain.
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Quercetin Preserves Oral Cavity Health by Mitigating Inflammation and Microbial Dysbiosis.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation.
Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages.
Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68 Infection-Induced Proinflammatory Responses.
Maternal Overnutrition During Gestation in Sheep Alters Autophagy Associated Pathways in Offspring Heart.
Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study.
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise.
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Cigarette smoking induces aberrant N(6)-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells.
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration.
Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats.
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway.
Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway.
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM(2.5)-induced lung injury in rats by modulating the NF-κB pathway.
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Targeted regulation of lymphocytic ER stress response with an overall immunosuppression to alleviate allograft rejection.
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity.
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Cordyceps acid alleviates lung cancer in nude mice.
Crosstalk between adipocytes and M2 macrophages compensates for osteopenic phenotype in the Lrp5-deficient mice.
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
MiR-519d-5p modulates the sensitivity of breast cancer to chemotherapy by forming a negative feedback loop with RELA.
IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice.
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity.
Baicalein Delays H(2)O(2)-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Adjuvant treatment and molecular mechanism of probiotic compounds in patients with gastric cancer after gastrectomy.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
miR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons.
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Inhibitory activity of narirutin on RBL-2H3 cells degranulation.
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Inflammatory signals induce MUC16 expression in ovarian cancer cells via NF-κB activation.
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution.
Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway.
m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Ripened Pu-erh Tea Extract Promotes Gut Microbiota Resilience against Dextran Sulfate Sodium Induced Colitis.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
HUCMSCs transplantation combined with ultrashort wave therapy attenuates neuroinflammation in spinal cord injury through NUR77/ NF-κB pathway.
Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway.
Protection Mechanisms Underlying Oral Administration of Chlorogenic Acid against Cadmium-Induced Hepatorenal Injury Related to Regulating Intestinal Flora Balance.
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Bergenin alleviates H(2) O(2) -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Morinda officinalis oligosaccharides alleviate depressive-like behaviors in post-stroke rats via suppressing NLRP3 inflammasome to inhibit hippocampal inflammation.
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
ILC2s induce adaptive Th2-type immunity in different stages of tuberculosis through the Notch-GATA3 pathway.
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice.
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Protective effects of miR-155-5p silencing on IFN-γ-induced apoptosis and inflammation in salivary gland epithelial cells.
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.
Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages.
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions.
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.
Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility.
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health.
Effects of Saccharides from Arctium lappa L. Root on FeCl(3)-Induced Arterial Thrombosis via the ERK/NF-κB Signaling Pathway.
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets.
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R(-/-)) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model.
Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activation of Th17 Cells in Treatment for Psoriasis.
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Astragaloside IV Improves High-Fat Diet-Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway.
Chemical Fingerprint Analysis and Ultra-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Study of the Protective Effect of Buxue Yimu Granule in Medical-Induced Incomplete Abortion Rats.
Inhibitory Effects of the Lactobacillus rhamnosus GG Effector Protein HM0539 on Inflammatory Response Through the TLR4/MyD88/NF-кB Axis.
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells.
Serine Supports IL-1β Production in Macrophages Through mTOR Signaling.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer.
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway.
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Copper induces oxidative stress with triggered NF-κB pathway leading to inflammatory responses in immune organs of chicken.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
TLR4 contributes to the damage of cartilage and subchondral bone in discectomy-induced TMJOA mice.
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.
Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition.
Influence of feature rankers in the construction of molecular activity prediction models.
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway.
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Tle1 attenuates hepatic ischemia/reperfusion injury by suppressing NOD2/NF-κB signaling.
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats.
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE(2)/MMP-2 in Mouse Offspring.
The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.
Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.
The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation.
Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma.
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Baicalein attenuates the neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines, COX2/NF-κB expressions and regulation of metabolic abnormality.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis.
N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts.
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl(4)-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis.
Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport.
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Saturated fatty acids activate the inflammatory signalling pathway in Schwann cells: Implication in sciatic nerve injury.
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
The response of phenoloxidase to cadmium-disturbed hepatopancreatic immune-related molecules in freshwater crayfish Procambarus clarkii.
Therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy in mice.
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice.
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.
Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling.
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways.
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer.
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Hydrocortisone Suppresses Early Paraneoplastic Inflammation And Angiogenesis To Attenuate Early Hepatocellular Carcinoma Progression In Rats.
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer.
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Gardenia Decoction Prevent Intestinal Mucosal Injury by Inhibiting Pro-inflammatory Cytokines and NF-κB Signaling.
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation.
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Light-induced Nrf2(-/-) mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel.
Synthesis and biological evaluation of (1,2,4)triazole[4,3-a]pyridine derivatives as potential therapeutic agents for concanavalin A-induced hepatitis.
TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Effect of Intranasal Instillation of Lipopolysaccharide on Lung Development and Its Related Mechanism in Newborn Mice.
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing.
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets.
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFβ/Smad3 and NF-κB signalling in a mouse model of hypertension.
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
Mucin 1 downregulation impairs the anti-necroptotic effects of glucocorticoids in human bronchial epithelial cells.
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Conjugated Linoleic Acid Ameliorates High Fructose-Induced Hyperuricemia and Renal Inflammation in Rats via NLRP3 Inflammasome and TLR4 Signaling Pathway.
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
GABA(B) receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK.
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner.
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer.
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Polychlorinated Biphenyl Quinone Promotes Macrophage-Derived Foam Cell Formation.
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway.
KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly.
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli.
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
microRNA-98 protects sepsis mice from cardiac dysfunction, liver and lung injury by negatively regulating HMGA2 through inhibiting NF-κB signaling pathway.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway.
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Quercetin reduces Streptococcus suis virulence by inhibiting suilysin activity and inflammation.
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
MiR-92a contributes to the cardiovascular disease development in diabetes mellitus through NF-κB and downstream inflammatory pathways.
Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activity.
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease.
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway.
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
HIV-1 Tat increases BAG3 via NF-κB signaling to induce autophagy during HIV-associated neurocognitive disorder.
The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice.
IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice.
Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway.
Clostridium butyricum protects the epithelial barrier by maintaining tight junction protein expression and regulating microflora in a murine model of dextran sodium sulfate-induced colitis.
Resveratrol induces apoptosis in SGC-7901 gastric cancer cells.
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Protective roles of NRF2 signaling pathway in cobalt chloride-induced hypoxic cytotoxicity in human HaCaT keratinocytes.
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injury.
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes.
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Macrophages mediate corticotomy-accelerated orthodontic tooth movement.
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway.
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling.
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury.
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells.
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
JMJD6 exerts function in neuropathic pain by regulating NF‑κB following peripheral nerve injury in rats.
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Isosteviol ameliorates diabetic cardiomyopathy in rats by inhibiting ERK and NF-κB signaling pathways.
Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis.
Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Functional Role of SUV39H1 in Human Renal Tubular Epithelial Cells Under High-glucose Ambiance.
Editor's Highlight: Effects of Intraperitoneal Injection of SnS2 Flowers on Mouse Testicle.
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Correlation between the expression of IL‑18 and deep venous thrombosis.
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation.
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Collagen gel protects L929 cells from TNFα-induced death by activating NF-κB.
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Interleukin-17A Plays the Same Role on Mice Acute Lung Injury Respectively Induced by Lipopolysaccharide and Paraquat.
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways.
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation.
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Comparative study of macrophages in naked mole rats and ICR mice.
miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
From the Cover: Activation of NF-κB-Autophagy Axis by 2-Hydroxyethyl Methacrylate Commits Dental Mesenchymal Cells to Apoptosis.
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway.
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge.
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells.
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer.
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy.
Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
miR-34a and its novel target, NLRC5, are associated with HPV16 persistence.
Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells.
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration.
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
The role of STIM1 in the Cr(vi)-induced [Ca(2+)](i) increase and cell injury in L-02 hepatocytes.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway.
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation.
Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway.
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma.
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Potent effects of dioscin against obesity in mice.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Potent effects of dioscin against liver fibrosis.
Sinomenine sensitizes multidrug-resistant colon cancer cells (Caco-2) to doxorubicin by downregulation of MDR-1 expression.
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Protective effects of dioscin against alcohol-induced liver injury.
Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway.
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis.
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Fluoride-elicited developmental testicular toxicity in rats: roles of endoplasmic reticulum stress and inflammatory response.
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice.
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.
Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability.
Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats.
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
Gu A, Wang B, Zhang Y, Sun C, Wei Y, Yan J, Yang Y, Wang Y, Liu R, Zhang R, Liu J, Gu C, Wang Y
Research (Washington, D.C.) 2026;9:1069
Research (Washington, D.C.) 2026;9:1069
Response surface methodology optimization extraction of polysaccharide from Lilium brownii F.E. Brown var. viridulum Baker/Longya Baihe and its biological activities.
Li M, He R, Yang C, Chen H, Wu C, Zhang X, Fu X, Lu C, Yang L, Liu S, Zhang Y
Preparative biochemistry & biotechnology 2026;56(4):593-607
Preparative biochemistry & biotechnology 2026;56(4):593-607
DJ-1 alleviates high glucose-induced podocyte injury via activating ERK1/2 signaling.
Tian X, Li J, Han T, Zhang L, Lu P, Liu Y
PloS one 2026;21(4):e0346714
PloS one 2026;21(4):e0346714
TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model.
Song Q, Li D, Yuan Z, Zhang C, Wang J, Liao F, Xu P, Xiao Q
PloS one 2026;21(3):e0344474
PloS one 2026;21(3):e0344474
Enhancement of Psoriasis Treatment by Phellodendri Chinensis Cortex Carbon Dots (PCC-CDs) Through Modulation of the HMGB1/TLR4/MAPK/NF-κB Pathway.
Tian X, Kong H, Wang S, Zhang X, He C, Huang Y, Liu R, Dai E, Shang G, Zhang Y, Jinjun C, Sun Z, Qu H, Zhao Y
International journal of nanomedicine 2026;21:578399
International journal of nanomedicine 2026;21:578399
Benzydamine Attenuates Matrix Metalloproteinase-9 Expression Through Inhibition of ERK MAPK in Activated Human Monocytic Cells Under Hyperglycemic Condition.
Do AP, Shen YC, Cheng YW, Yang CH, Huang LC, Liu YC, Nurhan AD, Lee YM, Hsu SP, Hsiao G
Mediators of inflammation 2026;2026:6566666
Mediators of inflammation 2026;2026:6566666
Elucidating the Mechanism of Fusu Agent Against Sepsis-Induced Acute Respiratory Distress Syndrome via an Integrated Approach Combining Network Pharmacology, Molecular Dynamics Simulations, and Experimental Validation.
Jin N, Wang X, Lai M, Zou J, He L, Luo G, Zhou X, Gao P
Journal of inflammation research 2026;19:572866
Journal of inflammation research 2026;19:572866
Transcriptomics and Network Pharmacology Reveal Anti-Inflammatory and Anti-Oxidative Stress Mechanisms of Qingxuan Runmu Yin in Dry Eye Disease.
Zhao S, Wang J, Liu Y, Hu X, Gu C, Yao J
Journal of inflammation research 2026;19:516780
Journal of inflammation research 2026;19:516780
The mechanism of Vicenin-2 in ameliorating skin photoaging: involvement of m6A-modified macrophage polarization.
Zhou Y, Shuai W, Peng X, Li R, Chen M, Tan B, Mu Y, Duan X
Frontiers in pharmacology 2026;17:1778993
Frontiers in pharmacology 2026;17:1778993
Wuji Wan ameliorates ulcerative colitis by restoring impaired membrane transport.
Zhang J, Zhang Y, Guo Y, Sun Y, Li Y, Li Q, Chen Y, Wang Y, Yang Q, Zhang M, Weng X, Deng Z
Frontiers in pharmacology 2026;17:1718919
Frontiers in pharmacology 2026;17:1718919
Multi-omics reveals the protective mechanisms of Gastrodia elata ethyl acetate extract in vascular dementia.
Tao J, Xiao T, Zhang Z, Cheng J, Tan J, Zhao Z, Duan X
Frontiers in pharmacology 2026;17:1630783
Frontiers in pharmacology 2026;17:1630783
Macrophage-biomimetic nanomedicine for targeted therapy of abdominal aortic aneurysm via Nrf2/NF-κB pathway.
Luo Q, Meng W, Wang J, Zhang X, Meng Q, Hu M, Wei S, Yu X, Deng D, Zhang Y, Ma Z, Li S, Wang S, Zhang B, Ding J, Liu J, Zhou J
Theranostics 2026;16(7):3363-3383
Theranostics 2026;16(7):3363-3383
Microbiota-driven therapeutic efficacy of Hyperoside in ulcerative colitis and associated anxiety.
Yin L, Xu L, Shan YN, He Z, Li Y, Chen W
Frontiers in cellular and infection microbiology 2026;16:1734356
Frontiers in cellular and infection microbiology 2026;16:1734356
A multi-mics exploration of programmed cell death in non-obstructive azoospermia: identifying TLR4 as a central regulator and therapeutic target.
Yu Q, Yang Q, Yuan S, Zhao Y, Li W, Qiao J, Sun F, Li T
Frontiers in cell and developmental biology 2026;14:1742608
Frontiers in cell and developmental biology 2026;14:1742608
Extracellular vesicles from Li-Qi-Yang-Yin formula attenuate LPS-stimulated inflammatory injury in human colonic epithelial cells in vitro by delivering bioactive metabolites and suppressing the oxidative stress-inflammation axis.
Deng X, Zhang W, Xu L, Ong SS, Zhang Y, Jian T, Xu T
Frontiers in medicine 2026;13:1751807
Frontiers in medicine 2026;13:1751807
miR-146a/b-5p-IRAK1-NF-κB Axis Regulates Unexplained Recurrent Spontaneous Abortion.
He F, Fan S, Chen L, Lou J, Lin Z, Liu Y, Yan T, Zhang Y
Journal of molecular recognition : JMR 2026 May;39(3):e70030
Journal of molecular recognition : JMR 2026 May;39(3):e70030
Dual-loaded BMSCs-Metformin microgels promote cartilage repair through combined anti-inflammatory, antioxidant, and regenerative effects.
Li D, Wang Y, Yuan G, Zhou F, He H, Du X, Liu S, Gao W, Fan X, Liu Z, Ma B, Deng Z, Li S, Xu J
Biomaterials 2026 May;328:123805
Biomaterials 2026 May;328:123805
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Cai F, Chen W, Li Q, Chen S, Xu Y, Ren Y, Liu Y
Stem cell reviews and reports 2026 May;22(4):1811-1826
Stem cell reviews and reports 2026 May;22(4):1811-1826
Edible Bird's Nest Attenuates Neuroinflammation and Cognitive Impairment in a Model of Chronic Fatigue Syndrome.
Wang X, Wang D, Chai Y, Zhang Y, Wang H, Qu T, Zhang W, Yuan M, Gao S, Sun Y, Li Y
Food science & nutrition 2026 May;14:e71685
Food science & nutrition 2026 May;14:e71685
TEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Pu Y, Wan Y, Shi W, Li B, Zhang H, Wu J, Li L, Guo W, Ding C, Yang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e14104
d-amino acids restrain macrophage IL-1β release through gasdermin D acetylation.
Wu Z, Hu Q, Shen Y, Fu J, Liu B, Zhang M, Hung I, Liu C, Ren W
Science advances 2026 May;12(18):eaed1676
Science advances 2026 May;12(18):eaed1676
From multi-omics discovery to experimental validation: GPC4 mediates the anti-neuroinflammatory effects of Buyang Huanwu decoction via TLR4/NF-κB signaling in ischemic stroke with Qi deficiency and blood stasis syndrome.
Zhang C, Wu X, Yu Z, Xu G, Yang J, Shao C, Wan H
Journal of ethnopharmacology 2026 May 23;363:121375
Journal of ethnopharmacology 2026 May 23;363:121375
Salvia miltiorrhiza Bge. processed with porcine cardiac blood alleviates cerebral ischemia reperfusion injury through activating PPARγ/NF-κB pathway via suppressing arachidonic acid metabolism.
Zhou S, Jiang W, Sun Z, Zhang J, Zhang T, Ma B, Liu C, Zhang Y, Zhang L, Yan X
Journal of ethnopharmacology 2026 May 10;362:121385
Journal of ethnopharmacology 2026 May 10;362:121385
DysUFMylation reprograms immunosuppressive neutrophils to potentiate anti-PD-1 therapy in hepatocellular carcinoma.
Gao X, Xu M, Han Z, Hu Z, Su Y, Sun G, Chen W, Qiu S, Qiu S, Hung MC, Zhou C, Yi Y
Cancer letters 2026 May 1;645:218395
Cancer letters 2026 May 1;645:218395
SIRT4 regulates antiviral and autoimmune responses by promoting cGAS-mediated signaling pathways.
Yang B, Zhang Y, Wang S, Wu Y, Diao Z, Zhang Q, Lu C, Shen M, Zhang X, Ma S, Yang C, Pei J, Xing H, Liang Y, Wang J
EMBO reports 2026 Mar;27(5):1228-1253
EMBO reports 2026 Mar;27(5):1228-1253
Linderalactone mitigates diabetic renal injury by inhibiting macrophage inflammation via the Dectin1/Syk/CARD9/IRF5/NF-κB pathway.
Chen H, Xu S, Chen B, Xiong X, Hu J, Wu Y, Wang T, Wang H
Journal of diabetes investigation 2026 Mar;17(3):395-410
Journal of diabetes investigation 2026 Mar;17(3):395-410
Macrophage-derived galectin-3 contributes to pyroptosis, apoptosis and necroptosis through TLR4/MyD88/NF-κB/NLRP3 during atherosclerosis.
Yuan Z, Li H, Ruan BX, Huang H, Li Y, Wang J
Clinical and translational medicine 2026 Mar;16(3):e70637
Clinical and translational medicine 2026 Mar;16(3):e70637
Transdermal Delivery of Icariin via Microneedle Patches Attenuates Phthalate-Induced Testicular Injury.
Fang C, Li Y, You R, Wong KH, Cai T, Gan RY, Ye Y
Advanced healthcare materials 2026 Mar;15(9):e03925
Advanced healthcare materials 2026 Mar;15(9):e03925
Differential Effects of Saturated and Unsaturated Fatty Acids on Colorectal Cancer via IDO1 Signaling.
Zhang S, Zhang J, Chen J, Singab ANB, Yang G, Li J, Li P, Wu S, Zhao D, Sun J, Gao L, Lin G, Yu G, Iv Y, Wang H, Yuan L, Ye L
Cancer medicine 2026 Mar;15(3):e71644
Cancer medicine 2026 Mar;15(3):e71644
Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis.
Li H, Qiao Y, Ding M, Liu Y
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026 Mar-Apr;74(2):235-248
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2026 Mar-Apr;74(2):235-248
Maternal immune activation perturbs intestinal niche through microbial glycerophospholipids and drives offspring behavioral abnormalities.
Chang H, Zhu X, Shen C, Xu X, Ni Y, Zhang Y, Yan J, Xue J, Li C, Qin Q, Hai K, Hou M, Zhou Z, Ji M, Xu Z
Cell reports 2026 Mar 31;45(4):117211
Cell reports 2026 Mar 31;45(4):117211
A Biocompatible CMCHMA/F127DA Hydrogel with ROS-Scavenging Activity Prevents Postoperative Peritoneal Adhesions.
Xia Z, Wang W, He L, Xia Z, Li J, Dong Q
ACS omega 2026 Mar 31;11(12):19192-19200
ACS omega 2026 Mar 31;11(12):19192-19200
Rosa roxburghii Tratt Juice Inhibits Fluoride Exposure-Induced Bone Damage in Male Rats by Regulating the Homeostasis of the ROS/TNF-α/NF-κB Pathway.
Yang W, Ma L, Hu T, Zhang L, Wu K, Chen H, Zhang D, Luo P
Biological trace element research 2026 Mar 3;
Biological trace element research 2026 Mar 3;
Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.
Zeng B, Jiang G, Wang C, Zhou H, Zhang Y, Yan YN, Chen Z, Zhang L, Li X, Xie M, Yang Z, Wang H
Journal of molecular histology 2026 Mar 26;57(2)
Journal of molecular histology 2026 Mar 26;57(2)
Biglycan knockdown improves Graves' orbitopathy (GO)-like features via inhibiting NF-kB and ERK signaling.
Chenzhao C, Zhu M, Zhang F, Xie B, Cao J, Xiong W, Tan Y
Journal of endocrinological investigation 2026 Mar 2;
Journal of endocrinological investigation 2026 Mar 2;
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway.
Yuan Y, Jiang Y, Du S, Yuan G, Yang Z, Wang P
Inflammation 2026 Mar 12;49(1)
Inflammation 2026 Mar 12;49(1)
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Hao R, Sun Y, Wang C, Wang Y, Li L, Sun H, Chen L
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
miR-223-3p improves macrophage polarization balance and mitochondrial metabolism to ameliorate uveitis by orchestrating P65(Lys310) acetylation through RBPJ/HDAC1 axis.
Peng Y, Liu B, Xu S, Qu R, Zhang R, Wang C, Liu Y, Wei H, Tian Q, Zhang M, Bi H, Yin X, Guo D
Cellular & molecular biology letters 2026 Mar 10;31(1)
Cellular & molecular biology letters 2026 Mar 10;31(1)
Synergistic proanthocyanidin-copper oxygen-generating microneedle enhances anti-inflammatory activity in dental pulp stem cells and macrophage efferocytosis.
Miao Y, Wang Y, Yang Y, Luo Z, Wang Y, Lei B, Liu R
BMC oral health 2026 Mar 10;26(1)
BMC oral health 2026 Mar 10;26(1)
Yishen Qianggu Mixture formulation suppresses osteometabolic inflammation by modulating the IL-17/NF-κB/MAPK signaling axis.
Zhao J, Peng GG, Xiao D, Fu CJ, Chen HZ, Luo SJ, Wu HQ, Huang M
Journal of ethnopharmacology 2026 Mar 1;358:121011
Journal of ethnopharmacology 2026 Mar 1;358:121011
Total Extract of Folium Rhododendri Daurici alleviate MASLD by regulating PPAR and TNF signaling pathways.
Zhang Y, Yin Z, Zhang Y, Wei Y, Zhai Y, Zhao X, Zhan B, Wang Z, Feng H
Journal of ethnopharmacology 2026 Mar 1;358:120955
Journal of ethnopharmacology 2026 Mar 1;358:120955
Acrylamide exposure induces neurotoxicity via the PI3K/Akt/NF-κB pathway: Evidence from network toxicology and experimental validation.
Duan Z, Yu C, Yu Q, Yang W, Zhang R, Ruan Q, Zhao Y, Yan S
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Ecotoxicology and environmental safety 2026 Mar 1;312:119922
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
Yang H, Li Y, Xiao Z, Kuang M
Molecular carcinogenesis 2026 Jun;65(6):699-714
Molecular carcinogenesis 2026 Jun;65(6):699-714
M2 macrophage-derived exosomes delivering haptoglobin and interleukin-10 plasmids for synergistic therapy of intracerebral hemorrhage.
Wang K, Li J, He M, Wang L, Guo X, Zhou S
Bioactive materials 2026 Jun;60:510-526
Bioactive materials 2026 Jun;60:510-526
Untargeted Metabolomic Study of the Anti-HBV Effects of Erythrocentaurin In Vitro and In Vivo Using UPLC-Q-TOF/MS.
Wang Y, Tang S, Li P, Sun Y, Xu Y, Li H, Xu H, Wang Y, Zhang H, Li X, Wang Z
Biomedical chromatography : BMC 2026 Jun;40(6):e70447
Biomedical chromatography : BMC 2026 Jun;40(6):e70447
Research on the compatibility mechanism of the Tingli Dazao Xiefei Decoction by multi-organ metabolomics strategy.
Wang RF, Yuan PP, Chen L, Zhang ZK, Zhang BX, Chen L, Yuan SM, Zhao YF, Zhou N, Zheng XK, Feng WS
Journal of ethnopharmacology 2026 Jun 28;365:121548
Journal of ethnopharmacology 2026 Jun 28;365:121548
Inhibiting fibroblast activation protein mitigates aging-related periodontitis by blocking nuclear factor kappa B-mediated osteoclastogenesis.
Sun Y, Zou H, Cui A, Dong H, Pawuziya A, Zhao P, Wang J, Leung WK, Wang Q
International immunopharmacology 2026 Jun 15;179:116647
International immunopharmacology 2026 Jun 15;179:116647
Ethnopharmacological relevance and anti-inflammatory mechanisms of Lycopi Herba in diabetic nephropathy: Integrated chemical profiling and pharmacological evaluation.
Chen LZ, Yang S, Ren DM, Wang XL, Shen T, Wang XN
Journal of ethnopharmacology 2026 Jun 12;364:121505
Journal of ethnopharmacology 2026 Jun 12;364:121505
Virus-inspired Ganoderma lucidum polysaccharide-functionalized adjuvant with pseudo-zwitterionic interface for potentiated nasal immunization.
Liu XH, Zhai Z, Tao LL, Chen NY, Cheng YX
Carbohydrate polymers 2026 Jun 1;381:125183
Carbohydrate polymers 2026 Jun 1;381:125183
Targeted inhibition of microglial C5aR1 by PMX205 mitigates post-ischemic stroke neuroinflammation and promotes functional recovery.
Cao J, Tian S, Deng Z, Xu J, Liu Y, Shi X, Bai L, Li X Jr, Li H
Brain research bulletin 2026 Jun 1;239:111873
Brain research bulletin 2026 Jun 1;239:111873
High-throughput RNA sequencing identifies hub genes and anti-inflammatory effects of β-caryophyllene in cerebral ischemia-reperfusion via p38MAPK/NF-κB modulation.
Liu J, Li Z, Wen J, Liu S, Ji J, Yang J, Wang S, Wang Y, Liu H
Brain research bulletin 2026 Jun 1;239:111857
Brain research bulletin 2026 Jun 1;239:111857
ACOT8-mediated palmitate accumulation promotes M1 macrophage polarization in renal ischemia-reperfusion injury via activation of the cGAS-STING pathway.
Zhang H, Liu X, Ji X, Zhang G, Wang B, Xiong F, Sun D, Wang C
International immunopharmacology 2026 Jun 1;178:116558
International immunopharmacology 2026 Jun 1;178:116558
Inflammation-induced cell-secreted migrasome promotes IL-6 expression in the recipient cells.
Saito S, Yoshikawa K, Tanaka M, Murakami M, Okochi M
Biomaterials advances 2026 Jul;184:214793
Biomaterials advances 2026 Jul;184:214793
Protective effects of the ethyl acetate fraction from Madeng'ai on lipopolysaccharide-induced acute lung injury in mice: Insights from integrated multi-omics analysis.
Zhang Z, Zhu T, Cao L, Wang Y, Xing XL, Zhang Z
Journal of ethnopharmacology 2026 Jul 15;366:121650
Journal of ethnopharmacology 2026 Jul 15;366:121650
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation.
Qu Z, Ding Y, Zhang L, Sun J, Wang T, Zhuang C
Free radical research 2026 Jan;60(1):1-15
Free radical research 2026 Jan;60(1):1-15
Piperine Inhibits the Immune Checkpoint CD47 to Enhance Immunity Against Pancreatic Cancer.
He X, Lu Y, Zhang H, Lin B, Lu H, Yu Z, Li Y, Xi Q, Zhang R
Phytotherapy research : PTR 2026 Jan;40(1):194-212
Phytotherapy research : PTR 2026 Jan;40(1):194-212
λ-Carrageenan regulates antiviral responses by targeting classical NF-κB and IRF3-mediated signaling pathways.
Sun X, Yao W, Hu J, Zhang Y, Liu R, Hu W, Li Y, Wan B, Kong Z, Zhang G
International journal of biological macromolecules 2026 Jan;338(Pt 2):149760
International journal of biological macromolecules 2026 Jan;338(Pt 2):149760
Bushen Huoxue formula component β-Estradiol 3-acetate treats osteoarthritis through enhancing the TLR4 ubiquitination.
Liu X, Wang S, Kuang C, Deng Y, Yuan S, Zou J
The Journal of steroid biochemistry and molecular biology 2026 Jan;255:106862
The Journal of steroid biochemistry and molecular biology 2026 Jan;255:106862
Salidroside ameliorates experimental autoimmune neuritis by dually modulating neuroinflammation and immune homeostasis via PI3K/AKT signaling.
Gu T, Wang L, Kang X, Yu C, Shen K, Song M, Gao Y, Wang G, Wang Z
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00769
Chlorogenic acid targets STING to alleviate pressure overload-induced heart failure and myocardial fibrosis.
Huang K, Xiao JL, Tang JY, Pu HY, Li FH, Gao K, Yu X, Guo SZ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157625
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157625
Kaempferitrin Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction Through Suppression of the NF-κB/NLRP3 Signaling Pathway.
Kuang H, Li Q, Chen M, Du H
Immunity, inflammation and disease 2026 Jan;14(1):e70323
Immunity, inflammation and disease 2026 Jan;14(1):e70323
Periodontitis pathogen Porphyromonas gingivalis promotes chronic obstructive pulmonary disease via affecting neutrophils chemotaxis and function.
Zhang L, Tian H, Ma Y, Xu J, Guo C, Wang Z, Ma J
International journal of oral science 2026 Jan 9;18(1):4
International journal of oral science 2026 Jan 9;18(1):4
Chlorella-derived extracellular vesicle-based nanogels suppress cGAS-STING for treatment of radiation-induced lung injury.
Hu H, Lu F, Zhang W, Zhang Z, Cui J, Lei X, Xia J, Xu F
Nature communications 2026 Jan 8;17(1):1403
Nature communications 2026 Jan 8;17(1):1403
Multi-omics reveals cholesterol-driven macrophage metabolic reprogramming and inflammation in chronic obstructive pulmonary disease.
Ran X, Yang Z, Cheng L, Li W, Cui J, Huang P, Wang Z, Mao Z, Yi E, Tian Y, Li P, Zhou Y, Ran P, Guo F
Genome medicine 2026 Jan 5;18(1):17
Genome medicine 2026 Jan 5;18(1):17
Wumei Wan ameliorates ulcerative colitis in rats by modulating the inflammation-pyroptosis-intestinal stem cell axis.
Zhang Y, Ge F, Qu H, Zhao C, Gu J, Xu Q, Lei H, Liu J, Wang X, Chu Y, Yu X, Zhang D, Zhang D, Zhang S, Han K, Chen M
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120645
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120645
Sensitising PDAC to Gemcitabine by Suppressing NF-κB Pathway and Enhancing Apoptosis.
Jin E, Simões MRGDS, O'Hagan S, Jin E, Day PJ
Pharmaceuticals (Basel, Switzerland) 2026 Jan 30;19(2)
Pharmaceuticals (Basel, Switzerland) 2026 Jan 30;19(2)
Functional food potential of Anoectochilus roxburghii aqueous extract: UPLC-MS profiling and in vivo efficacy in type 2 diabetic mice.
Li P, Ran B, Li Z, Zhang Y, Wang Y, Li W
Journal of the science of food and agriculture 2026 Jan 30;106(2):961-974
Journal of the science of food and agriculture 2026 Jan 30;106(2):961-974
Protective effects of Curcumin-Zinc complex on inflammatory damage of IPEC-J2 cells induced by bacterial lipopolysaccharide.
Tang X, Zeng Y, Li M
AMB Express 2026 Jan 3;16(1):13
AMB Express 2026 Jan 3;16(1):13
MALT1 Knockdown Alleviates Multiorgan Injury and Inflammation Through Inhibiting TAK1/NF-κB Signaling Pathway-Mediated T-Helper 1 and 17 Differentiations in LPS-induced Inflammation.
Huang Q, Luo Y, Chen Q, Cui Y
Inflammation 2026 Jan 26;49(1):69
Inflammation 2026 Jan 26;49(1):69
A DNA-based nanodevice senses purinergic signaling and drives an immune switch for resolving inflammation.
Li W, Liu S, Zhou X, Lv K, Liu F, Chen H, Li R, Xiao J, Ma Y, Yang H, Zhang C, Liu J
Nature communications 2026 Jan 26;17(1)
Nature communications 2026 Jan 26;17(1)
Bu-Shen-Tian-Jing Formula alleviates oxidative-inflammatory stress in granulosa cells of polycystic ovary syndrome through AGEs-RAGE/NOX4/NF-κB pathway.
Zhang Q, Ren J, Ye J, Chen F, Xiang F, Shi B, Zhou Z, Zhou J, Wang F, Qu F
Chinese medicine 2026 Jan 23;21(1):50
Chinese medicine 2026 Jan 23;21(1):50
Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signaling.
Chen C, Ma L, Dawuti A, Feng X, Chen S, An X, Bai Y, Zhang T, Aydin M, Kashmiri K, Ma Z, Zhang W, Yaermaimaiti S, Abulizi A
NPJ science of food 2026 Jan 23;10(1):73
NPJ science of food 2026 Jan 23;10(1):73
Esketamine alleviates COPD-depression comorbidity in rats via MAPK/NF-κB inhibition and gut-lung-brain axis modulation.
Liu A, Zhang XQ, Guo JX, Wen QY, Dai K, Zheng WJ, Wu JH, Li CY, Chen ZY
Journal of neuroinflammation 2026 Jan 22;23(1):68
Journal of neuroinflammation 2026 Jan 22;23(1):68
Rhodotorula mucilaginosa JAASSRY1 Ameliorates Cyclophosphamide-Induced Immunosuppression by Regulating Gut Microbiota and Activation of Spleen TLR4/MyD88/NF-κB Pathway.
Yang M, He Y, Miao X, Sun M, Niu H, Hua M, Li D, Xu H, Wang J
Journal of microbiology and biotechnology 2026 Jan 21;36:e2510031
Journal of microbiology and biotechnology 2026 Jan 21;36:e2510031
TA-Zr/Ce Nanozyme-Mediated Lipopolysaccharide Dephosphorylation: A Targeted Strategy for Sepsis Treatment with Hemoperfusion Applications.
Zhao X, Shao R, Yu Y, Hu Z, Jiang Y, Zhou Y, Zhong Z, Zhou J
ACS nano 2026 Jan 20;20(2):2523-2544
ACS nano 2026 Jan 20;20(2):2523-2544
CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation.
Li N, Huang E, Wang R, Li J, Yuan X
Stem cell research & therapy 2026 Jan 17;17(1):83
Stem cell research & therapy 2026 Jan 17;17(1):83
Huashi Baidu granules alleviates LPS-induced acute lung injury by targeting TACE-mediated inflammatory signaling and stress granules disassembly.
Ma Y, Zhang J, Gong J, Yang W, Huang J, Sun Y
Journal of ethnopharmacology 2026 Jan 10;354:120580
Journal of ethnopharmacology 2026 Jan 10;354:120580
Decoding the healing secrets of Gegenqinlian decoction: A promising approach to radiation-induced intestinal injury.
Zhang M, Wang SJ, Du XQ, Li GA, Yu YY, Zhang YQ, Liu WJ, Song F, Cao W, Sun Y, Li XQ
Journal of ethnopharmacology 2026 Jan 10;354:120473
Journal of ethnopharmacology 2026 Jan 10;354:120473
STING knockdown blocks disease progression and inflammation in mice with alcoholic liver disease by relieving pyroptosis via suppressing NLRP3.
Song Y, Liu M, Zhou M, Ren X, Feng B, Xie Y
International immunopharmacology 2026 Jan 1;168(Pt 2):115858
International immunopharmacology 2026 Jan 1;168(Pt 2):115858
M1-like tumor-associated macrophages promote colorectal cancer progression through feedback activation of the IL1β/NF-κB signaling activity.
Xu X, Wang X, Luo Z, Parveen R, Zhang J, Zhou Y, Chen R, Ye Y, Guo J, Huang G, Wang Y, Ma G
International immunopharmacology 2026 Jan 1;168(Pt 1):115845
International immunopharmacology 2026 Jan 1;168(Pt 1):115845
Adiponectin attenuates atherosclerosis via macrophage polarization-mediated T Cell exhaustion by modulating the NF-κB p65/PI3K/Akt signaling pathway.
Qin M, Xu S, Chen Y, Luo X, Tang X, Zhang L, Xu Q
Tissue & cell 2026 Feb;98:103150
Tissue & cell 2026 Feb;98:103150
Immunomodulatory effects of bacterial lysates on the IL-17 signaling pathway in an asthma mouse model.
Gao M, Wang X, Yin L, Wei X, Li F
The Journal of asthma : official journal of the Association for the Care of Asthma 2026 Feb;63(2):159-168
The Journal of asthma : official journal of the Association for the Care of Asthma 2026 Feb;63(2):159-168
Glycyrrhizic acid-loaded biomimetic hybrid liposomes targeting inflammatory cascades and PD-1/PD-L1 pathway to reverse neuroinflammation-driven cognitive decline.
Wang Y, Luo F, Zhang P, Niu H, Tan Y, Zhang Y, Tang Z, Du L, Jin Y, Jin X
Materials today. Bio 2026 Feb;36:102657
Materials today. Bio 2026 Feb;36:102657
A novel biomimetic nanozyme orchestrates ulcerative colitis resolution by targeting KEAP1-NRF2-ARE pathway: Redox balance restoration, colonic barrier repair, immune homeostasis regulation.
Gong P, Wang Y, Qiu JH, Li G, Chen KW, Li Z, Wang X, Wang L
Materials today. Bio 2026 Feb;36:102627
Materials today. Bio 2026 Feb;36:102627
Inhibition of SCD1 attenuates neuroinflammation and brain injury after cerebral ischemia-reperfusion.
Li S, Li X Jr, Peng L, Ding H, Shi X, Liu J, Li H, Xu J, Sun Q
Brain research bulletin 2026 Feb;235:111693
Brain research bulletin 2026 Feb;235:111693
Macrophage USP14 suppresses Wnt/β-catenin signaling via NLK deubiquitination to enhance immune response.
Zhao M, Shi J, Wei X, Tian W, Chen Y
Cytokine 2026 Feb;198:157079
Cytokine 2026 Feb;198:157079
MD2 mediates COPD pathogenesis by inducing airway inflammation and ferroptosis through the TLR4/MyD88 pathway.
Xi X, Chen H, Ji H, Xiao T, Liu Z, Chen J, Ge X, Zhang Y, Zhu X
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168099
Biochimica et biophysica acta. Molecular basis of disease 2026 Feb;1872(2):168099
Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.
Ye S, Xiang J, Zhou S, Ge Q, Anwaier A, Chang K, Wei G, Lu J, Tian X, Zhu S, Jiang Y, Zhang W, Cai T, Xu M, Ye D, Xu D, Wang T, Zhang H, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18500
Icaritin Ameliorates Cisplatin-Induced Mitochondrial Metabolic Dysfunction-Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy.
Luo P, Chen J, An Y, Meng K, Zhou W, Li W, Liu J, Zhao W, He W, Cao T, Huang J, Feng S, Yang S, Hu H, Liao J, He H, Hao M, Zhang Q, Wang J, Gao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e06712
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e06712
DLGAP5 regulates malignancy and lenvatinib sensitivity of hepatocellular carcinoma through AKT/mTOR/NF-κB pathway.
He B, Deng M, Guan R, Mei J, Zou H, Tang Y, Yang Z, Zheng Z, Lin W, Li S, Guo R, Zhao R, Wei W
European journal of medical research 2026 Feb 9;
European journal of medical research 2026 Feb 9;
Inhibition of galanin receptor 3 slows down retina degeneration in retinitis pigmentosa through modulation of inflammatory and oxidative stress response.
Azam M, Pashandi Z, Liu M, Jastrzebska B
Scientific reports 2026 Feb 7;16(1)
Scientific reports 2026 Feb 7;16(1)
Artemisia Extracts Suppress H1N1 Influenza A Virus Infection by Targeting Viral HA/NA Proteins and Modulating the TLR4/MyD88/NF-κB Signaling Axis.
Hu Z, Liu H, Wu W, Ali T, Junka A, Sharopov FS, Zou X, Fang S, Sun Y
Pharmaceuticals (Basel, Switzerland) 2026 Feb 6;19(2)
Pharmaceuticals (Basel, Switzerland) 2026 Feb 6;19(2)
Study on the antioxidant and anti-inflammatory properties of different morphologies of ceria nanoenzymes with multi enzyme mimetic activity.
Song Z, Lu Y, Xiang M, Wen K, Liu Q
Journal of materials science. Materials in medicine 2026 Feb 4;37(1):34
Journal of materials science. Materials in medicine 2026 Feb 4;37(1):34
Exploration of borneol essential oil function in the treatment of Alzheimer's disease based on network pharmacology and experimental validation.
You C, Wu S, Zhang Y, Li Q, Cui Y, Wu Y
BMC complementary medicine and therapies 2026 Feb 4;26(1)
BMC complementary medicine and therapies 2026 Feb 4;26(1)
Knockout of the C4BPA Gene Promotes Mitophagy via Activation of the Pink1/Parkin Pathway and Alleviates the Inflammatory Response by Inhibiting the NF-κB Signalling Pathway in Bovine Mammary Epithelial Cells.
Zhou Y, Zhao Z, Chen X, Shao W, Lu Q, Tao Q, Xu Q, Chen R, Jiang P, Lin Z, Yu H
Veterinary sciences 2026 Feb 4;13(2)
Veterinary sciences 2026 Feb 4;13(2)
Study on the mechanism of Sangbaipi Decoction in treating acute lung injury via the inflammasome NLRP3 signaling pathway.
Xu B, Wang Y, Xu Y, Zhang X, Wang X, Chen S, Li L, Bao H
Journal of ethnopharmacology 2026 Feb 28;357:120908
Journal of ethnopharmacology 2026 Feb 28;357:120908
Electroacupuncture Attenuates Neuroinflammation and Postoperative Cognitive Dysfunction in Aged Rats by Suppressing the cGAS-STING Pathway.
Ma B, Fan S, Deng J, Wei K, Li Y, Yin J, Xie L
Experimental neurobiology 2026 Feb 28;35(1):42-55
Experimental neurobiology 2026 Feb 28;35(1):42-55
Machine learning identifies a DNA repair-related risk model for bladder cancer and functionally characterizes ZWINT as a potential oncogenic factor.
Liang S, Liu H, Su Q, Li X, Yang Z, Mo W
Translational andrology and urology 2026 Feb 28;15(2):46
Translational andrology and urology 2026 Feb 28;15(2):46
Uncovering the Potential Mechanisms of Ergothioneine in Neuroinflammation Through Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and In Vitro Validation.
Cao D, Jia J, Yin Y, Lu W
International journal of molecular sciences 2026 Feb 26;27(5)
International journal of molecular sciences 2026 Feb 26;27(5)
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
Zhang H, Zhang D, Wang Z, Liu K, Xu C, Sun H, Yan Z, Li C, Lu B, Yin Y, Zhao C, Niu Y, Li W
Biology direct 2026 Feb 26;21(1)
Biology direct 2026 Feb 26;21(1)
Simulated microgravity affects neuronal synaptic plasticity by regulating microglial pro-inflammatory activation.
Chen X, Yuan C, Li Z, Zhao T, Yang Y, Wang Y, Qiao C, Liu Z, Li X
NPJ microgravity 2026 Feb 26;12(1)
NPJ microgravity 2026 Feb 26;12(1)
HOXA10 drives immune evasion in early lung adenocarcinoma by recruiting immunosuppressive macrophages via NF-κB/CCL2 signaling.
Ma J, Xu X, Zhu J, Wang J, Wang L, Liu Y, Qiu W
Journal of experimental & clinical cancer research : CR 2026 Feb 25;45(1)
Journal of experimental & clinical cancer research : CR 2026 Feb 25;45(1)
The HEAT repeat protein MROH7 regulates the inflammatory macrophage response via LBP acetylation.
Zhang H, Fu J, Guo Y, Liu S, Mei X, Zeng X, Ren W
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Cell chemical biology 2026 Feb 19;33(2):169-182.e5
Monocyte-macrophage SAMHD1 alleviates EAMG by modulating the cGAS-STING pathway.
Que W, Fan R, Lu D, Liu L, Dong J, Ke P, Jing S, Gan Y, Xiao F
Journal of neuroinflammation 2026 Feb 19;23(1)
Journal of neuroinflammation 2026 Feb 19;23(1)
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation.
Sun R, Fan H, Ma Q, Li X, Liu J, Xu C, Liu C, Zhang D, Ma W
Free radical biology & medicine 2026 Feb 16;244:422-434
Free radical biology & medicine 2026 Feb 16;244:422-434
Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression.
Luo Z, Xu G, Li C, Sun Z, Chen H, Yang M, Ye Y, Chen Q, Xu B, Luo H, Sun B
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
Journal of medicinal chemistry 2026 Feb 12;69(3):3457-3476
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
Zhu Y, Chen L, Lin J, Chen M, Wu W, Chen Y, Xuan L
Journal of ethnopharmacology 2026 Feb 10;356:120656
Journal of ethnopharmacology 2026 Feb 10;356:120656
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
Zhang Z, Shen H, Zhang S, Zhou J, Zhang M, Wang Y, Zheng Y, Chang Y, Liang X, Hu X, Gao W
International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
S-methylmethionine ameliorates renal injury in diabetic mice by modulating macrophage inflammaging via ERK/NF-κb signaling pathway.
Dong H, Shen L, Abulizi P, Sun Y, Nie L, Cui A, Fu Q, Ji N, Luo Y, Chen C, Xu A, Leung WK, Wang Q
International immunopharmacology 2026 Feb 1;170:116038
International immunopharmacology 2026 Feb 1;170:116038
Mechanisms of topical Mahoniae Caulis against acute mastitis: Integrating SMR, network pharmacology, molecular docking, and experimental validation.
Feng S, Zhou N, Wang T, Wang Y, Shu R, Liu Y, Lyu G
Tissue & cell 2026 Aug;101:103472
Tissue & cell 2026 Aug;101:103472
Nao-Xin-Tong Capsule alleviates astrocyte end-foot swelling after cerebral ischemia-reperfusion injury via NF-κB/MMP9/AQP4 signal and NF-κB/CXCL12/CXCR4 signal.
Shang J, Wei W, Wang B, Wei R, Cui Y, Wang J, Liu X
Journal of ethnopharmacology 2026 Aug 10;367:121761
Journal of ethnopharmacology 2026 Aug 10;367:121761
Mogrosides from S. grosvenorii ameliorate acute pharyngitis via the PI3K/AKT-NF-κB-NLRP3 signaling pathway and oxidative stress modulation.
Wu J, Huang H, Mao J, Chen G, Zhan S, Peng Z, Zhu Y, Wang W
Journal of ethnopharmacology 2026 Aug 10;367:121594
Journal of ethnopharmacology 2026 Aug 10;367:121594
Quercetin targeted NF-κB to regulate platelet activation and prevent arterial thrombosis.
Wang W, Li Y, Liu Y, Sun Z, Zhao B, Song F
Tissue & cell 2026 Apr;99:103270
Tissue & cell 2026 Apr;99:103270
Targeting PTGS2/NF-κB Pathway: MG-132's Role in Reducing Ischemic Stroke Injury.
Wang YS, Huang YC, Wang YQ, Zheng YX, Gao YR, Wu MX, Gao FH, Wang HZ, Liu K, Yan L
Biochemical genetics 2026 Apr;64(2):2546-2564
Biochemical genetics 2026 Apr;64(2):2546-2564
Tanshinone IIA attenuates airway inflammation and airway remodeling in bronchial asthma by inhibiting p38/NF-κB and AKT/HIF-1α.
Yu W, Peng Z, Lü B, Yu Y, Chen J
The Journal of asthma : official journal of the Association for the Care of Asthma 2026 Apr;63(4):428-438
The Journal of asthma : official journal of the Association for the Care of Asthma 2026 Apr;63(4):428-438
Macrophage C3aR1 Mediates Sepsis-Induced Myocardial Injury by Triggering Neutrophil Necroptosis.
Xu J, He Z, Zhang R, Peng C, Cai Z, Zhao X, Wang W
Journal of cellular and molecular medicine 2026 Apr;30(8):e71145
Journal of cellular and molecular medicine 2026 Apr;30(8):e71145
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Chen MH, Hua YJ, Li Y, Lei Y, Zhou SY, Hu XD, Hu DH, Dong ZH, Lu Y, Zhuang T, Ruan CC
Nature immunology 2026 Apr;27(4):738-749
Nature immunology 2026 Apr;27(4):738-749
TRIM25 triggers pyroptosis through mitochondrial DNA release in intestinal ischemia-reperfusion injury.
Song Y, Lu X, Ren X, Li M, Meng F, Miao Y, Ding D, Liu Y
Free radical biology & medicine 2026 Apr;247:333-347
Free radical biology & medicine 2026 Apr;247:333-347
Development of ellagic acid-derived bismuth MOF for targeted therapy in colitis.
Wang Y, Huang X, Luo X, He M, Fang Y, Yang D
Biomaterials advances 2026 Apr;181:214646
Biomaterials advances 2026 Apr;181:214646
Zinc-doped carbon dots from natural Isatis Indigotica folium and calamine: SOD/CAT-mimetic activity targets ROS-Ca²⁺-NLRP3 axis for psoriatic dermatitis therapy.
Tian X, Huang Y, He C, Dai E, Zhang X, Zou P, Liu R, Xia M, Lu Z, Jin B, Wang S, Zhang Y, Kong H, Qu H, Zhao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:158013
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:158013
Alkaloids of Calanthe davidii ameliorate STZ-induced diabetes by suppressing oxidative stress and inflammation.
Yu C, Zhang X, Wang R, Zhang C, Gao Y, Wang Y, Lv L, Wang Z, Zhang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157975
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157975
Parthenolide ameliorates inflammation in sepsis via covalently targeting Trim33 and inhibiting NF-κB pathway.
He X, Wang C, Zhang R, Wang Y, Zhang Y, Yang T, Zhang J, Rao S, Tang H, Peng X, Wang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157862
Huangqi Chifeng decoction alleviates cerebral ischemia and reperfusion injury by targeting NFKBIA, NF-κB1 p105 and PIAS1 to multi-dimensionally inhibit NF-κB/NLRP3 signaling: A multi-omics analysis.
Chen X, Ma X, Tang X, Lin W, Zheng Y, Zan J, Ding Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157801
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157801
PSAT1 Promotes NSCLC Progression via the De Novo Serine Synthesis Pathway and Represents a Therapeutic Vulnerability.
Zhou X, Zhao M, Cao Y, Zhou X, Wang K
Cancer medicine 2026 Apr;15(4):e71780
Cancer medicine 2026 Apr;15(4):e71780
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042
Cancer science 2026 Apr;117(4):1026-1042
Pathogenic mechanism of Eimeria tenella EtMIC2 promotes Eimeria tenella invasion and inhibits host cell apoptosis through binding to the ITGAV receptor.
Cui KL, Guo LL, Lei X, Chen YY, Liu KH, Duan BT, Zhang HH, Lv XL, Zheng MX
Poultry science 2026 Apr 9;105(7):106922
Poultry science 2026 Apr 9;105(7):106922
Repeated photobiological regulation therapy alleviates inflammation in mice with experimental acute pancreatitis through ROS/NF-κB pathway.
Nie F, Qi J, Hao S, Shi H, Hu Y, Ding Y, Han W
Lasers in medical science 2026 Apr 7;41(1)
Lasers in medical science 2026 Apr 7;41(1)
Lp-PLA2-derived LysoPC drives dendritic cell immunogenic activation and Th17 inflammation in severe asthma.
Wang F, Min Z, Qian Y, Gao J, Yang Z, Jiang Z, Chen Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 28;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 28;75(1)
Bovine serum albumin-coated metal-phenolic nanoplatform for atherosclerosis therapy via targeted delivery and inhibition of vascular smooth muscle cells proliferation.
Li N, Huang Q, Liu Y, Ren D, Liu Y, Liu X, Zhang P, Liu R
Free radical biology & medicine 2026 Apr 23;251:372-386
Free radical biology & medicine 2026 Apr 23;251:372-386
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
Liu Z, Zhang T, Wang S, Yin H, Shao X, Gao L, Lu X
Neurotoxicology 2026 Apr 21;114:103460
Neurotoxicology 2026 Apr 21;114:103460
ATF6 ameliorates renal warm ischemia-reperfusion injury through FHL2-mediated NF-κB signaling pathway.
Wu X, Shi JH, Bai Y, Yang DJ, Jia MY, Guo DF, Zhang JK, Shi XY, Zhang HP, Guo WZ, Zhang SJ
iScience 2026 Apr 17;29(4):115173
iScience 2026 Apr 17;29(4):115173
Metabolic Engineering of Commensal Bacteria for Producing 5-Hydroxyindoleacetic Acid as a Therapeutic Strategy for Colitis.
Du W, Zhang C, Zou ZP, Shan S, Wang LS, Jiang W, Yin BC, Ye BC, Zhou Y
ACS synthetic biology 2026 Apr 17;15(4):1412-1425
ACS synthetic biology 2026 Apr 17;15(4):1412-1425
Piezo2 Mediates a Vicious Cycle of "Mechanical Homeostasis Imbalance-Inflammation" in Sensory Nerves and the Cartilage Endplate.
Xu H, Geng W, Du Z, Du Y, Wu D, Tong B, Liang H, Zhou X, Ou Z, Wei J, Wang K, Song Y, Hua W, Xu Y, Ke W, Wang B, Yang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e07299
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e07299
Lithocarpus litseifolius and trilobatin ameliorate diabetic nephropathy through alleviating carbonyl stress by inhibiting AGEs/RAGE/NF-κB pathway.
Chen XM, Chen JX, Chen XM, Gao YX, Zeng CY, Chen DY, Xiang XQ, Hao XT, Wang SM, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158204
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 15;156:158204
Regulation of PSAT1 and PHGDH by m6A in endocrine-resistant breast cancer cells.
Piell KM, Vallarta A, Wilt AE, Avila-Valdes BL, Sumlut MH, Goli N, Petri BJ, He L, Zhang X, Clem BF, Klinge CM
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;:168266
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 15;:168266
A Pathological Microenvironment-Responsive Catalytic Carbon Nanodots Release Platform Intercepting the ROS-Inflammation Cascade to Alleviate Intervertebral Disc Degeneration.
Luo X, Xie J, Yan F, Peng Z, Pan C, Hu Y, Zhang J, Cai C, Yuan J, Li Y, Miao X, He D, Cheng X
Advanced healthcare materials 2026 Apr 14;:e71151
Advanced healthcare materials 2026 Apr 14;:e71151
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Cao XY, Tian JJ, Zhang W, Chen CL, Ma H
Neurochemical research 2026 Apr 10;51(2)
Neurochemical research 2026 Apr 10;51(2)
Zr-porphyrinic MOF PCN-224 enables sequential antibacterial and inflammation-modulating PDT for periodontitis.
Liu Q, Tang C, Liu J, Gao Y, Peng L
Colloids and surfaces. B, Biointerfaces 2026 Apr 10;265:115692
Colloids and surfaces. B, Biointerfaces 2026 Apr 10;265:115692
SRC-mediated phosphorylation of UBC9 regulates inflammatory and metabolic signaling in alcohol-associated liver disease.
Chandla S, Lim Y, Floris A, Mazarei M, Yang X, Tsuchiya T, Dagar M, Darmawan A, Justo M, Murali R, Gangi A, Tomasi I, Mavila N, Ramani K, Tomasi ML
Science advances 2026 Apr 10;12(15):eaec0138
Science advances 2026 Apr 10;12(15):eaec0138
LncRNA RP11-510J16.3 exacerbates sepsis-associated encephalopathy by facilitating NLRP3-dependent pyroptosis through miR-1290 sequestering.
Liu X, Xiao Y, Lai Y, Ding H, Wen Y, He Z, Chen M, Han Y, Jing Y, Wen M
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
H3K27ac-induced IFITM3 promotes progression of TNBC and resistance to anti-PD-1/PD-L1 therapy via the TNF-α/NF-κB/PD-L1 axis.
Li G, Fu B, Wang X, Lin H, Chen X, Zhang J
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 1;1872(6):168238
Ginsenoside Compound K Plays an Anti-Inflammatory Role in Gingival Epithelial Cells Stimulated With Porphyromonas gingivalis by Regulating Pyruvate Kinase M2.
Jin L, Lu L, Jiao Y, Wang Y, He H
Molecular oral microbiology 2026 Apr 1;
Molecular oral microbiology 2026 Apr 1;
PRMT1-Mediated PARP1 Methylation Drives Lung Metastasis and Chemoresistance via P65 Activation in Triple-Negative Breast Cancer.
Zhang J, Huang Z, Song C, Wu S, Xie J, Zou Y, Xie X, Wu T, Yang H, Tang H
Research (Washington, D.C.) 2025;8:0854
Research (Washington, D.C.) 2025;8:0854
Modulation of EGR1 Expression by Hyperglycemia in Swine Rotator Cuff Tendons.
Day J, Rajalekshmi R, Agrawal DK
Journal of orthopaedics and sports medicine 2025;7(3):337-344
Journal of orthopaedics and sports medicine 2025;7(3):337-344
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Lei X, Pan J, Deng K
Central-European journal of immunology 2025;50(3):276-289
Central-European journal of immunology 2025;50(3):276-289
Nephropathy II Decoction Attenuates Renal Fibrosis via Regulating TLR4 and Gut Microbiota Along the Gut-Kidney Axis.
Liu C, Gao Y, Chen Y, Zhu L, Rao F, Huang Y, Zeng Y, Cai R, Wang F, Cheng J
Biological & pharmaceutical bulletin 2025;48(5):577-594
Biological & pharmaceutical bulletin 2025;48(5):577-594
FR429 from Polygonum capitatum Demonstrates Potential as an Anti-hepatic Injury Agent by Modulating PI3K/Akt Signaling Pathway.
Yang Y, He L, He M, Zhang X, Liao S, Zeng Z, Lin Y, Tu B
Biological & pharmaceutical bulletin 2025;48(4):372-382
Biological & pharmaceutical bulletin 2025;48(4):372-382
Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis.
Lv D, Chu L, Du Y, Li C, Bao N, Su Y, Wang G, Zheng Y, Yu Y
Iranian journal of basic medical sciences 2025;28(2):237-244
Iranian journal of basic medical sciences 2025;28(2):237-244
Lactobacillus paracasei ZJUZ2-3 inhibits gastrointestinal tumors via the IAA-induced AHR/MTDH/NF-κB axis.
Yang R, Yang Y, Wu L, He K, Bi D, Teng L
International journal of biological sciences 2025;21(14):6522-6541
International journal of biological sciences 2025;21(14):6522-6541
SIRT4-Mediated Deacetylation of PRDX3 Attenuates Liver Ischemia Reperfusion Injury by Suppressing Ferroptosis.
Yu Q, Yang D, Ran B, Pan J, Song Y, Cui M, He Q, Mei C, Wang H, Li H, Li G, Meng Y, Wang F, Guo W, Zhu C, Chen S
International journal of biological sciences 2025;21(10):4663-4682
International journal of biological sciences 2025;21(10):4663-4682
Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways.
Huang J, Zhang J, Liu Z, Ma J, Wang Y, Wang F, Tang X
Mediators of inflammation 2025;2025:7468297
Mediators of inflammation 2025;2025:7468297
Shenlian Decoction Ameliorates LPS-Related Inflammation in db/db Mice: Coupling Network Pharmacology With Experimental Verification.
Liu YF, Liu YY, Xiao Y, Huang WJ, Sun RX, Hu J, Fu XZ, Tian CX, Fu Q, Zhao JX
Journal of diabetes research 2025;2025:3823051
Journal of diabetes research 2025;2025:3823051
Potential diagnostic markers and therapeutic targets for DM2 and periodontitis based on bioinformatics analysis.
Luo R, Liang Z, Chen H, Bao D, Lin X
PloS one 2025;20(4):e0320061
PloS one 2025;20(4):e0320061
TENS improves CFL injury rat and regulates the intestinal microbiota.
Miao M, Ma T, Chen R, Geng K, Shen Z, Sun Y
PloS one 2025;20(4):e0319592
PloS one 2025;20(4):e0319592
Xiao Qing Long Tang ameliorates neutrophil extracellular trap-dendritic cells-T helper 17 cell axis in Neutrophilic Asthma.
Ji X, Chen H, He SD, Huang M, You X, Xiao C, Chen Z, Cai J
PloS one 2025;20(11):e0336333
PloS one 2025;20(11):e0336333
SATB2 promotes humeral fracture healing in rats by activating the PI3K/AKT pathway.
Liu L, Rong S, Zhou X, Li H, Zhen K, Zheng C, Li K
Open life sciences 2025;20(1):20251126
Open life sciences 2025;20(1):20251126
GFPT2 promotes paclitaxel resistance in epithelial ovarian cancer cells via activating NF-κB signaling pathway.
Xu ZJ, Liu B, Li RN, Linghu H
Open life sciences 2025;20(1):20221039
Open life sciences 2025;20(1):20221039
17(R)-RvD1 Ameliorates Liver Injury in Hyperuricemia Through Inhibiting Pyroptosis via NF-κB Signaling Pathway.
Zhao L, Zhang Y, Qiao Y, Jia L, Luo S
Drug design, development and therapy 2025;19:6573-6585
Drug design, development and therapy 2025;19:6573-6585
Integrative Network Pharmacology and Transcriptomics Reveal the Mechanism of Gui-Qi-Yi-Shen Granules in the Treatment of IgA Nephropathy.
Cao JW, Tang YW, Jiang MY, Lu MD, Yang RC, Yu DR, Wan F
Drug design, development and therapy 2025;19:6269-6282
Drug design, development and therapy 2025;19:6269-6282
Lobetyolin Suppressed Osteoclastogenesis and Alleviated Bone Loss in Ovariectomy-Induced Osteoporosis via Hindering p50/p65 Nuclear Translocation and Downstream NFATc1/c-Fos Expression.
Xiu C, Luo H, Huang W, Fan S, Yuan C, Chen J, Xu C, Yao C, Hong D, Zhang L
Drug design, development and therapy 2025;19:4689-4715
Drug design, development and therapy 2025;19:4689-4715
Metabolism and Excretion of 8-O-Acetylharpagide in Rats and Identification of Its Potential Anti-Breast Cancer Active Metabolites.
Zhao X, Su S, Zhou J, Gao J, Tang X, Wen B
Drug design, development and therapy 2025;19:2795-2815
Drug design, development and therapy 2025;19:2795-2815
Network Pharmacology and Experimental Verification: Phellodendri Chinensis Cortex-Cnidii Fructus Herb Pair Alleviates Atopic Dermatitis by Regulating the TLR4/NF-κB Pathway.
Liu X, Chen L, Sun P, Jiang X, Li P, Xu Z, Zhan Z, Wang J
Drug design, development and therapy 2025;19:1451-1474
Drug design, development and therapy 2025;19:1451-1474
Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways.
Zhu D, Wu XY, Li LC
International journal of ophthalmology 2025;18(8):1426-1432
International journal of ophthalmology 2025;18(8):1426-1432
Enhancement of retinal Müller glia's phagocytic activity against hard exudates by conbercept via activation of PPARγ-CD36 axis in diabetic retinopathy.
Zhu YY, Qin SY, Xie H, Liu YP, Li XS, Zhang CY, Zhang YC, Zhang JF
International journal of ophthalmology 2025;18(7):1252-1261
International journal of ophthalmology 2025;18(7):1252-1261
Hylotelephium mingjinianum Extract Attenuates Oxidative Stress and Inflammation in Experimental Periodontitis.
Yuan L, Kong C, Shi N, Chen J, Zhang T, Wang X
Journal of inflammation research 2025;18:8263-8276
Journal of inflammation research 2025;18:8263-8276
Isoliquiritigenin Alleviates Periodontitis by Suppressing Inflammation via NF-κB Signaling Pathway of Immune Cell.
Wang X, Zhao T, Liang B, Fang J, Dong Q, Chen Q
Journal of inflammation research 2025;18:6133-6148
Journal of inflammation research 2025;18:6133-6148
COMMD1 Regulates Osteoclast Differentiation in Talaromyces marneffei-Induced Osteomyelitis via the NF-κB Pathway.
Zhang Y, Yang F, Zhao W, Wei R, Zeng G, Zong S
Infection and drug resistance 2025;18:6079-6092
Infection and drug resistance 2025;18:6079-6092
LT-α Facilitates the Aerobic Glycolysis and M1 Polarization of Macrophages by Activating the NF-κB Signaling Pathway in Intervertebral Disc Degeneration.
Qiu C, Guo Z, Yuan J, Xiang H, Chen B, Yi Y, Zhao Y
Journal of inflammation research 2025;18:4103-4120
Journal of inflammation research 2025;18:4103-4120
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
Hu ZQ, Ma R, Sun JQ, Peng M, Yuan J, Lai N, Liu J, Xia D
Journal of inflammation research 2025;18:3555-3570
Journal of inflammation research 2025;18:3555-3570
Fu-Fang-Qi-Di-Hua-Yu-Tang Improves Diabetic Macrovascular Disease via PI3K/AKT Pathway Regulation.
Zhang S, Yan M, Liang P, Zhang Y, Liu J, Huang H, Li G, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:2247-2265
Serum Exosomes miR-122-5P Induces Hepatic and Renal Injury in Septic Rats by Regulating TAK1/SIRT1 Pathway.
Wang J, Jiang Y, Yuan Y, Ma X, Li T, Lv Y, Zhang J, Chen L, Zhou J, Meng Y, Zhang B, Dong X, Ma L
Infection and drug resistance 2025;18:185-197
Infection and drug resistance 2025;18:185-197
Kushe Tincture Ameliorates DNCB-Induced Atopic Dermatitis by Affecting NF-Kb/JAK-STAT3 Pathway: Bioinformatics Analysis and Animal Experiment Verification.
Feng H, Zhou Y, Ren X, Zhu X, Duan X, Qu S, Zhu B, Li Y, Qin Y
Journal of inflammation research 2025;18:15293-15308
Journal of inflammation research 2025;18:15293-15308
ZnO NPs Attenuate LPS-Induced Inflammation in RAW264.7 Macrophages by Inhibiting NF-κB and JAK1-STAT1/STAT3 Pathways and Reducing ROS.
Tang H, Zhang L, Deng C, Li Y, Ren G, Sun Z, Chang L, Xu M, Xiao D, Zhang H
Journal of inflammation research 2025;18:14075-14096
Journal of inflammation research 2025;18:14075-14096
Electroacupuncture Regulates Oxidative Stress-Mediated NLRP3/ASC/Caspase-1 Pathway to Inhibit Microglial Activation: Alleviating Neuroinflammation and Depression in IBD.
Li Z, Cao S, Yang J, Chen L, Jia L, Lu P, Liu J, Liu M, Liu Q
Journal of inflammation research 2025;18:11935-11950
Journal of inflammation research 2025;18:11935-11950
ADAMTS7 Enhances Gastric Cancer Growth and Metastasis by Triggering the NF-κB Signaling Pathway.
Chen S, He J, Gao H, Gao X, Dai L, Chen J, Sha Z
Journal of Cancer 2025;16(3):1008-1019
Journal of Cancer 2025;16(3):1008-1019
γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway.
Wei J, Xie J, He Z, Feng X
Frontiers in pharmacology 2025;16:1742401
Frontiers in pharmacology 2025;16:1742401
NETs drive myocardial fibrosis in hypertension via an NF-κB/ferroptosis axis.
Tu Q, Gong X, Yuan X, Tang Y, Huang R, Jiang Q, Li W
Frontiers in immunology 2025;16:1712786
Frontiers in immunology 2025;16:1712786
IL-18 receptor axis in allergic conjunctivitis: a multi-omics study.
Yuan L, Su W, Li L, Xiang Y, Xu Z, Wang Y, Hua X, Yuan X
Frontiers in immunology 2025;16:1704591
Frontiers in immunology 2025;16:1704591
Xin-Fu-Kang oral liquid improves cardiac function and attenuates miR-223-associated NF-κB/NLRP3 pyroptotic signaling in chronic heart failure.
Ye Z, Liu M, Zhang X, Wu H, Qiu Z, Chai R, Hu Y
Frontiers in pharmacology 2025;16:1697422
Frontiers in pharmacology 2025;16:1697422
LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.
Zhao R, Wang L, Zhou Y, Xiao K, Liu Q, Yu K
Frontiers in immunology 2025;16:1650984
Frontiers in immunology 2025;16:1650984
Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance proteins.
Aksüt Y, Şengelen A, Gürsoy DM, Öğütcü İ, Kuvet Ö, Pekmez M
Frontiers in pharmacology 2025;16:1643186
Frontiers in pharmacology 2025;16:1643186
Isodon lophanthoides alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis.
Chen K, Liang J, Tan Y, Li Y, Pan X, Guo Z, Zhang W, Sun Z
Frontiers in pharmacology 2025;16:1630927
Frontiers in pharmacology 2025;16:1630927
Jianpi-Huayu-Jiedu formula improves metabolic dysfunction-associated steatohepatitis through ameliorateing hepatic oxidative stress and lipid accumulation in vivo and in vitro.
Wu X, Chen T, Zhang Z, Wang D, Zhou K, Li J, Xu L, Meng C, Pan H, Huang J, Gao Y, Li S
Frontiers in pharmacology 2025;16:1612726
Frontiers in pharmacology 2025;16:1612726
Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout.
Yuan Y, Gao Z, Chen J, Liu Y, Zhou J
Frontiers in genetics 2025;16:1598835
Frontiers in genetics 2025;16:1598835
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Chen H, Li G, Deng L, Xu N, Lee SM, Nie X, Bian JS
Frontiers in pharmacology 2025;16:1585181
Frontiers in pharmacology 2025;16:1585181
Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model.
Wu J, Xie W, Xie Y, Mazhar M, Duan J
Frontiers in pharmacology 2025;16:1573693
Frontiers in pharmacology 2025;16:1573693
Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3.
Song J, Huang X, Luo Y, Li M, Ouyang Y, Liu W, Pan H, Luo H
Frontiers in immunology 2025;16:1563602
Frontiers in immunology 2025;16:1563602
Umbilical cord stem cells therapy against bacterial pneumonia based on zebrafish pneumonia model.
Chen X, Jin J, Chen X, Wu Y, Guo Y, Qian Z, Huang H
Frontiers in pharmacology 2025;16:1546193
Frontiers in pharmacology 2025;16:1546193
Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.
Li D, Li Y, Yang S, Zhang X, Cao Y, Zhao R, Zhao Y, Jin X, Lu J, Wang X, Wang Q, Liu L, Wu M
Frontiers in pharmacology 2025;16:1515485
Frontiers in pharmacology 2025;16:1515485
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Zheng L, Zhao B, Ji R, Zhang Z, Liu Y, Zhao X, Cai J, Qiao T
Frontiers in pharmacology 2025;16:1509860
Frontiers in pharmacology 2025;16:1509860
Curdione combined with borneol treats bacterial mixed HPV infection by regulating the crosstalk among immune cells.
Liu J, Shu T, Mu Y, Zheng W, Lu X, Tao H
Frontiers in immunology 2025;16:1503355
Frontiers in immunology 2025;16:1503355
Mn(3)O(4) nanozyme-based anti-inflammatory therapy modulates microglial phenotype by downregulating TLR4/NOX2 expression and further alleviates Alzheimer's disease pathology.
Xie J, Cao K, Liu L, Zhang L, Yang Y, Gong H, Luo H
Theranostics 2025;15(15):7467-7488
Theranostics 2025;15(15):7467-7488
Qing-Re-Hua-Shi Decoction ameliorates DSS-induced colitis by modulating multiple signaling pathways and remodeling the gut microbiota and metabolite profile.
Chen W, Xu L, Wang L, Shan YN, Li Y, Zhu JS
Frontiers in cellular and infection microbiology 2025;15:1541289
Frontiers in cellular and infection microbiology 2025;15:1541289
Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1-Nrf2 axis.
Hou R, Jiang B, Wang K, Yang X, Zhang W
Frontiers in molecular biosciences 2025;12:1686436
Frontiers in molecular biosciences 2025;12:1686436
Multi-targeted inhibition of NF-κB signaling underlies the anti-osteoarthritic effects of BGJXF and its key component dehydrocorydaline.
Shen J, Bin Z, Shen Y, Xie F, Zhang X, Tan X, Xu H
Frontiers in medicine 2025;12:1676071
Frontiers in medicine 2025;12:1676071
Potential mechanisms of zinc sulfate in inhibiting porcine reproductive and respiratory syndrome virus replication: attenuation of oxidative stress, inflammatory response, and apoptosis.
Yang H, Zhang C, Li Q, Wu Z, Sun N, Yin W, Fan K, Li H
Frontiers in veterinary science 2025;12:1663508
Frontiers in veterinary science 2025;12:1663508
TRPM2-mediated feed-forward loop promotes chondrocyte damage in osteoarthritis via calcium-cGAS-STING-NF-κB pathway.
Sun K, Zhang X, Hou L, Lu F, Liu H, Zheng Z, Guo Z, Xu J, Ruan Z, Hou Y, He J, Guo F, Yang K
Journal of advanced research 2025 Sep;75:213-227
Journal of advanced research 2025 Sep;75:213-227
JOSD2 alleviates acute kidney injury through deubiquitinating SIRT7 and negativity regulating SIRT7-NF-κB inflammatory pathway in renal tubular epithelial cells.
Zhao Y, Zhao QQ, Fan SJ, Xu DY, Lin LM, Luo W, Ye BZ, Zou CP, Zhu H, Zhuang ZS, Zhao YJ, Liang G
Acta pharmacologica Sinica 2025 Sep;46(9):2468-2481
Acta pharmacologica Sinica 2025 Sep;46(9):2468-2481
Influence and molecular mechanism of cinnamaldehyde against ventricular arrhythmia via the TAK1-p38MAPK-NLRP3 pathway.
Ma G, Li M, Yang W, Wang H, Tian X, Yin Y, Tang Y, Liang W
Heart and vessels 2025 Sep;40(9):846-861
Heart and vessels 2025 Sep;40(9):846-861
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Zhang B, Yu C, Zhang S, Zhang M
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Regulation of macrophage phenotypes via NF-κB/NLRP3 and HIF1α/p53 pathways by fuco-galactoglucan from Agrocybe aegerita.
Li X, Shui M, Zhang X, Tang H, Guo H, Gu F, Xu H, Han B, Kou Y
International journal of biological macromolecules 2025 Sep;322(Pt 2):146559
International journal of biological macromolecules 2025 Sep;322(Pt 2):146559
Resveratrol alleviates lipopolysaccharide-induced acute lung injury through blocking the excessive autophagy/mitophagy via SIRT1/PGC-1α and TNF/NF-κB/JNK pathways.
Li H, Wang X, Deng Y, Liu M, Li W, Wang J, Zeng C, Dai H
International journal of biological macromolecules 2025 Sep;321(Pt 3):146500
International journal of biological macromolecules 2025 Sep;321(Pt 3):146500
The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25.
Yuan S, Bacchetti R, Adams J, Cuffaro D, Rossello A, Nuti E, Santamaria S, Rainero E
The FEBS journal 2025 Sep;292(17):4491-4515
The FEBS journal 2025 Sep;292(17):4491-4515
Insufficient BK channel function enhances NF-κB nuclear translocation and promotes IL-6 synthesis in vascular smooth muscle cells induced by AT1-AA.
Li Y, Xue L, Feng J, Wang Z, Long Y, Liu W, Zhang S, Zhi X, Hao H, Wang X, Liu H, Wang L
Biochemical pharmacology 2025 Sep;239:117000
Biochemical pharmacology 2025 Sep;239:117000
Hypoxia-Inducible Factor-1α-Induced Astrocytic D-Dopachrome Tautomerase Activates Microglial Inflammatory Response following Spinal Cord Injury.
Li A, Li M, Xu S, Niu L, Li S, Zhou Y, Cao Z, Cai R, He B, Guo A, Li A, Song H, Wang Y, Wang Y
The American journal of pathology 2025 Sep;195(9):1676-1692
The American journal of pathology 2025 Sep;195(9):1676-1692
The mechanism of action in Mussaenda pubescens (Yuye Jinhua) against influenza A virus: Evidence from in vitro and in vivo studies.
Zhang J, Wu B, Yang N, Lin X, Chen M, Chang H, Shi Y, Lin X, Li G, Dai W, Li C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157070
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157070
Multi-omics analyses reveal that hesperidin ameliorates high-altitude pulmonary hypertension by restoring gut-lung axis homeostasis.
Fang L, Yang T, Nijiati Y, Shahanati D, Abudukeremu A, Li J, Shi W, Maimaitiyiming D, Aikemu A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157069
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157069
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Wen Y, Li M, Hao Y, Peng J, Wei X, Zhang Z, Liu B, Wang Y, Peng T, Ma Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Donkey Milk Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis by Protecting Gut Barrier Function, Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway, and Modulating Gut Microbiota.
Yang L, Ni H, Gou X, Zhong B, Wen K, Zhang Y, Zhang S, Wang Y
Food science & nutrition 2025 Sep;13(9):e70989
Food science & nutrition 2025 Sep;13(9):e70989
Flavonoids in Rosa roxburghii Tratt Fermentation Broth Ameliorate Obesity via DNMT3a/SIRT1-Mediated Epigenetic Modulation.
Liu M, Li H, Zhang J, Zhong Y, Huang C, Zhu L, Hu Z, Xu Y, Zhao S, Pan W
Food science & nutrition 2025 Sep;13(9):e70892
Food science & nutrition 2025 Sep;13(9):e70892
Effect of temperature on acute kidney injury in a rat model of renal ischemia‒reperfusion.
Mei J, Xie M, Dai C, Tang Y, Huang N, Ou J
Cryobiology 2025 Sep;120:105276
Cryobiology 2025 Sep;120:105276
H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD-1 Blockade.
Zhou Y, Zhao W, Zhu Y, Liu H, Sun Y, Gong Z, Li X, Liu Z, Wen K, Wang Y, Ren J, Xiao R, Jiang L, Hu Y, Bi E, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08095
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08095
Rhapontigenin attenuates neurodegeneration in a parkinson's disease model by downregulating mtDNA-cGAS-STING-NF-κB-mediated neuroinflammation via PINK1/DRP1-dependent microglial mitophagy.
Su Z, Shu H, Huang X, Ding L, Liang F, Xu Z, Zhu Z, Chen M, Wang X, Li G, Xia H, Cao Q, Zhang W, Xu P, Yang X
Cellular and molecular life sciences : CMLS 2025 Sep 6;82(1):337
Cellular and molecular life sciences : CMLS 2025 Sep 6;82(1):337
DCAAA mitigates neuroinflammation and microglial pyroptosis in spinal cord injury by inhibiting PI3K/AKT/NF-κB and NLRP3/caspase-1/GSDMD signaling.
Gao J, Liu Y, Li R, Liu Y, Qi Z, Zhang Z
European journal of pharmacology 2025 Sep 5;1002:177816
European journal of pharmacology 2025 Sep 5;1002:177816
ANXA4 Alleviates Cardiomyocyte Injury Associated With Ischemia-Reperfusion by Interfering With NFκB p50's Transcriptional Activation of RAGE.
Zhao Z, Zhao Y, Zang X, Ren Y, Song W, Wang L, Chen K, Liang E, Zhou Y, Wang X, Niu K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71033
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e71033
Garlic essential oil alleviate oxidative stress, inflammation and microbiota dybiosis from small intestinal damage in lipopolysaccharide-challenged weaned piglets.
Chen Y, Song W, Sun C, Chen Y, Chen X, Chen S, Chen Q, Wang K
Porcine health management 2025 Sep 30;11(1):48
Porcine health management 2025 Sep 30;11(1):48
Yak milk ameliorates chronic alcohol-induced brain injury in mice by modulating the gut microbiota and suppressing the TLR4/NF-κB pathway.
Liang Z, Liu Q, Wang M, Gong D, Qin M, Li H, Huang X, Wang Y, Long D
Food & function 2025 Sep 29;16(19):7880-7899
Food & function 2025 Sep 29;16(19):7880-7899
Nicotinamide metabolic dysregulation plays a key role in Benzo[a]pyrene-induced adverse birth outcomes: Evidence from multi-omics profiling, experimental and epidemiological validation.
Zhao N, Song W, Sun T, Wu W, Feng Y, Ma N, Wang S
Journal of hazardous materials 2025 Sep 28;498:140000
Journal of hazardous materials 2025 Sep 28;498:140000
Fucoxanthin ameliorates high-fat diet-induced kidney injury in mice.
Liu Z, Xu B, Zheng J, Tian Y, Yang Z, Shi H
The British journal of nutrition 2025 Sep 28;134(6):441-450
The British journal of nutrition 2025 Sep 28;134(6):441-450
A Novel Function of Glycerol Kinase Alleviates LPS-Induced Inflammatory Responses by the p38/STAT3 Pathway and Mitigates ROS Generation in Kupffer Cells.
Li Y, Zhang X, Wang D, Fan G, Yang X
Antioxidants (Basel, Switzerland) 2025 Sep 26;14(10)
Antioxidants (Basel, Switzerland) 2025 Sep 26;14(10)
Systematic reevaluation on the antipyretic, analgesic effects, and uncover the mechanisms of Chaiqin Qingning capsule, a traditional Chinese medicine, via establishing lipopolysaccharide - induced fever models, physical and chemical - stimuli pain models.
Huang L, Gao H, Halihaman B, Li C, Ding X
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120432
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120432
Penthorum chinense Pursh extract ameliorates lupus nephritis disease in MRL/lpr mice via the PPARγ/NFκB signaling axis.
Li Y, Hua Y, Xin X, He W, Xu L, Ding B, Huang Q, Fan Y, Tian F, Ji J
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120379
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120379
Atractylenolide III attenuates acute kidney injury through phosphorylation of PIK3CA: Functional activation and molecular interaction analysis.
You J, Sun S, Lv D, Fan S, Yan X, Liu M, Jin J, Wang W
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120368
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120368
Platycodon grandiflorum: A promising medicinal and food homologous plant for cigarette smoke-induced chronic bronchitis.
Sun J, Wang X, Chang X, Huang Y, Zha L, Zhi N, Wang J, Peng D, Xia Q, Hu J, Pang X, Liang X, Jin C, Gui S
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120381
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120381
Protective effect and mechanism of Zhuang medicine Tinosporae Radix on LPS-induced neuroinflammation.
Wang J, Xie Y, Wang S, Chen L, Wu L, Hu Z, Deng J, Wu Z, Wang Y, Wang S, Huang L
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120276
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120276
Prunella vulgaris seed oil alleviates cancer related fatigue through hypothalamic inflammation and CRH regulation.
Wu C, Hu Q, Han M, Peng Y, Zhang C, Wu Z, Liu R, Xing S, Yin Y, Deli MA, Zhang H, Chen G
NPJ science of food 2025 Sep 24;9(1):194
NPJ science of food 2025 Sep 24;9(1):194
Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands.
Zhang W, Qi D, Pei X, Lu D, Ba M, Xuan S, Huang D, Yang T, Yang J, Li Z, Huang S
Journal of nanobiotechnology 2025 Sep 2;23(1):600
Journal of nanobiotechnology 2025 Sep 2;23(1):600
Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation.
Li T, Yao Z, Huang Y, Li R, Zhang L, Chen R, Gu W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70980
Astaxanthin attenuates AFB1-induced hepatotoxicity by activating Nrf2 and inhibiting the NF-κB signaling pathway.
Kang K, Zhang Y, Xie W, Ma W, Chen J, Chen Z
Ecotoxicology and environmental safety 2025 Sep 15;303:119025
Ecotoxicology and environmental safety 2025 Sep 15;303:119025
Tetrabromophthalate bis(2-ethylhexyl) ester (TBPH) exposure induces renal inflammation injury by activating MAVS-IRF3 signaling pathway in vitro and in vivo models.
Xing B, Lan H, Li H
Ecotoxicology and environmental safety 2025 Sep 15;303:118920
Ecotoxicology and environmental safety 2025 Sep 15;303:118920
Ginsenoside F4 inhibits colorectal cancer progression by boosting dendritic cell maturation and remodeling the tumor microenvironment.
Xie W, Li XJ, Zhong YS, Fang J, Qi H, Yang M, Ying HZ, Yu CH
World journal of gastrointestinal oncology 2025 Sep 15;17(9):108892
World journal of gastrointestinal oncology 2025 Sep 15;17(9):108892
A hydrogel-based drug delivery system reduces inflammation and oxidative stress to alleviate intervertebral disc degeneration.
Wang S, Zhai Y, Liu M, Cheng Z, Zhang J, Zhang H, Wang H, Hu Y, Li C, Luo Z
Acta biomaterialia 2025 Sep 1;203:229-244
Acta biomaterialia 2025 Sep 1;203:229-244
Porcine GWAS identifies ACOT11 as regulator for macrophage IL-1β maturation via IFNGR2 palmitoylation.
Zhang M, Liu S, Wu Z, Wang C, Zhang H, Yang J, Guo C, Dai M, Wang X, Ren W
Science China. Life sciences 2025 Oct;68(10):3037-3050
Science China. Life sciences 2025 Oct;68(10):3037-3050
L-selectin Promotes Migration, Invasion and Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via NF-kB Signaling Pathway.
Wu W, Cheng Z, Nan Y, Pan G, Wang Y
Inflammation 2025 Oct;48(5):2960-2972
Inflammation 2025 Oct;48(5):2960-2972
Neutrophils loaded NAD(+) impede TLR4/NF-κB/NLRP3 pathway for sepsis treatment.
Zhao Y, Qu Y, Huang C, Li C, Zhang W, Wang X, Duan W, He Q, Zhang Y, Jiao J, Zheng R
Materials today. Bio 2025 Oct;34:102168
Materials today. Bio 2025 Oct;34:102168
Activation of the TLR2/NF-κB signaling axis by capsid proteinVP1 of feline calicivirus promotes IL-1β expression in vitro.
Liu J, Zhao S, Liu S, Guo Y, Zhang S, Bao D, Wei Y, Niu J, Yi S, Shao H, Dong H, Wang K, Hu G
Veterinary microbiology 2025 Oct;309:110693
Veterinary microbiology 2025 Oct;309:110693
African swine fever virus pMGF505-9R enhances RIG-I-like receptor signaling by promoting RING finger protein 125 autoubiquitination.
Zhao J, Zhang X, Mou C, Shi K, Chen Z
The Journal of biological chemistry 2025 Oct;301(10):110669
The Journal of biological chemistry 2025 Oct;301(10):110669
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Liu K, Huang Y, Xiao W, Liao J, Ouyang S, Liang Y, Fu J
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Crosstalk between YAP-TEAD and PPAR suppresses HIV-1 LTR transcription in vitro.
Zhou C, Liu X, He H, Wu Z, Liu Y, Rashid HK, Li L
Biochemical pharmacology 2025 Oct;240:117109
Biochemical pharmacology 2025 Oct;240:117109
Research on the Pharmacodynamic Substances and Mechanism of Action of Tibetan Medicine Liuwei Muxiang Powder in the Treatment of Ethanol-Induced Gastric Ulcer Model of GES1 Cell.
Lu H, Zhang T, Liang J, Zeng J, He J, Zhu J, Yuan J, Fu X, Li H, Zhong G
Chemistry & biodiversity 2025 Oct;22(10):e00722
Chemistry & biodiversity 2025 Oct;22(10):e00722
Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection.
Zhao H, Zhang Y, Han Q, Li H, Liu W, Sun L, Shang Y
PLoS pathogens 2025 Oct;21(10):e1013623
PLoS pathogens 2025 Oct;21(10):e1013623
5-HT regulates resistance to aumolertinib by attenuating ferroptosis in lung adenocarcinoma.
Feng Y, He Y, Zuo R, Gong W, Gao Y, Wang Y, Wang Y, Chen W, Chen L, Luo Y, Yuan D, Chen P, Guo H
EMBO molecular medicine 2025 Oct;17(10):2586-2611
EMBO molecular medicine 2025 Oct;17(10):2586-2611
Unlocking the gut-lung axis: Feixin decoction as a novel modulator in hypoxic pulmonary hypertension.
Wang FY, Yi J, Zhou LL, Tan JL, Cao XY, Zhang C, Wan JJ, Song L, Dai AG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157118
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157118
Removal and toxic intervention of polystyrene microplastics and nanoplastics by magnetic nano-Fe(3)O(4) in spermatogonial GC-1 cells.
Cheng C, Cui Y, Wang Y, Huang J, Ma J, Luo T, Chen W
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109020
Reproductive toxicology (Elmsford, N.Y.) 2025 Oct;137:109020
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway.
Xu W, Ou D, Zhao Y, Liu Y, Yan P, Li S, Sun Q, Zhang X, Liu H, Huang J, Fang Y
Cellular signalling 2025 Oct;134:111909
Cellular signalling 2025 Oct;134:111909
Shikonin Ameliorates Alcohol-Associated Liver Disease by Reducing Oxidative Stress, Apoptosis, and Inflammation.
Gan H, Gong M, Wang L, Huang X, Chen Y, Hu Z, Li X, Zeng Q
Food science & nutrition 2025 Oct;13(10):e71064
Food science & nutrition 2025 Oct;13(10):e71064
Role of SLC16A10 in Psoriasis Through the Regulation of Arachidonic Acid Metabolism in Keratinocytes.
Yang J, Chen Y, Li B, Wu S, Liang H, Yang X, Li X, Sun P, Guo G, Li T, Jia Y, Li H, Bai M, Xu J, Liu Z, Liu W, Jiang X, Cai H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e17093
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e17093
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds.
Gong M, Du Z, Gong T, Wang Y, Yin C, Sun B, Liu Z, Chen L, Liao Z, Wang W, Zhao T, Wang Y, Dong Y, Wang K, Ma M, Li W, Li J, Li H, Lin C, Zhang Y, Liu Y, Liu X, Ban T, Bao H, Zhang Y, Zhang Y, Li Z, Jiao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e03098
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e03098
TGF-β3-mediated phagocytosis protects mammary epithelial cells of ketotic dairy cows against metabolic stress-induced inflammatory damage.
Chang R, Jia H, Chen Y, Loor JJ, Xu Q, Ma L, Li M, Shen T, Li X, Xu C, Sun X
Journal of dairy science 2025 Oct;108(10):11443-11462
Journal of dairy science 2025 Oct;108(10):11443-11462
Potential Mechanism of Qiju Dihuang Pill in Treating Primary Sjogren's Syndrome Revealed by Network Pharmacology and Experimental Verification.
Wang H, Cheng H, Li M, Zhu X, Wang X
Chemical biology & drug design 2025 Oct;106(4):e70186
Chemical biology & drug design 2025 Oct;106(4):e70186
EOAI3402143 inhibits lung adenocarcinoma progression through the NF-κB/NR4A1 pathway.
Xu J, Liu W, Chen L, Zhang J, Zhang D, Huang H, Zhang X, Huang X, Zhang G
Acta biochimica et biophysica Sinica 2025 Oct 9;58(4):833-44
Acta biochimica et biophysica Sinica 2025 Oct 9;58(4):833-44
ADAP-METTL3 modulates the inflammatory responses of macrophages via m(6)A modification of Spry1.
Dong A, Zhang P, Yang F, Wang Y, Liu H
Cell death & disease 2025 Oct 7;16(1):708
Cell death & disease 2025 Oct 7;16(1):708
Gut microbiota dysbiosis exacerbates post-stroke depression via microglial NLRP3 inflammasome activation.
Chen Y, Yu L, Zhang L, Liu C, You Y, Guo H, Li Z, Yin X, Hong T, Ding L, Fang Q
Experimental neurology 2025 Oct 4;395:115488
Experimental neurology 2025 Oct 4;395:115488
Multi-omics and network pharmacology approaches reveal the mechanism of action of KeKe tablet against post-infectious cough.
Su M, Zhang J, Wang S, Chen W, Lai M, Peng L, Liang Y, Feng Y, Zhou H, Qiao W, Sun P
Chinese medicine 2025 Oct 4;20(1):160
Chinese medicine 2025 Oct 4;20(1):160
A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis.
Huang H, Tang M, Hu P, Zhan Y, Sun W, Zheng W, Zhu J, Chen J, Xue S, Huang S, Han W, Zhang C, Ding C, Zhang Y, Li S, Ruan G
Journal of nanobiotechnology 2025 Oct 31;23(1):695
Journal of nanobiotechnology 2025 Oct 31;23(1):695
Yiqi Wenyang Formula ameliorates diabetic kidney disease via inhibiting inflammation and regulating the gut microbiota-bile acid axis in mice by FXR signaling pathway.
Yuan T, Gao X, Wang X, Tang X, Liang Z, Yin Y, Liu S, Ou J, Su W, Zhang Z, Li X, Huang Q, Zhao D, Zhang H
Chinese medicine 2025 Oct 30;20(1):183
Chinese medicine 2025 Oct 30;20(1):183
Arginyl-fructosyl-glucose (AFG), a major Maillard reaction product of red ginseng, improved kidney and pancreatic injury in vitro and in vivo in type 2 diabetes mellitus.
Tsopmejio ISN, Tang S, Gao XF, Liu Z, Li XD, Qi MH, Zhu HY, Wang Z, Li W
International immunopharmacology 2025 Oct 30;164:115378
International immunopharmacology 2025 Oct 30;164:115378
Strand-specific functions of miR-301a-3p and -5p drive opposing roles in pancreatic cancer via ferroptosis and pyroptosis.
Chen Y, Dai S, Cai W, Zhao J, Zhang F, Cheng CS, Chen L
Cell biology and toxicology 2025 Oct 28;41(1):145
Cell biology and toxicology 2025 Oct 28;41(1):145
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Zhao W, Wang H, Peng S, Wei Q, Zhang L, Li Y, Yang W
Chinese medicine 2025 Oct 23;20(1):178
Chinese medicine 2025 Oct 23;20(1):178
A Therapeutic System Regulating Iron Metabolism in CD63(+) Macrophage Subsets Activates Anti-tumor Immunity for Bone Metastasis Therapy.
Xue Y, Wang S, Yin Y, Chai X, Zhou Z, Li H, Mou H, Wang F, Yao M, Zhao S, Lei J, Jin L, Fang M, Chen F, Li Z, Sun Y, Xu Y, Li H, Xu J, Zhang N
ACS nano 2025 Oct 21;19(41):36544-36565
ACS nano 2025 Oct 21;19(41):36544-36565
Activation of Sirtuin3 by 6,4'-Dihydroxy-7-methoxyflavanone Against Myoblasts Senescence by Attenuating D-Galactose-Induced Oxidative Stress and Inflammation.
Li B, Gu Y, Zhou L, Chen R, Liu Y, Wan Z, Liang Z, Wang Y, Ji R, Liu Z
Nutrients 2025 Oct 20;17(20)
Nutrients 2025 Oct 20;17(20)
Alpinetin Alleviates Cardiac Inflammation and Remodeling via TLR4/MyD88/NF-κB Signaling Pathway in Rats with Acute Myocardial Infarction.
Feng M, Chen X, Huang F, Chen L, Liu C, Li W, Li Y, Chen S, Deng Z, Wei Z, Luo Y, Yu X, Qin A
International journal of molecular sciences 2025 Oct 16;26(20)
International journal of molecular sciences 2025 Oct 16;26(20)
Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation.
Yang N, Li Y, Zhang J, Gao X, Zhang P, Li W
European journal of medical research 2025 Oct 15;30(1):975
European journal of medical research 2025 Oct 15;30(1):975
Ginsenoside Rb3 modulates gut microbiota to alleviate cerebral inflammation and ferroptosis via the NLRP3/NF-κB/GPX4 pathway in rats with cerebral ischemia/reperfusion injury.
Xie X, Ge W, Luo Y, Xing X, Sun X
European journal of pharmacology 2025 Oct 15;1005:178091
European journal of pharmacology 2025 Oct 15;1005:178091
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Yu X, Li X, Wang Y, Yu X, Guo X, Wang C, Wang F
International immunopharmacology 2025 Oct 10;163:115255
International immunopharmacology 2025 Oct 10;163:115255
Thrombopoietin mitigates neuronal death by enhancing mitophagy and suppressing NLRP3 inflammasome activation under oxygen-glucose deprivation conditions.
Li L, Zhang Y, Zhong J, Kong H, Liu Y, Chen H, Fang X, Zhong Z, Xue H, Yang M, Chen C
American journal of physiology. Cell physiology 2025 Oct 1;329(4):C1173-C1187
American journal of physiology. Cell physiology 2025 Oct 1;329(4):C1173-C1187
Dexmedetomidine regulates sleep rhythm and alleviates neuroinflammation in rats under high-altitude hypoxia.
Liu S, Feng L, Yang H, Liu Y, Sun W, Liu Y, Xu L
Journal of physiology and biochemistry 2025 Nov;81(4):1125-1141
Journal of physiology and biochemistry 2025 Nov;81(4):1125-1141
MTFR1 Promotes Proliferation and Metastasis of Triple-Negative Breast Cancer by Regulating Mitochondrial Metabolism.
Zhu Z, Wang J, Liu J, Sun G
IUBMB life 2025 Nov;77(11):e70054
IUBMB life 2025 Nov;77(11):e70054
Identification of an IL17RC missense variant in a Chinese family with multiple osteochondromas and ankylosing spondylitis.
Zheng Y, Wei X, Gan Z, Zhang M, Shen Z, Ma S, Huang Y, He F, Wang J, Xiong F
Journal of human genetics 2025 Nov;70(11):557-564
Journal of human genetics 2025 Nov;70(11):557-564
Sorafenib induces intestinal toxicity by disturbing gut microbiota and activating the LPS/TLR4/NF-κB signaling pathway in mice.
Xu Y, Mo Y, Zhou W, Qin M, Li M, Yin G, Yu H, Chen Y, Du H, Jin Y, Huang H, Ma C, Xia J, Li H, Xie Z, Wang P, Hong Y
Toxicology 2025 Nov;517:154220
Toxicology 2025 Nov;517:154220
Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1.
Si W, Wang CL, Zeng LH, Zhao QY, Xie YT, Yang Y, Diao HT, Song JL, Wu H, Zhang F, Wang Z, Kong X, Jiang WT, Zhang XY, Lin KY, Yao FT, Xiong YT, Pan TF, Pang P, Yang BF, Bian Y
Acta pharmacologica Sinica 2025 Nov;46(11):2924-2937
Acta pharmacologica Sinica 2025 Nov;46(11):2924-2937
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Ding X, Han X, Zhang Y, Zhang Y, Li F, Wang J
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Hesperidin Inhibits Oxidative Stress and Apoptosis of Granulosa Cells in Polycystic Ovarian Syndrome Through the JAK2/STAT3 and PI3K/AKT Pathways.
Zhang Q, Yang Z, Ou X, Zhang M, Ji R, Wu G
Phytotherapy research : PTR 2025 Nov;39(11):5174-5197
Phytotherapy research : PTR 2025 Nov;39(11):5174-5197
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
Wei K, He L, Li X, Wu M, Wang H, Hu L, Xu H, Zhang Y, Zhou L, Xu X, Guo L
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
The integrated treatment of photodynamic therapy and oncolytic Virotherapy: A dual-modal paradigm for breast Cancer.
Li Y, Wang K, Min Q, Lu H, Zhang G, Yan J
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113248
DNA damage agents trigger iNKT cell-mediated elimination of AML cells through activation of NF-κB/HLA-DRB6/CD1d pathway.
Tu G, Wu Q, Yuan Y, Jiang Q, Tang Y, Wu X, Lu Y, Lin J, Zhang Z, Wu L
Biochemical pharmacology 2025 Nov;241:117174
Biochemical pharmacology 2025 Nov;241:117174
Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA.
Wu LX, Xie JH, Li JY, Li WP, Mao XT, Huang LJ, Chen HT, Zhong JY, Lin LM, Su S, Li YY, Cao Q, Jin J
Cellular & molecular immunology 2025 Nov;22(11):1398-1413
Cellular & molecular immunology 2025 Nov;22(11):1398-1413
Sulfasalazine disrupts the interaction between TNFα and TNFR1 thus inhibiting NF-kB signaling activation to promote bone fracture healing.
Liu J, Qiu C, Wang X, Xiang Z, Sun J, Chang M, Ma Q, Zhuang Y, Zhao Y, Yang Q, Wang L, Liu X
Journal of pharmacological sciences 2025 Nov;159(3):139-150
Journal of pharmacological sciences 2025 Nov;159(3):139-150
Ferrum@albumin assembled nanoclusters inhibit NF-κB signaling pathway for NIR enhanced acute lung injury immunotherapy.
Guan X, Zou B, Jin W, Liu Y, Lan Y, Qian J, Luo J, Lei Y, Liang X, Zhang S, Xiao Y, Long Y, Qian C, Huang C, Tian W, Huang J, Lai Y, Gao M, Liao L
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5891-5907
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5891-5907
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
The total xanthones from Gentianella acuta alleviate acute myocardial infarction by targeting BRD4-mediated cardiomyocyte pyroptosis and inflammation.
Dai C, Sun J, Yang G, Zhang C, Zhang Y, Song Q, Liu X, Duan X, Yang H, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157156
Theaflavin-3,3'-digallate prevents alcoholic liver injury by suppressing hepatic TLR4/NF-κB signaling and modulating the gut-liver axis in mice.
Tang MG, Xiong LG, Huang JA, Hara Y, Zhang S, Liu ZH, Liu AL
The Journal of nutritional biochemistry 2025 Nov;145:110031
The Journal of nutritional biochemistry 2025 Nov;145:110031
Chronic ethanol exposure induces hippocampal neuroinflammation and neuronal damage via the astrocytic RUNX1/TOLLIP/TLR3 pathway.
Shen H, Zhang Q, Lv Q, Liu H, Wang C, Meng F, Guo Y, Pei J, Yu C, Tie J, Chen X, Zhang C, Yu H, Wang X
Brain, behavior, and immunity 2025 Nov;130:106081
Brain, behavior, and immunity 2025 Nov;130:106081
Harnessing NLRX1: a new frontier in mitigating inflammation in pulmonary hypertension.
Xiao Y, Cai Z, Bai M, Wu X, Wang W, Liu R, Luo Y
Respiratory research 2025 Nov 7;26(1):311
Respiratory research 2025 Nov 7;26(1):311
Exploration of new azole derivatives containing ethanolamine moiety as anti-UC agents by inhibiting NF-κB/MAPK pathways.
Ju MQ, Huang ZX, Mo QY, Liu S, Wang DX, Li YP, Wan CP, Mao ZW
Molecular diversity 2025 Nov 6;
Molecular diversity 2025 Nov 6;
SOGA1 drives ovarian cancer progression via regulation of GNAI1 and activation of the TNF/NF-κB pathway.
Long T, Li X, Zhou Y, Zhu C, Zhang M, Li M, Wei Z
Gene 2025 Nov 5;971:149800
Gene 2025 Nov 5;971:149800
SUN5 interacts with TRIM28, enhancing IκBα ubiquitination to promote glycolysis in colorectal cancer cells.
Chen J, Yang Y, Liu G, Huang L, Zhang Y, Wang Y, Xu X, Xing X
Acta biochimica et biophysica Sinica 2025 Nov 27;57(12):2094-109
Acta biochimica et biophysica Sinica 2025 Nov 27;57(12):2094-109
ADGRG6 Promotes Pancreatic Adenocarcinoma Progression Through the NF-κB/STAT6 Axis and Modulation of the Tumor Immune Microenvironment.
Li L, Yu Z, Lu X, Yang P, Zhang S, Lin Q, Han J
Current issues in molecular biology 2025 Nov 27;47(12)
Current issues in molecular biology 2025 Nov 27;47(12)
Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response.
Li M, Wei Z, Chen X, Wu H, Han X, Pei Y, Chen J, Ma S
Frontiers in bioscience (Landmark edition) 2025 Nov 26;30(11):45744
Frontiers in bioscience (Landmark edition) 2025 Nov 26;30(11):45744
Antitumor immunity of alcohol-soluble polysaccharide from Nostoc sphaeroides in non-small cell lung cancer.
Wu A, Jin Y, Chen Y, Pan K, Jiang Q, Tian L, Lai F, Liu N, Wang X, Pan J, Chen X, Xu J, Wang Z, Chen Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157487
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157487
Metabolomics and network pharmacology revealing the transdermal moxibustion compounds and their therapeutic mechanisms for rheumatoid arthritis.
Lai J, Lan T, Wang T, Wang D, Yu M, Su Y, Song G, Tseng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157479
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157479
Huang-Lian-Jie-Du decoction alleviates diabetic ischemic stroke by modulating gut microbiota-derived short-chain fatty acids.
Chen C, Luo WH, Li A, Wu HZ, Chen DY, Chen JX, Wang ZQ, Wang SM, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157476
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157476
Qihuang Yishen formula attenuates renal tubular injury by modulating inflammation via the cGAS/STING pathway in diabetic kidney disease.
Guo Y, Xue T, Meng X, Yan P, Zhang M, Zhang Q, Li T, Shi K, Zhang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157399
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157399
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Gong S, Xu Y, Zhao R, Yu J, Bao L, Zhang Y, Li F, Jiao L, Kou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone.
Zheng R, He Y, Wang Y, Chen Y, Yang L, Wang R, Wu S, Xie H, Xie S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157327
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157327
Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke rat.
Zheng T, Jiang T, Chen Y, Xie J, Yu W, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157267
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157267
Targeting ICAM1 through LIF-mediated NF-κB/JAK2-STAT3 crosstalk protects nucleus pulposus from IL-1β-driven pyroptosis to ameliorate intervertebral disc degeneration.
Wang Z, Liu J, Xu H, Sun Y, Xu S, He X
Journal of orthopaedic surgery and research 2025 Nov 22;20(1):1096
Journal of orthopaedic surgery and research 2025 Nov 22;20(1):1096
Downregulation of oar-miR-125b Drives Blood-Brain Barrier Breakdown Through the TNFSF4-NF-κB Inflammatory Axis in Enterococcus Faecalis Meningitis.
Jiao L, Wu Y, Qi B, Zhao P, Zhou M, Zhang R, Li Y, Ren J, Cao S, Qi Y
Microorganisms 2025 Nov 21;13(12)
Microorganisms 2025 Nov 21;13(12)
CLOCK-mediated acetylation of NF-κB p65 drives immune evasion in breast cancer.
Quan X, Li N, Huang J, Duan Y
Biology direct 2025 Nov 20;20(1):112
Biology direct 2025 Nov 20;20(1):112
Identification of IL1R1 as a potential key PANoptosis-related gene in myocardial ischemia-reperfusion injury using machine learning.
Peng S, Li K, Hu B, Liu P, Yang Y
Scientific reports 2025 Nov 20;15(1):40987
Scientific reports 2025 Nov 20;15(1):40987
Cordycepin Mitigates Sepsis-Associated Encephalopathy by Promoting Microglial M2 Polarization via the IL-17a/IL-17RA/NF-κB Axis.
Yuan Y, Fu G, Zhu Y, Xu J, Li F, Sheng Z
Molecular neurobiology 2025 Nov 19;63(1):72
Molecular neurobiology 2025 Nov 19;63(1):72
Integrative Transcriptomic and Metabolomic Analysis Reveals That Acanthopanax senticosus Fruit Ameliorates Cisplatin-Induced Acute Kidney Injury by Suppressing the NF-κB/PI3K-AKT Pathway via UGT1A1 Regulation.
Han L, Tang Z, Ma X, Zhang Q, Han Y, Wang Q, Liu J, Bian X, Gao L, Xu M, Sun X
International journal of molecular sciences 2025 Nov 18;26(22)
International journal of molecular sciences 2025 Nov 18;26(22)
Orosomucoid 1 Participates in Alveolar Hypercoagulation and Fibrinolytic Inhibition Involving NF-κB Signaling Pathway in LPS-Induced ARDS.
Chen X, Liu Y, Mu S, Chen T, Yuan J, Xiao C, Dong Q, Li Q, Wang Y, Chen Q, Li S, Li W, Shen F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71147
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71147
TIM3 attenuates morphine antinociceptive tolerance and microglial neuroinflammation by suppressing the TRAF6/NF-κB pathway in male mice.
Yang H, Shen T, Qi Z, Yang Z, Zhang M, Jiang J, Sun Z, Lu C
Neuropharmacology 2025 Nov 15;279:110638
Neuropharmacology 2025 Nov 15;279:110638
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis.
Yuan H, Zhou N, Li J, Li X, Zhou K, Qi J
International immunopharmacology 2025 Nov 14;165:115439
International immunopharmacology 2025 Nov 14;165:115439
Tetrandrine enhances cognition in SAH rats via gut microbiota CYP51 and TLR4 signaling.
Liu H, Zou Q, Xiang T, Zhu R, Chen Z, Chen R
Scientific reports 2025 Nov 11;15(1):39418
Scientific reports 2025 Nov 11;15(1):39418
Exercise increases bone mass by lactate/Gpr81 signaling pathway.
Guo Y, He L, Xue A, Sun Y, Liu R, Zhang M, Liu Y, Yu F, Guo P, Zhao Y, Tang L, Li X, Lu W, Li Y, Sun P
Communications biology 2025 Nov 10;8(1):1548
Communications biology 2025 Nov 10;8(1):1548
Folate Attenuates Ulcerative Colitis via PI3K/AKT/NF-κB/MLCK Axis Inhibition to Restore Intestinal Barrier Integrity.
Zhang S, Cheng T, Chen Y, Wang M, Wang G, Aa J
Biology 2025 Nov 10;14(11)
Biology 2025 Nov 10;14(11)
Application of Dental Pulp Stem Cell-Derived Intracellular Vesicles for Diabetic Wound Healing.
Pang P, Liu Y, Song H, Ye Z, Zhou H, Zhang R, Kumeria T, She W, Xu C, Mei PL, He Y, Ye Q
Diabetes 2025 Nov 1;74(11):2060-2074
Diabetes 2025 Nov 1;74(11):2060-2074
Underlying metabolic syndrome exacerbates Vibrio vulnificus-induced acute kidney injury via systemic Th17/Treg dysregulation.
More MP, Saha P, Roy S, Trivedi A, Chatterjee S
American journal of physiology. Renal physiology 2025 Nov 1;329(5):F627-F644
American journal of physiology. Renal physiology 2025 Nov 1;329(5):F627-F644
Remote ischemic conditioning as a potential therapy for Parkinson's Disease: Inhibiting TLR4-Driven neuroinflammation and oxidative damage.
Cai L, Ding Y, Tekreeti AA, Li F, Zhu Y, Geng X, Ji X
Brain research 2025 Nov 1;1866:149920
Brain research 2025 Nov 1;1866:149920
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Zheng X, Wang J, Zhou H, Chai Y, Li Z, Chen M, Yang Z, Xu C, Lei C, He Y, Zou D, Ye Q
Bioactive materials 2025 May;47:313-326
Bioactive materials 2025 May;47:313-326
Early Potentially Irreversible Cardiac Damage in Fabry Disease Precedes Gb3 Inclusion Body Formation.
Lee CL, Chen PS, Lu YY, Chiang YT, Yen CT, Huang CY, Cheng YF, Lin HY, Chen YR, Niu DM
The Canadian journal of cardiology 2025 May;41(5):939-951
The Canadian journal of cardiology 2025 May;41(5):939-951
Gastrodin Ameliorates Tau Pathology and BBB Dysfunction in 3xTg-AD Transgenic Mice by Regulating the ADRA1/NF-κB/NLRP3 Pathway to Reduce Neuroinflammation.
Li B, Wang L, Xiao Y, Wang Y, Wang Y, Peng Y, Zhang A, Tang Z, Qi X
Phytotherapy research : PTR 2025 May;39(5):1996-2016
Phytotherapy research : PTR 2025 May;39(5):1996-2016
Eicosapentaenoic acid (EPA) reduced lipopolysaccharide-stimulated inflammatory response of RAW264.7 cells via the miR-125b-5p/CREB axis.
Zhang L, Lin L, Xiao B, Huang K, Liu J, Chen YL, Lu L, Zhang Z, Zhang L, Li J, Ho KT, Luo L, Huang SY, Li G
International journal of biological macromolecules 2025 May;310(Pt 4):143511
International journal of biological macromolecules 2025 May;310(Pt 4):143511
Hyaluronic acid-modified PtPdCo-CQ nanocatalyst with triple enzyme-like activities regulates macrophage polarization and autophagy levels for the treatment of rheumatoid arthritis.
Zhang L, Wu G, Yao J, Wang D, Gao F, Qian Z
International journal of biological macromolecules 2025 May;309(Pt 4):143143
International journal of biological macromolecules 2025 May;309(Pt 4):143143
Phosphorylation-driven regulation of SIRT1 in muscle senescence: Insights from molecular dynamics simulation and experimental validation.
Liu S, Shan L, Li Y, Xiang J, Zhang H
International journal of biological macromolecules 2025 May;306(Pt 4):141734
International journal of biological macromolecules 2025 May;306(Pt 4):141734
Reno protective potential of taxifolin liposomes modified by chitosan in diabetic mice.
Zhao Y, Ding Q, He Q, Zu T, Rong Z, Wu Y, Shmanai VV, Jiao J, Zheng R
International journal of biological macromolecules 2025 May;306(Pt 2):141464
International journal of biological macromolecules 2025 May;306(Pt 2):141464
The Combination of MIF Inhibitor and AEP Targeted Inhibitor to Reduce Lung Metastasis in Breast Cancer and Its Mechanism.
Chen J, Xu W, Meng L, Zhang X, Lin M, Zhang S, Liu Y, Guo F
Journal of cellular and molecular medicine 2025 May;29(10):e70616
Journal of cellular and molecular medicine 2025 May;29(10):e70616
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Cao MM, Guo Z, Wang J, Ma HY, Qin XY, Hu Y, Lan R
Free radical biology & medicine 2025 May;232:340-352
Free radical biology & medicine 2025 May;232:340-352
Neuroprotective effects of hirudin against cerebral ischemia-reperfusion injury via inhibition of CCL2-mediated ferroptosis and inflammatory pathways.
Liao J, Chen H, Liao Y, Luo C, Wang Z, Zhang F, Fu C
Brain research bulletin 2025 May;224:111293
Brain research bulletin 2025 May;224:111293
ZACN Associated with Poor Prognosis Promotes Proliferation of Kidney Renal Clear Cell Carcinoma Cells by Inhibiting JTC801-Induced Alkaliptosis.
Li Y, Li C
Applied biochemistry and biotechnology 2025 May;197(5):3346-3362
Applied biochemistry and biotechnology 2025 May;197(5):3346-3362
Targeting HPK1 inhibits neutrophil responses to mitigate post-stroke lung and cerebral injuries.
Zhang T, Sun Y, Xia J, Fan H, Shi D, Wu Q, Huang M, Hou XY
EMBO molecular medicine 2025 May;17(5):1018-1040
EMBO molecular medicine 2025 May;17(5):1018-1040
Herbal-based Xuebijing injection ameliorated vascular endothelial dysfunction via inhibiting ACLY/MYB/RIG-I axis in sepsis-associated lung injury.
Cui J, Deng Y, Li X, Gao L, Li J, Li Z, Qu H, Chu Y, Gu Y, Meng M, Li R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156573
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156573
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease.
Sun F, Ma Y, Li D, Yang Q, Yuan T, Liu T, Tian X, Zhu Z, Zheng W, Wang Y, Wang W
Basic & clinical pharmacology & toxicology 2025 May;136(5):e70036
Basic & clinical pharmacology & toxicology 2025 May;136(5):e70036
β-Hydroxybutyrate aggravates LPS-induced inflammatory response in bovine endometrial epithelial cells by activating the oxidative stress/NF-κB signaling pathway.
Yang W, Wang F, Liu J, Wang X, Zhang H, Gao D, Wang A, Jin Y, Chen H
International immunopharmacology 2025 May 8;154:114609
International immunopharmacology 2025 May 8;154:114609
Targeting inflammation and necroptosis in diabetic kidney disease: A novel approach via PPARα modulation.
Wang Y, Feng X, Li Y, Niu S, Li J, Shi H, Wang G, Wang L
International immunopharmacology 2025 May 8;154:114562
International immunopharmacology 2025 May 8;154:114562
Bicuculline ameliorates metabolic dysfunction-associated steatotic liver disease by inhibiting the nuclear factor-kappa B pathway and reducing lipid accumulation.
Wang XM, Dai Z, Lu DJ, Bao CQ, Yang NB, Zhou YP
World journal of gastroenterology 2025 May 7;31(17):105438
World journal of gastroenterology 2025 May 7;31(17):105438
Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury.
Liu Z, Zhao Z, Xiao Z, Li M, Wang X, Huang Y, Li Y
Cell death discovery 2025 May 7;11(1):223
Cell death discovery 2025 May 7;11(1):223
Tetrandrine Improves Ventricular Remodeling and Inflammation via Inhibition of the MAPK/NF-κB Pathway.
Wang Y, Zhang R, Li J, Guo S, Yuan Y, Zheng R, Xu Y, Cai X
International heart journal 2025 May 31;66(3):463-474
International heart journal 2025 May 31;66(3):463-474
RBAP48 facilitates the oral squamous cell carcinoma process in an androgen receptor-dependent and independent manners.
Wang X, Yan G, Li H, Wang C, Kang Y, Wang S, Liu W, Lin L, Zou R, Zeng K, Wang M, Luan R, Zhou B, Bai Y, Yang D, Ning B, Sun G, Zhao Y
Communications biology 2025 May 30;8(1):829
Communications biology 2025 May 30;8(1):829
Aryl Hydrocarbon Receptor-Dependent miRNA-382-5p Mediates the Classical Pyroptosis Induced by Foodborne Benzo(a)pyrene through Targeting IκB in Liver.
Meng Y, Jia Y, He Z, Li J, Yuan L
Journal of agricultural and food chemistry 2025 May 28;73(21):12978-12992
Journal of agricultural and food chemistry 2025 May 28;73(21):12978-12992
Huatanhuoxue decoction alleviates airway inflammation by regulating IL-17A signaling pathway in obese asthmatic mice.
Sun Y, Jia Y, Yan X, Zhang Q, Li X, Yang Z, Wei D, Wu X, Mao Z, Cao X, Tong X, Huang F
Journal of ethnopharmacology 2025 May 28;348:119814
Journal of ethnopharmacology 2025 May 28;348:119814
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia.
Wang YN, Liu S
BMC oral health 2025 May 28;25(1):823
BMC oral health 2025 May 28;25(1):823
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
Wang W, Liu M, Wu H, Li J, Lv W, Li C, Du C, Feng C, Zhang Y, Cai Y, Jia Y, Hu Y, Qu J, Zhang S, Wu F
Scientific reports 2025 May 26;15(1):18374
Scientific reports 2025 May 26;15(1):18374
Protective Effect of Obeticholic Acid on Sepsis-Induced Liver Dysfunction via Regulating Bile Acid Homeostasis.
Wang J, Ma L, An Y, Ge Y, Xu D, Mao E
Pharmaceuticals (Basel, Switzerland) 2025 May 21;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 May 21;18(5)
THG-1/TSC22D4 Promotes IL-1 Signaling through Stabilization of TRAF6 in Squamous Cell Carcinoma.
Okano Y, Suzuki H, Watanabe Y, Abdelaziz M, Manevich L, Kawanishi K, Ozaki H, Ishii R, Matsumoto S, Goto N, Zheng L, Okita Y, Hwang J, Nakayama M, Shima Y, Sakamoto N, Noguchi M, Tabuchi K, Kato M
Molecular cancer research : MCR 2025 May 2;23(5):463-476
Molecular cancer research : MCR 2025 May 2;23(5):463-476
Microcystin-LR induces lung injury in mice through the NF-κB/NLRP3 pathway.
Zhang Y, Guan Y, Dai M, Yang Y, Yang F
Journal of toxicology and environmental health. Part A 2025 May 19;88(10):385-394
Journal of toxicology and environmental health. Part A 2025 May 19;88(10):385-394
Gut microbiota contributes to obstructive sleep apnea-induced hypertension by gut-heart axis in mice.
Zhang X, Yin Y, Chen Y, Lin L, Shen S, Fang F, Wang Q
International immunopharmacology 2025 May 16;155:114667
International immunopharmacology 2025 May 16;155:114667
Effects of Adipose-Derived Mesenchymal Stem Cell-Secretome on Pyroptosis of Laparoscopic Hepatic Ischemia Reperfusion Injury in a Porcine Model.
Ma Y, Cao L, Li P, Jiao Z, Liu X, Lu X, Liu T, Wang H
Cells 2025 May 15;14(10)
Cells 2025 May 15;14(10)
Multi-Omics Unveils Inflammatory Regulation of Fermented Sini Decoction Dregs in Broilers Infected with Avian Pathogenic Escherichia coli.
Mo S, Fang X, Xiao W, Huang B, Li C, Yang H, Wu Y, Wang Y, Ma H
Veterinary sciences 2025 May 15;12(5)
Veterinary sciences 2025 May 15;12(5)
HDLR-SR-BI Expression and Cholesterol Uptake are Regulated via Indoleamine-2,3-dioxygenase 1 in Macrophages under Inflammation.
Chini A, Guha P, Rishi A, Bhat N, Covarrubias A, Martinez V, Devejian L, Nguyen BN, Mandal SS
Langmuir : the ACS journal of surfaces and colloids 2025 May 13;41(18):11253-11271
Langmuir : the ACS journal of surfaces and colloids 2025 May 13;41(18):11253-11271
Comprehensive wound healing using ETN@Fe(7)S(8) complex by positively regulating multiple programmed phases.
Chen M, Liu T, Wang X, Gao L, Cheng Y, Jiang J, Zhang J
Journal of nanobiotechnology 2025 May 13;23(1):342
Journal of nanobiotechnology 2025 May 13;23(1):342
Inhalable neutrophil-mimicking nanoparticles for chronic obstructive pulmonary disease treatment.
Yu Q, Zhang Q, Zhu J, Pan F, Zhang H, Chen L, Shen J, Liu Y, Ji Z, Zhu Y, Chen Q, Yang Y
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113648
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113648
Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.
Xue T, Song Y, Zhao J, Fan G, Liu Z
The journal of headache and pain 2025 May 1;26(1):97
The journal of headache and pain 2025 May 1;26(1):97
ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation.
Huang LQ, Yan TX, Wang BS, Li H, Zhou NB
Neoplasia (New York, N.Y.) 2025 Mar;61:101123
Neoplasia (New York, N.Y.) 2025 Mar;61:101123
CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment.
Xu J, Li N, Xie H, Duan C, Liao X, Li R, Zhang H, Pan Y, Ma X, Du S, Sheng J, Wang X, Yang L, Jin P
Translational oncology 2025 Mar;53:102310
Translational oncology 2025 Mar;53:102310
Resveratrol Alleviates Liver Fibrosis by Targeting Cross-Talk Between TLR2/MyD88/ERK and NF-κB/NLRP3 Inflammasome Pathways in Macrophages.
Lei JQ, Xie QL, Li QP, Qin SY, Wu JH, Jiang HX, Yu B, Luo W
Journal of biochemical and molecular toxicology 2025 Mar;39(3):e70208
Journal of biochemical and molecular toxicology 2025 Mar;39(3):e70208
Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner.
Qiao CM, Ma XY, Tan LL, Xia YM, Li T, Wu J, Cui C, Zhao WJ, Shen YQ
Experimental neurology 2025 Mar;385:115142
Experimental neurology 2025 Mar;385:115142
Suppression of Sepsis Cytokine Storm by Escherichia Coli Cell Wall-Derived Carbon Dots.
Li Y, Huang X, Qiao Q, Li Y, Han X, Chen C, Chen Y, Guo S, Zhang Y, Gao W, Liu H, Sun T
Advanced materials (Deerfield Beach, Fla.) 2025 Mar;37(12):e2414237
Advanced materials (Deerfield Beach, Fla.) 2025 Mar;37(12):e2414237
Structural characterization of an apple polysaccharide and its anti-inflammatory effect through suppressing TLR4/NF-κB signaling.
Ma S, Zhang R, Li L, Wang J, Zheng M, Guo X, Miao S, Quan W, Liu W, Shi X
International journal of biological macromolecules 2025 Mar;296:139760
International journal of biological macromolecules 2025 Mar;296:139760
Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity.
Li S, Yin Y, Dong X, Xu L, Yang Z, Li H, Zou Y, Wu Z
Biological trace element research 2025 Mar;203(3):1539-1554
Biological trace element research 2025 Mar;203(3):1539-1554
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Li R, Ding X, Lei M, Li P, Giannenas I, Wang J, Zhu W
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Vagus nerve stimulation inhibits PANoptosis and promotes neurofunctional recovery of cerebral ischemic stroke in a Sirt1-dependent manner.
Tang H, Wen J, Wang L, Yang Q, Qin T, Ren Y, Zhao Y, Li C, Li J, Cao H, Xu J, Yang Q
Neurochemistry international 2025 Mar;184:105950
Neurochemistry international 2025 Mar;184:105950
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
Wang C, Li X, Ye T, Gu J, Zheng Z, Chen G, Dong J, Zhou W, Shi J, Zhang L
Bioorganic chemistry 2025 Mar;156:108170
Bioorganic chemistry 2025 Mar;156:108170
Evaluation of cytoprotective effects of cannabidiol on neuroinflammation and neurogenesis process in rat offsprings.
Catakli D, Erzurumlu Y, Asci H, Savran M, Sezer S
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108761
Reproductive toxicology (Elmsford, N.Y.) 2025 Mar;132:108761
Ferroptosis-Related Genes Are Effective Markers for Diagnostic Targets of Crohn's Disease.
Liu P, Liu Q, Tian Y, Cai P, Bai J
Immunity, inflammation and disease 2025 Mar;13(3):e70170
Immunity, inflammation and disease 2025 Mar;13(3):e70170
Photothermal Coating on Zinc Alloy for Controlled Biodegradation and Improved Osseointegration.
Hsu Y, He Y, Zhao X, Wang F, Yang F, Zheng Y, Zhou Y, Xia D, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(9):e2409051
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(9):e2409051
FABP4 Mediates Inflammation to Regulate Endometrial Epithelial Cell Function During Early Gestation in Sheep.
Chen Y, Liu C, Liu Z, Yu H, Peng X, Wang J, Hu G
Veterinary medicine and science 2025 Mar;11(2):e70193
Veterinary medicine and science 2025 Mar;11(2):e70193
Network pharmacology and in vivo study: Unraveling the therapeutic mechanisms of Panax ginseng in potentially treating ulcerative colitis.
Qin Y, Zhang RY, Zhang Y, Zhao YQ, Hao HF, Wang JP
World journal of gastroenterology 2025 Mar 7;31(9):100271
World journal of gastroenterology 2025 Mar 7;31(9):100271
Alleviation of inflammation in paraventricular nucleus and sympathetic outflow by melatonin efficiently repairs endplate porosities and attenuates spinal hyperalgesia.
Yan M, Lv X, Zhang S, Song Z, Hu B, Qing X, Kou H, Chen S, Shao Z, Liu H
International immunopharmacology 2025 Mar 6;149:114213
International immunopharmacology 2025 Mar 6;149:114213
Erianin alleviates autoimmune myocarditis by suppressing the M1 polarization of macrophages via the NF-κB/NLRP3 signaling pathway.
Liu W, Mao Y, Li H, Hu J, Gan T, Wang Y, Wang Y, Wang Z
European journal of pharmacology 2025 Mar 5;990:177292
European journal of pharmacology 2025 Mar 5;990:177292
Chrysin ameliorates dextran sulfate-induced ulcerative colitis in mice by modulating inflammation and gut microbiota.
Yao X, Chen Y, Li Y, Mo J, Liu X, Wang P, Jia D, Li H, Guo C
International journal of colorectal disease 2025 Mar 4;40(1):57
International journal of colorectal disease 2025 Mar 4;40(1):57
Isorhamnetin ameliorates hyperuricemia by regulating uric acid metabolism and alleviates renal inflammation through the PI3K/AKT/NF-κB signaling pathway.
Kong X, Zhao L, Huang H, Kang Q, Lu J, Zhu J
Food & function 2025 Mar 31;16(7):2840-2856
Food & function 2025 Mar 31;16(7):2840-2856
Probiotic nanovesicles encapsulating baicalin: a strategy to overcome colorectal cancer.
Li Y, Zhao X, Wang D, Wang R, Zhu R, You X, Liu X, Li Y
Letters in applied microbiology 2025 Mar 3;78(3)
Letters in applied microbiology 2025 Mar 3;78(3)
Unveiling the anti-inflammatory mechanism of exogenous hydrogen sulfide in Kawasaki disease based on network pharmacology and experimental validation.
Yu L, Luo Q, Rao X, Xiao X, Wang P
Scientific reports 2025 Mar 3;15(1):7410
Scientific reports 2025 Mar 3;15(1):7410
Fatty acid synthase inhibitor cerulenin attenuates glioblastoma progression by reducing EMT and stemness phenotypes, inducing oxidative and ER stress response, and targeting PI3K/AKT/NF-κB axis.
Pekmez M, Mete ŞB, Aksüt Y, Öğütcü İ, Baştürk FN, Gerçek YC, Şengelen A
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
Medical oncology (Northwood, London, England) 2025 Mar 25;42(5):136
Effect of Benzyl Isothiocyanate on Anaplastic Thyroid Cancer Evaluated by Network Pharmacology Combined with Experiments.
Ma C, Zhang Q, Wang Y, Li D, Zhang H, Jia Q, Zheng W, Tan J, Xu K, Yang L, Meng Z
ACS omega 2025 Mar 25;10(11):11063-11076
ACS omega 2025 Mar 25;10(11):11063-11076
Medium- and long-chain triacylglycerols as enteral nutrition enhancing the nutritional status of postoperative rats undergoing chemotherapy by increasing the bioavailability of functional fatty acids.
Wang Y, Wei W, Wang Y, Liu X, Jin Q, Wang X
Food chemistry 2025 Mar 15;468:142410
Food chemistry 2025 Mar 15;468:142410
Glycidol induces necroptosis and inflammation through autophagy-necrosome pathway in renal cell and mice.
Lu J, Wei H, Yao X, Chen Y, Liu M, Guan S
The Science of the total environment 2025 Mar 10;968:178852
The Science of the total environment 2025 Mar 10;968:178852
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z
Acta biomaterialia 2025 Mar 1;194:396-410
Acta biomaterialia 2025 Mar 1;194:396-410
GIT2 negatively regulates the NF-κB pathway directly or indirectly by regulating TRAF3 expression to promote osteogenic differentiation of BMSCs.
Wang Y, Wang C, Gong Y, Li Q, Liu M, Sun H
Tissue & cell 2025 Jun;94:102790
Tissue & cell 2025 Jun;94:102790
The safety assessment of cinnabar: Effects of co-administration with selenium on renal toxicity in mice.
Han Z, Zhuo Y, Dai Z, Zhang X, Zhu B, Liu Y, Chai Z, Wu J, Chen L
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127671
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127671
Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.
Hu H, Xie T
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
Cell biochemistry and biophysics 2025 Jun;83(2):2009-2021
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
Bai X, Duan Z, Deng J, Zhang Z, Fu R, Zhu C, Fan D
Journal of advanced research 2025 Jun;72:37-52
Journal of advanced research 2025 Jun;72:37-52
Astaxanthin Alleviates Lung Injury by Regulating Oxidative Stress, Inflammatory Response, P2X7 Receptor, NF-κB, Bcl-2, and Caspase-3 in LPS-Induced Endotoxemia.
Ozkanlar S, Ozkanlar Y, Kara A, Dalkilinc E
Environmental toxicology 2025 Jun;40(6):924-934
Environmental toxicology 2025 Jun;40(6):924-934
β-Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti-Inflammatory Pathway.
Zhang Y, Jin X, Xia H, Wu X, Chen W, Zhuang M, Tang S
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70287
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70287
Multi-stage cooperative ROS-responsive hydrogel platform for drug delivery in myocardial ischemia-reperfusion injury repair.
Luo Q, Cheng N, Yang Y, Shao N, Nie T, Chen J, Huang C, Zhang S, Huang Y, Ieong CM, Zhang X, Hu K, Xiao Z, Luo L
Materials today. Bio 2025 Jun;32:101854
Materials today. Bio 2025 Jun;32:101854
Black phosphorus nanosheets activate tumor immunity of glioblastoma by modulating the expression of the immunosuppressive molecule PD-L1.
Xiong Y, He C, Qi J, Xiong M, Liu S, Zhao J, Li Y, Liu G, Deng W
Biomaterials 2025 Jun;317:123062
Biomaterials 2025 Jun;317:123062
Alhagi camelorum seed polysaccharide alleviates methylglyoxal-induced skin damage via antioxidant and anti-inflammatory actions.
Chen Q, Li M, Li Z, Mei M, Lin Y, Shu P, Zhu W
International journal of biological macromolecules 2025 Jun;311(Pt 3):143661
International journal of biological macromolecules 2025 Jun;311(Pt 3):143661
Ultrasound-responsive taurine lipid nanoparticles attenuate oxidative stress and promote macrophage polarization for diabetic wound healing.
Luo Z, Zheng S, Hu Z, Li P, Zeng J, Lu Y, Ali M, Chen Z, Wang Q, Qi F
Free radical biology & medicine 2025 Jun;233:302-316
Free radical biology & medicine 2025 Jun;233:302-316
Ginsenoside Rk1 Ameliorates Non-Alcoholic Fatty Liver Disease by Targeting CD36 to Modulate the AMPK Signaling Pathway.
Wu Y, Duan Z, Qu L, Liu Y, Ma X, Fan D
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
Food research international (Ottawa, Ont.) 2025 Jun;211:116426
SFTSV NSs degrades SAFA via autophagy to suppress SAFA-dependent antiviral response.
Yu TM, Li ZM, Zhang WK, Li B, Liu Q, Zhou CM, Yu XJ
PLoS pathogens 2025 Jun;21(6):e1013201
PLoS pathogens 2025 Jun;21(6):e1013201
Prostaglandin E2 alleviates inflammatory response and lung injury through EP4/cAMP/IKK/NF-κB pathway.
Tang Y, Pan W, Ding W, Pan X, Zhu J, Chen H, Zhu X, Chen J, Cheng Z, Zhang Y, Zhang B
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167801
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167801
Gen-17, a beta-methyl derivative of Genipin, attenuates LPS-induced ALI by regulating Keap1-Nrf2/HO-1 and suppressing NF-κB and MAPK-dependent signaling pathways.
Zhu YS, Shah SAA, Yang BY, Fan SS, He L, Sun YR, Shang WB, Qian Y, Zhang X
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167770
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167770
Targeted lipidomic reveals dietary LA/n-3 PUFAs regulate inflammation and redox status via oxylipins in bivalves.
Zhu Y, Liao K, Liu Y, Huang H, Zhang Y, Ge H, Chen D, Ma B, Xu J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159631
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159631
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Zhao T, Liu W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Jun;1870(5):159613
Extraction technology, component analysis, and the immunomodulatory effects in immunosuppressed broilers of total flavonoids extract from the thorns of Gleditsia sinensis Lam.
Xu J, Zhou A, Yue S, Zhao H, Xiao Y, Guo Y, Mo F, Liu M, Tian C
Fitoterapia 2025 Jun;183:106524
Fitoterapia 2025 Jun;183:106524
Acupuncture protects against ischemic stroke by inhibiting the NF-κB pathway.
Wang L, Chen L, Wu J, Liu C, Chi C, Wang S
IBRO neuroscience reports 2025 Jun;18:370-377
IBRO neuroscience reports 2025 Jun;18:370-377
Curcumol Ameliorates Cisplatin-induced Nephrotoxicity by Targeting TAK1 and Inhibiting MAPK and NF-κB Pathways.
Jin X, Yuan M, Wang L, Zha H, Zheng Z, Xu Z, Shi J, Liang G, Zhou Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156752
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156752
Construction of a toxicity pathway from activation of the TLR4/NF-κB/NLRP3 axis to Parkinson's disease-like non-motor symptoms in mice.
Wang K, Shi G, Li Y, Liu Q, Zhang Q, Wu C, Jiao Y, Ma Y, Qi A, Huang M
Environmental toxicology and pharmacology 2025 Jun;116:104706
Environmental toxicology and pharmacology 2025 Jun;116:104706
Luteolin ameliorates kainic acid-induced seizure by modulating GADD45B and reducing oxidative stress in hippocampal neurons.
Luo C, Wang Z, Liao J, Fu C, Zhang F, Zhao J
Neuropeptides 2025 Jun;111:102524
Neuropeptides 2025 Jun;111:102524
18β-glycyrrhetinic acid improves pulmonary hypertension by regulating the vascular non-inflammatory molecule-1/L-arginine/nitric oxide signaling pathway.
Shanahati D, Yang T, Fang L, Nijiati Y, Aihemaitituoheti A, Abudukeremu A, Aikemu A
European journal of pharmacology 2025 Jun 5;996:177382
European journal of pharmacology 2025 Jun 5;996:177382
Discovery of novel rigid STING PROTAC degraders as potential therapeutics for acute kidney injury.
Ma R, Fu R, Wang Y, Njobvu KM, Fan Y, Yang Z, Chen M, Liu F, Jiang Z, Rao Y, Huang L, Xu C, Chen J, Liu J
European journal of medicinal chemistry 2025 Jun 5;290:117539
European journal of medicinal chemistry 2025 Jun 5;290:117539
Unveiling the mechanisms of mechanical loading-induced knee osteoarthritis through transcriptomics.
Wu Y, Li A, Sun N, Jiang Z, Li Y, Zhou Z, Li X, Zhao D, Leng X, Dong H
International immunopharmacology 2025 Jun 5;157:114785
International immunopharmacology 2025 Jun 5;157:114785
Cerium-Organic Framework and Resveratrol Composite Hydrogel Scaffold with Dual Antioxidant Activity for Enhanced Bone Regeneration.
Lu Y, Zhang L, Yang B, Hu H, Sun H, Guo D
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
ACS applied materials & interfaces 2025 Jun 4;17(22):31828-31842
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Chen C, Qi M, Xu Z, Wen J, Tang W, Diao H, Li Z, Chu Y, Feng F, Tang Z
Food & function 2025 Jun 3;16(11):4415-4436
Food & function 2025 Jun 3;16(11):4415-4436
Euphorbia humifusa Willd. extract alleviates imiquimod-induced psoriasis-like skin lesions in mice by modulating the IL-17 signaling pathway.
Alimujiang A, Wang H, Chen L, Kang Y, Zhao J, Wei W, Huo S, Xu D, Li Z
Journal of ethnopharmacology 2025 Jun 26;350:120030
Journal of ethnopharmacology 2025 Jun 26;350:120030
Overexpression of S100B promotes depressive-like behaviors in stroke-induced rats by modulating the PI3K/AKT/NF-κB pathway.
Lei H, Zhang F, Tao M, Lang J, Pei Y, Liu H, Zhang Z, Song J
Behavioural brain research 2025 Jun 25;488:115597
Behavioural brain research 2025 Jun 25;488:115597
Xanthoxylin Regulating the Inflammatory Microenvironment After Spinal Cord Injury Through Inhibition of the NF-κB Signaling Pathway.
Fan Z, Ye L, Wang S, Zhu Z, Wu C, Wu C, Kong L, Ning R
Neuromolecular medicine 2025 Jun 19;27(1):47
Neuromolecular medicine 2025 Jun 19;27(1):47
Mechanisms of Aletris spicata (Thunb.) Franch. Extract in Asthma Therapy: Oxidative Stress, Inflammation, and Gut Microbiota.
Yang J, Chen Z, Zhu Y, Chen T, Zhou Y, Wang Z
Biology 2025 Jun 19;14(6)
Biology 2025 Jun 19;14(6)
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway.
Lu D, Liu L, Que W, Fan R, Ke P, Dong J, Gan Y, Xiao F
Journal of neuroinflammation 2025 Jun 16;22(1):158
Journal of neuroinflammation 2025 Jun 16;22(1):158
Long-Term Treatment with Low-Level Arsenite Induces Aberrant Proliferation and Migration via Redox Rebalance in Human Urothelial Cells.
Yan X, Zhou Q, Xi S, Jin P
Cells 2025 Jun 16;14(12)
Cells 2025 Jun 16;14(12)
Qingfei Litan decoction alleviated Klebsiella pneumoniae-induced pneumonia by targeting the TLR4/MyD88/NF-κB axis via miR-146a-5p.
Wei R, Zeng Z, Chen S, Shi Y, Ding Q
Journal of ethnopharmacology 2025 Jun 12;349:119947
Journal of ethnopharmacology 2025 Jun 12;349:119947
Guyuan Jiannao decoction improves neurovascular unit dysfunction by regulating PI3K/AKT/NF-κB signaling pathway in cerebral small vessel disease rats.
Zhong Z, Long H, Li N, Liu T, Wu M, Wang J, Liu M, Zhang X, Mei Z, Fang R, Ge J, Meng P
Journal of ethnopharmacology 2025 Jun 12;349:119942
Journal of ethnopharmacology 2025 Jun 12;349:119942
Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.
Cheng Z, Gao H, Shi P, Zhang A, Chen X, Chen Y, Gan W, Zhao K, Li S, Yang C, Zhang Y
Bone research 2025 Jun 12;13(1):62
Bone research 2025 Jun 12;13(1):62
Sea Cucumber Fucoidan Inhibits Helicobacter pylori Gastritis via MAPK/NF-κB Signaling and Gut Microbiota Modulation.
Cao J, Yao M, Wang K, Qin L, Zhang Q, Zhang H, Wei J, Qu C, Xue C, Miao J
Journal of agricultural and food chemistry 2025 Jun 11;73(23):14333-14352
Journal of agricultural and food chemistry 2025 Jun 11;73(23):14333-14352
Potential of Ginger Oil to Prevent 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Lung Cancer Through Gut Microbiota Modulation and Inflammatory Response Inhibition.
Ding Y, Zhang L, Zhao W, Wang T, Shi Y, Zhuang C, Qu Z
Molecular nutrition & food research 2025 Jul;69(13):e70103
Molecular nutrition & food research 2025 Jul;69(13):e70103
LMO2 confers value as a potential immunotherapy marker in pan-cancer analysis and inhibits progression of Clear Cell Renal Cell Carcinoma.
Wang H, Wang C, Wei J, Zhao X, Yang X, Li R, Li M, Zhu Z
Translational oncology 2025 Jul;57:102409
Translational oncology 2025 Jul;57:102409
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
Li F, Qi Q, Qiao Y, Huang Y, Lu Y, Gu K, Liu H, Gao C, Liu S, Wu H
International journal of molecular medicine 2025 Jul;56(1)
International journal of molecular medicine 2025 Jul;56(1)
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells.
Xie Y, Qin Y, Wang J, Xu Z, Chen L, Kuang Y, Yang R, Huang L
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jul;398(7):8947-8962
Platelet-rich plasma improves cyclophosphamide-induced interstitial cystitis in rat models through the toll-like receptor 4/nuclear factor-kappa B signalling pathway.
Wu Y, Chen L, Xu M, Yao L, Yang S, Ang X, Chen W
Clinical and experimental nephrology 2025 Jul;29(7):995-1004
Clinical and experimental nephrology 2025 Jul;29(7):995-1004
Alpha-lipoamide prevents acute kidney injury in mouse by inhibiting renal tubular epithelial cell pyroptosis.
Tan WL, Yu X, Jia J, Chen RY, Xu XX, Liang LQ, Ruan YY, Wang FF, Chen YT, Peng YL, Peng J, Shi M, Tang L, Guo B, Wang YY
Biochemical pharmacology 2025 Jul;237:116942
Biochemical pharmacology 2025 Jul;237:116942
Discovery of a novel BCL-2 inhibitor GW806742X for the treatment of TNBC.
Liu W, Xu J, Chen L, Zhang D, Zhang J, Lu L, Zhang X, Huang X, Zhang G
Biochemical pharmacology 2025 Jul;237:116925
Biochemical pharmacology 2025 Jul;237:116925
Ji-Ming-San enhances intestinal circadian rhythms and mitigates colitis in mice: The role of epithelial RORα.
Pan Z, Liu J, Lin S, Li Z, Qin S, Wu H, Li F, Wu B, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156759
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156759
Bovine collagen peptides and peptide-calcium complexes inhibit RANKL-induced osteoclast differentiation in RAW 264.7 macrophages.
Liu Y, Zhu Y, Zhao Y, Wang J, Yu Y, Zhu J, Jin G
Journal of the science of food and agriculture 2025 Jul;105(9):4999-5008
Journal of the science of food and agriculture 2025 Jul;105(9):4999-5008
Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.
Bian Y, Li F, A X, Xiang Z, Ma N, Wang J, Cao B, Xin P, Cheng X, Liu C, Xiang B, Shen J, Lu Q, Xiao L
Chinese medicine 2025 Jul 8;20(1):109
Chinese medicine 2025 Jul 8;20(1):109
Mechanism of hydroxychloroquine in the treatment of obstetric antiphospholipid syndrome by inhibiting NETs-induced trophoblast pyroptosis.
Liu J, Xu M, Shen D, Wang X
Molecular biology reports 2025 Jul 7;52(1):679
Molecular biology reports 2025 Jul 7;52(1):679
Mechanism of Brucea javanica against multiple myeloma via TNF-NF-κB signaling.
Wang Y, Zhang A, Chen Y, Qi D, Peng C, Liang Z, Guo J, Gu Y, Li H
Scientific reports 2025 Jul 7;15(1):24311
Scientific reports 2025 Jul 7;15(1):24311
Macrophage-mimetic liposomes co-delivering ceria and Ac2-26 peptide for penumbra protection in ischemic stroke.
Bai L, Li N, Li H, Dai Y, Bai Y, Ma F, Sha D, Xia S, Xu Y, Cao X
Journal of nanobiotechnology 2025 Jul 5;23(1):488
Journal of nanobiotechnology 2025 Jul 5;23(1):488
Ginsenoside Rh2-Liposome Potentiate Vaccine Immunity through Enhanced MHC‑I Presentation.
Nie Q, Chen Z, Gong W, Cao W, Wang X, Liu Y, Zhang S, Yang Y, Meng Z
ACS omega 2025 Jul 29;10(29):31940-31953
ACS omega 2025 Jul 29;10(29):31940-31953
Parishin C Attenuates Oxidative Stress and Inflammation in HT22 Hippocampal Neurons and BV2 Microglia Through Nrf2 Signaling Pathway.
Wang Y, Wu W, Wu X, Shah BA, Lombardo M, Ye G
International journal of molecular sciences 2025 Jul 27;26(15)
International journal of molecular sciences 2025 Jul 27;26(15)
Liraglutide attenuates autoimmune myocarditis by inhibiting NLRP3 and NF-κb pathways.
Zhang L, Han L, Lu Y, Chen Q
Scientific reports 2025 Jul 26;15(1):27274
Scientific reports 2025 Jul 26;15(1):27274
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Su J, Yang H, Wang S, Wang X, Li W, Meng W, Sun J, Zhu Y
Veterinary research 2025 Jul 25;56(1):159
Veterinary research 2025 Jul 25;56(1):159
Investigation of the effect and mechanism of Fei Re Pu Qing powder in treating acute lung injury (ALI) by modulating macrophage polarization via serum pharmacology and network pharmacology.
Ye Y, Xie M, Nie H, Zhang G, Tu L, Ao M, Liang X, Yang C, Huang X, Mei Z, Xie Y, Liu Q
Journal of ethnopharmacology 2025 Jul 24;351:120089
Journal of ethnopharmacology 2025 Jul 24;351:120089
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Wang S, Zhu L, Wang Y, Han Y, Wang Q, Yang W, Zhao L, Zhang Y, Pei D, Huang W, Jin A, Lin Z, Piao J
Cell death & disease 2025 Jul 23;16(1):549
Cell death & disease 2025 Jul 23;16(1):549
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Tian S, Wu L, Zheng H, Cheng Z, Liu J, Liu M, Yu X, Tu J, Wu W
The journal of headache and pain 2025 Jul 22;26(1):165
The journal of headache and pain 2025 Jul 22;26(1):165
FGA, a new target of histone acetylation, inhibits apoptosis of granulosa cells in follicles.
Chen Y, Fang M, Duan W, Yang T, Fan H, Lv M, Zhang L, Jiang Y, Li S, Li N, Li J, Yuan X
Biological research 2025 Jul 2;58(1):43
Biological research 2025 Jul 2;58(1):43
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
Li R, Zhao M, Sun M, Wu Y, Miao C, Fangyu L, Wu M, Shi X, Lu J, Yue X
Cancer cell international 2025 Jul 2;25(1):249
Cancer cell international 2025 Jul 2;25(1):249
SIGLEC1 ubiquitination and degradation induced by MARCHF3 protects ARPE19 retinal cells from high glucose-induced oxidative stress, inflammation, and apoptosis.
Rong X, Jiang Y, Qi M, Gao W, Rao Y
International ophthalmology 2025 Jul 19;45(1):298
International ophthalmology 2025 Jul 19;45(1):298
Machine learning-based integration develops a hypoxia-derived signature for improving outcomes in glioma.
Zhou Q, Zhou Z, Guo Y, Yan X, Jiang X, Du C, Ke Y
iScience 2025 Jul 18;28(7):112023
iScience 2025 Jul 18;28(7):112023
Platelet NLRP6 protects against microvascular thrombosis in sepsis.
Jiang H, Chen S, Gui X, Li Y, Sun Y, Zhu H, Dai Y, Zhang J, Li X, Ju W, Li Z, Zeng L, Xu K, Qiao J
Blood 2025 Jul 17;146(3):382-395
Blood 2025 Jul 17;146(3):382-395
Engineered Exosomes Delivering bta-miR-223 Alleviate Staphylococcus aureus-Induced Mastitis in Mice via the TLR4/NF-κB Signaling Pathway.
Wang Y, Ouyang K, Nie Y, Yang J, Liao Y, Chen X, Wang H, Luo J, Sun J, Xi Q, Shen B, Chen T, Zhang Y
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17824-17832
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17824-17832
EIF4A3-induced circPRKAR1B promotes esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB induced CCL3 secretion.
Li S, Ma J, Jia W, Duan Y, Wang J, Zhang X, Han Y
Cancer cell international 2025 Jul 16;25(1):262
Cancer cell international 2025 Jul 16;25(1):262
Immune cell diversity and regenerative markers reveal interactions among macrophages, rodlet cells, and stem cells in the kidney of Poecilia sphenops.
Sayed RKA, Bakry M, Mokhtar DM
Scientific reports 2025 Jul 16;15(1):25879
Scientific reports 2025 Jul 16;15(1):25879
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Zheng H, Dong W, Qiu H, Gao S, Hou L, Dong J, Zhao P, Chen F
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Protective Effects of Ginseng Soluble Dietary Fiber and Its Fecal Microbiota Extract on Antibiotic-Induced Gut Dysbiosis Obese Mice.
Yang L, Hua M, Li D, Li F, He Y, Miao X, Sun M, Niu H, An F, Wang J, Yang M, Lu J, Xu H, Wang J
Journal of microbiology and biotechnology 2025 Jul 14;35:e2502013
Journal of microbiology and biotechnology 2025 Jul 14;35:e2502013
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Chen H, Li G, Deng L, Li S, Huang S, Lee SM, Nie X, Bian JS
Biological research 2025 Jul 10;58(1):48
Biological research 2025 Jul 10;58(1):48
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Zhang J, Zhan Y, Deng Z, Chen S, Yang R, Zhang Y, Fu H, Huang Q, Wu J, Gu Y, Xie J
Respiratory research 2025 Jul 10;26(1):238
Respiratory research 2025 Jul 10;26(1):238
Gut microbiota-derived indoleacetic acid attenuates neuroinflammation and neurodegeneration in glaucoma through ahr/rage pathway.
Wang N, Sun C, Yang Y, Zhang D, Huang L, Xu C, Wang M, Xu M, Yan T, Wu Y, Xu L, Ju Y, Sun H, Guo W
Journal of neuroinflammation 2025 Jul 10;22(1):179
Journal of neuroinflammation 2025 Jul 10;22(1):179
A Novel Effect of Id2 in Microglia TNFα Regulation.
Wang W, Asiru, Luo G, Chen Y, Cui Y, Ping S, Chen Y
Molecular neurobiology 2025 Jan;62(1):304-321
Molecular neurobiology 2025 Jan;62(1):304-321
Sirt1 blocks nucleus pulposus and macrophages crosstalk by inhibiting RelA/Lipocalin 2 axis.
Wei YF, Zhang HL, Li LZ, Lv Y, Li H, Li Z, Yu FL, Jiang T, Zhang TY, Xin F, Ma C, Ren YX
Journal of orthopaedic translation 2025 Jan;50:30-43
Journal of orthopaedic translation 2025 Jan;50:30-43
Downregulation of the immunoproteasome subunit PSMB8 attenuates sepsis-associated acute kidney injury through the NF-κB pathway.
Li M, Tong W, Dai C, Lu G, Jin D, Deng F
Immunobiology 2025 Jan;230(1):152862
Immunobiology 2025 Jan;230(1):152862
ROS Responsive Cerium Oxide Biomimetic Nanoparticles Alleviates Calcium Oxalate Crystals Induced Kidney Injury via Suppressing Oxidative Stress and M1 Macrophage Polarization.
He Y, Peng E, Ba X, Wu J, Deng W, Huang Q, Tong Y, Shang H, Zhong Z, Liu X, Zhang Y, Ye T, Yang X, Wang K, Xie Y, Jiang K, Xia D, Chen Z, Tang K
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Small (Weinheim an der Bergstrasse, Germany) 2025 Jan;21(3):e2405417
Highly oxygenated ent-abietane diterpenoid lactones from Euphorbia peplus and their anti-inflammatory activity.
Yan Y, Peng MY, Yang Y, Zhang ZB, Zhang LL, Tang L, Qin XJ, Cheng YY, Di YT, Hao XJ
Bioorganic chemistry 2025 Jan;154:107989
Bioorganic chemistry 2025 Jan;154:107989
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
Xu HZ, Chen FX, Li K, Zhang Q, Han N, Li TF, Xu YH, Chen Y, Chen X
Drug delivery and translational research 2025 Jan;15(1):269-290
Drug delivery and translational research 2025 Jan;15(1):269-290
Oxymatrine, a novel TLR2 agonist, promotes megakaryopoiesis and thrombopoiesis through the STING/NF-κB pathway.
Ni C, Zhou L, Yang S, Ran M, Luo J, Cheng K, Huang F, Tang X, Xie X, Qin D, Mei Q, Wang L, Xiao J, Wu J
Journal of pharmaceutical analysis 2025 Jan;15(1):101054
Journal of pharmaceutical analysis 2025 Jan;15(1):101054
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
Shuhan W, Jinxiao L, Luorui S, Liuying C, Fangyuan Z, Mengqi Z, Qifeng L, Yuju C, Junli Z, Yao W, Shenglan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
Echinacoside attenuates Klebsiella pneumoniae-induced pneumonia via inhibition of the TLR4/NF-κB signaling.
Zhang M, Zhan M, Song X
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Jan;133(1):e13507
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2025 Jan;133(1):e13507
Protective Effects of α-Linolenic Acid on Liver Inflammation and Oxidative Stress Induced by Lipopolysaccharide in Broilers.
Cheng X, Zhang X, Ni J, Ding H, Ma W, Wang D
Animal science journal = Nihon chikusan Gakkaiho 2025 Jan-Dec;96(1):e70096
Animal science journal = Nihon chikusan Gakkaiho 2025 Jan-Dec;96(1):e70096
Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells.
Lin Z, Zhou Y, Chen R, Tao Q, Lu Q, Xu Q, Yu H, Jiang P, Zhao Z
Marine drugs 2025 Jan 9;23(1)
Marine drugs 2025 Jan 9;23(1)
Ellagic acid alleviates DSS-induced ulcerative colitis by inhibiting ROS/NLRP3 pathway activation and modulating gut microbiota in mice.
Xiong Y, Cheng Z, Zhang Y, Liu T, Wan Z, Xia C, Zhou B, Shan C, Song D, Miao F
European journal of nutrition 2025 Jan 7;64(1):64
European journal of nutrition 2025 Jan 7;64(1):64
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
Ling F, Chen Y, Li J, Xu M, Song G, Tu L, Wang H, Li S, Zhu L
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
G(1-5)-EM2, a multi-targeted agonist to opioid and growth hormone secretagogue receptors exhibited nontolerance forming antinociceptive effects in a mouse model of burn pain.
Cheng S, Ding J, Xu B, Wang Y, Shen X, Xia Y, Wu L, Wei J
European journal of pharmacology 2025 Jan 5;986:177148
European journal of pharmacology 2025 Jan 5;986:177148
Regulator of G protein signaling-1 facilitates ovarian cancer development by modulating NF-kB signal pathway.
Shengnan L, Jiayan X, Meng S, Li L, Shengyun C, Mingjuan X
Scientific reports 2025 Jan 5;15(1):864
Scientific reports 2025 Jan 5;15(1):864
Classical prescription Daqinjiao decoction inhibit cerebral ischemia/reperfusion induced necroptosis and ferroptosis through multiple mechanisms.
Liu Y, Liu J, Hu N, Li Z, Liu A, Luo R, Du S, Guo D, Li J, Duan J
Journal of ethnopharmacology 2025 Jan 31;340:119300
Journal of ethnopharmacology 2025 Jan 31;340:119300
The structural features and anti-inflammatory properties of a glucogalactan from Holotrichia diomphalia Bates (Qi Cao).
Liu WJ, Xu DQ, Cui DX, Fu RJ, Jing H, Li XQ, Cao W, Tang YP
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118948
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118948
Taxus chinensis (Pilg.) Rehder fruit attenuates aging behaviors and neuroinflammation by inhibiting microglia activation via TLR4/NF-κB/NLRP3 pathway.
Meimei C, Fei Z, Wen X, Huangwei L, Zhenqiang H, Rongjun Y, Qiang Z, Qiuyang L, Xiaozhen L, Yuan Y, Zhaoyang Y, Candong L
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118943
Extract of Tinospora sinensis alleviates LPS-induced neuroinflammation in mice by regulating TLR4/NF-κB/NLRP3 signaling pathway.
Xie Y, Fang C, Lu L, Wang J, Wu L, Wang S, Guo Q, Yan W, Wei J, Duan F, Huang L
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118807
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118807
Huang-Lian-Jie-Du Decoction alleviates diabetic encephalopathy by regulating inflammation and pyroptosis via suppression of AGEs/RAGE/NF-κB pathways.
Zhuang GD, Deng SM, Chen MD, Deng CF, Gu WT, Wang SM, Tang D
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118787
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118787
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota.
Li B, Liu M, Du W, Wang S, Xu Z, Zhang X, Zhang Y, Hua S
BMC veterinary research 2025 Jan 29;21(1):39
BMC veterinary research 2025 Jan 29;21(1):39
Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson's disease.
Qiao CM, Tan LL, Ma XY, Xia YM, Li T, Li MA, Wu J, Nie X, Cui C, Zhao WJ, Shen YQ
International immunopharmacology 2025 Jan 27;146:113938
International immunopharmacology 2025 Jan 27;146:113938
Identification of glutamine as a potential therapeutic target in dry eye disease.
Chen X, Zhang C, Peng F, Wu L, Zhuo D, Wang L, Zhang M, Li Z, Tian L, Jie Y, Huang Y, Yang X, Li X, Lei F, Cheng Y
Signal transduction and targeted therapy 2025 Jan 22;10(1):27
Signal transduction and targeted therapy 2025 Jan 22;10(1):27
Piezo1 promotes vibration-induced vascular smooth muscle injury by regulating the NF-κB/p65 axis.
Zeng Y, Wu Z, Xiong M, Liang Z, Chen Z, Huang H, Yang H, Chen Q
Communications biology 2025 Jan 21;8(1):96
Communications biology 2025 Jan 21;8(1):96
Dual neutralization of TGF-β and IL-21 regulates Th17/Treg balance by suppressing inflammatory signalling in the splenic lymphocytes of Staphylococcus aureus infection-induced septic arthritic mice.
Pramanik R, Chattopadhyay S, Bishayi B
Immunologic research 2025 Jan 20;73(1):38
Immunologic research 2025 Jan 20;73(1):38
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
Zhang H, Zhang Y, Zhang Y, Wei H, Jin S, Huo T, Qin L
Food & function 2025 Jan 20;16(2):673-690
Food & function 2025 Jan 20;16(2):673-690
tRNA-derived fragment 3031B regulates human anterior cruciate ligament cell proliferation and survival by targeting RELA.
Long D, Deng Z, Li M, Li W, Zhong Y, Lin Z, He A, Kang Y, Mao G
Gene 2025 Jan 15;933:148897
Gene 2025 Jan 15;933:148897
CUMS induces depressive-like behaviors and cognition impairment by activating the ERS-NLRP3 signaling pathway in mice.
Hao R, Gao X, Lu Q, Zhao T, Lu X, Zhang F, Pei Y, Lang J, Liu H, Song J, Zhang Z
Journal of affective disorders 2025 Jan 15;369:547-558
Journal of affective disorders 2025 Jan 15;369:547-558
α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation.
Wang H, Zhang H, Miao L, Wang C, Teng H, Li X, Zhang X, Yang G, Wang S, Zeng X
Ecotoxicology and environmental safety 2025 Jan 15;290:117749
Ecotoxicology and environmental safety 2025 Jan 15;290:117749
Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice.
Xiong Z, Kong Q, Hua J, Chen Q, Wang D
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
Ecotoxicology and environmental safety 2025 Jan 15;290:117712
Diosmetin-7-O-β-D-glucopyranoside from Pogostemonis Herba alleviated SARS-CoV-2-induced pneumonia by reshaping macrophage polarization and limiting viral replication.
Xu YL, Li XJ, Cai W, Yu WY, Chen J, Lee Q, Choi YJ, Wu F, Lou YJ, Ying HZ, Yu CH, Wu QF
Journal of ethnopharmacology 2025 Jan 10;336:118704
Journal of ethnopharmacology 2025 Jan 10;336:118704
Human leukocyte antigen DR alpha inhibits renal cell carcinoma progression by promoting the polarization of M2 macrophages to M1 via the NF-κB pathway.
Xiong F, Wang B, Zhang H, Zhang G, Liu Y, Liu Y, Wang C
International immunopharmacology 2025 Jan 10;144:113706
International immunopharmacology 2025 Jan 10;144:113706
Marein ameliorates the progression of osteoarthritis: An in vitro and in vivo studies.
Yin L, He Z, Fan Y, Niu Z, Yao L, Ding S, Chen J, Zhang Q, Tong Y, Bi Q, Cao L
International immunopharmacology 2025 Jan 10;144:113695
International immunopharmacology 2025 Jan 10;144:113695
Long-term copper exposure induced pyroptosis and inflammation of rat spleen through intestinal-splenic axis.
Quan J, Chang X, Liu S, He T, Zhong G, Liu Z, Yu W
Ecotoxicology and environmental safety 2025 Jan 1;289:117423
Ecotoxicology and environmental safety 2025 Jan 1;289:117423
Synthesis and biological evaluation of lappaconitine analogues as potential anti-neuroinflammatory agents by side chain modification and scaffold hopping strategy.
Xing F, Su HY, Zhong HY, Li YZ, Zhang YY, Chen L, Zhou XL
Bioorganic & medicinal chemistry 2025 Jan 1;117:118012
Bioorganic & medicinal chemistry 2025 Jan 1;117:118012
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen-glucose deprivation/reoxygenation.
Deng Y, Wang G, Hou D, Zhang L, Pei C, Yang G
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):178-188
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):178-188
Inhibition of DNA Methyltransferase DNMT1 Reverses Th2 Response Polarisation and Alleviates Allergic Rhinitis.
Zou P, Li J, Li J, Wang J
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
Clinical and experimental pharmacology & physiology 2025 Feb;52(2):e70015
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
Wei H, Zhang Y, Gao M, Yang J, Wang S, Zhou X, Wei H, Xiao F
Molecular and cellular biochemistry 2025 Feb;480(2):1183-1195
Molecular and cellular biochemistry 2025 Feb;480(2):1183-1195
Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling.
Chen J, Sheng R, Mo Q, Backman LJ, Lu Z, Long Q, Chen Z, Cao Z, Zhang Y, Liu C, Zheng H, Qi Y, Cao M, Rui Y, Zhang W
Bioactive materials 2025 Feb;44:319-338
Bioactive materials 2025 Feb;44:319-338
Uncovering the mechanisms of diosmin in treating obesity-related kidney injury based on network pharmacology, molecular docking, and in vitro validation.
Zhu JX, Chu F, Zhao WM, Shi R, Wang ZJ, Li XL, Zhu YY, Wang DG
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1973-1989
Naunyn-Schmiedeberg's archives of pharmacology 2025 Feb;398(2):1973-1989
Multi-omics analysis explore the mechanism of deoxynivalenol inhibiting rabbit appetite through microbial-gut-brain axis.
Yuan X, Chen W, Li R, Guo H, Wang C
Ecotoxicology and environmental safety 2025 Feb;291:117849
Ecotoxicology and environmental safety 2025 Feb;291:117849
Lauric acid-mediated gelatin/hyaluronic acid composite hydrogel with effective antibacterial and immune regulation for accelerating MRSA-infected diabetic wound healing.
Yang J, Wang D, Yu H, Wang L, Wang Y, Liu X, Huang Y, Ouyang C, Hong Y, Ren S, Wang Y, Jin Y, Hu J, Feng J
International journal of biological macromolecules 2025 Feb;290:138792
International journal of biological macromolecules 2025 Feb;290:138792
Melatonin alleviates oxidative stress and inflammation of Leydig cells of Min pig through SIRT1 pathway.
Chen Y, Tang Y, Liu B, Wang J, Wang H, Li B, Liu S, Adeniran SO, Zheng P
Theriogenology 2025 Feb;233:112-122
Theriogenology 2025 Feb;233:112-122
Exploring the effects of lactulose on lung-intestinal tissue-associated factors and the TLR4/NF-κB signaling pathway in COPD rats based on lung-gut axis theory.
Liu X, Ding R, Wu K, Zhang A, Fan H, Yang J, Li M
Microbial pathogenesis 2025 Feb;199:107245
Microbial pathogenesis 2025 Feb;199:107245
Molecular insights of T-2 toxin exposure-induced neurotoxicity and the neuroprotective effect of dimethyl fumarate.
Pei X, Ma S, Hong L, Zuo Z, Xu G, Chen C, Shen Y, Liu D, Li C, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115166
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115166
Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential.
Sun X, Wan J, Zhang Y, Shen Y, Tang Y, Yin Y, Chamley LW, Zhao M, Chen Q
Placenta 2025 Feb;160:20-28
Placenta 2025 Feb;160:20-28
Integration of transcriptomics and metabolomics reveals the mechanism of Glycyrrhizae Radix Et Rhizoma extract inhibiting CCL5 in the treatment of acute pharyngitis.
Han X, Sun C, Ding H, Deng S, Li M, Lou J, Song X, Kai G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156360
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156360
Donkey milk supplementation alleviates renal fibrosis of chronic kidney disease by enhancing anti-inflammatory ability.
Huimin C, Peng W, Man C, Hong L, Yuxin Z, Zhiyu P, Jianjun Y
Journal of dairy science 2025 Feb;108(2):1198-1210
Journal of dairy science 2025 Feb;108(2):1198-1210
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Li W, Wang X, Chen K, Zhu Y, Yang G, Jin Y, Wang J
Veterinary research 2025 Feb 8;56(1):35
Veterinary research 2025 Feb 8;56(1):35
Repressing cytokine storm-like response in macrophages by targeting the eIF2α-integrated stress response pathway.
Wang X, Dai C, Cheng W, Wang J, Cui X, Pan G, Chen Y, Han Y, Guo X, Jiang F
International immunopharmacology 2025 Feb 6;147:113965
International immunopharmacology 2025 Feb 6;147:113965
Fraxin inhibits ovariectomized-induced bone loss and osteoclastogenesis by suppressing ROS activity.
Zhou H, Chen P, Zhao C, Zou S, Wu H, Huang C, Hu H, Wu Q, Zhang C, Weng W
International immunopharmacology 2025 Feb 6;147:113871
International immunopharmacology 2025 Feb 6;147:113871
Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways.
Zhu L, Bi Y, Liang T, Zhang P, Xiao X, Yu T
Journal of orthopaedic surgery and research 2025 Feb 5;20(1):139
Journal of orthopaedic surgery and research 2025 Feb 5;20(1):139
Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1.
Li G, Huang L, Gu D, Wang P, Yi L, Kuang W, Zhang Y, Zhang J, Liu D, Shi Q, Tang H, Sun J, Zeng G, Peng X, Wang J
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
Cell communication and signaling : CCS 2025 Feb 3;23(1):62
RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via the PI3K-AKT signaling pathway.
Sheng T, Su H, Yao L, Qu Z, Liu H, Shao W, Zhang X
BMC cancer 2025 Feb 26;25(1):354
BMC cancer 2025 Feb 26;25(1):354
Exosomal miR-203 from bone marrow stem cells targets the SOCS3/NF-κB pathway to regulate neuroinflammation in temporal lobe epilepsy.
Wang W, Yin J
World journal of stem cells 2025 Feb 26;17(2):101395
World journal of stem cells 2025 Feb 26;17(2):101395
Long non-coding RNA NRIR inhibits osteogenesis in peri-implantitis by promoting NLRP3 inflammasome-mediated macrophage pyroptosis.
Wang L, Zhao R, Xiao K, Zhou Y, Liu Q, Yu K
International immunopharmacology 2025 Feb 20;148:114180
International immunopharmacology 2025 Feb 20;148:114180
Structural Characterization of APSN from Astragalus membranaceus and Its Potential Therapeutic Effect on Immune Dysregulation and Tissue Damage.
Hu L, Sun Q, Liu Z, Huang H, Zhao E, Chen H, Wu Y, Ge Y, Ouyang D, Tang B
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4042-4054
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4042-4054
L-Theanine Mitigates Acute Alcoholic Intestinal Injury by Activating the HIF-1 Signaling Pathway to Regulate the TLR4/NF-κB/HIF-1α Axis in Mice.
Tan S, Gu J, Yang J, Dang X, Liu K, Gong Z, Xiao W
Nutrients 2025 Feb 18;17(4)
Nutrients 2025 Feb 18;17(4)
Pulsed electromagnetic field ameliorates the progression of osteoarthritis via the Sirt1/NF-κB pathway.
Zhou S, Wen H, He X, Han X, Li H
Arthritis research & therapy 2025 Feb 14;27(1):33
Arthritis research & therapy 2025 Feb 14;27(1):33
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses.
Li P, Zhang R, Hu P, Wang T, Wang J
Journal of ethnopharmacology 2025 Feb 11;341:119358
Journal of ethnopharmacology 2025 Feb 11;341:119358
Jiawei Ermiao Granules (JWEMGs) clear persistent HR-HPV infection though improving vaginal microecology.
Li X, Ning L, Zhao H, Gu C, Han Y, Xu W, Si Y, Xu Y, Wang R, Ren Q
Journal of ethnopharmacology 2025 Feb 11;341:119342
Journal of ethnopharmacology 2025 Feb 11;341:119342
Investigating the possible mechanism of Cornus officinalis in the therapy of ischemic stroke by UHPLC-Q-TOF-MS, network pharmacology, molecular docking, and experimental verification.
Zhang Y, Yuan PP, Li PY, Zheng YJ, Li SF, Zhao LR, Ma QY, Cheng JL, Ma JS, Feng WS, Zheng XK
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119072
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119072
Chronic treatment of mixture of two iridoids proportional to prescriptional dose of Yueju improves hippocampal PACAP-related neuroinflammation and neuroplasticity signaling in the LPS-induced depression model.
Wu Z, Yin Y, Liu R, Li X, Wang Z, Wu C, Tan J, Fu Z, Song C, Lee Wong N, Peng X, Lai S, Cui J, Han M, Peng Y, Sun Y, Wu L, Adzic M, Zeng L, Zhang H, Yau SY, Chen G
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119031
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119031
4D-DIA-based proteomics analysis reveals the protective effects of Pidanjiangtang granules in IGT rat model.
Xie Y, Fan Y, Liu X, Li Z, Liu S
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119012
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119012
Carboxymethyl chitosan and sodium alginate oxide pH-sensitive dual-release hydrogel for diabetes wound healing: The combination of astilbin liposomes and diclofenac sodium.
Wu X, Wang Y, Liu X, Ding Q, Zhang S, Wang Y, Chai G, Tang Y, Yang J, Yu T, Liu W, Ding C
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
Carbohydrate polymers 2025 Feb 1;349(Pt B):122960
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Huo Y, Shen T, Feng T, Li M, Zhao W, Loor JJ, Aernouts B, Psifidi A, Xu C
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Indirubin regulates M1/M2 polarization and inhibits ferroptosis in dextran sulfate sodium induced colitis and in cultured THP-1 cells.
Huang YX, Zhang JR, Fu SH, Liu Z, Zhong HJ, Zhong QY, Luo YD, Hu YJ, Zhu HP, Wen B, Chen S
Pharmaceutical biology 2025 Dec;63(1):698-715
Pharmaceutical biology 2025 Dec;63(1):698-715
Propofol inhibits glioma growth by blocking the formation of the NF-κB/LGI4 feedback loop to activate TP53 self-transcription.
Wang Z, Zhang LN, Wu T, Pan X, Li L
Translational oncology 2025 Dec;62:102578
Translational oncology 2025 Dec;62:102578
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Jie L, Zhang Y, Liu J, Fu H, Zhu Z, Huang Z, Shi X, Wang P, Yin S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
HNRNPC-Mediated m6A Epitranscriptomics Drives CD80-Dependent Tubular Dysfunction in Sepsis-Induced AKI.
Juan C, Zhao X, Wang Y, Chen D, Yu M, Mao Y
Inflammation 2025 Dec;48(6):4591-4607
Inflammation 2025 Dec;48(6):4591-4607
Alpha Ketoglutaric Acid attenuates LPS Induced Inflammatory Response by Inhibiting the PKCε/MAPK/P65 Signaling Pathway and Inhibit Oxidative Stress in Kupffer Cells.
Li Y, Kuang H, Fan G, Yang X
Inflammation 2025 Dec;48(6):4020-4030
Inflammation 2025 Dec;48(6):4020-4030
TAK-981 potentiates doxorubicin immunocide in triple-negative breast cancer by IFN I-dependent NK cell stimulation.
Liu J, Wang Y, Wei X, Liu S, Hu C, Peng P, Wu W, Cai J, Sun H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1871-1887
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1871-1887
The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma.
Wu D, Wang AJ, Bu DC, Sun YY, Li CH, Hong YM, Zhang S, Chen SY, Zhou JA, Zhang TY, Yu MH, Ma YJ, Wang XL, Xu J, He W, Heeschen C, Chen JF, Mao WJ, Ding H, Wu WJ, Zhao Y, Wang H, Liu NN
iMeta 2025 Dec;4(6):e70090
iMeta 2025 Dec;4(6):e70090
Intelligent responsive PVA hydrogel loaded with composite MXene nanozyme enables efficient myocardial infarction repair by disrupting the oxidative stress-inflammation cascade.
Tong J, Sun D, Sun J, Zhang J, Chen M, Liu X, Zhang R, Zhang F, Zheng C, Wei Y, Guo X
Materials today. Bio 2025 Dec;35:102556
Materials today. Bio 2025 Dec;35:102556
Pan-cancer analysis identifies adhesion G protein-coupled receptor G6 as a potential prognostic and immunotherapeutic biomarker with its functional validation.
Zhu J, Wang Y, Huang Q, Liu Z
International journal of biological macromolecules 2025 Dec;334(Pt 2):149128
International journal of biological macromolecules 2025 Dec;334(Pt 2):149128
Acute carbon monoxide poisoning induces renal inflammation and apoptosis via CCL4 upregulation and activation of the PI3K/Akt pathway in mice.
Ni Y, Jiang X, Wang S, Pu T, Yan T, Yu A, Liu Q
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Fatty acid synthesis promotes mtDNA release via ETS1-mediated oligomerization of VDAC1 facilitating endothelial dysfunction in sepsis-induced lung injury.
He S, Pan T, Tian R, He Q, Cheng D, Qu H, Li R, Tan R
Cell death and differentiation 2025 Dec;32(12):2177-2192
Cell death and differentiation 2025 Dec;32(12):2177-2192
Indole modulates lipoteichoic acid-induced inflammatory response in duck intestinal epithelial cells.
Yan W, Zhu A, Zhong B, Chen Q
Microbial pathogenesis 2025 Dec;209:108030
Microbial pathogenesis 2025 Dec;209:108030
Pyridostigmine attenuates placental-ischemia-upregulated placental angiotensin II type 1 receptor in rats.
Issotina Zibrila A, Alkuhali AA, Yuan M, Zeng Z, Ali MA, Zeng M, Elenany AM, Manzoor M, Wang X, Zhao M, Jin L, Liu J
Peptides 2025 Dec;194:171450
Peptides 2025 Dec;194:171450
Trimethylamine-N-oxide damages astrocytes and lymphatic endothelial cells in the cerebral lymphatic system.
Su ML, Duan HS, Wang QL, Zhang Y, Shi XM, Zeng J, Tan WN, Chang Y, Wang S
IBRO neuroscience reports 2025 Dec;19:614-623
IBRO neuroscience reports 2025 Dec;19:614-623
E3 ubiquitin ligase Pellino1 suppresses acinar cell necroptosis and alleviates severe acute pancreatitis by promoting ubiquitin-dependent receptor-interacting protein kinase 3 (RIP3) degradation.
Chen J, Huang Z, Jing P, Shi H, Liu S, Feng L, Long Y, Ye M, Fu W, Tan P
British journal of pharmacology 2025 Dec;182(24):6100-6119
British journal of pharmacology 2025 Dec;182(24):6100-6119
The Therapeutic Potential of Lactobacillus crispatus for Chronic Endometritis: A Comprehensive Clinical Trial and Experimental Investigation.
He X, Chen W, Zhou X, Hu G, Wei J, Liu Y, Cai L, Zhang Z, Chen T
Probiotics and antimicrobial proteins 2025 Dec;17(6):4047-4065
Probiotics and antimicrobial proteins 2025 Dec;17(6):4047-4065
Eukaryotic translation elongation factor 1 alpha 1 facilitates coxsackievirus B replication through interacting with PABP, viral protein 3 CD and viral RNA.
Zhao S, Dong Y, Wang Y, Yang H, Luan T, He Y, Lin L, Chen Y, Fei Y, Wang G, Wang Y, Zhong Z, Qi N, Zhao W
Virulence 2025 Dec;16(1):2563925
Virulence 2025 Dec;16(1):2563925
Silybin ameliorates Pb-induced learning and memory impairment by inhibiting STAT3/hnRNP U/REST and NFκB/hnRNP U.
Zhang W, Chen H, Li Y, Zhu Q, Liu K, Liu X, Wang Y, Zhu G
Environmental toxicology and pharmacology 2025 Dec;120:104859
Environmental toxicology and pharmacology 2025 Dec;120:104859
Disruption of NF-κB-Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis.
Zhang X, Su Y, Yang W, Song Z, Sun Z, Wu X, Chen J, Gao B, Wang Z, Wang L, Jiang Q, Bu L, Li J, Lin Y, Xie W, Li J, Guo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(47):e06201
Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR-NFκB Pathway.
Chen J, Liu N, Tao Q, Wu J, Huang J, Lu C, Li Q, Shen L, Chen X, Peng C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e06139
Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells.
Yang Y, Li M, Wang J, Zhang H, Chang R, Zhao B, Aernouts B, Huang Q, Xu C
Journal of dairy science 2025 Dec;108(12):13919-13937
Journal of dairy science 2025 Dec;108(12):13919-13937
Hesperidin-β-Cyclodextrin inclusion complexes: A novel approach for preventing and treating acute lung injury caused by seawater drowning.
Hou J, Zhang M, Han Z, Wang W, Qiu H, Yuan J, An F, Wu Y
International journal of pharmaceutics: X 2025 Dec;10:100379
International journal of pharmaceutics: X 2025 Dec;10:100379
FUT3-B3GNT3 interaction promotes pancreatic cancer progression and chemoresistance via NF-κB signaling mediated autophagy.
Jin L, Han W, Zou J, Tang X, Chen P, Xie H, Zhou B, Qian D, Yu Y
European journal of medical research 2025 Dec 9;30(1):1223
European journal of medical research 2025 Dec 9;30(1):1223
Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis.
Zhang T, Li R, Wang Z, Zhou Y, Zhou Y, Chen X, Peng C, Jiang Y, Tong N, Li W
Nature communications 2025 Dec 8;17(1):495
Nature communications 2025 Dec 8;17(1):495
Fisetin carbon dots alleviate periodontitis by enhancing mitophagy through regulation of sirtuin 3 SUMOylation.
Deng Y, Jiang X, Che Z, Shang Y, Hu M, Wang W, Yu W, Yang B, Liu X
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Journal of nanobiotechnology 2025 Dec 6;23(1):767
Taurine Attenuates M1 Macrophage Polarization and IL-1β Production by Suppressing the JAK1/2-STAT1 Pathway via Metabolic Reprogramming.
Zhang Z, Li D, He S, Xu W, Lv Q, Wang Y, Xu J, Yu Z, Liu S, Ge Y, Shi F, Yan Y
Biology 2025 Dec 6;14(12)
Biology 2025 Dec 6;14(12)
Neutrophil-macrophage crosstalk via NETs-IL-17/VEGF/S100A9 axis promotes hepatocellular carcinoma progression.
Wu R, Wu R, Kong X, Wang X, Duan Y, Cao S, Yu S, Zhao Y, Li S, Zhou J, Duan L
Journal of experimental & clinical cancer research : CR 2025 Dec 30;45(1):27
Journal of experimental & clinical cancer research : CR 2025 Dec 30;45(1):27
Complement C4b as a key mediator of synaptic loss and cognitive decline in brain aging.
Zheng Y, Liu T, Luo L, Li F, Tang C, Xu C, Chen C, Yang L, Xiao Y, Wang Z, Yuan Q, Zheng M, Li H, Yang J
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Dec 3;33(12):6314-6331
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Dec 3;33(12):6314-6331
Butin inhibits osteoarthritis progression by modulating the Nrf2/HO-1 signaling pathway and inhibiting NF-κB signaling.
Zhou P, Chang J, Wei X, Zhu C, Yang J, Wang C, Hu Y, Zhang C
Scientific reports 2025 Dec 26;15(1):45688
Scientific reports 2025 Dec 26;15(1):45688
Effects of psychosocial stress on myocardial injury by modulating endoplasmic reticulum stress-induced autophagy and inflammation.
Gao X, Huang G, Hao R, Wang L, Ma A, Zhang Z, Zhao T
iScience 2025 Dec 19;28(12):114022
iScience 2025 Dec 19;28(12):114022
Interleukin-27 is a multitarget regulator of fibroblast remodeling in thyroid-associated ophthalmopathy.
Zhang P, Wang X, Lu N, Nie Y, Zhang X, Liu L
iScience 2025 Dec 19;28(12):113982
iScience 2025 Dec 19;28(12):113982
Expression and Biological Activity of Recombinant Type IV Collagen.
Chang Y, Zhang Z, Yuwen W, Xu R, Fu R, Zhu C, Li W, Duan Z, Fan D
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31865-31877
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31865-31877
CEBPD-mediated SGPP2 upregulation via PERK/ER stress in endothelial cells disrupts S1P homeostasis and impairs angiogenesis in chronic endometritis.
Wang Y, Chen X, You G, Yu S, Chen C, Lian R, Diao L, Li Y, Yin T
Journal of translational medicine 2025 Dec 17;24(1):98
Journal of translational medicine 2025 Dec 17;24(1):98
Hedyotis diffusae herba -Scutellaria Barbata herba drug pair suppresses prostate cancer by inducing apoptosis.
Qiu J, Wu L, Hong Z, Shi Y, Wei Y, Wang Q, Chen Z, Chen W, Zhang Q, You XJ, Zhou WB, Zhou W
Scientific reports 2025 Dec 17;16(1):2938
Scientific reports 2025 Dec 17;16(1):2938
Denosumab attenuates knee osteoarthritis progression by inhibiting synovial inflammation via the RANK/TRAF6/FSTL1 signalling.
Hu Y, Chen W, Lan S, Ming C, Xu D, Li H, Xu H, Shi D, Liu W, Dai Z, Wang J, He Z, Xu W, Shao Z, Liu Y, Tian H, Tong W
Nature communications 2025 Dec 17;16(1):11394
Nature communications 2025 Dec 17;16(1):11394
18β-glycyrrhetinic acid-amantadine hybrid: Synthesis and anti-EMCV activity via NF-κB modulation.
Xue W, Zhang T, Wen Y, Zhang Y, Hou J, Zhao J, Feng R, Tan C
Bioorganic & medicinal chemistry 2025 Dec 15;131:118431
Bioorganic & medicinal chemistry 2025 Dec 15;131:118431
Triptolide combined with arsenic trioxide induces apoptosis of myelodysplastic syndrome cells by inhibiting the NF-κB signaling pathway.
Sheng L, Zhu Y, Wen Z, Fang M, Gu S, Ye L, Hua H
Medicine 2025 Dec 12;104(50):e46206
Medicine 2025 Dec 12;104(50):e46206
Fennel essential oil and its nanoemulsion modulate macrophage-mediated inflammatory responses and promote pressure ulcer healing.
Luo Z, Zeng L, Zhao Z, Zheng Y, Wan D
International immunopharmacology 2025 Dec 10;167:115631
International immunopharmacology 2025 Dec 10;167:115631
Resolvin D1 Modulates the Inflammatory Processes of Human Periodontal Ligament Cells via NF-κB and MAPK Signaling Pathways.
Yan J, Cai J, Pan X, Li S, Fenton CG, Fenton KA, Kantarci A, Xue Y, Xue Y, Xing Z
Biomedicines 2025 Dec 10;13(12)
Biomedicines 2025 Dec 10;13(12)
Effect of Limosilactobacillus reuteri SBC5-3 Cell-free Supernatant on Growth Performance, Intestinal Inflammation, and Microbiota in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88.
Xu L, Bao G, Chen S, Liu C, Zi X, Hu M, Liu Q, Lin Q, Cao Z
Probiotics and antimicrobial proteins 2025 Dec 10;
Probiotics and antimicrobial proteins 2025 Dec 10;
Auranofin facilitates gemcitabine sensitivity by regulating TXNRD1-related ferroptosis in pancreatic ductal adenocarcinoma.
Lu SY, Fang DL, Zhao ZY, Zhu YQ, Liu ZD, Ma MJ, Ye JY, Xu QC, Yin XY
Cancer letters 2025 Dec 1;634:218058
Cancer letters 2025 Dec 1;634:218058
RPPH1 promotes the progression of High-Risk acute myeloid leukemia through NF-κB signaling and Th17 expression.
Wang M, Li W, Luo C, Cao Y, Lu Z, Zhu J, Xiang M, Liao P, Li J
Medical oncology (Northwood, London, England) 2025 Dec 1;43(1):30
Medical oncology (Northwood, London, England) 2025 Dec 1;43(1):30
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
Yu JT, Hu XW, Wang JN, Yang Q, Li XY, Shan RR, Pu T, Hou R, Shen XY, Wang YQ, Zhang F, Yu XW, Wang J, Li FH, Wen JG, Fan Y, Jin J, Jiang YY, Meng XM
Nature communications 2025 Dec 1;17(1):30
Nature communications 2025 Dec 1;17(1):30
Exosomes Derived From Calycosin-Exposed Prostate Stromal Cells Inhibit Lipopolysaccharide-Induced Epithelial Cells Inflammatory Injury.
Li M, Yao W, Sun Y, Wang H
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Aug;94(2):e70113
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Aug;94(2):e70113
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
Chen P, Gong Q, Wang H, Wang C, Wang W, Wu J, Wu Z, Wang L
Molecular neurobiology 2025 Aug;62(8):10210-10227
Molecular neurobiology 2025 Aug;62(8):10210-10227
NOD3 Reduces Sepsis-Induced Acute Lung Injury by Regulating the Activation of NLRP3 Inflammasome and the Polarization of Alveolar Macrophages.
Zhao Y, Wu Y, Qu L, Hu Y, Sun S, Yao R, Li R
Inflammation 2025 Aug;48(4):2395-2406
Inflammation 2025 Aug;48(4):2395-2406
Polyphenol-based self-assembled nanoparticles treating uveitis by inflammation-oxidative stress suppression.
Chen H, Yang Q, Li M, Ren M, Liu S, An G, Ren Y, Liu P, Du L, Sun X, Jin X
Materials today. Bio 2025 Aug;33:102052
Materials today. Bio 2025 Aug;33:102052
IFI16 Induced by p53 Activates the NF-κB Pathway to Counteract Cisplatin-Induced Apoptosis in Cervical Cancer Cells.
Zhong L, Li J, Zhong J, Zhang Y, Qi H, Yu H, Li X
Journal of cellular and molecular medicine 2025 Aug;29(15):e70728
Journal of cellular and molecular medicine 2025 Aug;29(15):e70728
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Li J, Zeng S, Zhou B, Yan Q, Sun Y, Chen L, Zhang E, Li J
Biochemical pharmacology 2025 Aug;238:116980
Biochemical pharmacology 2025 Aug;238:116980
Ghrelin/GHSR system attenuates collagen-induced arthritis in mice and ameliorates inflammation in human rheumatoid arthritis fibroblast-like synoviocytes.
Ma J, Zhang J, Liu J, Zhao J, Wang X, Li Z, Lv T, Zhang Y
Biochemical pharmacology 2025 Aug;238:116973
Biochemical pharmacology 2025 Aug;238:116973
BPA Exacerbates Zinc Deficiency-Induced Testicular Tissue Inflammation in Male Mice Through the TNF-α/NF-κB/Caspase8 Signaling Pathway.
Wang X, Ma J, Li W, Hou Z, Li H, Li Y, Wang S, Tie Y
Biological trace element research 2025 Aug;203(8):4153-4163
Biological trace element research 2025 Aug;203(8):4153-4163
The β2-adrenergic receptor modulates activity of porcine alveolar macrophages in response to Actinobacillus pleuropneumoniae infection.
Xing W, Shi H, Wu W, Lu S, Fu H, Lu J, Li S, Xu B
Developmental and comparative immunology 2025 Aug;169:105420
Developmental and comparative immunology 2025 Aug;169:105420
Targeting Reticulin 4 (RTN4) Within Small Extracellular Vesicles Combats Metastasis and Reinforces Immunotherapy in Triple-Negative Breast Cancer.
Wang H, Huang R, Luo L, Wang R, Zhou Z, Hong J, Wu J, Huang O, He J, Chen W, Li Y, Chen X, Wang Y, Wang Z, Shen K
Journal of extracellular vesicles 2025 Aug;14(8):e70154
Journal of extracellular vesicles 2025 Aug;14(8):e70154
Cascade Regulation of Blood Clot Stabilization-Cell Migration-Osteogenic Differentiation by Hollow Hydrogels for Periodontal Bone Regeneration and Repair.
Liu L, Wang Z, Sun Y, Liu Y, Li T, Zheng Q, Yang J, Dong H, Qi H, Xu Q
Advanced healthcare materials 2025 Aug;14(20):e2500614
Advanced healthcare materials 2025 Aug;14(20):e2500614
SERPINF1 knockdown attenuates chondrocyte senescence, hypertrophy, and inflammation in osteoarthritis to offer a potential therapeutic strategy.
Dong L, Yang Z, Liu J, Wu R, Liao Y, Kuang L
Cellular signalling 2025 Aug;132:111840
Cellular signalling 2025 Aug;132:111840
Pig Liver Esterase Hydrolysis of 2-Arachidonoglycerol Exacerbates PRRSV-Induced Inflammation via PI3K-Akt-NF-κB Pathway.
Fu Y, Zhu H, Xiao Q, Chen Q, Zhou Q, Wang X, Shi D
Cells 2025 Aug 8;14(16)
Cells 2025 Aug 8;14(16)
In situ-formed immunotherapeutic hydrogel containing sphingosine-1-phosphate for enhanced lung cancer immunotherapy.
Shen H, Deng Q, Chen Z, Zhang Q, Zhou X, Chen Q, Fan J
Science advances 2025 Aug 8;11(32):eadw5001
Science advances 2025 Aug 8;11(32):eadw5001
SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα.
Yao Y, Wang X, Xuan C, Li D, Huang W, Wei L, Ruan XZ, Li D, Chen Y
Aging and disease 2025 Aug 6;
Aging and disease 2025 Aug 6;
Solidago decurrens Lour. controls LPS-induced acute lung injury by reducing inflammatory responses and modulating the TLR4/NF-κB/NLRP3 signaling pathway.
Ma DY, Peng LF, Gao XY, Xing TJ, Hao ZH
Journal of ethnopharmacology 2025 Aug 29;352:120172
Journal of ethnopharmacology 2025 Aug 29;352:120172
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Cui Z, Gu G, Chen F, Li J, Du X, Chen S, Zhang H, Li C, Shao J, Xi J, Du Y, Zhao Q, Xi Y
Cell death & disease 2025 Aug 27;16(1):651
Cell death & disease 2025 Aug 27;16(1):651
Urate-lowering and renal-protective effects of sugarcane polyphenols in hyperuricemia: mechanisms and key components.
Li K, Han Y, Wang Y, Zhang C, Liu W, Xi Y, Zhou Y, Li L, Li H
Food & function 2025 Aug 26;16(17):6760-6772
Food & function 2025 Aug 26;16(17):6760-6772
β-Nicotinamide mononucleotide protects against hypervirulent Klebsiella pneumoniae bloodstream infection and liver injury.
Cao Z, Meng B, Chen J, Ge R, Liu Y, Li J
mSphere 2025 Aug 26;10(8):e0036125
mSphere 2025 Aug 26;10(8):e0036125
HMGB1/RAGE signaling mediates the activation of microglia and participates in depressive-like behaviors and cognitive deficits in rats after ischemia-reperfusion.
Fan L, Zhang X, Song X, Yang L, Liu H, Zhang Y, Li K, Jin X, Lei H, Zhang Z, Zhang F, Song J
Behavioural brain research 2025 Aug 24;492:115662
Behavioural brain research 2025 Aug 24;492:115662
CD24 recruits tumor-associated neutrophils to promote the progression of hepatocellular carcinoma.
Wang J, Li H, Liu Y, Xiao X, Li J, Jiang S, Wang J, Cheng Y, Song Z, Wu Y, Gu C, Chen S, Xiong J, Zhang H, Xiang Y, Liao X
Journal for immunotherapy of cancer 2025 Aug 21;13(8)
Journal for immunotherapy of cancer 2025 Aug 21;13(8)
Isorhamnetin protects against D-GalN/LPS-induced acute liver injury in mice through anti-oxidative stress, anti-inflammation, and anti-apoptosis.
Long L, Zhang M, Qin HZ, Xu LB, Wang BB, Wu WY, Zhu H, Lin S
BMC complementary medicine and therapies 2025 Aug 2;25(1):297
BMC complementary medicine and therapies 2025 Aug 2;25(1):297
TRIM31 triggers colorectal carcinogenesis and progression by maintaining YBX1 protein stability through ubiquitination modification.
Li X, Wu Y, Guo J, Huang P, Li Q, Gao Z, Hu Y, Gao A, Sun M, Min H, Zhou J
Cell death & disease 2025 Aug 16;16(1):621
Cell death & disease 2025 Aug 16;16(1):621
Iodoacetamide triggers ovarian dysfunction in mice through TGF-β signaling pathway and apoptosis.
Xiao C, Li Q, Li M, Han Y, Xu H, Jiang H, Zhang S, Jin Z, Gao L
Toxicology letters 2025 Apr;406:9-19
Toxicology letters 2025 Apr;406:9-19
Host factor Naf1 restricts HIV-1 infection of myeloid cells and compromises the capacity of dendritic cell to prime CD4(+) T cell.
Xie C, Jin X, Li WW, Wang JH
Virologica Sinica 2025 Apr;40(2):217-224
Virologica Sinica 2025 Apr;40(2):217-224
The chemokine receptor type 5 inhibitor maraviroc alleviates sepsis-associated liver injury by regulating MAPK/NF-κB signaling.
Shao J, Wang T, Tang C, Yu J, Chen Y, Guo X, Wang H, Zhou L, Zhang G, Li Y, Yu H, Zheng R
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):3655-3666
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):3655-3666
CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway.
Zhou X, Zhao X, Li Y, Zhang B
Molecular medicine reports 2025 Apr;31(4)
Molecular medicine reports 2025 Apr;31(4)
Crucial role of low molecular weight chondroitin sulfate from hybrid sturgeon cartilage in osteoarthritis improvement: Focusing on apoptosis, systemic inflammation, and intestinal flora.
Jing Y, Wang K, Pi T, Chen Z, Liu T, Liu X, Ye H, Xu X, Zhao Y
International journal of biological macromolecules 2025 Apr;298:139850
International journal of biological macromolecules 2025 Apr;298:139850
NLRC3 affects the development of psoriasis by modulating the NF-κB signaling pathway mediated inflammatory response through its interaction with TRAF6.
Zhang W, Zhu G, Sun H, Jiang C
Immunology letters 2025 Apr;272:106949
Immunology letters 2025 Apr;272:106949
Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway.
Li G, Guan Y, Xu L, Peng G, Han Q, Wang T, Xu Z, Wen X, Lou H, Shen T
Chinese journal of natural medicines 2025 Apr;23(4):421-430
Chinese journal of natural medicines 2025 Apr;23(4):421-430
RNF144A inhibits autophagy by targeting BECN1 for degradation during L. monocytogenes infection.
Yang B, Shen M, Lu C, Wang Y, Zhao X, Zhang Q, Qin X, Pei J, Wang H, Wang J
Autophagy 2025 Apr;21(4):789-806
Autophagy 2025 Apr;21(4):789-806
Neuroimmune regulation of IFITM3 via γ-secretase in astrocytes during cerebral ischemia-reperfusion.
Ni X, Pan Y, Liu X, Zhu Y, Yao X, Mo Y, Dai Q, Wang J
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167733
Biochimica et biophysica acta. Molecular basis of disease 2025 Apr;1871(4):167733
Sulfonation of Capsaicin by sulfotransferases produces an anti-inflammatory metabolite with NF-κB pathway modulatory activity.
Hu W, Wang H, Gan L, Lin Y, Fu Y, Tan W, Dou X, Ye L
Fitoterapia 2025 Apr;182:106463
Fitoterapia 2025 Apr;182:106463
Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway.
Mao Z, Lin X, Hu Y, Liu Y, Yu S, Zhou T, Zhang J, Yang X, Tian S, Miao M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156496
Dual role of Baimao-Longdan-Congrong-Fang in inhibiting Staphylococcus aureus virulence factors and regulating TNF-α/TNFR1/NF-κB/MMP9 axis.
Jiang T, Zhu X, Yin Z, Gao R, Li Y, Li C, Meng Q, Zhu X, Song W, Su X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156477
Sanzi Yangqin Decoction improved acute lung injury by regulating the TLR2-mediated NF-κB/NLRP3 signaling pathway and inhibiting the activation of NLRP3 inflammasome.
Gan A, Chen H, Lin F, Wang R, Wu B, Yan T, Jia Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156438
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156438
An Anti-CD147 Antibody-Drug Conjugate Mehozumab-DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey.
Huang W, Zhong L, Shi Y, Ma Q, Yang X, Zhang H, Zhang J, Wang L, Wang K, Li J, Zou J, Yang X, Yang L, Zeng Q, Jing L, Chen ZN, Zhao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410438
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2410438
Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.
Lei D, Liao L, Qin T, Guan X, Duan K, Gao Z, Jin W, Yin M, Zhang K, Liu Y, Chen Y, Gao H, Li J, Huang F, Liu W, Xia C, Wang B, Huang H, Lv S, Zhi Q, Huang J, Gao M, Lu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2413697
Shuxuetong injection inhibits pyroptosis in acute ischemic stroke via CD44/NLRP3/GSDMD signal.
Shang J, Huang G, Wang B, Wang J, Wei W, Cui Y, Liu X
Journal of ethnopharmacology 2025 Apr 9;345:119618
Journal of ethnopharmacology 2025 Apr 9;345:119618
Proteomic analysis reveals that Acalypha australis L. mitigates chronic colitis by modulating the FABP4/PPARγ/NF-κB signaling pathway.
Quan X, Miao Z, Han R, Deng R, Cao Y, Tian J, Lu Y, Wang G, Yu X, Wu Y, Dai C
Journal of ethnopharmacology 2025 Apr 9;345:119585
Journal of ethnopharmacology 2025 Apr 9;345:119585
Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis.
Xiang W, Zhu Z, Shang Q, Yasin P, Wu Y, Song X
Pharmaceutics 2025 Apr 8;17(4)
Pharmaceutics 2025 Apr 8;17(4)
The Role and Mechanism of TRIM13 Regulation of TRAF6 Ubiquitination in the Synergy of Inflammatory Responses and Neurotoxicity Induced by METH and HIV- 1 Tat Protein in Astrocytes.
Tan Y, Miao L, Wang C, Wang H, Li Y, Huang Y, Teng H, Tian Y, Yang G, Zeng X, Li J
Neurotoxicity research 2025 Apr 7;43(2):21
Neurotoxicity research 2025 Apr 7;43(2):21
Berberine Alleviates 1-Methyl-3-Nitro-1-Nitrosoguanidine- Induced Chronic Atrophic Gastritis in Rats.
Wang L, Xie L
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(11):723-731
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(11):723-731
Alleviation of obesity cardiomyopathy by Fisetin through the inhibition of NF-κB/MAPK signaling.
Liu X, Zhu J, Li C, Tong C, Zhao C, Lin X, Wang Y, Alinejad T, Wu H, Chen G, Li L
International immunopharmacology 2025 Apr 4;151:114319
International immunopharmacology 2025 Apr 4;151:114319
A Visible-Light Photocatalysis/Hydrolysis Hydrogen-Generating Nanoplatform for Dynamic Inflammation Management via Immune Metabolism Orchestration during Wound Repair.
Xu Z, Yang Y, Li X, Wang J, Chen S, An T, Hu C, Deng C, Zhou F, Xiang L, Qu Y, Man Y
ACS applied materials & interfaces 2025 Apr 30;17(17):24918-24939
ACS applied materials & interfaces 2025 Apr 30;17(17):24918-24939
Unveiling the multifaceted benefits of Simiao Pill in ulcerative colitis: Integrative analysis of signaling pathways, gut microbiota, and lipid metabolism.
Peng X, Zou Q, Yang C, Pu X, Yang H, Wang M, Chen S, Pu S, Chen X, He H, Li Y
Journal of ethnopharmacology 2025 Apr 25;346:119714
Journal of ethnopharmacology 2025 Apr 25;346:119714
Regulation of monocyte polarization through nuclear factor Kappa B /inhibitor of Kappa B Alpha pathway by Cuscuta chinensis Lam. In postmenopausal osteoporosis.
Li X, Wang Z, Chen Y, Yang Y, Shao H, Feng X, Ren Y
Journal of ethnopharmacology 2025 Apr 25;346:119710
Journal of ethnopharmacology 2025 Apr 25;346:119710
Bioinformatics analysis and experimental validation of potential targets and pathways in chronic kidney disease associated with renal fibrosis.
Huimin C, Yuxin Z, Peng W, Wei G, Hong L, Na L, Jianjun Y
Journal of translational medicine 2025 Apr 2;23(1):387
Journal of translational medicine 2025 Apr 2;23(1):387
Lactobacillus murinus ZNL-13 Modulates Intestinal Barrier Damage and Gut Microbiota in Cyclophosphamide-Induced Immunosuppressed Mice.
Dong Y, Zhang L, Qiu D, Yao R, Jia H, Wang H, Zhou L, Zhang J, Zhang N
Foods (Basel, Switzerland) 2025 Apr 19;14(8)
Foods (Basel, Switzerland) 2025 Apr 19;14(8)
Porcine reproductive and respiratory syndrome virus nsp5 inhibits the activation of the Nrf2/HO-1 pathway by targeting p62 to antagonize its antiviral activity.
Wang F, Amona FM, Pang Y, Zhang Q, Liang Y, Chen X, Ke Y, Chen J, Song C, Wang Y, Li Z, Zhang C, Fang X, Chen X
Journal of virology 2025 Apr 15;99(4):e0158524
Journal of virology 2025 Apr 15;99(4):e0158524
Anxiolytic effects of accelerated continuous theta burst stimulation on mice exposed to chronic restraint stress and the underlying mechanism involving gut microbiota.
Wang Y, Guo C, Zang B, Wang P, Yang C, Shi R, Kong Y, Sui A, Li S, Lin Y
Journal of affective disorders 2025 Apr 15;375:49-63
Journal of affective disorders 2025 Apr 15;375:49-63
Therapeutic potential of naturally derived carbon dots in sepsis-associated acute kidney injury.
Wang L, Li ZY, Zhong CL, Teng ZY, Wang B, Rehman A, Han LW, Zeng KW, Zhang JG, Lu ZY
Chinese medicine 2025 Apr 11;20(1):49
Chinese medicine 2025 Apr 11;20(1):49
Asparagine transporter supports macrophage inflammation via histone phosphorylation.
Wang C, Ye Y, Zhao M, Chen Q, Liu B, Ren W
Science advances 2025 Apr 11;11(15):eads3506
Science advances 2025 Apr 11;11(15):eads3506
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Zhang L, Feng L, Zhao Y, Geng Y, Liu R, Ma Y, Bo W, Xi Y, Tian Z
Life sciences 2025 Apr 1;366-367:123500
Life sciences 2025 Apr 1;366-367:123500
Exercise antagonizes cadmium-caused liver and intestinal injury in mice via Nrf2 and TLR2/NF-κB signalling pathway.
Zhang D, Liu J, Liu J, Fatima M, Yang L, Qin Y, Li W, Sun Z, Yang B
Ecotoxicology and environmental safety 2025 Apr 1;294:118100
Ecotoxicology and environmental safety 2025 Apr 1;294:118100
DNA Methylation Mediates the Transcription of STAT4 to Regulate KISS1 During Follicular Development.
Chen D, Fang M, Huang E, Quan H, Zhang L, He Y, Zhou X, Ma B, Yuan X, Li J
Cells 2025 Apr 1;14(7)
Cells 2025 Apr 1;14(7)
Prognostic Significance of Nuclear Factor Kappa B (p65) among Breast Cancer Patients in Cape Coast Teaching Hospital.
Barnes P, Mensah A, Derkyi-Kwarteng L, Adankwa E, Agbo E, Yahaya ES, Amoani B, Adjei G, Ka-Chungu SMA, Akakpo PK, Halm-Lai F, Dankwa K, Amoako-Sakyi D, Nuvor SV, Obiri-Yeboah D, Saahene RO
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2024;33(4):310-320
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2024;33(4):310-320
DNMT3A transcriptionally downregulated by KLF5 alleviates LPS-induced inflammatory response and promotes osteogenic differentiation in hPDLSCs.
Guo J, Jia H
Journal of applied oral science : revista FOB 2024;32:e20240268
Journal of applied oral science : revista FOB 2024;32:e20240268
Therapeutic potential of HUC-MSC-exos primed with IFN-γ against LPS-induced acute lung injury.
Wang C, Jiang C, Yang Y, Xi C, Yin Y, Wu H, Qian C
Iranian journal of basic medical sciences 2024;27(3):375-382
Iranian journal of basic medical sciences 2024;27(3):375-382
LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease.
Cheng W, Song Q, Zhou A, Lin L, Zhao Y, Duan J, Zhou Z, Peng Y, Liu C, Zeng Y, Chen P
Tobacco induced diseases 2024;22
Tobacco induced diseases 2024;22
The VP1 Protein of Porcine Teschovirus Inhibits the Innate Immune Response to Viral Infection by Blocking MDA5 Activation.
Li Y, Zhang X, Zhao B, Zhao C, Lei X, Huang H, Li C, Zheng M, Lan T, Sun W, Lu H
Transboundary and emerging diseases 2024;2024:6649669
Transboundary and emerging diseases 2024;2024:6649669
Identification of a Novel NLRP12 Frameshift Mutation (Val730Glyfs(∗)41) by Whole-Exome Sequencing in Patients with Crohn's Disease.
Chen J, Huang Y, Chen H, Yang Q, Zheng W, Lin Y, Xue M, Wang C
Human mutation 2024;2024:5573272
Human mutation 2024;2024:5573272
RETRACTED: Curcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway.
Ding D, Liu G, Yan J, Zhang Q, Meng F, Wang L
PloS one 2024;19(9):e0309807
PloS one 2024;19(9):e0309807
miR-328-3p targets TLR2 to ameliorate oxygen-glucose deprivation injury and neutrophil extracellular trap formation in HUVECs via inhibition of the NF-κB signaling pathway.
Yao M, Fang C, Wang Z, Guo T, Wu D, Ma J, Wu J, Mo J
PloS one 2024;19(2):e0299382
PloS one 2024;19(2):e0299382
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Lu L, Zhu C, Xu J, Hu Y, Dai J, Wang S, Wei T
International journal of chronic obstructive pulmonary disease 2024;19:957-967
International journal of chronic obstructive pulmonary disease 2024;19:957-967
Unexpected Inhibitory Role of Silica Nanoparticles on Lung Cancer Development by Promoting M1 Polarization of Macrophages.
Xiang M, Chen C, Chen Y, Zhang Y, Shi L, Chen Y, Li J, Li B, Zeng B, Xing HR, Wang J, Zou Z
International journal of nanomedicine 2024;19:11087-11104
International journal of nanomedicine 2024;19:11087-11104
Reduced Proliferative Capacity and Defense against Staphylococcus aureus in Human Nasal Mucosal Epithelium Lacking ZNF365.
Du X, Yu L, Wang L, Yan X, Xu B, Chai F, Li D, Zi J, Zhang J, Jiang Y
International archives of allergy and immunology 2024;185(5):466-479
International archives of allergy and immunology 2024;185(5):466-479
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Zhou Y, Xiong X, Cheng Z, Chen Z, Wu S, Yu Y, Liu Y, Chen G, Li L
Drug design, development and therapy 2024;18:4825-4838
Drug design, development and therapy 2024;18:4825-4838
Study on the Underlying Mechanism of Yinhua Gout Granules in the Treatment of Gouty Arthritis by Integrating Transcriptomics and Network Pharmacology.
Fan QQ, Zhai BT, Zhang D, Zhang XF, Cheng JX, Guo DY, Tian H
Drug design, development and therapy 2024;18:3089-3112
Drug design, development and therapy 2024;18:3089-3112
Xinfeng Capsule Inhibits Pyroptosis and Ameliorates Myocardial Injury in Rats with Adjuvant Arthritis via the GAS5/miR-21/TLR4 Axis.
Fu W, Cao Y, Liu J, Huang C, Shu K, Zhu N
Drug design, development and therapy 2024;18:2421-2433
Drug design, development and therapy 2024;18:2421-2433
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats.
Zhao YZ, Zhang XN, Yin Y, Xiao PL, Gao M, Zhang LM, Zhou SH, Yu SN, Wang XL, Zhao YS
International journal of ophthalmology 2024;17(2):228-238
International journal of ophthalmology 2024;17(2):228-238
Study on the Anti-Atherosclerotic Mechanisms of Xin-Tong-Tai Granule Through Network Pharmacology, Molecular Docking, and Experimental Validation.
Zhu J, Wang Z, Liu C, Shi M, Guo Z, Li Y, Yu R, Wei J
Journal of inflammation research 2024;17:8147-8164
Journal of inflammation research 2024;17:8147-8164
Tanshinone IIA Promoted Autophagy and Inhibited Inflammation to Alleviate Podocyte Injury in Diabetic Nephropathy.
Li Y, Wu T, Li H, Liu M, Xu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:2709-2724
Identification of Macrophage-Related Biomarkers for Abdominal Aortic Aneurysm Through Combined Single-Cell Sequencing and Machine Learning.
Yao G, Hu X, Song D, Yao J, Chen D, Luan T, Zhao Y
Journal of inflammation research 2024;17:11009-11027
Journal of inflammation research 2024;17:11009-11027
KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.
Chen Y, Wu X, Jiang Z, Li X
Frontiers in pharmacology 2024;15:1461931
Frontiers in pharmacology 2024;15:1461931
Ephedra sinica polysaccharide regulate the anti-inflammatory immunity of intestinal microecology and bacterial metabolites in rheumatoid arthritis.
Ma Y, Wei X, Peng J, Wei F, Wen Y, Liu M, Song B, Wang Y, Zhang Y, Peng T
Frontiers in pharmacology 2024;15:1414675
Frontiers in pharmacology 2024;15:1414675
Research on the metabolic regulation mechanism of Yangyin Qingfei decoction plus in severe pneumonia caused by Mycoplasma pneumoniae in mice.
Zhang T, Zhao X, Zhang X, Liang X, Guan Z, Wang G, Liu G, Wu Z
Frontiers in pharmacology 2024;15:1376812
Frontiers in pharmacology 2024;15:1376812
Material basis and molecular mechanisms of Chaihuang Qingyi Huoxue Granule in the treatment of acute pancreatitis based on network pharmacology and molecular docking-based strategy.
Yang J, Jiang YH, Zhou X, Yao JQ, Wang YY, Liu JQ, Zhang PC, Tang WF, Li Z
Frontiers in immunology 2024;15:1353695
Frontiers in immunology 2024;15:1353695
Shikonin Exerts an Antileukemia Effect against FLT3-ITD Mutated Acute Myeloid Leukemia Cells via Targeting FLT3 and Its Downstream Pathways.
Zhao MN, Su L, Song F, Wei ZF, Qin TX, Zhang YW, Li W, Gao SJ
Acta haematologica 2024;147(3):310-324
Acta haematologica 2024;147(3):310-324
Integrating machine learning algorithms and single-cell analysis to identify gut microbiota-related macrophage biomarkers in atherosclerotic plaques.
Ke Y, Yue J, He J, Liu G
Frontiers in cellular and infection microbiology 2024;14:1395716
Frontiers in cellular and infection microbiology 2024;14:1395716
Inhibitory effect of hydroxychloroquine on glucocorticoid-induced osteoporosis in lupus therapy.
Qiu W, Han X, Yu T, Jiang L, Wang X, Feng R, Duan X, Teng Y, Yin H, Bokarewa MI, Deng GM
Clinical & translational immunology 2024;13(10):e70010
Clinical & translational immunology 2024;13(10):e70010
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
Yu J, Meng Z, Liu X, Zheng Y, Xue D, Hao C, Wang L
ImmunoTargets and therapy 2024;13:789-803
ImmunoTargets and therapy 2024;13:789-803
Overexpression of the Mas1 gene mitigated LPS-induced inflammatory injury in mammary epithelial cells by inhibiting the NF-κB/MAPKs signaling pathways.
Yan S, Ju X, Lao J, Wen Z, Yong Y, Li Y, Li Y
Frontiers in veterinary science 2024;11:1446366
Frontiers in veterinary science 2024;11:1446366
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples.
Guerrero-Alba A, Bansal S, Sankpal AN, Mitra G, Rahman M, Ravichandran R, Poulson C, Fleming TP, Smith MA, Bremner RM, Mohanakumar T, Sankpal NV
Frontiers in molecular biosciences 2024;11:1365783
Frontiers in molecular biosciences 2024;11:1365783
Reprogramming exosomes for immunity-remodeled photodynamic therapy against non-small cell lung cancer.
Guo J, Zhao W, Xiao X, Liu S, Liu L, Zhang L, Li L, Li Z, Li Z, Xu M, Peng Q, Wang J, Wei Y, Jiang N
Bioactive materials 2024 Sep;39:206-223
Bioactive materials 2024 Sep;39:206-223
Prunus persica (L.) Batsch blossom soluble dietary fiber synergia polyphenol improving loperamide-induced constipation in mice via regulating stem cell factor/C-kit, NF-κB signaling pathway and gut microbiota.
Liang S, He Z, Liang Z, Wang K, Du B, Guo R, Li P
Food research international (Ottawa, Ont.) 2024 Sep;192:114761
Food research international (Ottawa, Ont.) 2024 Sep;192:114761
Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned piglets.
Zheng X, Wang Y, Zhou X, Deng T, Zhao Y, Fu Z, Wei Y, Ma W, Zhang S, Guan W, Chen F
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Sep;18:419-432
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Sep;18:419-432
Rice bran active peptide (RBAP) inhibited macrophage differentiation to foam cell and atherosclerosis in mice via regulating cholesterol efflux.
Mu J, Lin Q, Chen Y, Wang J, Yu X, Huang F, Liu X, Fang Y, Li Y, Zhu B, Liang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155864
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155864
Polygala tenuifolia willd. Extract alleviates LPS-induced acute lung injury in rats via TLR4/NF-κB pathway and NLRP3 inflammasome suppression.
Guo S, Zhang J, Zhang Q, Xu S, Liu Y, Ma S, Hu X, Liu Y, Zhang X, Jiang R, Zhang Z, Zhang Z, Zhou Z, Wen L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155859
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155859
Catalpol alleviates heat stroke-induced liver injury in mice by downregulating the JAK/STAT signaling pathway.
Ji XY, Feng JT, Zhou ZY, Zhang YY, Ma SZ, Wang XQ, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155853
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155853
Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.
Zhao L, Zhao C, Miao Y, Lei S, Li Y, Gong J, Peng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155852
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155852
The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress.
Ma Y, Guo J, Rao H, Xin J, Song X, Liu R, Shao S, Hou J, Kong L, Hu Z, He L, Pan F, Guo Z
Journal of extracellular vesicles 2024 Sep;13(9):e12505
Journal of extracellular vesicles 2024 Sep;13(9):e12505
The role of α7nAchR and PD-L1 in neuroimmune regulation of keloid treatment.
Luo Z, Zheng S, Liu J, Qi F
Cellular signalling 2024 Sep;121:111275
Cellular signalling 2024 Sep;121:111275
Fatty acids promote M1 polarization of monocyte-derived macrophages in healthy or ketotic dairy cows and a bovine macrophage cell line by impairing mTOR-mediated autophagy.
Sun X, Gao S, Chang R, Jia H, Xu Q, Mauck J, Loor JJ, Li X, Xu C
Journal of dairy science 2024 Sep;107(9):7423-7434
Journal of dairy science 2024 Sep;107(9):7423-7434
Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome.
Wang Y, Zhang W, Yang Y, Qin J, Wang R, Wang S, Fu W, Niu Q, Wang Y, Li C, Li H, Zhou Y, Liu M
Bone research 2024 Sep 6;12(1):53
Bone research 2024 Sep 6;12(1):53
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Mou L, Sun D, Qu J, Tan X, Wang S, Zeng Q, Liu C
Journal of hazardous materials 2024 Sep 5;476:135101
Journal of hazardous materials 2024 Sep 5;476:135101
Palmatine ameliorates N-methyl-N'-nitrosoguanidine-induced chronic atrophic gastritis through the STAT1/CXCL10 axis.
Zhou Y, Wang Q, Tang W, Ma Z, Yang Z, Li X, Chen W, Ma H, Ye X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70037
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 30;38(18):e70037
MLN4924 alleviates autoimmune myocarditis by promoting Act1 degradation and blocking Act1-mediated mRNA stability.
Jiang Z, Li Z, Chen Y, Nie N, Liu X, Liu J, Shen Y
International immunopharmacology 2024 Sep 30;139:112716
International immunopharmacology 2024 Sep 30;139:112716
β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment.
Zou C, Cai R, Li Y, Xue Y, Zhang G, Alitongbieke G, Pan Y, Zhang S
iScience 2024 Sep 20;27(9):110766
iScience 2024 Sep 20;27(9):110766
Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.
Wang Y, Zhang J, Yang Z, Li C, Zhang C, Sun S, Jiao Z, Che G, Gao H, Liu J, Li J
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20496-20512
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20496-20512
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Yang S, Sun X, Liu D, Zhang Y, Gao X, He J, Cui M, Fu S, He D
Food & function 2024 Sep 16;15(18):9390-9408
Food & function 2024 Sep 16;15(18):9390-9408
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Yan X, Bai X, Fu R, Duan Z, Zeng W, Zhu C
Food & function 2024 Sep 16;15(18):9037-9052
Food & function 2024 Sep 16;15(18):9037-9052
Inhibiting Soluble Epoxide Hydrolase Suppresses NF-κB p65 Signaling and Reduces CXCL10 Expression as a Potential Therapeutic Target in Hashimoto's Thyroiditis.
Feng J, Xu X, Cai W, Yang X, Niu R, Han Z, Tian L
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
The Journal of clinical endocrinology and metabolism 2024 Sep 16;109(10):2579-2588
FABP4 deficiency ameliorates alcoholic steatohepatitis in mice via inhibition of p53 signaling pathway.
Xing H, Wu Z, Jiang K, Yuan G, Guo Z, Yu S, He S, Zhong F
Scientific reports 2024 Sep 10;14(1):21135
Scientific reports 2024 Sep 10;14(1):21135
Hydrogen combined with tetrandrine attenuates silica-induced pulmonary fibrosis via suppressing NF-kappaB/NLRP3 signaling pathway-mediated epithelial mesenchymal transition and inflammation.
Li J, Cui P, Jing H, Chen S, Ma L, Zhang W, Wang T, Ma J, Cao M, Yang Y, Bai J, Shao H, Du Z
International immunopharmacology 2024 Sep 10;138:112563
International immunopharmacology 2024 Sep 10;138:112563
Identification of novel biomarker hsa_circ_0003914 for rheumatoid arthritis from plasma exosomes.
He Q, Sha X, Ji J, Liu W, Sun C, Gu Z
International immunopharmacology 2024 Sep 10;138:112562
International immunopharmacology 2024 Sep 10;138:112562
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Zhang X, Hu F, Li J, Chen L, Mao YF, Li QB, Nie CY, Lin C, Xiao J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
Dietary Zn proteinate with moderate chelation strength alleviates heat stress-induced intestinal barrier function damage by promoting expression of tight junction proteins via the A20/NF-κB p65/MMP-2 pathway in the jejunum of broilers.
Hu Y, Zhang W, Yang K, Lin X, Liu HC, Odle J, See MT, Cui X, Li T, Wang S, Liao X, Zhang L, Li S, Hu Y, Luo X
Journal of animal science and biotechnology 2024 Sep 1;15(1):115
Journal of animal science and biotechnology 2024 Sep 1;15(1):115
Role of NF-κB signaling pathway in H(2)O(2)-induced oxidative stress of hiPSCs.
Qin J, Yang J, Li J, Zhao D, An J, Zhai Z, Wang H, Li J, Dou M, Du R
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1021-1033
In vitro cellular & developmental biology. Animal 2024 Oct;60(9):1021-1033
Hypoxic microenvironment promotes diabetic wound healing by polarizing macrophages to the M2 phenotype in vivo.
Cai F, Wang P, Yuan M, Chen W, Liu Y
Journal of molecular histology 2024 Oct;55(5):967-976
Journal of molecular histology 2024 Oct;55(5):967-976
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
Kong L, Liang Y, Hou J, Zhang W, Jiang S
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
EtROP38 suppresses apoptosis of host cells infected with Eimeria tenella by inhibition of the p38MAPK pathway.
Duan BT, Zhang HY, Song ZH, Han XY, Cui KL, Xu T, Zhang Y, Zhao YJ, Lei X, Tan F, Guo LL, Yang HL, Zhang L, Bai R, Lv XL, Zheng MX
Veterinary parasitology 2024 Oct;331:110296
Veterinary parasitology 2024 Oct;331:110296
2,5-Dihydroxyacetophenone attenuates acute kidney injury induced by intra-abdominal infection in rats.
Han T, Jiang Y, Ge W, Lu Y, Liu R, Sun Z
Nephrology (Carlton, Vic.) 2024 Oct;29(10):636-644
Nephrology (Carlton, Vic.) 2024 Oct;29(10):636-644
Structure characterization and immunological activity of capsular polysaccharide from live and heat-killed Lacticaseibacillus paracasei 6235.
Wang Y, Liu R, Xie Z, Du L, Wang Y, Han J, Zhang L
International journal of biological macromolecules 2024 Oct;277(Pt 1):134010
International journal of biological macromolecules 2024 Oct;277(Pt 1):134010
A preliminary study of T-2 toxin that cause liver injury in rats via the NF-kB and NLRP3-mediated pyroptosis pathway.
Zheng S, Li H, Dong H, Qi F, Zhang B, Yu Q, Lin B, Jiang H, Du H, Liu Y, Yu J
Toxicon : official journal of the International Society on Toxinology 2024 Oct;249:108060
Toxicon : official journal of the International Society on Toxinology 2024 Oct;249:108060
A novel HOIP frameshift variant alleviates NF-kappaB signalling and sensitizes cells to TNF-induced death.
Wang M, Bai Y, Jiang D, Wang Y, Zhao F, Zhou Y, Zhou M, Chen Y, Yu C, Wang X, Guo Q, Zha L, Li Q, Cao Z, Wu J, Shi S, Wang Q, Xu C, Kong X, Tu X
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167355
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167355
Lipocalin-2-mediated intestinal epithelial cells pyroptosis via NF-κB/NLRP3/GSDMD signaling axis adversely affects inflammation in colitis.
Yang Y, Li S, Liu K, Zhang Y, Zhu F, Ben T, Chen Z, Zhi F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167279
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167279
Schisandra chinensis lignans regulate and cooperate with endogenous cannabinoid systems to ameliorate intestinal barrier injury associated with depression.
Wang J, Zheng A, Lin F, Zhang X, Shi K, Yan T, Jia Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155929
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155929
Proteomics reveals the pharmacological mechanism of flavonoids from Astragali Complanati Semen in preventing chronic liver injury.
Chen L, Kong X, Zhou R, Hu J, Zhou R, Song Z, Tang Z, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155910
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155910
Pathogen-Mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Immunization.
Wan H, Deng K, Huang Z, Yang Y, Jing B, Feng Y, Li Y, Liu Y, Lu M, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401120
Advanced healthcare materials 2024 Oct;13(26):e2401120
Dehydrocostus Lactone Ameliorates LPS-Induced Acute Lung Injury by Inhibiting PFKFB3-Mediated Glycolysis.
Li Y, Wang X, Zhao L, Pan B, Xu X, Zhu D
Journal of cellular biochemistry 2024 Oct;125(10):e30639
Journal of cellular biochemistry 2024 Oct;125(10):e30639
Sirtuin 5-Mediated Desuccinylation of ALDH2 Alleviates Mitochondrial Oxidative Stress Following Acetaminophen-Induced Acute Liver Injury.
Yu Q, Zhang J, Li J, Song Y, Pan J, Mei C, Cui M, He Q, Wang H, Li H, Cheng B, Zhang Y, Guo W, Zhu C, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2402710
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2402710
WNT2B high‑expressed fibroblasts induce the fibrosis of IBD by promoting NK cells secreting IL-33.
Cheng Y, Xiao S, Lan L, Liu D, Tang R, Gu J, Ma L, He Z, Chen X, Geng L, Chen P, Li H, Ren L, Zhu Y, Cheng Y, Gong S
Journal of molecular medicine (Berlin, Germany) 2024 Oct;102(10):1199-1215
Journal of molecular medicine (Berlin, Germany) 2024 Oct;102(10):1199-1215
Orally Administered Ginkgolide C Alleviates MPTP-Induced Neurodegeneration by Suppressing Neuroinflammation and Oxidative Stress through Microbiota-Gut-Brain Axis in Mice.
Gao X, Fu S, Wen J, Yan A, Yang S, Zhang Y, Liu D, He D
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22115-22131
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22115-22131
STING Agonist Delivered by Neutrophil Membrane-Coated Gold Nanoparticles Exerts Synergistic Tumor Inhibition with Radiotherapy.
Lu D, Li W, Tan J, Li Y, Mao W, Zheng Y, Yang M, Wang J, Wang W, Wang S, Gao J, Liu Y
ACS applied materials & interfaces 2024 Oct 9;16(40):53474-53488
ACS applied materials & interfaces 2024 Oct 9;16(40):53474-53488
Transcriptomic analysis reveals the critical role of chemokine signaling in the anti-atherosclerosis effect of Xuefu Zhuyu decoction.
Jia D, Zhao M, Zhang X, Cheng X, Wei Q, Lou L, Zhao Y, Jin Q, Chen M, Zhang D
Journal of ethnopharmacology 2024 Oct 5;332:118245
Journal of ethnopharmacology 2024 Oct 5;332:118245
Isomalto-Oligosaccharide Potentiates Alleviating Effects of Intermittent Fasting on Obesity-Related Cognitive Impairment during Weight Loss and the Rebound Weight Gain.
Liu T, Zhou L, Dong R, Qu Y, Liu Y, Song W, Lv J, Wu S, Peng W, Shi L
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23875-23892
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23875-23892
Upregulation of Cullin1 neddylation promotes glycolysis and M1 polarization of macrophage via NF-κB p65 pathway in sepsis.
Qin F, Tan H, Yang Y, Xu L, Yang X
Functional & integrative genomics 2024 Oct 30;24(6):204
Functional & integrative genomics 2024 Oct 30;24(6):204
Schisandrin B restores M1/M2 balance through miR-124 in lipopolysaccharide-induced BV2 cells.
Yang Y, Liu R, Sun Y, Wu B, He B, Jia Y, Yan T
The Journal of pharmacy and pharmacology 2024 Oct 3;76(10):1352-1361
The Journal of pharmacy and pharmacology 2024 Oct 3;76(10):1352-1361
Mutation of Pseudomonas aeruginosa lasI/rhlI diminishes its cytotoxicity, oxidative stress, inflammation, and apoptosis on THP-1 macrophages.
Ren Y, You X, Zhu R, Li D, Wang C, He Z, Hu Y, Li Y, Liu X, Li Y
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Microbiology spectrum 2024 Oct 3;12(10):e0414623
Sequential system based on ferritin delivery system and cell therapy for modulating the pathological microenvironment and promoting recovery.
Xu L, Yang J, Cao X, Chen J, Liu Z, Cai L, Yu Y, Huang H
International journal of pharmaceutics 2024 Oct 25;664:124607
International journal of pharmaceutics 2024 Oct 25;664:124607
ACOD1 mediates Staphylococcus aureus-induced inflammatory response via the TLR4/NF-κB signaling pathway.
Dai F, Zhang X, Ma G, Li W
International immunopharmacology 2024 Oct 25;140:112924
International immunopharmacology 2024 Oct 25;140:112924
MRG15 aggravates sepsis-related liver injury by promoting PCSK9 synthesis and secretion.
Gu B, Jiang Y, Huang Z, Li H, Yu W, Li T, Liu C, Wang P, Chen J, Sun L, Tan P, Fu W, Wen J
International immunopharmacology 2024 Oct 25;140:112898
International immunopharmacology 2024 Oct 25;140:112898
Bifidobacterium lactis-Derived Vesicles Attenuate Hippocampal Neuroinflammation by Targeting IL-33 to Regulate FoxO6/P53 Signaling.
Du X, Zhang M, Wang R, Zeng Z, Zhao W, Fang B, Lan H, Hung W, Gao H
Nutrients 2024 Oct 22;16(21)
Nutrients 2024 Oct 22;16(21)
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Scientific reports 2024 Oct 21;14(1):24787
Scientific reports 2024 Oct 21;14(1):24787
The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals.
Li N, Yun B, Zeng L, Lv Y, Zhou Y, Fang M, Li S, Chen Y, Huang E, Zhang L, Jiang Y, Zhang H, Li J, Yuan X
Communications biology 2024 Oct 2;7(1):1246
Communications biology 2024 Oct 2;7(1):1246
Effects of Nitric Oxide on Bladder Detrusor Overactivity through the NRF2 and HIF-1α Pathways: A Rat Model Induced by Metabolic Syndrome and Ovarian Hormone Deficiency.
Lin HY, Lu JH, Lin RJ, Chueh KS, Juan TJ, Mao JW, Lee YC, Chuang SM, Shen MC, Sun TW, Juan YS
International journal of molecular sciences 2024 Oct 16;25(20)
International journal of molecular sciences 2024 Oct 16;25(20)
Exosomal let-7b-5p deriving from parietal epithelial cells attenuate renal fibrosis through suppression of TGFβR1 and ARID3a in obstructive kidney disease.
Song A, Wang M, Xie K, Lu J, Zhao B, Wu W, Qian C, Hong W, Gu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 15;38(19):e70085
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Oct 15;38(19):e70085
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Ali M, Ullah H, Farooqui NA, Deng T, Siddiqui NZ, Ilyas M, Ali S, Rahman MU, Rehman AU, Alioui Y, Wang L, Yi X
Heliyon 2024 Oct 15;10(19):e38370
Heliyon 2024 Oct 15;10(19):e38370
Chronic exposure to polystyrene microplastics induced LHR reduction and decreased testosterone levels through NF-κB pathway.
Jin H, Ding J, Liu H, Yang L, Li D, Han X
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
Environmental pollution (Barking, Essex : 1987) 2024 Oct 1;358:124543
Tas2R143 regulates the expression of the Blood-Testis Barrier tight junction protein in TM4 cells through the NF-κB signaling pathway.
Wang X, Wang JD, Li X, Wang T, Yao J, Deng R, Ma W, Liu S, Zhu Z
Theriogenology 2024 Oct 1;227:120-127
Theriogenology 2024 Oct 1;227:120-127
Sulforaphane Improves Liver Metabolism and Gut Microbiota in Circadian Rhythm Disorder Mice Models Fed With High-Fat Diets.
He C, Chen M, Jiang X, Ren J, Ganapathiraju SV, Lei P, Yang H, Pannu PR, Zhao Y, Zhang X
Molecular nutrition & food research 2024 Nov;68(21):e2400535
Molecular nutrition & food research 2024 Nov;68(21):e2400535
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis.
Chen L, Liu C, Xiang X, Qiu W, Guo K
International journal of molecular medicine 2024 Nov;54(5)
International journal of molecular medicine 2024 Nov;54(5)
Placental ischemia-upregulated angiotensin II type 1 receptor in hypothalamic paraventricular nucleus contributes to hypertension in rat.
Issotina Zibrila A, Zhou J, Wang X, Zeng M, Ali MA, Liu X, Alkuhali AA, Zeng Z, Meng Y, Wang Z, Li X, Liu J
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1677-1691
Pflugers Archiv : European journal of physiology 2024 Nov;476(11):1677-1691
Effects of daphnetin on the mechanism of epithelial-mesenchymal transition induced by HMGB1 in human lung adenocarcinoma cells (A549 cell line).
Gong SQ, Liu H, Wu JL, Xu JX
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1489-1510
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1489-1510
The role of phlorizin liposome-embedded oxidized sodium alginate/carboxymethyl chitosan in diabetic wound healing.
Wu X, Ding C, Liu X, Ding Q, Zhang S, Wang Y, Xin C, Wei H, Mao R, Zhang G, Zhao T, Liu W
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
International journal of biological macromolecules 2024 Nov;279(Pt 3):135324
USP9X-enriched MSC-sEV inhibits LSEC angiogenesis in MASH mice by downregulating the IκBα/NF-κB/Ang-2 pathway.
Wang Y, Wang C, Yang F, Chen Y, Shi Y, Xu R, Zhang Z, Yan Y
Pharmacological research 2024 Nov;209:107471
Pharmacological research 2024 Nov;209:107471
Increased adrenal steroidogenesis and suppressed corticosteroid responsiveness in critical COVID-19.
Wen TZ, Li TR, Chen XY, Chen HY, Wang S, Fu WJ, Xiao SQ, Luo J, Tang R, Ji JL, Huang JF, He ZC, Luo T, Zhao HL, Chen C, Miao JY, Niu Q, Wang Y, Bian XW, Yao XH
Metabolism: clinical and experimental 2024 Nov;160:155980
Metabolism: clinical and experimental 2024 Nov;160:155980
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Feng YL, Xu XR, Zhu QM, Chang J, Zhang HL, Wang N, Sun JB, Liu J, Zhang J, Sun CP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Ginsenoside Rk3 Treats Corneal Injury Through the HMGB1/TLR4/NF-κB Pathway.
Qu L, Huang Y, Wu Y, He L, Liu Y, Chen Z, Ma X, Fan D
Journal of agricultural and food chemistry 2024 Nov 6;72(44):24387-24399
Journal of agricultural and food chemistry 2024 Nov 6;72(44):24387-24399
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Li X, Sun H, Zhang L, Liang H, Zhang B, Yang J, Peng X, Sun J, Zhou Y, Zhai M, Jiang L, Zhu H, Duan W
European journal of pharmacology 2024 Nov 5;982:176894
European journal of pharmacology 2024 Nov 5;982:176894
The methyltransferase METTL3 regulates endothelial cell proliferation and inflammation via m(6)A RNA methylation-mediated TRAF1 expression.
Chen D, Xu W, Zheng H, Zhang Y, Lin Y, Han Y, Yao F, Shen H
Biochemical and biophysical research communications 2024 Nov 5;732:150399
Biochemical and biophysical research communications 2024 Nov 5;732:150399
Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein.
Han Q, Zhao H, Chen M, Xue W, Li J, Sun L, Shang Y
Communications biology 2024 Nov 5;7(1):1438
Communications biology 2024 Nov 5;7(1):1438
LncRNA DDX11-AS1 promotes breast cancer progression by targeting the miR-30c-5p/MTDH axis.
Li Y, Zhou M, Yang L, Liu S, Yang L, Xu B, Li X, Zhao H, Song Z
Scientific reports 2024 Nov 5;14(1):26745
Scientific reports 2024 Nov 5;14(1):26745
The Effect of Meloxicam on Inflammatory Response and Oxidative Stress Induced by Klebsiella pneumoniae in Bovine Mammary Epithelial Cells.
Liu K, Qiu S, Fang L, Cui L, Dong J, Guo L, Meng X, Li J, Wang H
Veterinary sciences 2024 Nov 29;11(12)
Veterinary sciences 2024 Nov 29;11(12)
Berbamine Promotes the Repair of Lower Limb Muscle Damage in Chronic Limb-Threatening Ischemia by Inhibiting Local Inflammation and NF-κB Nuclear Translocation.
Zheng L, Zhao B, Zhang Z, Liu Y, Zhang Y, Cai J, Qiao T
Pharmaceuticals (Basel, Switzerland) 2024 Nov 25;17(12)
Pharmaceuticals (Basel, Switzerland) 2024 Nov 25;17(12)
Effect of Tricin on cardiomyocyte damage caused by diabetic cardiomyopathy (DCM).
Yu R, Zhang Y, Wang T, Duan J, Li X
BMC cardiovascular disorders 2024 Nov 23;24(1):668
BMC cardiovascular disorders 2024 Nov 23;24(1):668
Probiotics alleviate chronic ethanol exposure-induced anxiety-like behavior and hippocampal neuroinflammation in male mice through gut microbiota-derived extracellular vesicles.
Pei J, Zhang C, Zhang Q, Yu H, Yuan H, Guo Y, Shen H, Liu H, Wang C, Meng F, Yu C, Tie J, Chen X, Wu X, Zhang G, Wang X
Journal of nanobiotechnology 2024 Nov 22;22(1):730
Journal of nanobiotechnology 2024 Nov 22;22(1):730
miRNA-431-5p enriched in EVs derived from IFN-β stimulated MSCs potently inhibited ZIKV through CD95 downregulation.
Yuan M, Tian X, Ma W, Zhang R, Zou X, Jin Y, Zheng N, Wu Z, Wang Y
Stem cell research & therapy 2024 Nov 19;15(1):435
Stem cell research & therapy 2024 Nov 19;15(1):435
LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.
Lin S, Ren Z, Li L, Xia S, Yang R, Ye H
Scientific reports 2024 Nov 19;14(1):28578
Scientific reports 2024 Nov 19;14(1):28578
YAP1 Inhibition Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer.
Song H, Lu T, Han D, Zhang J, Gan L, Xu C, Liu S, Li P, Zhang K, Hu Z, Li H, Li Y, Zhao X, Zhang J, Xing N, Shi C, Wen W, Yang F, Qin W
Cancer research 2024 Nov 15;84(22):3728-3742
Cancer research 2024 Nov 15;84(22):3728-3742
Vitamin C ameliorates D-galactose-induced senescence in HEI-OC1 cells by inhibiting the ROS/NF-κB pathway.
Xu B, Wang G, Xu L, Ding L, Li S, Han Y
Molecular biology reports 2024 Nov 15;51(1):1157
Molecular biology reports 2024 Nov 15;51(1):1157
Hippocampal cannabinoid type 2 receptor alleviates chronic neuropathic pain-induced cognitive impairment via microglial DUSP6 pathway in rats.
Xu L, Zhu A, Xu S, Zhao J, Song S, Zhu H, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Nov 15;38(21):e70152
The protective role of Cordyceps cicadae and its active ingredient myriocin against sodium iodate-induced age-related macular degeneration via an anti-necroptotic TNF-RIPK1/3 pathway.
Ma SZ, Dong S, Zhou ZY, Ji XY, Zhang YY, Wang XQ, Zhang B
Journal of ethnopharmacology 2024 Nov 15;334:118565
Journal of ethnopharmacology 2024 Nov 15;334:118565
Distinct pathways utilized by METTL3 to regulate antiviral innate immune response.
Hao H, Zhang F, Chen Z, Tan Z, Zhang H, Feng X, Zhang X, Deng T, Zhan G, Luo T, Zhang K, Ding S, Liu H, Zheng Z, Wang Y, Huang F, Guan W
iScience 2024 Nov 15;27(11):111071
iScience 2024 Nov 15;27(11):111071
Overcoming tyrosine kinase inhibitor resistance in lung cancer brain metastasis with CTLA4 blockade.
Fu M, Zhao J, Zhang L, Sheng Z, Li X, Qiu F, Feng Y, You M, Xu H, Zhang J, Zeng R, Huang Y, Li C, Chen W, Chen Z, Peng H, Li L, Wu Y, Ye D, Chi Y, Hua W, Mao Y
Cancer cell 2024 Nov 11;42(11):1882-1897.e7
Cancer cell 2024 Nov 11;42(11):1882-1897.e7
PFOS impairs cardiac function and energy metabolism under high-fat diet: Insights into role of circulating macrophage emphasized by exposure distribution.
Zhang Z, Yin H, Zheng C, Yu Z, Ahmed RZ, Niu Y, Zhou C, Ding J, Lin H, Lin Y, Zheng Y, Jin X
The Science of the total environment 2024 Nov 1;949:175139
The Science of the total environment 2024 Nov 1;949:175139
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Zeng L, Wang Y, Shen J, Wei X, Wu Y, Chi X, Zheng X, Yu X, Shi Y, Liu W
Experimental cell research 2024 Nov 1;443(1):114287
Experimental cell research 2024 Nov 1;443(1):114287
Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice.
Liu Y, Meng X, Tang C, Zheng L, Tao K, Guo W
Physiology & behavior 2024 Nov 1;286:114676
Physiology & behavior 2024 Nov 1;286:114676
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury.
Cao J, Yu X, Liu J, Fu J, Wang B, Wu C, Zhang S, Chen H, Wang Z, Xu Y, Sui T, Chang J, Cao X
Neural regeneration research 2024 Nov 1;19(11):2499-2512
Neural regeneration research 2024 Nov 1;19(11):2499-2512
IL1RAP Exacerbates Sepsis-Induced Pulmonary and Spleen Injury Through Regulating CD4(+) T Lymphocyte Differentiation.
Huang L, Wu C, Xu D, Cui Y, Tang J
Immunological investigations 2024 May;53(4):574-585
Immunological investigations 2024 May;53(4):574-585
iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation.
Zhang Y, Shi Q, Wang P, Huang C, Tang S, Zhou M, Hu Q, Wu L, Liang D
MedComm 2024 May;5(5):e553
MedComm 2024 May;5(5):e553
Administration of USP7 inhibitor p22077 alleviates Angiotensin II (Ang II)-induced atrial fibrillation in Mice.
Wang Y, Gu YH, Ren KW, Xie X, Wang SH, Zhu XX, Wang L, Yang XL, Bi HL
Hypertension research : official journal of the Japanese Society of Hypertension 2024 May;47(5):1309-1322
Hypertension research : official journal of the Japanese Society of Hypertension 2024 May;47(5):1309-1322
Curcumin attenuates aflatoxin B1-induced ileum injury in ducks by inhibiting NLRP3 inflammasome and regulating TLR4/NF-κB signaling pathway.
Pan H, Hu T, He Y, Zhong G, Wu S, Jiang X, Rao G, You Y, Ruan Z, Tang Z, Hu L
Mycotoxin research 2024 May;40(2):255-268
Mycotoxin research 2024 May;40(2):255-268
Retinoblastoma-associated protein is important for TRIM24-mediated activation of the mTOR signaling pathway through DUSP2 action in prostate cancer.
Ren D, Li W, Zeng R, Liu X, Liang H, Xiong W, Yang C, Jin X
Cell death and differentiation 2024 May;31(5):592-604
Cell death and differentiation 2024 May;31(5):592-604
Arylacryl amides: Design, synthesis and the protection against cisplatin-induced acute kidney injury via TLR4/STING/NF-κB pathway.
Wu X, Zhou L, Li Z, Rong K, Gao S, Chen Y, Zuo J, Tang W
Bioorganic chemistry 2024 May;146:107303
Bioorganic chemistry 2024 May;146:107303
Protective effects of sodium humate and its zinc and selenium chelate on the oxidative stress, inflammatory, and intestinal barrier damage of Salmonella Typhimurium-challenged broiler chickens.
Fan Y, Zhou W, Li G, Liu X, Zhong P, Liu K, Liu Y, Wang D
Poultry science 2024 May;103(5):103541
Poultry science 2024 May;103(5):103541
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
Song XQ, Guo X, Ding YX, Han YX, You ZH, Song Y, Yuan Y, Li L
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
The haemagglutinin-neuraminidase protein of velogenic Newcastle disease virus enhances viral infection through NF-κB-mediated programmed cell death.
Lu X, Zhan T, Zhou Q, Yang W, Liu K, Chen Y, Gao R, Hu J, Gu M, Hu S, Jiao XA, Wang X, Liu X, Liu X
Veterinary research 2024 May 7;55(1):58
Veterinary research 2024 May 7;55(1):58
Dietary Fiber-Derived Butyrate Alleviates Piglet Weaning Stress by Modulating the TLR4/MyD88/NF-κB Pathway.
Huangfu W, Ma J, Zhang Y, Liu M, Liu B, Zhao J, Wang Z, Shi Y
Nutrients 2024 May 30;16(11)
Nutrients 2024 May 30;16(11)
Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis.
Lu C, Deng S, Liu Y, Yang S, Qin D, Zhang L, Wang RR, Zhang Y
International immunopharmacology 2024 May 30;133:112038
International immunopharmacology 2024 May 30;133:112038
HuR promotes triglyceride synthesis and intestinal fat absorption.
Liu C, Lin Y, Wang Y, Lin S, Zhou J, Tang H, Yi X, Ma Z, Xia T, Jiang B, Tian F, Ju Z, Liu B, Gu X, Yang Z, Wang W
Cell reports 2024 May 28;43(5):114238
Cell reports 2024 May 28;43(5):114238
Readily Available Oral Prebiotic Protein Reactive Oxygen Species Nanoscavengers for Synergistic Therapy of Inflammation and Fibrosis in Inflammatory Bowel Disease.
Yu Y, Yang D, Lin B, Zhu L, Li C, Li X
ACS nano 2024 May 28;18(21):13583-13598
ACS nano 2024 May 28;18(21):13583-13598
An integrated network pharmacology, molecular docking and experiment validation study to investigate the potential mechanism of Isobavachalcone in the treatment of osteoarthritis.
Fan Y, Yin L, Zhong X, He Z, Meng X, Chai F, Kong M, Zhang Q, Xia C, Tong Y, Bi Q
Journal of ethnopharmacology 2024 May 23;326:117827
Journal of ethnopharmacology 2024 May 23;326:117827
Mechanistic study of acupuncture on the pterygopalatine ganglion to improve allergic rhinitis: analysis of multi-target effects based on bioinformatics/network topology strategie.
Tian M, Sun W, Mao Y, Zhang Y, Liu H, Tang Y
Briefings in bioinformatics 2024 May 23;25(4)
Briefings in bioinformatics 2024 May 23;25(4)
Glycyrrhizic Acid Alleviates Semen Strychni-Induced Neurotoxicity Through the Inhibition of HMGB1 Phosphorylation and Inflammatory Responses.
Yu C, Xiang Y, Zhang M, Wen J, Duan X, Wang L, Deng G, Fang P
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 21;19(1):21
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 May 21;19(1):21
Inhibition of Nogo-B reduces the progression of pancreatic cancer by regulation NF-κB/GLUT1 and SREBP1 pathways.
Wang T, Zhang M, Gong X, Chen W, Peng Y, Liao C, Xu H, Li Q, Shen G, Ren H, Zhu Y, Zhang B, Mao J, Wei L, Chen Y, Yang X
iScience 2024 May 17;27(5):109741
iScience 2024 May 17;27(5):109741
Oxidized DJ-1 activates the p-IKK/NF-κB/Beclin1 pathway by binding PTEN to induce autophagy and exacerbate myocardial ischemia-reperfusion injury.
Liu H, Wang X, He K, Chen Z, Li X, Ren J, Zhao X, Liu S, Zhou T, Chen H
European journal of pharmacology 2024 May 15;971:176496
European journal of pharmacology 2024 May 15;971:176496
The role of FGF-21 in promoting diabetic wound healing by modulating high glucose-induced inflammation.
Li Z, Qiu X, Guan G, Shi K, Chen S, Tang J, Xiao M, Tang S, Yan Y, Zhou J, Xie H
Heliyon 2024 May 15;10(9):e30022
Heliyon 2024 May 15;10(9):e30022
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Han X, Wei J, Zheng R, Tu Y, Wang M, Chen L, Xu Z, Zheng L, Zheng C, Shi Q, Ying H, Liang G
Diabetes 2024 May 1;73(5):780-796
Diabetes 2024 May 1;73(5):780-796
Salvianolic acid B attenuates diabetic nephropathy through alleviating ADORA2B, NALP3 in flammasome, and NFκB activity.
Wang Y, Chang J, Qiao S, Yang Y, Yun C, Li Y, Wang F
Canadian journal of physiology and pharmacology 2024 May 1;102(5):318-330
Canadian journal of physiology and pharmacology 2024 May 1;102(5):318-330
Mammalian STE20-like kinase 1 inhibits synoviocytes activation in rheumatoid arthritis through mitochondrial dysfunction mediated by SIRT3/mTOR axis.
Tan M, Mao J, Zheng J, Meng Y, Li J, Hao J, Shen H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Mar;73(3):415-432
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Mar;73(3):415-432
Comparison between hangeshashinto and dexamethasone for IL-1α and β-defensin 1 production by human oral keratinocytes.
Hato H, Kaneko A, Maeda C, Sakata KI, Ono Y, Mizukami Y, Kono T, Kitagawa Y
Journal of oral biosciences 2024 Mar;66(1):188-195
Journal of oral biosciences 2024 Mar;66(1):188-195
Tetramethylpyrazine inhibits the inflammatory response by downregulating the TNFR1/IκB-α/NF-κB p65 pathway after spinal cord injury.
Liu G, Huo L, Deng B, Jiang S, Zhao Y, Mo Y, Bai H, Xu L, Hu C, Mu X
Toxicology and applied pharmacology 2024 Mar;484:116872
Toxicology and applied pharmacology 2024 Mar;484:116872
Amelioration of obesity and inflammation by polysaccharide from unripe fruits of raspberry via gut microbiota regulation.
Huang Y, Hu J, Xia Q, Tang M, Wang Y, Wang G, Shao X, Yuan H, Li S, Huang P, Peng C, Guo J, Gui S
International journal of biological macromolecules 2024 Mar;261(Pt 2):129825
International journal of biological macromolecules 2024 Mar;261(Pt 2):129825
VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Miao J, Tu Y, Jiang J, Ren R, Wu Q, Liang H, Wang T, Lin B, Wu J, Pan Y, Wang X, Jin H
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits.
Zhou J, Li C, Lu M, Jiang G, Chen S, Li H, Lu K
PLoS biology 2024 Mar;22(3):e3002537
PLoS biology 2024 Mar;22(3):e3002537
Correlational analysis of PLIN1 with inflammation in diabetic foot ulcer wounds.
Wang M, Cao X, Shang Y, Jiang Y, Chen P, Duan C, Zhang D, Wang P, Ji J, Gong Z
Diabetes research and clinical practice 2024 Mar;209:111605
Diabetes research and clinical practice 2024 Mar;209:111605
Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-κB pathway.
Li G, Liu X, Sun X, Huang L, Kuang W, Ou J, Zhang J, Zhang Z, Li H, Tang H, Feng C, Gu L, Yang C, Peili W, Wang J
Environment international 2024 Mar;185:108543
Environment international 2024 Mar;185:108543
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Wei X, Shi Y, Wang S, Liu H, Zhang Z, Yu L, Hua W, Cui D, Chen Y, Li X, Wang W
Fish & shellfish immunology 2024 Mar;146:109398
Fish & shellfish immunology 2024 Mar;146:109398
Regulatory effects of mangiferin on LPS-induced inflammatory responses and intestinal flora imbalance during sepsis.
Chang BT, Wang Y, Tu WL, Zhang ZQ, Pu YF, Xie L, Yuan F, Gao Y, Xu N, Yao Q
Food science & nutrition 2024 Mar;12(3):2068-2080
Food science & nutrition 2024 Mar;12(3):2068-2080
OR11H1 Missense Variant Confers the Susceptibility to Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression.
Li X, Wang G, Wang X, Li W, Li N, Liu X, Fan W, He S, Han Y, Su G, Cao Q, Yang P, Hou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2306563
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2306563
Caffeic acid-grafted chitooligosaccharides downregulate MAPK and NF-kB in RAW264.7 cells.
Bui VH, Vo HN, Kim SK, Ngo DN
Chemical biology & drug design 2024 Mar;103(3):e14496
Chemical biology & drug design 2024 Mar;103(3):e14496
MSR405: Inhibiting Neuroinflammation after Spinal Cord Injury in Rats.
Liu Y, Xiao Y, Gao J, Gao J, Li R, Qi Z, Liu X
Biomedicines 2024 Mar 8;12(3)
Biomedicines 2024 Mar 8;12(3)
Linoleic acid induces human ovarian granulosa cell inflammation and apoptosis through the ER-FOXO1-ROS-NFκB pathway.
Zhang W, Wu F
Scientific reports 2024 Mar 16;14(1):6392
Scientific reports 2024 Mar 16;14(1):6392
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity.
Liu S, Wang B, Lin L, Xu W, Gong ZH, Xiao WJ
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Journal of the science of food and agriculture 2024 Mar 15;104(4):2059-2072
Epigallocatechin-3-gallate protects sepsis-induced myocardial dysfunction by inhibiting the nuclear factor-κB signaling pathway.
Chen B, Li YF, Fang Z, Cai WY, Tian ZQ, Li D, Wang ZM
Heliyon 2024 Mar 15;10(5):e27163
Heliyon 2024 Mar 15;10(5):e27163
Baiheqingjin formula reduces inflammation in mice with asthma by inhibiting the PI3K/AKT/NF-κb signaling pathway.
Yan X, Tong X, Jia Y, Zhao Y, Zhang Q, Hu M, Li X, Li B, Ming X, Xie Y, Wu X, Yu X, Qu L, Xiong L, Huang F, Nie J
Journal of ethnopharmacology 2024 Mar 1;321:117565
Journal of ethnopharmacology 2024 Mar 1;321:117565
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
Wang J, He W, Yue H, Zhao P, Li J
Journal of ethnopharmacology 2024 Mar 1;321:117537
Journal of ethnopharmacology 2024 Mar 1;321:117537
Study on the effect and mechanism of Zhenzhu Tongluo pills in treating diabetic peripheral neuropathy injury.
Dong P, Zhou L, Wang X, Xue L, Du Y, Cui R
European journal of medical research 2024 Mar 1;29(1):149
European journal of medical research 2024 Mar 1;29(1):149
Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.
Wang C, Zeng W, Wang L, Xiong X, Chen S, Huang Q, Zeng G, Huang Q
Drug development research 2024 Jun;85(4):e22213
Drug development research 2024 Jun;85(4):e22213
SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1.
Wang H, Chen W, Wang Y, Gao Y, Zhang Z, Mi S, Wang L, Xue M
Science China. Life sciences 2024 Jun;67(6):1199-1211
Science China. Life sciences 2024 Jun;67(6):1199-1211
BMSC-derived exosomes regulate the Treg/Th17 balance through the miR-21-5p/TLR4/MyD88/NF-κB pathway to alleviate dry eye symptoms in mice.
Zhao D, Ji H, Zhao H, Xu Y, He A, He Y
In vitro cellular & developmental biology. Animal 2024 Jun;60(6):644-656
In vitro cellular & developmental biology. Animal 2024 Jun;60(6):644-656
Neutrophil Extracellular Traps Induce Pyroptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the NF-κB/Caspase 3/GSDME Pathway.
Mao J, Tan M, Li J, Liu C, Hao J, Zheng J, Shen H
Inflammation 2024 Jun;47(3):921-938
Inflammation 2024 Jun;47(3):921-938
Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer.
Wang B, Zhang S, Wang H, Wang M, Tao Y, Ye M, Fan Z, Wang Y, Liu L
Cancer gene therapy 2024 Jun;31(6):871-883
Cancer gene therapy 2024 Jun;31(6):871-883
The hsa_circ_0082152 maintains NF-κB mRNA stability by binding to MTDH to promote anti-tuberculosis drug-induced liver injury.
Wang L, Meng C, Long Y, Liu Y, Yang L, Gao X, Sun S, Feng F
International journal of biological macromolecules 2024 Jun;269(Pt 1):131793
International journal of biological macromolecules 2024 Jun;269(Pt 1):131793
Platelet-rich plasma alleviates knee arthritis in rats by inhibiting p65.
Zhuo F, Jia X, Wang Z, Zhang Y, Yan X
Cell and tissue banking 2024 Jun;25(2):463-473
Cell and tissue banking 2024 Jun;25(2):463-473
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Bai X, Deng J, Duan Z, Fu R, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Wang Y, Wang S, Wang Y, Wang C, Tang Y, Zhang C, Hou S, Yu D, Lin N
Cellular signalling 2024 Jun;118:111137
Cellular signalling 2024 Jun;118:111137
Calmodulin Contributes to Lipolysis and Inflammatory Responses in Clinical Ketosis Cows through the TLR4/IKK/NF-κB Pathway.
Chang J, Wang Z, Hao Y, Song Y, Xia C
Animals : an open access journal from MDPI 2024 Jun 4;14(11)
Animals : an open access journal from MDPI 2024 Jun 4;14(11)
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Tian X, Li J, Liu S, Dong Q, Fu Y, Luo R, Sun Y, Guo L, Lu Q, Ye C, Liu J, Fu S, Qiu Y
Heliyon 2024 Jun 30;10(12):e33161
Heliyon 2024 Jun 30;10(12):e33161
Sorcin Inhibits Mitochondrial Apoptosis by Interacting with STAT3 via NF-κB Pathway.
Li Y, Tian M, Pires Sanches JG, Zhang Q, Hou L, Zhang J
International journal of molecular sciences 2024 Jun 29;25(13)
International journal of molecular sciences 2024 Jun 29;25(13)
The effect of miR‑155‑5p on long‑term memory of sleep‑deprived mice through the BDNF/NF‑κB pathway.
Hou D, Zhong J, Hu Y, Yang G
Acta neurobiologiae experimentalis 2024 Jun 28;84(2):203-217
Acta neurobiologiae experimentalis 2024 Jun 28;84(2):203-217
The Combination of Bacillus natto JLCC513 and Ginseng Soluble Dietary Fiber Attenuates Ulcerative Colitis by Modulating the LPS/TLR4/NF-κB Pathway and Gut Microbiota.
Ma M, Li Y, He Y, Li D, Niu H, Sun M, Miao X, Su Y, Zhang H, Hua M, Wang J
Journal of microbiology and biotechnology 2024 Jun 28;34(6):1287-1298
Journal of microbiology and biotechnology 2024 Jun 28;34(6):1287-1298
Macrophage biomimetic nanoparticle-targeted functional extracellular vesicle micro-RNAs revealed via multiomics analysis alleviate sepsis-induced acute lung injury.
Wang G, Ma X, Huang W, Wang S, Lou A, Wang J, Tu Y, Cui W, Zhou W, Zhang W, Li Y, Geng S, Meng Y, Li X
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Journal of nanobiotechnology 2024 Jun 23;22(1):362
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis.
Wang G, Xie W, Deng L, Huang X, Sun M, Liu W, Tang S
Chinese medicine 2024 Jun 19;19(1):88
Chinese medicine 2024 Jun 19;19(1):88
Gold Nanoparticle Delivery of Glut1 SiRNA Facilitates Glucose Starvation Therapy in Lung Cancer.
Li J, Yu J, Fang Q, Du Y, Zhang X
Chembiochem : a European journal of chemical biology 2024 Jun 17;25(12):e202400239
Chembiochem : a European journal of chemical biology 2024 Jun 17;25(12):e202400239
Cathelicidin-BF regulates the AMPK/SIRT1/NF-κB pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie.
Zhou H, Zou L, Ren H, Shen Z, Lin Y, Cai H, Zhang J
International immunopharmacology 2024 Jun 15;134:112201
International immunopharmacology 2024 Jun 15;134:112201
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
Liu K, Gu Y, Gu S, Song L, Hua S, Li D, Tang M
International immunopharmacology 2024 Jun 15;134:112199
International immunopharmacology 2024 Jun 15;134:112199
New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase.
Lou Y, Li Z, Zheng H, Yuan Z, Li W, Zhang J, Shen W, Gao Y, Ran N, Kong X, Feng S
International immunopharmacology 2024 Jun 15;134:112190
International immunopharmacology 2024 Jun 15;134:112190
Asprosin promotes vascular inflammation via TLR4-NFκB-mediated NLRP3 inflammasome activation in hypertension.
Ge R, Chen JL, Zheng F, Yin SM, Dai M, Wang YM, Chen Q, Li YH, Zhu GQ, Chen AD
Heliyon 2024 Jun 15;10(11):e31659
Heliyon 2024 Jun 15;10(11):e31659
Ultrashort wave diathermy inhibits pulmonary inflammation in mice with acute lung injury in a HSP70 independent way: a pilot study.
Yang X, Li K, Li M, Chen C, Yang X, Li J, Zhang H
Molecular biology reports 2024 Jun 14;51(1):750
Molecular biology reports 2024 Jun 14;51(1):750
YTHDC1 inhibits autophagy-dependent NF-κB signaling by stabilizing Beclin1 mRNA in macrophages.
Zhou L, Zhang L, Lv Y, Qian J, Huang L, Qu C
Journal of inflammation (London, England) 2024 Jun 14;21(1):22
Journal of inflammation (London, England) 2024 Jun 14;21(1):22
Transmissible gastroenteritis virus induces inflammatory responses via RIG-I/NF-κB/HIF-1α/glycolysis axis in intestinal organoids and in vivo.
Zhang Y, Yang N, Li Y, Tan C, Cai Y, Rui X, Liu Y, Fu Y, Liu G
Journal of virology 2024 Jun 13;98(6):e0046124
Journal of virology 2024 Jun 13;98(6):e0046124
An Isofibrous Diet with Fiber Konjac Glucomannan Ameliorates Salmonella typhimurium-Induced Colonic Injury by Regulating TLR2-NF-κB Signaling and Intestinal Microbiota in Mice.
Li J, Liu H, Fu H, Yang Y, Wu Z
Journal of agricultural and food chemistry 2024 Jun 12;72(23):13415-13430
Journal of agricultural and food chemistry 2024 Jun 12;72(23):13415-13430
Tissue-resident C1q + macrophages exert anti-aging potential through the Sirt1 pathway.
Liu L, Zhu L, Liang Q, Yu L, Hu L, Yu Y, Cheng X, Bao H
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jul;73(7):1069-1080
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jul;73(7):1069-1080
Lipoxin A(4) ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through activation of the ESR2/LPAR3/Nrf2 axis in synovial fibroblast-like synoviocytes.
Hu Z, Chen L, Zhao J, Zhang W, Jin Z, Sun Y, Li Z, Chang B, Shen P, Yang Y
Redox biology 2024 Jul;73:103143
Redox biology 2024 Jul;73:103143
20-hydroxyecdysone suppresses bladder cancer progression via inhibiting USP21: A mechanism associated with deubiquitination and degradation of p65.
Ma Q, Wu F, Liu X, Zhao C, Sun Y, Li Y, Zhang W, Ju H, Wang Y
Translational oncology 2024 Jul;45:101958
Translational oncology 2024 Jul;45:101958
Chitosan-modified dihydromyricetin liposomes promote the repair of liver injury in mice suffering from diabetes mellitus.
Ding Q, Liu X, Zhang S, Chai G, Ma S, Sun S, Shen L, Gao Y, Ding C, Zhao T, Liu W
International journal of biological macromolecules 2024 Jul;273(Pt 2):133040
International journal of biological macromolecules 2024 Jul;273(Pt 2):133040
GRP78 Downregulation in Keratinocytes Promotes Skin Inflammation through the Recruitment and Activation of CCR6(+) IL-17A-Producing γδ T Cells.
Zhao L, Li J, Jiang B, Yang J, Lan J, Li D, Wen J, Xia Y, Nie W, Wang Z, Lv Y, Zeng F, Li Y, Shen G, Lei P, Tao J
The Journal of investigative dermatology 2024 Jul;144(7):1557-1567.e11
The Journal of investigative dermatology 2024 Jul;144(7):1557-1567.e11
Essential oil from Cinnamomum cassia Presl bark regulates macrophage polarization and ameliorates lipopolysaccharide-induced acute lung injury through TLR4/MyD88/NF-κB pathway.
Liu F, Yang Y, Dong H, Zhu Y, Feng W, Wu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155651
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155651
Ethanolic extract of Arctium lappa leaves alleviates cerebral ischemia reperfusion-induced inflammatory injury via HDAC9-mediated NF-κB pathway.
Wang M, Li Q, Ren B, Hao D, Guo H, Yang L, Wang Z, Dai L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155599
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155599
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
Chen W, Xie X, Liu C, Liao J, Wei Y, Wu R, Hong J
Cellular signalling 2024 Jul;119:111192
Cellular signalling 2024 Jul;119:111192
Nonswellable Hydrogel Patch with Tissue-Mimetic Mechanical Characteristics Remodeling In Vivo Microenvironment for Effective Adhesion Prevention.
Liu X, Qiu X, Nie L, Zhou B, Bu P, Li Y, Xue X, Tang B, Feng Q, Cai K
ACS nano 2024 Jul 9;18(27):17651-17671
ACS nano 2024 Jul 9;18(27):17651-17671
Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis.
Liu Y, Luo H, Liu B, Zhou T, Zhang Z, Liu Z
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Biomacromolecules 2024 Jul 8;25(7):4557-4568
Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned Piglets.
Liu T, Ma W, Wang J, Wei Y, Wang Y, Luo Z, Zhang Y, Zeng X, Guan W, Shao D, Chen F
Antioxidants (Basel, Switzerland) 2024 Jul 8;13(7)
Antioxidants (Basel, Switzerland) 2024 Jul 8;13(7)
Uric acid-lowering effect of harpagoside and its protective effect against hyperuricemia-induced renal injury in mice.
Fu Q, Zhang JJ, Zhu QF, Yu LL, Wang F, Li J, He X, Ao JL, Xu GB, Wei MC, Liao XJ, Liao SG
Biochemical and biophysical research communications 2024 Jul 5;716:150038
Biochemical and biophysical research communications 2024 Jul 5;716:150038
Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury.
Nie X, Liu Y, Yuan T, Yu T, Yun Z, Xue W, Yu T, An J, Dai A, Wu K, Liu Q
Journal of nanobiotechnology 2024 Jul 31;22(1):456
Journal of nanobiotechnology 2024 Jul 31;22(1):456
Zhen-wu-tang protects against myocardial fibrosis by inhibiting M1 macrophage polarization via the TLR4/NF-κB pathway.
Fang R, Zhou R, Ju D, Li M, Wang H, Pan L, Wang X, Han M, Yu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155719
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Jiang T, Sun L, Wang Y, Zhang F, Guo J, Sun L, Jiang Y, Xue J, Duan J, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155655
GM1 Ameliorates Neuronal Injury in Rats after Cerebral Ischemia and Reperfusion: Potential Contribution of Effects on SPTBN1-mediated Signaling.
Shi YW, Xu CC, Sun CY, Liu JX, Zhao SY, Liu D, Fan XJ, Wang CP
Neuroscience 2024 Jul 23;551:103-118
Neuroscience 2024 Jul 23;551:103-118
Exploring the Mechanism of Asiatic Acid against Atherosclerosis Based on Molecular Docking, Molecular Dynamics, and Experimental Verification.
Wu Z, Yang L, Wang R, Yang J, Liang P, Ren W, Yu H
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
Pharmaceuticals (Basel, Switzerland) 2024 Jul 22;17(7)
Weissella paramesenteroides NRIC1542 inhibits dextran sodium sulfate-induced colitis in mice through regulating gut microbiota and SIRT1/NF-κB signaling pathway.
Li S, Chen J, Zheng Y, Zhang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23791
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23791
The protective effects of aqueous extract of Schisandra sphenanthera against alcoholic liver disease partly through the PI3K-AKT-IKK signaling pathway.
Liu D, Yang K, Li T, Tang T, Wang Y, Wang W, Li J, Zhou P, Wang X, Zhao C, Guo D, Xie Y, Cheng J, Wang M, Sun J, Zhang X
Heliyon 2024 Jul 15;10(13):e34214
Heliyon 2024 Jul 15;10(13):e34214
Lysophosphatidylcholine trigger myocardial injury in diabetic cardiomyopathy via the TLR4/ZNF480/AP-1/NF-kB pathway.
Liu N, Chen Y, An T, Tao S, Lv B, Dou J, Deng R, Zhen X, Zhang Y, Lu C, Chang Z, Jiang G
Heliyon 2024 Jul 15;10(13):e33601
Heliyon 2024 Jul 15;10(13):e33601
Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis.
Zhang W, Zhong Y, Wang Z, Tang F, Zheng C
Scientific reports 2024 Jul 13;14(1):16215
Scientific reports 2024 Jul 13;14(1):16215
ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway.
Ji Y, Ni C, Shen Y, Xu Z, Tang L, Yu F, Zhu L, Lu H, Zhang C, Yang S, Wang X
Molecular cancer 2024 Jul 11;23(1):143
Molecular cancer 2024 Jul 11;23(1):143
Multi-omics analyses reveal bacteria and catalase associated with keloid disease.
Shan M, Xiao M, Xu J, Sun W, Wang Z, Du W, Liu X, Nie M, Wang X, Liang Z, Liu H, Hao Y, Xia Y, Zhu L, Song K, Feng C, Meng T, Wang Z, Cao W, Wang L, Zheng Z, Wang Y, Huang Y
EBioMedicine 2024 Jan;99:104904
EBioMedicine 2024 Jan;99:104904
Anti-inflammatory activities of several diterpenoids isolated from Hemionitis albofusca.
Pei X, Lou Y, Ren Q, Liu Y, Dai X, Ye M, Huang G, Cao J
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):437-449
Lixisenatide ameliorated lipopolysaccharide (LPS)-induced expression of mucin and inflammation in bronchial epithelial cells.
Xu L, Chen G, Zhang L, He A, Li Y
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23618
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23618
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Zhang J, Su L, Liu Z, Tang J, Zhang L, Li Z, Zhou D, Sun Z, Xi K, Lu P, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells.
Zeng F, Li Y, Zhang X, Shen L, Zhao X, Beta T, Li B, Chen R, Huang W
International journal of biological macromolecules 2024 Jan;254(Pt 2):127700
International journal of biological macromolecules 2024 Jan;254(Pt 2):127700
Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Xia K, Guo J, Yu B, Wang T, Qiu Q, Chen Q, Qiu T, Zhou J, Zheng S
Free radical biology & medicine 2024 Jan;210:378-389
Free radical biology & medicine 2024 Jan;210:378-389
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
Lv K, Lou P, Liu S, Wang Y, Yang J, Zhou P, Zhou X, Lu Y, Wang H, Cheng J, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.
Zhang J, Tu Y, Wei J, Zheng R, Shao J, Chen Q, Liang G, Ying H, Han X, Shi Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166911
Allograft inflammatory factor-1 enhances inflammation and oxidative stress via the NF-κB pathway of bladder urothelium in diabetic rat model.
Wu Q, Qin B, Wu X, Zhang M, Gan Z, Lan Y, Ma C, Fu W
Cytokine 2024 Jan;173:156438
Cytokine 2024 Jan;173:156438
Protective effects of sodium humate on the intestinal barrier damage of Salmonella Typhimurium-challenged broilers.
Ma W, Zou X, Sun X, Wang W, Liu K, He Y, Liu Y, Wang D
Animal science journal = Nihon chikusan Gakkaiho 2024 Jan-Dec;95(1):e14004
Animal science journal = Nihon chikusan Gakkaiho 2024 Jan-Dec;95(1):e14004
Selection and Characterization of a DNA Aptamer Recognizing High Mobility Group Box 1 Protein (HMGB1) and Enhancing Its Pro-inflammatory Activity.
Li H, Sun W, Huang Y, Li Q, Tian H, Hao Z, Huo Y
Iranian journal of pharmaceutical research : IJPR 2024 Jan-Dec;23(1):e147246
Iranian journal of pharmaceutical research : IJPR 2024 Jan-Dec;23(1):e147246
Grape seed-derived procyanidins decreases neuropathic pain and nerve regeneration by suppression of toll-like receptor 4-myeloid differentiation factor-88 signaling.
Hu L, An E, Zhu Z, Cai Y, Ye X, Zhou H, Ge H
Molecular pain 2024 Jan-Dec;20:17448069241256466
Molecular pain 2024 Jan-Dec;20:17448069241256466
Gut microbiota regulates host melatonin production through epithelial cell MyD88.
Liu B, Fan L, Wang Y, Wang H, Yan Y, Chen S, Hung I, Liu C, Wei H, Ge L, Ren W
Gut microbes 2024 Jan-Dec;16(1):2313769
Gut microbes 2024 Jan-Dec;16(1):2313769
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Zhao WM, Li XL, Zhu Y, Shi R, Wang ZJ, Xiao JP, Wang DG
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma.
Wang J, Ma C, Tang Z, Sun Z, Qaed E, Chi X, Wang J, Jamalat Y, Geng Z, Tang Z, Yao Q
Cancer cell international 2024 Jan 7;24(1):17
Cancer cell international 2024 Jan 7;24(1):17
Baicalin exerts neuroprotective actions by regulating the Nrf2-NLRP3 axis in toxin-induced models of Parkinson's disease.
Huang J, Zhang X, Yang X, Yv Q, Ye F, Chen S, Cui Y, Gu L, Zhu M, Li W
Chemico-biological interactions 2024 Jan 5;387:110820
Chemico-biological interactions 2024 Jan 5;387:110820
Carveol alleviates osteoarthritis progression by acting on synovial macrophage polarization transformation: An in vitro and in vivo study.
Chen S, Xu H, He Y, Meng C, Fan Y, Qu Y, Wang Y, Zhou W, Huang X, You H
Chemico-biological interactions 2024 Jan 5;387:110781
Chemico-biological interactions 2024 Jan 5;387:110781
Free heme induces neuroinflammation and cognitive impairment by microglial activation via the TLR4/MyD88/NF-κB signaling pathway.
Wei X, Zhang F, Cheng D, Wang Z, Xing N, Yuan J, Zhang W, Xing F
Cell communication and signaling : CCS 2024 Jan 5;22(1):16
Cell communication and signaling : CCS 2024 Jan 5;22(1):16
Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice.
Cheng M, Zheng Y, Wu G, Tan L, Xu F, Zhang Y, Chen X, Zhu K
Nutrients 2024 Jan 4;16(1)
Nutrients 2024 Jan 4;16(1)
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Lang Y, Wang Q, Sheng Q, Lu S, Yang M, Kong Z, Gao Y, Fan X, Shen N, Wang R, Lv Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway.
Jin H, Liu C, Liu X, Wang H, Zhang Y, Liu Y, Li J, Yu Z, Liu HX
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117270
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis.
Wu W, Li G, Dong S, Huihan Chu C, Ma S, Zhang Z, Yuan S, Wu J, Guo Z, Shen Y, Wang J, Tang C
International immunopharmacology 2024 Jan 25;127:111423
International immunopharmacology 2024 Jan 25;127:111423
Diallyl trisulfide inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung cancer via modulating gut microbiota and the PPARγ/NF-κB pathway.
Qu Z, Tian J, Sun J, Shi Y, Yu J, Zhang W, Zhuang C
Food & function 2024 Jan 2;15(1):158-171
Food & function 2024 Jan 2;15(1):158-171
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
Cui C, Wei Y, Wang Y, Ma W, Zheng X, Wang J, Ma Z, Wu C, Chu L, Zhang S, Guan W, Chen F
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
Lactate dehydrogenase A promotes nasopharyngeal carcinoma progression through the TAK1/NF-κB Axis.
Li Y, Chen L, Zheng Q, Liu G, Wang M, Wei S, Chen T
Molecular biology reports 2024 Jan 18;51(1):152
Molecular biology reports 2024 Jan 18;51(1):152
Neutrophil extracellular trap-related mechanisms in acne vulgaris inspire a novel treatment strategy with adipose-derived stem cells.
Yu H, Zhang B, Zhan Y, Yi Y, Jiang Q, Zhang Q, Wu Y, Wu M
Scientific reports 2024 Jan 17;14(1):1521
Scientific reports 2024 Jan 17;14(1):1521
The protective effect of Schisandra chinensis (Turcz.) Baill. polysaccharide on DSS-induced ulcerative colitis in mice via the modulation of gut microbiota and inhibition of NF-κB activation.
Guo X, Liu L, Zhao W, Li X, Wang X, Ning A, Cao J, Zhang W, Cao L, Zhong M
Journal of the science of food and agriculture 2024 Jan 15;104(1):196-206
Journal of the science of food and agriculture 2024 Jan 15;104(1):196-206
An exploration of the effect of Chinese herbal compound on the occurrence and development of large intestine cancer and intestinal flora.
Liu P, Ying J, Guo X, Tang X, Zou W, Wang T, Xu X, Zhao B, Song N, Cheng J
Heliyon 2024 Jan 15;10(1):e23533
Heliyon 2024 Jan 15;10(1):e23533
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Wu DZ, Zhu GZ, Zhao K, Gao JW, Cai GX, Li HZ, Huang YS, Tu C, Zhuang JS, Huang ZW, Zhong ZM
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Effects and mechanisms of Zhizi Chuanxiong herb pair against atherosclerosis: an integration of network pharmacology, molecular docking, and experimental validation.
Zhang Y, Qi Y, Jia Z, Li Y, Wu L, Zhou Q, Xu F
Chinese medicine 2024 Jan 11;19(1):8
Chinese medicine 2024 Jan 11;19(1):8
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin.
Wu LR, Peng QY, Li XJ, Guo MY, He JQ, Ying HZ, Yu CH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117056
Yang-Xin-Shu-Mai granule alleviates atherosclerosis by regulating macrophage polarization via the TLR9/MyD88/NF-κB signaling pathway.
Huang H, Sun Z, Xu J, Wang L, Zhao J, Li J, Zhang S, Yuan F, Liu M, Fang Z
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116868
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116868
Partial Replacement of NaCl with KCl in Cooked Meat Could Reduce the Liver Damage Through Renin-Angiotensin System in Mice.
Zou L, Yu X, Xiong J, Chen C, Xiao G
Molecular nutrition & food research 2024 Feb;68(4):e2200783
Molecular nutrition & food research 2024 Feb;68(4):e2200783
Exosomes Derived from Quercetin-Treated Bone Marrow Derived Mesenchymal Stem Cells Inhibit the Progression of Osteoarthritis Through Delivering miR-124-3p to Chondrocytes.
Dong S, Xu G, Li X, Guo S, Bai J, Zhao J, Chen L
DNA and cell biology 2024 Feb;43(2):85-94
DNA and cell biology 2024 Feb;43(2):85-94
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
Oral administration of punicalagin attenuates imiquimod-induced psoriasis by reducing ROS generation and inflammation via MAPK/ERK and NF-κB signaling pathways.
Wang Y, Han D, Huang Y, Dai Y, Wang Y, Liu M, Wang N, Yin T, Du W, He K, Zheng Y
Phytotherapy research : PTR 2024 Feb;38(2):713-726
Phytotherapy research : PTR 2024 Feb;38(2):713-726
Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines.
Jiang X, Liu H, You Y, Zhong G, Ruan Z, Liao J, Zhang H, Pan J, Tang Z, Hu L
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Feb;276:109815
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2024 Feb;276:109815
In vitro and in vivo immunomodulatory activity of acetylated polysaccharides from Cyclocarya paliurus leaves.
Zhang Y, Zhao M, He J, Chen L, Wang W
International journal of biological macromolecules 2024 Feb;259(Pt 1):129174
International journal of biological macromolecules 2024 Feb;259(Pt 1):129174
In vitro and in vivo biological evaluation of Lappaconitine derivatives as potential anti-inflammatory agents.
Xiao Y, Han M, Chen Y, Li YZ, Zhang YY, Chen L, Huang S, Zhou XL
Chemistry & biodiversity 2024 Feb;21(2):e202301761
Chemistry & biodiversity 2024 Feb;21(2):e202301761
MMP14(high) macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis.
Peng D, Li J, Li Y, Bai L, Xiong A, He X, Li X, Ran Q, Zhang L, Jiang M, Wang J, Leung EL, Yang P, Li G
Pharmacological research 2024 Feb;200:107070
Pharmacological research 2024 Feb;200:107070
Attenuation of pro-tumorigenic senescent secretory phenotype by StN, a novel derivative of stevioside, potentiates its inhibitory activity on hepatocellular carcinoma.
Guo Y, Wang S, Dong Y, Liu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114371
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114371
Isoflavones isolated from chickpea sprouts alleviate ovariectomy-induced osteoporosis in rats by dual regulation of bone remodeling.
Huang J, Zheng J, Dadihanc T, Gao Y, Zhang Y, Li Z, Wang X, Yu L, Mijiti W, Xie Z, Ma H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116214
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116214
Exploration of costunolide derivatives as potential anti-inflammatory agents for topical treatment of atopic dermatitis by inhibiting MAPK/NF-κB pathways.
Lu C, Li X, Du W, Zhang X, Li Y, Hu C, Mao Z, Zhang Y, Wang R
Bioorganic chemistry 2024 Feb;143:107054
Bioorganic chemistry 2024 Feb;143:107054
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hui H, Wang Z, Zhao X, Xu L, Yin L, Wang F, Qu L, Peng J
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Shi C, Zhang Y, Wu G, Zhu Z, Zheng H, Sun X, Heng Y, Pan S, Xiu H, Zhang J, Yin Z, Yu Z, Liang B
Advanced healthcare materials 2024 Feb;13(4):e2302626
Advanced healthcare materials 2024 Feb;13(4):e2302626
Palmatine ameliorated lipopolysaccharide-induced sepsis-associated encephalopathy mice by regulating the microbiota-gut-brain axis.
Xu Y, Shen B, Pan X, Liu C, Wang Y, Chen X, Wang T, Chen G, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155307
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155307
Atypical inflammatory kinase IKBKE phosphorylates and inactivates FoxA1 to promote liver tumorigenesis.
Gao B, Wu X, Bu L, Jiang Q, Wang L, Liu H, Zhang X, Wu Y, Li X, Li J, Liang Y, Xu L, Xie W, Guo J
Science advances 2024 Feb 9;10(6):eadk2285
Science advances 2024 Feb 9;10(6):eadk2285
Astragalus polysaccharide improves diabetic ulcers by promoting M2-polarization of macrophages to reduce excessive inflammation via the β-catenin/ NF-κB axis at the late phase of wound-healing.
Zhen Z, Wei S, Yunfei W, Jie X, Jienan X, Yiting S, Wen X, Shuyu G, Yue L, Xuanyu W, Yumei Z, Huafa Q
Heliyon 2024 Feb 29;10(4):e24644
Heliyon 2024 Feb 29;10(4):e24644
Osteostatin Mitigates Gouty Arthritis through the Inhibition of Caspase-1 Activation and Upregulation of Nrf2 Expression.
Catalán L, Carceller MC, Terencio MC, Alcaraz MJ, Ferrándiz ML, Montesinos MC
International journal of molecular sciences 2024 Feb 27;25(5)
International journal of molecular sciences 2024 Feb 27;25(5)
Mitochondrial reactive oxygen species initiate gasdermin D-mediated pyroptosis and contribute to paraquat-induced nephrotoxicity.
Chen K, Li M, Tang Y, Lu Z
Chemico-biological interactions 2024 Feb 25;390:110873
Chemico-biological interactions 2024 Feb 25;390:110873
Assessing the effects of tempol on renal fibrosis, inflammation, and oxidative stress in a high-salt diet combined with 5/6 nephrectomy rat model: utilizing oxidized albumin as a biomarker.
Liu B, Hu Y, Tian D, Dong J, Li BF
BMC nephrology 2024 Feb 23;25(1):64
BMC nephrology 2024 Feb 23;25(1):64
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Adzraku SY, Cao C, Zhou Q, Yuan K, Hao X, Li Y, Yuan S, Huang Y, Xu K, Qiao J, Ju W, Zeng L
Cell death & disease 2024 Feb 21;15(2):159
Cell death & disease 2024 Feb 21;15(2):159
Knockdown of DNMT1 Induces SLCO3A1 to Promote Follicular Growth by Enhancing the Proliferation of Granulosa Cells in Mammals.
Li S, Zeng L, Miao F, Li N, Liao W, Zhou X, Chen Y, Quan H, He Y, Zhang H, Li J, Yuan X
International journal of molecular sciences 2024 Feb 20;25(5)
International journal of molecular sciences 2024 Feb 20;25(5)
Transcriptotype-Driven Discovery of Apigenin as a Therapy against Cholestatic Liver Fibrosis: Through Inhibition of PANoptosis and Following Type-I Interferon Responses.
Duan S, Li X, Han J, Yang Y, Luo R, Cai Y, Li X, Zheng Q, Guo J, Liu R
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 20;13(3)
The Pea Oligosaccharides Could Stimulate the In Vitro Proliferation of Beneficial Bacteria and Enhance Anti-Inflammatory Effects via the NF-κB Pathway.
Cheng Y, Zhao R, Qiao M, Ma Y, Li T, Li N, Shen Y, Huang X, Song L
Foods (Basel, Switzerland) 2024 Feb 19;13(4)
Foods (Basel, Switzerland) 2024 Feb 19;13(4)
Dendrobium officinale Polysaccharides as a Natural Functional Component for Acetic-Acid-Induced Gastric Ulcers in Rats.
Zhang M, Xu L, Chen L, Wu H, Jia L, Zhu H
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
S100A4/NF-κB axis mediates the anticancer effect of epigallocatechin-3-gallate in platinum-resistant ovarian cancer.
Li X, Hou Y, Han G, Yang Y, Wang S, Lv X, Gao M
iScience 2024 Feb 16;27(2):108885
iScience 2024 Feb 16;27(2):108885
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Wang Y, Lou P, Xie Y, Liu S, Li L, Wang C, Du D, Chen Y, Lu Y, Cheng J, Liu J
Science advances 2024 Feb 16;10(7):eadj1290
Science advances 2024 Feb 16;10(7):eadj1290
Serine synthesis sustains macrophage IL-1β production via NAD(+)-dependent protein acetylation.
Wang C, Chen Q, Chen S, Fan L, Gan Z, Zhao M, Shi L, Bin P, Yang G, Zhou X, Ren W
Molecular cell 2024 Feb 15;84(4):744-759.e6
Molecular cell 2024 Feb 15;84(4):744-759.e6
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Cheng X, Chen J, Guo X, Cao H, Zhang C, Hu G, Zhuang Y
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway.
Li Q, Xiao C, Gu J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2024 Feb 15;128:111459
International immunopharmacology 2024 Feb 15;128:111459
The involvement of Neuregulin-1 in the process of facial nerve injury repair through the utilization of dental pulp stem cells.
Yao L, Xu W, Liu L, Xu X, Xi H, Xue B, Cao X, Lin S, Piao G, Sun J, Wang X
BMC oral health 2024 Feb 14;24(1):238
BMC oral health 2024 Feb 14;24(1):238
Sasanquasaponin from Camellia oleifera Abel Exerts an Anti-Inflammatory Effect in RAW 264.7 Cells via Inhibition of the NF-κB/MAPK Signaling Pathways.
Zhao Y, Zhao N, Kollie L, Yang D, Zhang X, Zhang H, Liang Z
International journal of molecular sciences 2024 Feb 10;25(4)
International journal of molecular sciences 2024 Feb 10;25(4)
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Yang D, Wu W, Lu Q, Mou Y, Chen W, Wan S, Zhang M, Wang C, Du X, Li N, Hua J
Stress biology 2024 Feb 1;4(1):9
Stress biology 2024 Feb 1;4(1):9
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice.
Liu MY, Xu KH, Liu S, Xiao WJ
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Molecular nutrition & food research 2024 Dec;68(23):e2400766
Runx2 Suppresses Astrocyte Activation and Astroglial Scar Formation After Spinal Cord Injury in Mice.
Lu L, Ye J, Yi D, Qi T, Luo T, Wu S, Yang L, Li L, Zhang H, Chen D
Molecular neurobiology 2024 Dec;61(12):10820-10829
Molecular neurobiology 2024 Dec;61(12):10820-10829
Pseudorabies virus UL13 primes inflammatory response through downregulating heat shock factor 1.
Zhang WJ, Feng H, Zhang MM, Liu JS, Li LT, Chen HC, Liu ZF
Virology 2024 Dec;600:110214
Virology 2024 Dec;600:110214
Hypothermic oxygenated perfusion inhibits CLIP1-mediated TIRAP ubiquitination via TFPI2 to reduce ischemia‒reperfusion injury of the fatty liver.
Yue P, Lv X, Cao H, Zou Y, You J, Luo J, Lu Z, Chen H, Liu Z, Zhong Z, Xiong Y, Fan X, Ye Q
Experimental & molecular medicine 2024 Dec;56(12):2588-2601
Experimental & molecular medicine 2024 Dec;56(12):2588-2601
G protein-coupled receptor kinase 2 as a novel therapeutic target for gland fibrosis of Sjögren's syndrome.
Fang RH, Zhou ZW, Chu R, Guan QY, He F, Ge ML, Guo PP, Wu HX, Yao LL, Wei W, Ma Y, Wang QT
Acta pharmacologica Sinica 2024 Dec;45(12):2611-2624
Acta pharmacologica Sinica 2024 Dec;45(12):2611-2624
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3β pathway.
Han YL, Yan TT, Li HX, Chen SS, Zhang ZZ, Wang MY, Chen MJ, Chen YL, Yang XX, Wei LL, Duan YJ, Zhang S
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Acta pharmacologica Sinica 2024 Dec;45(12):2567-2578
Zuyangping formula promotes skin wound healing in diabetic rats.
Junhua M, Hong Z, Yuling C, Yu Z, Xiong W, Bi S, Jing AN, Yonggang C
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Dec;44(6):1194-1203
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Dec;44(6):1194-1203
NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells.
Yang W, Jin M, Wang Y, Zhao H, Wang X, Guo Y, Li C, Xiao B, Zhang H, Kiran F, Wang A, Chao HW, Jin Y, Chen H
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
International journal of biological macromolecules 2024 Dec;283(Pt 4):137642
Chitosan-based self-healing thermosensitive hydrogel loaded with siHMGB1 for treatment of rheumatoid arthritis via macrophage repolarization.
Xu L, Qin J, Ma X, Wang Q, Wu W, Huang H, Cai L
International journal of biological macromolecules 2024 Dec;282(Pt 4):137102
International journal of biological macromolecules 2024 Dec;282(Pt 4):137102
Anti-inflammatory activity and underlying mechanism against sepsis-induced acute lung injury of a low-molecular-weight polysaccharide from the root of Stemona tuberosa Lour.
Qiu X, Geng Y, Cai X, Ou Y, Li M, Zhang Y, He D, Qian X, Wu Y, Ma H, Yan JK, Yao H, Chen WH
International journal of biological macromolecules 2024 Dec;282(Pt 1):136617
International journal of biological macromolecules 2024 Dec;282(Pt 1):136617
Pharmacological Network Analysis of the Functions and Mechanism of Quercetin From Jisuikang (JSK) in Spinal Cord Injury (SCI).
Dong L, He H, Chen Z, Wang X, Li Y, Lü G, Wang B, Kuang L
Journal of cellular and molecular medicine 2024 Dec;28(24):e70269
Journal of cellular and molecular medicine 2024 Dec;28(24):e70269
Paquinimod attenuates retinal injuries by suppressing the S100A9/TLR4 signaling in an experimental model of diabetic retinopathy.
Deng C, Li X, Ren M, Ye Z, Jin F, Yao B, Peng Y, Lu L, Dong K
Experimental eye research 2024 Dec;249:110131
Experimental eye research 2024 Dec;249:110131
Intestinal barrier, immunity and gut microbiota-based protective effects of Lactococcus lactis HF08 and its postbiotic derivative on aging and aging colitis mice.
Liu X, Ma Y, Guan K, Liu R, Mao K, Xu X, Li Q, Wang R
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115164
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115164
Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers.
Su Y, Chang G, Liu J, Huang P, Zeng J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Dec;19:76-89
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Dec;19:76-89
Baliosperoid A attenuates lipopolysaccharide-induced acute lung injury by targeting SHP2 to inhibit inflammation and oxidative stress.
Li Y, Zhao L, Liu Z, Chen Y, Li X, Zhu D, Liu L
Bioorganic chemistry 2024 Dec;153:107982
Bioorganic chemistry 2024 Dec;153:107982
New benzophenone analogs from Nigrospora sphaerica and their inhibitory activity against PD-1/PD-L1 interactions.
Kuang QX, Huang YQ, Ruan YQ, Lai HZ, Long J, Yan CY, Lei HR, Guo DL, Deng Y, You FM, Jiang YF
Bioorganic chemistry 2024 Dec;153:107899
Bioorganic chemistry 2024 Dec;153:107899
Biologically active franchetine-type diterpenoid alkaloids: Isolation, synthesis, anti-inflammatory, agalgesic activities, and molecular docking.
Xiao Y, Chang Y, Liu YY, Li TT, Qu WR, Yuan C, Chen L, Huang S, Zhou XL
Bioorganic chemistry 2024 Dec;153:107834
Bioorganic chemistry 2024 Dec;153:107834
Pterosin B improves cognitive dysfunction by promoting microglia M1/M2 polarization through inhibiting Klf5/Parp14 pathway.
Zhang Y, Chen JC, Zheng JH, Cheng YZ, Weng WP, Zhong RL, Sun SL, Shi YS, Pan XD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156152
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156152
Cardioprotective effects of polydatin against myocardial injury in HFD/stz and high glucose-induced diabetes via a Caveolin 1-dependent mechanism.
Gong W, Zhang N, Sun X, Zhang Y, Wang Y, Lv D, Luo H, Liu Y, Chen Z, Lei Q, Zhao G, Bai L, Jiao Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156055
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156055
Investigating the potential risk of cadmium exposure on seizure severity and anxiety-like behaviors through the ferroptosis pathway in epileptic mice: An integrated multi-omics approach.
Chang Y, Jiang X, Dou J, Xie R, Zhao W, Cao Y, Gao J, Yao F, Wu D, Mei H, Zhong Y, Ge Y, Xu H, Jiang W, Xiao X, Jiang Y, Hu S, Wu Y, Liu Y
Journal of hazardous materials 2024 Dec 5;480:135814
Journal of hazardous materials 2024 Dec 5;480:135814
A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling.
Wu Z, Yin Y, Liu R, Li X, Sun Y, Yau SY, Wu L, Liu Y, Adzic M, Zhang H, Chen G
Journal of ethnopharmacology 2024 Dec 5;335:118647
Journal of ethnopharmacology 2024 Dec 5;335:118647
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
Ma Z, Chen X, Xiong M, Wang H, Sun C, Tang W, Li J, Li X, Ma H, Ye X
Journal of ethnopharmacology 2024 Dec 5;335:118644
Journal of ethnopharmacology 2024 Dec 5;335:118644
Fucoidan from Laminaria japonica protects renal tubular epithelial cells from uric acid induced NLRP3-mediated pyroptosis through inhibition of NF-κB pathway.
Tan X, Zhang Y, Luo P, Lin Z, Li F, Liu H
Journal of ethnopharmacology 2024 Dec 5;335:118614
Journal of ethnopharmacology 2024 Dec 5;335:118614
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Zhang Z, Chen H, Li Q
International immunopharmacology 2024 Dec 5;142(Pt B):113235
International immunopharmacology 2024 Dec 5;142(Pt B):113235
Nuciferine ameliorates osteoarthritis: An in vitro and in vivo study.
Peng M, Shen G, Tu Q, Zhang W, Wang J
International immunopharmacology 2024 Dec 5;142(Pt B):113098
International immunopharmacology 2024 Dec 5;142(Pt B):113098
Toralactone alleviates cisplatin-induced acute kidney injury by modulating the gut microbiota-renal axis.
Tian Y, Tian R, He J, Guo Y, Yan P, Chen Y, Li R, Wang B
International immunopharmacology 2024 Dec 5;142(Pt A):113115
International immunopharmacology 2024 Dec 5;142(Pt A):113115
Kongensin A targeting PI3K attenuates inflammation-induced osteoarthritis by modulating macrophage polarization and alleviating inflammatory signaling.
Guo Y, Wang P, Hu B, Wang L, Zhang Y, Wang J
International immunopharmacology 2024 Dec 5;142(Pt A):112948
International immunopharmacology 2024 Dec 5;142(Pt A):112948
Intranasal administration of Clostridium butyricum and its derived extracellular vesicles alleviate LPS-induced acute lung injury.
Liu L, Zheng C, Xu Z, Wang Z, Zhong Y, He Z, Zhang W, Zhang Y
Microbiology spectrum 2024 Dec 5;12(12):e0210824
Microbiology spectrum 2024 Dec 5;12(12):e0210824
The facilitating effects of KRT80 on chemoresistance, lipogenesis, and invasion of esophageal cancer.
Yun WJ, Li J, Yin NC, Zhang CY, Cui ZG, Zhang L, Zheng HC
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Cancer biology & therapy 2024 Dec 31;25(1):2302162
Dual rectification of metabolism abnormality in pancreatic cancer by a programmed nanomedicine.
Wu B, Wang Z, Liu J, Li N, Wang X, Bai H, Wang C, Shi J, Zhang S, Song J, Li Y, Nie G
Nature communications 2024 Dec 3;15(1):10526
Nature communications 2024 Dec 3;15(1):10526
Neutrophil extracellular traps in rheumatoid arthritis: Activating fibroblast-like synoviocytes via ATP citrate lyase.
Li J, Wang X, Tan M, Zheng J, Mao J, Hao J, Shen H
International immunopharmacology 2024 Dec 25;143(Pt 3):113518
International immunopharmacology 2024 Dec 25;143(Pt 3):113518
Allosteric inhibition of the tyrosine phosphatase SHP2 enhances the anti-tumor immunity of interferon α through induction of caspase-1-mediated pyroptosis in renal cancer.
Xi R, Cao Y, Fu N, Sheng Y, Yu J, Li L, Zhang G, Wang F
International immunopharmacology 2024 Dec 25;143(Pt 2):113498
International immunopharmacology 2024 Dec 25;143(Pt 2):113498
Colorectal cancer cells establish metabolic reprogramming with cancer-associated fibroblasts (CAFs) through lactate shuttle to enhance invasion, migration, and angiogenesis.
Wang X, Qu Y, Ji J, Liu H, Luo H, Li J, Han X
International immunopharmacology 2024 Dec 25;143(Pt 2):113470
International immunopharmacology 2024 Dec 25;143(Pt 2):113470
Nppb contributes to Sepsis-Induced myocardial injury by regulating Senescence-Related genes.
Yang H, Jiang Z, Feng L, Wang C, Xu H, Wu X, Lin C, Zeng K
International immunopharmacology 2024 Dec 25;143(Pt 2):113461
International immunopharmacology 2024 Dec 25;143(Pt 2):113461
Preventive effects of matrine on LPS-induced inflammation in RAW 264.7 cells and intestinal damage in mice through the TLR4/NF-κB/MAPK pathway.
Mao N, Yu Y, Lu X, Yang Y, Liu Z, Wang D
International immunopharmacology 2024 Dec 25;143(Pt 2):113432
International immunopharmacology 2024 Dec 25;143(Pt 2):113432
Corilagin inhibits human cytomegalovirus infection and replication via activating the cGAS-STING signaling pathway in vitro and in vivo.
Xie J, Shang L, Liu C, Mao J, He C, Luo M, Fisher D, Thi Thu Hien N, Xu S, Zhao L
International immunopharmacology 2024 Dec 25;143(Pt 2):113401
International immunopharmacology 2024 Dec 25;143(Pt 2):113401
SHP-1 alleviates acute liver injury caused by Escherichia coli sepsis through negatively regulating the canonical and non-canonical NFκB signaling pathways.
Wang N, Tan S, Liu H, Wang M, Xia J, Zhang W, Wang M, Liu H, Sha Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113371
International immunopharmacology 2024 Dec 25;143(Pt 1):113371
Colorectal cancer cell-derived exosomal miRNA-372-5p induces immune escape from colorectal cancer via PTEN/AKT/NF-κB/PD-L1 pathway.
Wu Y, Xiao Y, Ding Y, Ran R, Wei K, Tao S, Mao H, Wang J, Pang S, Shi J, Zhu C, Wan W, Yang Q, Chen C
International immunopharmacology 2024 Dec 25;143(Pt 1):113261
International immunopharmacology 2024 Dec 25;143(Pt 1):113261
Chlorogenic acid alleviates IPEC-J2 pyroptosis induced by deoxynivalenol by inhibiting activation of the NF-κB/NLRP3/caspase-1 pathway.
Xue Y, Li F, Li R, Zhang X, Guo H, Wang C
Journal of animal science and biotechnology 2024 Dec 2;15(1):159
Journal of animal science and biotechnology 2024 Dec 2;15(1):159
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
Yang Q, Wan Q, Wang Z
Scientific reports 2024 Dec 2;14(1):29848
Scientific reports 2024 Dec 2;14(1):29848
EZH2 elicits CD8(+) T-cell desert in esophageal squamous cell carcinoma via suppressing CXCL9 and dendritic cells.
Zhu CY, Zhai TT, Su M, Pan HC, Tang Q, Huang BH, Chi XR, Li N, Xie LH, Qiu SQ, Pan F, Huang GW
Communications biology 2024 Dec 19;7(1):1645
Communications biology 2024 Dec 19;7(1):1645
17β-estradiol alleviated ferroptotic neuroinflammation by suppressing ATF4 in mouse model of Parkinson's disease.
Wang G, Zhuang W, Zhou Y, Wang X, Li Z, Liu C, Li W, He M, Lv E
Cell death discovery 2024 Dec 19;10(1):507
Cell death discovery 2024 Dec 19;10(1):507
HPV11 targeting KDM4A regulates the polarization of macrophage M(1) and promotes the development of nasal inverted papilloma.
Zheng L, Hu B, Yao W, Tian K, Zhu G, Jin M, Huang S, Chen X, Zhang Y
Cell communication and signaling : CCS 2024 Dec 18;22(1):603
Cell communication and signaling : CCS 2024 Dec 18;22(1):603
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Yu Y, Liu J, Zhao Z, Lan X, Li L, Hu J, Zang Y-a, Zhang X, Chen J
Journal of virology 2024 Dec 17;98(12):e0097424
Journal of virology 2024 Dec 17;98(12):e0097424
Soyasaponin Bb/Gelatin-Methacryloyl Hydrogel for Cartilage Inflammation Inhibition.
Jiang Y, Li T, Liu B, Tian Y, Wang Y, Li T, Zhang D
ACS omega 2024 Dec 17;9(50):49597-49608
ACS omega 2024 Dec 17;9(50):49597-49608
Inflammatory mediator contributes to leptin resistance and obesity in craniopharyngioma.
Xiao Y, Wu W, Liu F, Jin L, Jia Y, Qiao N, Cai K, Ru S, Cao L, Gui S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70242
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70242
Alantolactone improves cognitive impairment in rats with Porphyromonas gingivalis infection by inhibiting neuroinflammation, oxidative stress, and reducing Aβ levels.
Chen S, Han C, Wang X, Zhang Q, Yang X
Brain research 2024 Dec 15;1845:149203
Brain research 2024 Dec 15;1845:149203
NLRP3 blockade by MCC950 suppressed osteoclastogenesis via NF-κB/c-Fos/NFATc1 signal pathway and alleviated bone loss in diabetes mellitus.
Cai G, Song X, Luo H, Dai G, Zhang H, Jiang D, Lei X, Chen H, Zhang L
Molecular and cellular endocrinology 2024 Dec 1;594:112382
Molecular and cellular endocrinology 2024 Dec 1;594:112382
Pseudorabies virus VHS protein abrogates interferon responses by blocking NF-κB and IRF3 nuclear translocation.
Yan Z, Yue J, Zhang Y, Hou Z, Li D, Yang Y, Li X, Idris A, Li H, Li S, Xie J, Feng R
Virologica Sinica 2024 Aug;39(4):587-599
Virologica Sinica 2024 Aug;39(4):587-599
Silicone dressing combined with topical oxygen therapy alleviates incontinence-associated dermatitis via NF-κB p65/STAT1 signaling pathway.
Chen GA, Chen Y, Zhang Y, Zheng S, Zhu L, Ding M
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Aug;30(8):e13888
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Aug;30(8):e13888
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Xue W, Tianrun W, Jiaqi Y, Xin L, Ruxue D, Peng Z
Ecotoxicology and environmental safety 2024 Aug;281:116636
Ecotoxicology and environmental safety 2024 Aug;281:116636
M2 macrophages promote PD-L1 expression in triple-negative breast cancer via secreting CXCL1.
Zhang L, Gu S, Wang L, Zhao L, Li T, Zhao X, Zhang L
Pathology, research and practice 2024 Aug;260:155458
Pathology, research and practice 2024 Aug;260:155458
A p38 MAP kinase inhibitor suppresses osteoclastogenesis and alleviates ovariectomy-induced bone loss through the inhibition of bone turnover.
Xu C, Wei Z, Dong X, Xing J, Meng X, Qiu Y, Zhou H, Zheng W, Xu Z, Huang S, Xia W, Lv L, Jiang H, Wang W, Zhao X, Liu Z, Akimoto Y, Zhao B, Wang S, Hu Z
Biochemical pharmacology 2024 Aug;226:116391
Biochemical pharmacology 2024 Aug;226:116391
MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling.
Cai Y, Zhang Y, Wang S, Changyong E
Molecular immunology 2024 Aug;172:68-75
Molecular immunology 2024 Aug;172:68-75
Glycerol monolaurate regulates apoptosis and inflammation by suppressing lipopolysaccharide-induced ROS production and NF-κB activation in avian macrophages.
Kong L, Sun P, Pan X, Xiao C, Song B, Song Z
Poultry science 2024 Aug;103(8):103870
Poultry science 2024 Aug;103(8):103870
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Zhao W, Shen T, Zhao B, Li M, Deng Z, Huo Y, Aernouts B, Loor JJ, Psifidi A, Xu C
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Synergistic effects of plasma-activated medium in combination with Baicalin against neuronal damage.
Zhu J, Liu Q, Chen Y, Zhang J, Xu Q, Wu Z
Heliyon 2024 Aug 30;10(16):e36079
Heliyon 2024 Aug 30;10(16):e36079
Dihydromyricetin Nanoparticles Alleviate Lipopolysaccharide-Induced Acute Kidney Injury by Decreasing Inflammation and Cell Apoptosis via the TLR4/NF-κB Pathway.
Yin H, Yan Q, Li Y, Tang H
Journal of functional biomaterials 2024 Aug 29;15(9)
Journal of functional biomaterials 2024 Aug 29;15(9)
Tert promotes cardiac regenerative repair after MI through alleviating ROS-induced DNA damage response in cardiomyocyte.
Wei X, Zhou Y, Shao E, Shi X, Han Y, Zhang Y, Wei G, Zheng H, Huang S, Chen Y, Sun J, Liao Y, Liao W, Wang Y, Bin J, Li X
Cell death discovery 2024 Aug 26;10(1):381
Cell death discovery 2024 Aug 26;10(1):381
Adipose-derived stem cell exosomes loaded with icariin attenuated M1 polarization of macrophages via inhibiting the TLR4/Myd88/NF-κB signaling pathway.
Yan Q, Song C, Liu H, Li Y, Ma J, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z
International immunopharmacology 2024 Aug 20;137:112448
International immunopharmacology 2024 Aug 20;137:112448
Azithromycin regulates Mettl3-mediated NF-κB pathway to enhance M2 polarization of RAW264.7 macrophages and attenuate LPS-triggered cytotoxicity of MLE-12 alveolar cells.
Xu S, Xing J, Zheng L, Su H, Zou Y, Niu Y, Di H
International immunopharmacology 2024 Aug 20;137:112426
International immunopharmacology 2024 Aug 20;137:112426
Excitatory amino acid transporter supports inflammatory macrophage responses.
Gan Z, Guo Y, Zhao M, Ye Y, Liao Y, Liu B, Yin J, Zhou X, Yan Y, Yin Y, Ren W
Science bulletin 2024 Aug 15;69(15):2405-2419
Science bulletin 2024 Aug 15;69(15):2405-2419
Development of new dehydrocostuslactone derivatives for treatment of atopic dermatitis via inhibition of the NF-κB signaling pathway.
Li X, Lu C, Du W, Zou Q, Wang R, Hu C, Li Y, Zhang Y, Mao Z
RSC medicinal chemistry 2024 Aug 14;15(8):2773-2784
RSC medicinal chemistry 2024 Aug 14;15(8):2773-2784
Electroacupuncture Improving Intestinal Barrier Function in Rats with Irritable Bowel Syndrome Through Regulating Aquaporins.
Kang X, Zhang H, Li X, Zhang K, Huang Z, Li Y, Ren X, Chai Y
Digestive diseases and sciences 2024 Apr;69(4):1143-1155
Digestive diseases and sciences 2024 Apr;69(4):1143-1155
Sulforaphane inhibits the migration and invasion of BPDE-induced lung adenocarcinoma cells by regulating NLRP12.
Wang W, Chang S, He X, Zhou X, Shang P, Chen Y, Wang X, Chen L, Zhang Q, Qiao Y, Feng F
Toxicology and applied pharmacology 2024 Apr;485:116916
Toxicology and applied pharmacology 2024 Apr;485:116916
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Gao J, Zhou J, Zhang M, Zhang Y, Zeng Y, Li S, Xu K, Yao R
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Ganoderic acids alleviate atherosclerosis by inhibiting macrophage M1 polarization via TLR4/MyD88/NF-κB signaling pathway.
Quan YZ, Ma A, Ren CQ, An YP, Qiao PS, Gao C, Zhang YK, Li XW, Lin SM, Li NN, Chen DL, Pan Y, Zhou H, Lin DM, Lin SQ, Li M, Yang BX
Atherosclerosis 2024 Apr;391:117478
Atherosclerosis 2024 Apr;391:117478
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
Tan X, Wang J, Liu X, Xie G, Ouyang F
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
A TGF-β signaling-related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response.
Duan WW, Yang LT, Liu J, Dai ZY, Wang ZY, Zhang H, Zhang X, Liang XS, Luo P, Zhang J, Liu ZQ, Zhang N, Mo HY, Qu CR, Xia ZW, Cheng Q
CNS neuroscience & therapeutics 2024 Apr;30(4):e14489
CNS neuroscience & therapeutics 2024 Apr;30(4):e14489
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
Xiao G, Wei Y, Xie R, Tsang Y, Gu J, Shen D, Ding M, Yuan J, Xu D, Fei J
The FEBS journal 2024 Apr;291(8):1699-1718
The FEBS journal 2024 Apr;291(8):1699-1718
M2 macrophage‑derived exosomes alleviate KCa3.1 channel expression in rapidly paced HL‑1 myocytes via the NF‑κB (p65)/STAT3 signaling pathway.
Chen H, Liu H, Liu D, Fu Y, Yao Y, Cao Z, Peng Z, Yang M, Zhao Q
Molecular medicine reports 2024 Apr;29(4)
Molecular medicine reports 2024 Apr;29(4)
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Bao M, Li S, Zhu Y, Dong X, Wang R, Jing F
Experimental and therapeutic medicine 2024 Apr;27(4):165
Experimental and therapeutic medicine 2024 Apr;27(4):165
Purification, structural characterization, and immunomodulatory activity of two polysaccharides from Portulaca oleracea L.
Li Y, Ren M, Yan H, Luo L, Fang X, He L, Kang W, Wu M, Liu H
International journal of biological macromolecules 2024 Apr;264(Pt 1):130508
International journal of biological macromolecules 2024 Apr;264(Pt 1):130508
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.
Xu B, Cai X, Cai G, Huang G
Pathology, research and practice 2024 Apr;256:155233
Pathology, research and practice 2024 Apr;256:155233
Nucleoporin93 limits Yap activity to prevent endothelial cell senescence.
Nguyen TD, Rao MK, Dhyani SP, Banks JM, Winek MA, Michalkiewicz J, Lee MY
Aging cell 2024 Apr;23(4):e14095
Aging cell 2024 Apr;23(4):e14095
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Liu H, Zhou L, Wang X, Zheng Q, Zhan F, Zhou L, Dong Y, Xiong Y, Yi P, Xu G, Hua F
Biochemical pharmacology 2024 Apr;222:116050
Biochemical pharmacology 2024 Apr;222:116050
Icariin attenuates vascular endothelial dysfunction by inhibiting inflammation through GPER/Sirt1/HMGB1 signaling pathway in type 1 diabetic rats.
Yao W, Tao R, Wang K, Ding X
Chinese journal of natural medicines 2024 Apr;22(4):293-306
Chinese journal of natural medicines 2024 Apr;22(4):293-306
Osthole Activates the Cholinergic Anti-Inflammatory Pathway via α7nAChR Upregulation to Alleviate Inflammatory Responses.
Li SH, Li MY, Yuan TT, Wang GW, Zeng JB, Shi Z, Liu JH, Su JC
Chemistry & biodiversity 2024 Apr;21(4):e202400290
Chemistry & biodiversity 2024 Apr;21(4):e202400290
Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain.
Li Y, Yin C, Jiang J, Yang H, Zhang F, Xing Y, Wang W, Lu C
The international journal of biochemistry & cell biology 2024 Apr;169:106541
The international journal of biochemistry & cell biology 2024 Apr;169:106541
Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene.
Xu Y, Sun D, Xiong L, Zhang Z, Li Y, Liu K, Li H, Chen L
Bioorganic chemistry 2024 Apr;145:107190
Bioorganic chemistry 2024 Apr;145:107190
Single-cell transcriptomics reveals the ameliorative effect of rosmarinic acid on diabetic nephropathy-induced kidney injury by modulating oxidative stress and inflammation.
Chen J, Zhang Q, Guo J, Gu D, Liu J, Luo P, Bai Y, Chen J, Zhang X, Nie S, Chen C, Feng Y, Wang J
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1661-1676
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1661-1676
NF-κB affected the serum levels of TNF-α and IL-1β via activation of the MAPK/NF-κB signaling pathway in rat model of acute pulmonary microthromboembolism.
Zhong Y, Liang B, Zhang X, Li J, Zeng D, Huang T, Wu J
Pulmonary circulation 2024 Apr;14(2):e12357
Pulmonary circulation 2024 Apr;14(2):e12357
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer.
Tan P, Cai S, Huang Z, Li M, Liu S, Chen J, Fu W, Zhao L
Cellular signalling 2024 Apr;116:111033
Cellular signalling 2024 Apr;116:111033
Neonatal resveratrol administration promotes skeletal muscle growth and insulin sensitivity in intrauterine growth-retarded suckling piglets associated with activation of FGF21-AMPKα pathway.
Bai G, Chen J, Liu Y, Chen J, Yan H, You J, Zou T
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
Journal of the science of food and agriculture 2024 Apr;104(6):3719-3728
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
Li J, Feng C, Pang X, Li X, Dou X, Jiang E, Shang Z
Discover oncology 2024 Apr 8;15(1):109
Discover oncology 2024 Apr 8;15(1):109
A Flavonoid Glycoside Compound from Siraitia grosvenorii with Anti-Inflammatory and Hepatoprotective Effects In Vitro.
Wu J, Huang H, Gong L, Tian X, Peng Z, Zhu Y, Wang W
Biomolecules 2024 Apr 7;14(4)
Biomolecules 2024 Apr 7;14(4)
Mycobacterium tuberculosis PE_PGRS38 Enhances Intracellular Survival of Mycobacteria by Inhibiting TLR4/NF-κB-Dependent Inflammation and Apoptosis of the Host.
Ullah H, Shi X, Taj A, Cheng L, Yan Q, Sha S, Ahmad, Kang J, Haris M, Ma X, Ma Y
Biology 2024 Apr 30;13(5)
Biology 2024 Apr 30;13(5)
Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis.
Guo L, Yue M, Ma C, Wang Y, Hou J, Li H
Heliyon 2024 Apr 30;10(8):e29361
Heliyon 2024 Apr 30;10(8):e29361
Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.
Ding M, Zhu Y, Xu X, He H, Jiang T, Mo X, Wang Z, Yu W, Ou H
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7130-7139
Iridium(III)-Based PD-L1 Agonist Regulates p62 and ATF3 for Enhanced Cancer Immunotherapy.
Deng D, Wang M, Su Y, Fang H, Chen Y, Su Z
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Journal of medicinal chemistry 2024 Apr 25;67(8):6810-6821
Investigating the role of itaconate in macrophage activation and oxidative stress injury in sepsis-associated acute kidney injury.
Yang L, Zhou P, Li R, Yin Y, Xie G, Shi L, Zhang P, Tao K
Molecular biology reports 2024 Apr 20;51(1):533
Molecular biology reports 2024 Apr 20;51(1):533
Gypenoside XLIX alleviates acute liver injury: Emphasis on NF-κB/PPAR-α/NLRP3 pathways.
Zhou M, Cao Y, Xie S, Xiang Y, Li M, Yang H, Dong Z
International immunopharmacology 2024 Apr 20;131:111872
International immunopharmacology 2024 Apr 20;131:111872
6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway.
Yu Q, Li J, Cui M, Mei C, He Q, Du X
Scientific reports 2024 Apr 2;14(1):7747
Scientific reports 2024 Apr 2;14(1):7747
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
Wang R, Su D, Liu Y, Huang H, Qiu J, Cao Z, Yang G, Chen H, Luo W, Tao J, Weng G, Zhang T
iScience 2024 Apr 19;27(4):109406
iScience 2024 Apr 19;27(4):109406
Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway.
Wang Z, Dong Z, Li Y, Jiao X, Liu Y, Chang H, Gan Y
Biomedicines 2024 Apr 18;12(4)
Biomedicines 2024 Apr 18;12(4)
Phthalate exposure aggravates periodontitis by activating NFκB pathway.
Wu W, Jiang W, Zhou Y, Zhang Z, Li G, Tang C
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Ecotoxicology and environmental safety 2024 Apr 15;275:116252
Dietary Galacto-oligosaccharides Ameliorate Atopic Dermatitis-like Skin Inflammation and Behavioral Deficits by Modulating Gut Microbiota-Brain-Skin Axis.
Tang L, Cao X, Chen S, Jiang X, Li D, Chen G
Journal of agricultural and food chemistry 2024 Apr 10;72(14):7954-7968
Journal of agricultural and food chemistry 2024 Apr 10;72(14):7954-7968
Protective role of forsythoside B in Kawasaki disease-induced cardiac injury: Inhibition of pyroptosis via the SIRT1-NF-κB-p65 signaling pathway.
Yang Y, Wang N, Wang Z, Zhao M, Chen L, Shi Z
Chemico-biological interactions 2024 Apr 1;392:110953
Chemico-biological interactions 2024 Apr 1;392:110953
Phthalate drives splenic inflammatory response via activating HSP60/TLR4/NLRP3 signaling axis-dependent pyroptosis.
Ge XR, Zhao Y, Ren HR, Jiang FW, Liu S, Lou M, Huang YF, Chen MS, Wang JX, Li JL
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123610
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123610
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
MiR-181c-5p ameliorates learning and memory in sleep-deprived mice via HMGB1/TLR4/NF-κB pathway.
Hu Y, Hu C, Yin J, Zhong J, Deng Y, Yang G
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
Anais da Academia Brasileira de Ciencias 2023;95(suppl 1):e20220750
Herpetrione, a New Type of PPARα Ligand as a Therapeutic Strategy Against Nonalcoholic Steatohepatitis.
Linghu L, Zong W, Liao Y, Chen Q, Meng F, Wang G, Liao Z, Lan X, Chen M
Research (Washington, D.C.) 2023;6:0276
Research (Washington, D.C.) 2023;6:0276
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Pan Y, Liu Y
Allergologia et immunopathologia 2023;51(4):71-77
Allergologia et immunopathologia 2023;51(4):71-77
Triamcinolone acetonide induces the autophagy of Ag85B-treated WI-38 cells via SIRT1/FOXO3 pathway.
Luo L, Zhou L, Luo L, Feng D, Ding Y, Lu Z, Nie G, Bai L, Xiao Y
Allergologia et immunopathologia 2023;51(2):27-35
Allergologia et immunopathologia 2023;51(2):27-35
Protease-Activated Receptor-2 and Phospholipid Metabolism Analysis in Hyperuricemia-Induced Renal Injury.
Sui X, Xie T, Xu Y, Zhang A, Zhang Y, Gu F, Li L, Xu Z, Chen J
Mediators of inflammation 2023;2023:5007488
Mediators of inflammation 2023;2023:5007488
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
Wu H, Xiang Z, Huang G, He Q, Song J, Dou R, Yang C, Wang S, Xiong B
International journal of biological sciences 2023;19(2):465-483
International journal of biological sciences 2023;19(2):465-483
Rapamycin suppresses inflammation and increases the interaction between p65 and IκBα in rapamycin-induced fatty livers.
Ge C, Ma C, Cui J, Dong X, Sun L, Li Y, Yu A
PloS one 2023;18(3):e0281888
PloS one 2023;18(3):e0281888
Effect of matrine in MAC-T cells and their transcriptome analysis: A basic study.
Zhang Z, Yang Y, Yan L, Wan X, Sun K, Gou H, Ding J, Peng J, Liu G, Wang C
PloS one 2023;18(1):e0280905
PloS one 2023;18(1):e0280905
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Wang X, Yan X, Huang F, Wu L
Open life sciences 2023;18(1):20220679
Open life sciences 2023;18(1):20220679
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Zhang H, Zang C, Zhao W, Zhang L, Liu R, Feng Z, Wu J, Cui R
International journal of nanomedicine 2023;18:7047-7063
International journal of nanomedicine 2023;18:7047-7063
Ginseng Saponin Rb1 Attenuates Cigarette Smoke Exposure-Induced Inflammation, Apoptosis and Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Signaling Pathways.
Li Z, Li L, Lv X, Hu Y, Cui K
International journal of chronic obstructive pulmonary disease 2023;18:1883-1897
International journal of chronic obstructive pulmonary disease 2023;18:1883-1897
α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously.
Wu YJ, Zhang SS, Yin Q, Lei M, Wang QH, Chen WG, Luo TT, Zhou P, Ji CL
Drug design, development and therapy 2023;17:563-577
Drug design, development and therapy 2023;17:563-577
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88.
Luan C, Lu Z, Chen J, Chen M, Zhao R, Li X
Drug design, development and therapy 2023;17:2821-2839
Drug design, development and therapy 2023;17:2821-2839
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Li Y, Zhu S, Luo J, Tong Y, Zheng Y, Ji L, He Z, Jing Q, Huang J, Zhang Y, Bi Q
Drug design, development and therapy 2023;17:1515-1529
Drug design, development and therapy 2023;17:1515-1529
Icariin reduces cognitive dysfunction induced by surgical trauma in aged rats by inhibiting hippocampal neuroinflammation.
Wang L, Peng G, Chen L, Guo M, Wang B, Zhang Y, Zhou J, Zhong M, Ye J
Frontiers in behavioral neuroscience 2023;17:1162009
Frontiers in behavioral neuroscience 2023;17:1162009
A novel large animal model of posttraumatic osteoarthritis induced by inflammation with mechanical stability.
Sun C, Chang K, Fleming BC, Owens BD, Beveridge JE, Gage A, Talley-Bruns RC, McAllister S, Costa MQ, Pinette MP, Hague M, Molino J, Xiao Y, Lu S, Wei L
American journal of translational research 2023;15(7):4573-4586
American journal of translational research 2023;15(7):4573-4586
Shikimic acid (SA) inhibits neuro-inflammation and exerts neuroprotective effects in an LPS-induced in vitro and in vivo model.
Bao X, Zheng Z, Lv J, Bao J, Chang S, Jiang X, Xin Y
Frontiers in pharmacology 2023;14:1265571
Frontiers in pharmacology 2023;14:1265571
Ethyl acetate extract of Terminalia chebula alleviates DSS-induced ulcerative colitis in C57BL/6 mice.
Dong WR, Li YY, Liu TT, Zhou G, Chen YX
Frontiers in pharmacology 2023;14:1229772
Frontiers in pharmacology 2023;14:1229772
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) Nsp5 antagonizes type I interferon signaling by cleaving DCP1A.
Huang HX, Zhao CC, Lei XX, Zhang XY, Li YY, Lan T, Zhao BP, Lu JY, Sun WC, Lu HJ, Jin NY
Frontiers in immunology 2023;14:1196031
Frontiers in immunology 2023;14:1196031
Endothelial exosomes work as a functional mediator to activate macrophages.
Lin W, Huang F, Yuan Y, Li Q, Lin Z, Zhu W, Lin B, Zhu P
Frontiers in immunology 2023;14:1169471
Frontiers in immunology 2023;14:1169471
Human umbilical cord mesenchymal stem cells derived extracellular vesicles alleviate salpingitis by promoting M1-to-M2 transformation.
Zhang C, Liao W, Li W, Li M, Xu X, Sun H, Xue Y, Liu L, Qiu J, Zhang C, Zhang X, Ye J, Du J, Deng DYB, Deng W, Li T
Frontiers in physiology 2023;14:1131701
Frontiers in physiology 2023;14:1131701
Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats.
Zhang M, Cheng J, Luo J, Li C, Hou T, Zhao Y, Wang Y, Qu H, Kong H
Frontiers in pharmacology 2023;14:1118550
Frontiers in pharmacology 2023;14:1118550
The delta subunit of the GABA(A) receptor is necessary for the GPT2-promoted breast cancer metastasis.
Li N, Xu X, Liu D, Gao J, Gao Y, Wu X, Sheng H, Li Q, Mi J
Theranostics 2023;13(4):1355-1369
Theranostics 2023;13(4):1355-1369
Tumor-derived Immunoglobulin-like transcript 4 facilitates angiogenesis of colorectal cancer.
Liu J, Zhang F, He J, Wang S, Wang L, Li J, Shi W, Han Y, Gao A, Sun Y
American journal of cancer research 2023;13(2):419-435
American journal of cancer research 2023;13(2):419-435
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
You S, Zhu Y, Li H, He F, Liu S, Yang X, Wang L, Zeng H, Dai J, Hu L
Regenerative biomaterials 2023;10:rbad033
Regenerative biomaterials 2023;10:rbad033
Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation.
Nguyen TD, Rahman NT, Sessa WC, Lee MY
Frontiers in cardiovascular medicine 2023;10:1279868
Frontiers in cardiovascular medicine 2023;10:1279868
Blockade of C5aR1 alleviates liver inflammation and fibrosis in a mouse model of NASH by regulating TLR4 signaling and macrophage polarization.
Jiang K, Lu S, Li D, Liu M, Jin H, Lei B, Wang S, Long K, He S, Zhong F
Journal of gastroenterology 2023 Sep;58(9):894-907
Journal of gastroenterology 2023 Sep;58(9):894-907
Donor-Matched Peripheral Blood-Derived Mesenchymal Stem Cells Combined With Platelet-Rich Plasma Synergistically Ameliorate Surgery-Induced Osteoarthritis in Rabbits: An In Vitro and In Vivo Study.
Zhang K, Xu T, Xie H, Li J, Fu W
The American journal of sports medicine 2023 Sep;51(11):3008-3024
The American journal of sports medicine 2023 Sep;51(11):3008-3024
AKIP1 accelerates glioblastoma progression through stabilizing EGFR expression.
Wan S, Liu C, Li C, Wang Z, Zhao G, Li J, Ran W, Zhong X, Li Y, Zhang L, Cui H
Oncogene 2023 Sep;42(39):2905-2918
Oncogene 2023 Sep;42(39):2905-2918
ANRIL regulating the secretion of Muc5ac induced by atmospheric PM(2.5) via NF-κB pathway in Beas-2B cells.
Zhou L, Zhu Y, Zhang T, Zhang R, Liu Y, Li X, Zhao W, Ye J, Ju Y, Ye L
Environmental toxicology 2023 Sep;38(9):2256-2270
Environmental toxicology 2023 Sep;38(9):2256-2270
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Li T, Tang Q, Xu J, Ye X, Chen K, Zhong J, Zhu J, Lu S, Zhu T
Stem cells and development 2023 Sep;32(17-18):539-553
Stem cells and development 2023 Sep;32(17-18):539-553
The Chinese medicine Xin-tong-tai granule protects atherosclerosis by regulating oxidative stress through NOX/ROS/NF-κB signal pathway.
Wei JM, Yuan H, Liu CX, Wang ZY, Shi M, Guo ZH, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115200
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115200
Berberine protects cyclophosphamide and busulfan-induced premature ovarian insufficiency in mouse model.
Peng Y, Sun L, Guo W, Liu Z, Wang T, Zou T, Zhou J, Yang X, Fan X
Journal of pharmacological sciences 2023 Sep;153(1):46-54
Journal of pharmacological sciences 2023 Sep;153(1):46-54
Angiopoietin-2 Promotes Mechanical Stress-induced Extracellular Matrix Degradation in Annulus Fibrosus Via the HIF-1α/NF-κB Signaling Pathway.
Ao X, Li Y, Jiang T, Li C, Lian Z, Wang L, Zhang Z, Huang M
Orthopaedic surgery 2023 Sep;15(9):2410-2422
Orthopaedic surgery 2023 Sep;15(9):2410-2422
IL-38 suppresses macrophage M1 polarization to ameliorate synovial inflammation in the TMJ via GLUT-1 inhibition.
Luo P, Du M, Sun Q, Zhao T, He H
International immunopharmacology 2023 Sep;122:110619
International immunopharmacology 2023 Sep;122:110619
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Li Y, Li H, Wang L, Xie W, Yuan D, Wen Z, Zhang T, Lai J, Xiong Z, Shan Y, Jiang W
International immunopharmacology 2023 Sep;122:110518
International immunopharmacology 2023 Sep;122:110518
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Ning J, Pei Z, Wang M, Hu H, Chen M, Liu Q, Wu M, Yang P, Geng Z, Zheng J, Du Z, Hu W, Wang Q, Pang Y, Bao L, Niu Y, Leng S, Zhang R
Journal of hazardous materials 2023 Sep 5;457:131791
Journal of hazardous materials 2023 Sep 5;457:131791
Degenerated nucleus pulposus cells derived exosome carrying miR-27a-3p aggravates intervertebral disc degeneration by inducing M1 polarization of macrophages.
Zhao X, Sun Z, Xu B, Duan W, Chang L, Lai K, Ye Z
Journal of nanobiotechnology 2023 Sep 4;21(1):317
Journal of nanobiotechnology 2023 Sep 4;21(1):317
A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
Zhang L, Yang J, Liu W, Ding Q, Sun S, Zhang S, Wang N, Wang Y, Xi S, Liu C, Ding C, Li C
International journal of biological macromolecules 2023 Sep 30;249:126014
International journal of biological macromolecules 2023 Sep 30;249:126014
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
LINC00460 promotes angiogenesis by enhancing NF-κB-mediated VEGFA expression in cervical cancer cells.
Li F, Zhu W
Biochemical and biophysical research communications 2023 Sep 3;671:146-152
Biochemical and biophysical research communications 2023 Sep 3;671:146-152
The Gut Microbiota of Pregnant Rats Alleviates Fetal Growth Restriction by Inhibiting the TLR9/MyD88 Pathway.
Tang H, Li H, Li D, Peng J, Zhang X, Yang W
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Journal of microbiology and biotechnology 2023 Sep 28;33(9):1213-1227
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
Luo D, Liang Y, Wang Y, Ye F, Jin Y, Li Y, Han D, Wang Z, Chen B, Zhao W, Wang L, Chen X, Jiang L, Yang Q
Breast cancer research : BCR 2023 Sep 28;25(1):109
Breast cancer research : BCR 2023 Sep 28;25(1):109
Red Rice Seed Coat Targeting SPHK2 Ameliorated Alcoholic Liver Disease via Restored Intestinal Barrier and Improved Gut Microbiota in Mice.
Chen Y, Zhao Z, Guo S, Li Y, Yin H, Tian L, Cheng G, Li Y
Nutrients 2023 Sep 27;15(19)
Nutrients 2023 Sep 27;15(19)
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
Xie JR, Chen XJ, Zhou G
International journal of molecular sciences 2023 Sep 26;24(19)
International journal of molecular sciences 2023 Sep 26;24(19)
The Effects of an Osteoarthritic Joint Environment on ACL Damage and Degeneration: A Yucatan Miniature Pig Model.
Schwartz E, Chang K, Sun C, Zhang F, Peng G, Owens B, Wei L
Biomolecules 2023 Sep 20;13(9)
Biomolecules 2023 Sep 20;13(9)
Shiwei Qingwen decoction regulates TLR4/NF-κB signaling pathway and NLRP3 inflammasome to reduce inflammatory response in lipopolysaccharide-induced acute lung injury.
Zhang Q, Yang C, Ma S, Guo S, Hu X, Zhou Z, Liu Y, Zhang X, Jiang R, Zhang Z, Wen L
Journal of ethnopharmacology 2023 Sep 15;313:116615
Journal of ethnopharmacology 2023 Sep 15;313:116615
Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice.
Yao J, Liu J, He Y, Liu L, Xu Z, Lin X, Liu N, Kai G
Journal of ethnopharmacology 2023 Sep 15;313:116533
Journal of ethnopharmacology 2023 Sep 15;313:116533
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Zhou M, Barkema HW, Gao J, Yang J, Wang Y, Kastelic JP, Khan S, Liu G, Han B
Veterinary research 2023 Sep 14;54(1):78
Veterinary research 2023 Sep 14;54(1):78
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
Kong X, Zhao Y, Wang X, Yu Y, Meng Y, Yan G, Yu M, Jiang L, Song W, Wang B, Wang X
Chemico-biological interactions 2023 Sep 1;382:110640
Chemico-biological interactions 2023 Sep 1;382:110640
NR2C2 of macrophages promotes inflammation via NF-κB in LPS-induced orchitis in mice.
Min Z, Wan J, Xin H, Liu X, Rao X, Fan Z, Yang L, Li D
Reproduction (Cambridge, England) 2023 Sep 1;166(3):209-220
Reproduction (Cambridge, England) 2023 Sep 1;166(3):209-220
Decreasing REDD1 expression protects against high glucose-induced apoptosis, oxidative stress and inflammatory injury in podocytes through regulation of the AKT/GSK-3β/Nrf2 pathway.
Wang X, Yang J, Wang W, Li Y, Yang Y
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
Immunopharmacology and immunotoxicology 2023 Oct;45(5):527-538
SALL1 promotes proliferation and metastasis and activates phosphorylation of p65 and JUN in colorectal cancer cells.
Yuan J, Li G, Zhong F, Liao J, Zeng Z, Ouyang S, Xie H, Deng Z, Tang H, Ou X
Pathology, research and practice 2023 Oct;250:154827
Pathology, research and practice 2023 Oct;250:154827
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway.
Zhang Y, Peng X, Xue M, Liu J, Shang G, Jiang M, Chen D, Liu B, Wang Y, Jia X, Xu J, Zhang F, Hu Y
Biogerontology 2023 Oct;24(5):813-827
Biogerontology 2023 Oct;24(5):813-827
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Yin J, Hu T, Xu L, Zhang L, Zhu J, Ye Y, Pang Z
International immunopharmacology 2023 Oct;123:110763
International immunopharmacology 2023 Oct;123:110763
An in vitro and in vivo study: Valencene protects cartilage and alleviates the progression of osteoarthritis by anti-oxidative stress and anti-inflammatory effects.
Chen S, Meng C, He Y, Xu H, Qu Y, Wang Y, Fan Y, Huang X, You H
International immunopharmacology 2023 Oct;123:110726
International immunopharmacology 2023 Oct;123:110726
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155010
GSDMD promotes neutrophil extracellular traps via mtDNA-cGAS-STING pathway during lung ischemia/reperfusion.
Zhao C, Liang F, Ye M, Wu S, Qin Y, Zhao L, Zhang L, He J, Cen L, Lin F
Cell death discovery 2023 Oct 4;9(1):368
Cell death discovery 2023 Oct 4;9(1):368
IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10.
Yao W, Cui X, Peng H, Zhang Y, Jia X, Wu S, Zhao J
Cell death discovery 2023 Oct 31;9(1):403
Cell death discovery 2023 Oct 31;9(1):403
Epithelial-specific deletion of FAM20A leads to short root defects.
Liu L, Yao L, Lu Z, Jiang L, Zhang X, Liu X, Zhang W, Luan X, Zhang S, Xu W, Wang T, Zhang F, Wei X, Da J, Wang J, Zhang J, Li Y, Jin H, Zhang B
Gene 2023 Oct 30;884:147731
Gene 2023 Oct 30;884:147731
Scutellarin attenuates oxidative stress and neuroinflammation in cerebral ischemia/reperfusion injury through PI3K/Akt-mediated Nrf2 signaling pathways.
Xie X, Wang F, Ge W, Meng X, Fan L, Zhang W, Wang Z, Ding M, Gu S, Xing X, Sun X
European journal of pharmacology 2023 Oct 15;957:175979
European journal of pharmacology 2023 Oct 15;957:175979
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Yao R, Zhang Y, Zeng Y, Zhang Y, Liu L, Gao J
Experimental cell research 2023 Oct 1;431(1):113759
Experimental cell research 2023 Oct 1;431(1):113759
Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease.
Wang H, He D, Li Z, Gao X, Yang S, Cui M, Ye B, Huang B, Fu S, Liu D
Chemico-biological interactions 2023 Oct 1;384:110726
Chemico-biological interactions 2023 Oct 1;384:110726
The extract from Portulaca oleracea L. rehabilitates skin photoaging via adjusting miR-138-5p/Sirt1-mediated inflammation and oxidative stress.
Qu L, Wang F, Ma X
Heliyon 2023 Nov;9(11):e21955
Heliyon 2023 Nov;9(11):e21955
Arenobufagin increases the sensitivity of gastric cancer to cisplatin via alkaliptosis.
Liu C, Li D, Wang J, Wang Z
Heliyon 2023 Nov;9(11):e21110
Heliyon 2023 Nov;9(11):e21110
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
Xia W, Zhu Z, Xiang S, Yang Y
Journal of ginseng research 2023 Nov;47(6):784-794
Journal of ginseng research 2023 Nov;47(6):784-794
Mulberrin alleviates triclocarban induced hepatic apoptosis and inflammation by regulating the ROS/NF-κB pathway in grass carp.
Li S, Xie J, Li K, Bai Y, Jiang Z, Xiong X
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2023 Nov;273:109734
Nuciferine protects against lipopolysaccharide-induced endometritis via inhibiting ferroptosis and modulating AMPKα/mTOR/HIF-1α signaling axis.
Jiang P, Zhao L, Hu R, Zhai Z, Guo J, Zhang K
International immunopharmacology 2023 Nov;124(Pt B):110914
International immunopharmacology 2023 Nov;124(Pt B):110914
Pyroptosis of chondrocytes activated by synovial inflammation accelerates TMJ osteoarthritis cartilage degeneration via ROS/NLRP3 signaling.
Liu X, Li Y, Zhao J, Hu Z, Fang W, Ke J, Li W, Long X
International immunopharmacology 2023 Nov;124(Pt A):110781
International immunopharmacology 2023 Nov;124(Pt A):110781
Rabdosichuanin C inhibits productions of pro-inflammatory mediators regulated by NF-κB signaling in LPS-stimulated RAW264.7 cells.
Lingxia Z, Hong W, Man G, Xinzhou W, Lili W, Zhimin W, Liping D, Erping X
Journal of cellular biochemistry 2023 Nov;124(11):1667-1684
Journal of cellular biochemistry 2023 Nov;124(11):1667-1684
A Dihydroartemisinin-Loaded Nanoreactor Motivates Anti-Cancer Immunotherapy by Synergy-Induced Ferroptosis to Activate Cgas/STING for Reprogramming of Macrophage.
Li LG, Yang XX, Xu HZ, Yu TT, Li QR, Hu J, Peng XC, Han N, Xu X, Chen NN, Chen X, Tang JM, Li TF
Advanced healthcare materials 2023 Nov;12(28):e2301561
Advanced healthcare materials 2023 Nov;12(28):e2301561
A novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation.
An B, Nie W, Hu J, Fan Y, Nie H, Wang M, Zhao Y, Yao H, Ren Y, Zhang C, Wei M, Li W, Liu J, Yang C, Zhang Y, Li X, Tian G
Cell death & disease 2023 Nov 9;14(11):728
Cell death & disease 2023 Nov 9;14(11):728
Chromofungin, a chromogranin A-derived peptide, protects against sepsis-induced acute lung injury by inhibiting LBP/TLR4-dependent inflammatory signaling.
Zhou W, Kang S, Wang F, Qin Y, Liu J, Xiao X, Chen X, Zhang D
European journal of pharmacology 2023 Nov 5;958:176043
European journal of pharmacology 2023 Nov 5;958:176043
Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation.
Liu X, Li H, Feng Y, Guo H, Li Y, Ke J, Long X
Arthritis research & therapy 2023 Nov 29;25(1):230
Arthritis research & therapy 2023 Nov 29;25(1):230
Porcine promyelocytic leukemia protein isoforms suppress Japanese encephalitis virus replication in PK15 cells.
Chen Z, Liu H, Zhu J, Duan X, Wang H, Li X, Zhou X, Zhao A, Yang S
Virology journal 2023 Nov 29;20(1):280
Virology journal 2023 Nov 29;20(1):280
Network Analysis and Experimental Verification of the Mechanisms of Hydroxysafflor Yellow A in Ischemic Stroke Following Atherosclerosis.
Han X, Zhou H, Yin J, Zhu J, Yang J, Wan H
Molecules (Basel, Switzerland) 2023 Nov 28;28(23)
Molecules (Basel, Switzerland) 2023 Nov 28;28(23)
Gentiana Scabra Bge Extract (GSE) Protects Against Alcoholic Liver Disease by Regulating the TLR4/NF-κB Pathway in Mice.
Wang L, Jiang Y, Yu Q, Xiao C, Sun J, Weng L, Qiu Y
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):309
Frontiers in bioscience (Landmark edition) 2023 Nov 28;28(11):309
Salidroside Ameliorates Furan-Induced Testicular Inflammation in Relation to the Gut-Testis Axis and Intestinal Apoptosis.
Wang Z, Li L, Yan H, Li W, Pang Y, Yuan Y
Journal of agricultural and food chemistry 2023 Nov 22;71(46):17968-17987
Journal of agricultural and food chemistry 2023 Nov 22;71(46):17968-17987
Artemether Attenuates Gut Barrier Dysfunction and Intestinal Flora Imbalance in High-Fat and High-Fructose Diet-Fed Mice.
Ren X, Xu J, Xu Y, Wang Q, Huang K, He X
Nutrients 2023 Nov 21;15(23)
Nutrients 2023 Nov 21;15(23)
Nucleoporin93 (Nup93) Limits Yap Activity to Prevent Endothelial Cell Senescence.
Nguyen TD, Rao MK, Dhyani SP, Banks JM, Winek MA, Michalkiewicz J, Lee MY
bioRxiv : the preprint server for biology 2023 Nov 14;
bioRxiv : the preprint server for biology 2023 Nov 14;
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Wu M, Chen C, Lei H, Cao Z, Zhang C, Du R, Zhang C, Song Y, Qin M, Zhou J, Lu Y, Wang X, Zhang L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Fluoride-induced osteoporosis via interfering with the RANKL/RANK/OPG pathway in ovariectomized rats: Oophorectomy shifted skeletal fluorosis from osteosclerosis to osteoporosis.
Jin Y, Zhou BH, Zhao J, Ommati MM, Wang S, Wang HW
Environmental pollution (Barking, Essex : 1987) 2023 Nov 1;336:122407
Environmental pollution (Barking, Essex : 1987) 2023 Nov 1;336:122407
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
Zhou J, Xiang W, Zhang K, Zhao Q, Xu Z, Li Z
Neurochemical research 2023 May;48(5):1468-1479
Neurochemical research 2023 May;48(5):1468-1479
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Xi Y, Chi Z, Tao X, Zhai X, Zhao Z, Ren J, Yang S, Dong D
Environmental toxicology 2023 May;38(5):1153-1161
Environmental toxicology 2023 May;38(5):1153-1161
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma-aminobutyric acid (GABA)-ergic pathway and PI3K/AKT/NF-κB pathway.
Chen P, Huang NY, Pang B, Ye ZJ, Luo RX, Liu C, Gong Q, Wang C, Wang L
Phytotherapy research : PTR 2023 May;37(5):1883-1899
Phytotherapy research : PTR 2023 May;37(5):1883-1899
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer.
Júnior RFA, Lira GA, Schomann T, Cavalcante RS, Vilar NF, de Paula RCM, Gomes RF, Chung CK, Jorquera-Cordero C, Vepris O, Chan AB, Cruz LJ
Translational oncology 2023 May;31:101647
Translational oncology 2023 May;31:101647
Epstein-Barr virus envelope glycoprotein 110 inhibits NF-κB activation by interacting with NF-κB subunit p65.
Cai M, Xiao B, Wang Y, Wang K, Luo W, Fu J, Wang S, Deng S, Li B, Gong L, Zhong J, Hu L, Pan L, Wang L, Liu Y, Huang C, Li X, Zeng Q, Kang H, Li L, Zan J, Peng T, Yang H, Li M
The Journal of biological chemistry 2023 May;299(5):104613
The Journal of biological chemistry 2023 May;299(5):104613
Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats.
Wang L, Lei J, Zhao Z, Jia J, Wang L
Journal of veterinary science 2023 May;24(3):e23
Journal of veterinary science 2023 May;24(3):e23
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949
Environment international 2023 May;175:107949
Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.
Lu JH, Chueh KS, Juan TJ, Mao JW, Lin RJ, Lee YC, Shen MC, Sun TW, Lin HY, Juan YS
International journal of molecular sciences 2023 May 4;24(9)
International journal of molecular sciences 2023 May 4;24(9)
Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis.
Lian J, Zhu X, Du J, Huang B, Zhao F, Ma C, Guo R, Zhang Y, Ji L, Yahaya BH, Lin J
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1365-1382
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1365-1382
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis.
Shao D, Shen W, Miao Y, Gao Z, Pan M, Wei Q, Yan Z, Zhao X, Ma B
Journal of animal science and biotechnology 2023 May 3;14(1):61
Journal of animal science and biotechnology 2023 May 3;14(1):61
The potential role of the pseudobranch of molly fish (Poecilia sphenops) in immunity and cell regeneration.
Mokhtar DM, Sayed RKA, Zaccone G, Alesci A, Hussein MM
Scientific reports 2023 May 29;13(1):8665
Scientific reports 2023 May 29;13(1):8665
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Li W, Tao C, Mao M, Zhu K
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
Acta biochimica et biophysica Sinica 2023 May 26;55(5):818-830
Dahuang Zhechong pill attenuates hepatic sinusoidal capillarization in liver cirrhosis and hepatocellular carcinoma rat model via the MK/integrin signaling pathway.
Fu C, Zhang Y, Xi WJ, Xu K, Meng F, Ma T, Li W, Wu L, Chen Z
Journal of ethnopharmacology 2023 May 23;308:116191
Journal of ethnopharmacology 2023 May 23;308:116191
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Zhang ZH, Zhou XM, Zhang X
Brain sciences 2023 May 18;13(5)
Brain sciences 2023 May 18;13(5)
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Chen Y, Liu Y, Jiang K, Wen Z, Cao X, Wu S
Journal of orthopaedic translation 2023 Mar;39:1-11
Journal of orthopaedic translation 2023 Mar;39:1-11
FXYD3 enhances IL-17A signaling to promote psoriasis by competitively binding TRAF3 in keratinocytes.
Yang W, He R, Qu H, Lian W, Xue Y, Wang T, Lin W, Zhu P, Xia M, Lai L, Wang Q
Cellular & molecular immunology 2023 Mar;20(3):292-304
Cellular & molecular immunology 2023 Mar;20(3):292-304
Paeoniflorin alleviates inflammation in bovine mammary epithelial cells induced by Staphylococcus haemolyticus through TLR2/NF-κB signaling pathways.
Shen J, Yang F, Wang G, Mou X, Li J, Ding X, Wang X, Li H
Research in veterinary science 2023 Mar;156:95-103
Research in veterinary science 2023 Mar;156:95-103
The antimicrobial peptide LK2(6)A(L) exhibits anti-inflammatory activity by binding to the myeloid differentiation 2 domain and protects against LPS-induced acute lung injury in mice.
Zhang J, Sun Y, Sun C, Shang D
Bioorganic chemistry 2023 Mar;132:106376
Bioorganic chemistry 2023 Mar;132:106376
Onychiol B attenuates lipopolysaccharide-induced inflammation via MAPK/NF-κB pathways and acute lung injury in vivo.
Pei X, Zhang Z, Wang N, Huang G, Min X, Yang Y, Cao J
Bioorganic chemistry 2023 Mar;132:106351
Bioorganic chemistry 2023 Mar;132:106351
Meloxicam inhibited oxidative stress and inflammatory response of LPS-stimulated bovine endometrial epithelial cells through Nrf2 and NF-κB pathways.
Cui L, Guo J, Wang Z, Zhang J, Li W, Dong J, Liu K, Guo L, Li J, Wang H, Li J
International immunopharmacology 2023 Mar;116:109822
International immunopharmacology 2023 Mar;116:109822
pNaktide mitigates inflammation-induced neuronal damage and behavioral deficits through the oxidative stress pathway.
Zong Q, Pan Y, Liu Y, Wu Z, Huang Z, Zhang Y, Ma K
International immunopharmacology 2023 Mar;116:109727
International immunopharmacology 2023 Mar;116:109727
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
Sun K, Guo Z, Zhang J, Hou L, Liang S, Lu F, Wang G, Xu J, Zhang X, Guo F, Zhu W
Cell death discovery 2023 Mar 31;9(1):109
Cell death discovery 2023 Mar 31;9(1):109
Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy.
Gong W, Jiao Q, Yuan J, Luo H, Liu Y, Zhang Y, Chen Z, Xu X, Bai L, Zhang X
Clinical science (London, England : 1979) 2023 Mar 31;137(6):511-525
Clinical science (London, England : 1979) 2023 Mar 31;137(6):511-525
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Zhao L, Miao Y, Shan B, Zhao C, Peng C, Gong J
Foods (Basel, Switzerland) 2023 Mar 30;12(7)
Foods (Basel, Switzerland) 2023 Mar 30;12(7)
Improvement of vaginal probiotics Lactobacillus crispatus on intrauterine adhesion in mice model and in clinical practice.
Wu F, Kong Y, Chen W, Liang D, Xiao Q, Hu L, Tan X, Wei J, Liu Y, Deng X, Liu Z, Chen T
BMC microbiology 2023 Mar 22;23(1):78
BMC microbiology 2023 Mar 22;23(1):78
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Zhu X, Huang B, Zhao F, Lian J, He L, Zhang Y, Ji L, Zhang J, Yan X, Zeng T, Ma C, Liang Y, Zhang C, Lin J
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Nucleic acids research 2023 Mar 21;51(5):2195-2214
LINC01393, a Novel Long Non-Coding RNA, Promotes the Cell Proliferation, Migration and Invasion through MiR-128-3p/NUSAP1 Axis in Glioblastoma.
Li D, Hu J, Li S, Zhou C, Feng M, Li L, Gao Y, Chen X, Wu X, Cao Y, Hao B, Chen L
International journal of molecular sciences 2023 Mar 20;24(6)
International journal of molecular sciences 2023 Mar 20;24(6)
Selective Targeting of Class I HDAC Reduces Microglial Inflammation in the Entorhinal Cortex of Young APP/PS1 Mice.
Wang C, Shen D, Hu Y, Chen J, Liu J, Huang Y, Yu X, Chu H, Zhang C, Yin L, Liu Y, Ma H
International journal of molecular sciences 2023 Mar 2;24(5)
International journal of molecular sciences 2023 Mar 2;24(5)
Hypoxia-Induced Kidney Injury in Newborn Rats.
Chu YT, Chen BH, Chen HH, Lee JC, Kuo TJ, Chiu HC, Lu WH
Toxics 2023 Mar 11;11(3)
Toxics 2023 Mar 11;11(3)
Novel long non-coding RNAs associated with inflammation and macrophage activation in human.
Chini A, Guha P, Malladi VS, Guo Z, Mandal SS
Scientific reports 2023 Mar 10;13(1):4036
Scientific reports 2023 Mar 10;13(1):4036
PRKRA promotes pancreatic cancer progression by upregulating MMP1 transcription via the NF-κB pathway.
Qiu J, Feng M, Yang G, Su D, Zhao F, Liu Y, Tao J, Luo W, Zhang T
Heliyon 2023 Jun;9(6):e17194
Heliyon 2023 Jun;9(6):e17194
Remote preconditioning combined with nebulized budesonide alleviate lipopolysaccharide induced acute lung injury via regulating HO-1 and NF-κB in rats.
Zhao L, Chen Z, Cheng J, Chen B, Liu Y
Pulmonary pharmacology & therapeutics 2023 Jun;80:102215
Pulmonary pharmacology & therapeutics 2023 Jun;80:102215
1,25-Dihydroxvitamin D3 attenuates the damage of human immortalised keratinocytes caused by Ultraviolet-B.
Wang P, Liu D, Cui J, Yan S, Liang Y, Chen Q, Liu Y, Ren S, Chen P
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Cutaneous and ocular toxicology 2023 Jun;42(2):74-81
Up-regulation of ABCG2 by MYBL2 deletion drives Chlorin e6-mediated photodynamic therapy resistance in colorectal cancer.
Hui YJ, Chen H, Peng XC, Li LG, Di MJ, Liu H, Hu XH, Yang Y, Zhao KL, Li TF, Yu TT, Wang WX
Photodiagnosis and photodynamic therapy 2023 Jun;42:103558
Photodiagnosis and photodynamic therapy 2023 Jun;42:103558
Serum amyloid A and interleukin -1β facilitate LDL transcytosis across endothelial cells and atherosclerosis via NF-κB/caveolin-1/cavin-1 pathway.
Jia X, Liu Z, Wang Y, Li G, Bai X
Atherosclerosis 2023 Jun;375:87-97
Atherosclerosis 2023 Jun;375:87-97
Baicalin ameliorates high fat diet-induced nonalcoholic fatty liver disease in mice via adenosine monophosphate-activated protein kinase-mediated regulation of SREBP1/Nrf2/NF-κB signaling pathways.
Gao Y, Liu J, Hao Z, Sun N, Guo J, Zheng X, Sun P, Yin W, Fan K, Li H
Phytotherapy research : PTR 2023 Jun;37(6):2405-2418
Phytotherapy research : PTR 2023 Jun;37(6):2405-2418
Characterization of the Roles of Suppressor of Cytokine Signaling-3 in Esophageal Carcinoma.
Yang X, Tian M, Lin Y, Li L, Sun X, Zhang Z, Kang M, Lin J
Human gene therapy 2023 Jun;34(11-12):495-517
Human gene therapy 2023 Jun;34(11-12):495-517
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Ding H, Wang K, He LQ, Yang XY, Huang HH, Liu WL, Xiao C, Du ZX, Yu L, Zhang W
Journal of liposome research 2023 Jun;33(2):144-153
Journal of liposome research 2023 Jun;33(2):144-153
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Liu Z, Xiang H, Deng Q, Fu W, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Nephrology (Carlton, Vic.) 2023 Jun;28(6):315-327
Nephrology (Carlton, Vic.) 2023 Jun;28(6):315-327
Ent-kauranes and ent-atisanes from Euphorbia wallichii and their anti-inflammatory activity.
Wang Y, Jiang Q, Sun D, Zhang N, Lin Y, Li H, Chen L
Phytochemistry 2023 Jun;210:113643
Phytochemistry 2023 Jun;210:113643
TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection.
Wang J, Qin X, Huang Y, Zhang Q, Pei J, Wang Y, Goren I, Ma S, Song Z, Liu Y, Xing H, Wang H, Yang B
Autophagy 2023 Jun;19(6):1844-1862
Autophagy 2023 Jun;19(6):1844-1862
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Hepatocyte-derived extracellular vesicles miR-122-5p promotes hepatic ischemia reperfusion injury by regulating Kupffer cell polarization.
Liu L, Xiao F, Sun J, Wang Q, Wang A, Zhang F, Li Z, Wang X, Fang Z, Qiao Y
International immunopharmacology 2023 Jun;119:110060
International immunopharmacology 2023 Jun;119:110060
Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice.
Fu J, Yang J, He L, Yang C, He J, Hua Y, Guo J, Liu S
The Tohoku journal of experimental medicine 2023 Jun 7;260(2):149-163
The Tohoku journal of experimental medicine 2023 Jun 7;260(2):149-163
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Wu Y, Duan Z, Qu L, Zhang Y, Zhu C, Fan D
Food & function 2023 Jun 6;14(11):5167-5181
Food & function 2023 Jun 6;14(11):5167-5181
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
Ding Q, Ding C, Liu X, Zheng Y, Zhao Y, Zhang S, Sun S, Peng Z, Liu W
International journal of biological macromolecules 2023 Jun 30;241:124537
International journal of biological macromolecules 2023 Jun 30;241:124537
Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments.
Huang HT, Lv WQ, Xu FY, Wang XL, Yao YL, Su LJ, Zhao HJ, Huang Y
Medicine 2023 Jun 30;102(26):e34178
Medicine 2023 Jun 30;102(26):e34178
Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.
Guo C, Zhou X, Wang X, Wang H, Liu J, Wang J, Lin X, Lei S, Yang Y, Liu K, Long H, Zhou D
Journal of ethnopharmacology 2023 Jun 28;310:116298
Journal of ethnopharmacology 2023 Jun 28;310:116298
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Li P, Zhou D, Chen D, Cheng Y, Chen Y, Lin Z, Zhang X, Huang Z, Cai J, Huang W, Lin Y, Ke H, Long J, Zou Y, Ye S, Lan P
Journal of biomedical science 2023 Jun 28;30(1):47
Journal of biomedical science 2023 Jun 28;30(1):47
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Fei X, Huang J, Li F, Wang Y, Shao Z, Dong L, Wu Y, Li B, Zhang X, Lv B, Zhao Y, Weng Q, Chen K, Zhang M, Yang S, Zhang C, Zhang M, Li W, Ying S, Sun Q, Chen Z, Shen H
Cell reports 2023 Jun 27;42(6):112586
Cell reports 2023 Jun 27;42(6):112586
Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain.
Cheng Y, Dempsey RE, Roodsari SK, Shuboni-Mulligan DD, George O, Sanford LD, Guo ML
Biomedicines 2023 Jun 23;11(7)
Biomedicines 2023 Jun 23;11(7)
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
Cui Y, Zhang F, Xu W, Li Z, Zou J, Gao P, Hu J
BMC complementary medicine and therapies 2023 Jun 2;23(1):180
BMC complementary medicine and therapies 2023 Jun 2;23(1):180
Dysregulation of MiR-199a/IL8 pathway in chronic Cr (VI)-induced tumor growth and angiogenesis.
Wang L, Zhou ZH, Xie YX, Liu WJ, Zhang RX, Jiang N, He ML, Qiu JG, Jiang BH
Ecotoxicology and environmental safety 2023 Jun 19;262:115155
Ecotoxicology and environmental safety 2023 Jun 19;262:115155
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system.
Yuan T, Tang H, Xu X, Shao J, Wu G, Cho YC, Ping Y, Liang G
iScience 2023 Jun 16;26(6):106872
iScience 2023 Jun 16;26(6):106872
Epstein-Barr Virus Envelope Glycoprotein gp110 Inhibits IKKi-Mediated Activation of NF-κB and Promotes the Degradation of β-Catenin.
Guo Y, Pan L, Wang L, Wang S, Fu J, Luo W, Wang K, Li X, Huang C, Liu Y, Kang H, Zeng Q, Fu X, Huang Z, Li W, He Y, Li L, Peng T, Yang H, Li M, Xiao B, Cai M
Microbiology spectrum 2023 Jun 15;11(3):e0032623
Microbiology spectrum 2023 Jun 15;11(3):e0032623
SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy.
Yin J, Cai G, Wang H, Chen W, Liu S, Huang G
Cell division 2023 Jun 10;18(1):9
Cell division 2023 Jun 10;18(1):9
ATPIF1 alleviates oxygen glucose deprivation/reoxygenation-induced astrocyte injury in vitro: A rat model of ischemic brain injury.
Wei Z, Wu R, Zhang L, Xu P
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jul;32(7):791-802
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jul;32(7):791-802
Silicate ions as soluble form of bioactive ceramics alleviate aortic aneurysm and dissection.
Que Y, Zhang Z, Zhang Y, Li X, Chen L, Chen P, Ou C, Yang C, Chang J
Bioactive materials 2023 Jul;25:716-731
Bioactive materials 2023 Jul;25:716-731
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Wu B, Gan A, Wang R, Lin F, Yan T, Jia Y
Journal of chemical neuroanatomy 2023 Jul;130:102270
Journal of chemical neuroanatomy 2023 Jul;130:102270
Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis.
Chen J, He X, Bai Y, Liu J, Wong YK, Xie L, Zhang Q, Luo P, Gao P, Gu L, Guo Q, Cheng G, Wang C, Wang J
Journal of pharmaceutical analysis 2023 Jul;13(7):817-829
Journal of pharmaceutical analysis 2023 Jul;13(7):817-829
Dimethyl fumarate possesses antiplatelet and antithrombotic properties.
Chu X, Zhang J, Li Y, Yuan K, Wang X, Gui X, Sun Y, Geng C, Ju W, Xu M, Li Z, Zeng L, Xu K, Qiao J
International immunopharmacology 2023 Jul;120:110381
International immunopharmacology 2023 Jul;120:110381
Exenatide improves hypogonadism and attenuates inflammation in diabetic mice by modulating gut microbiota.
Chen Y, Shu A, Jiang M, Jiang J, Du Q, Chen T, Shaw C, Chai W, Chao T, Li X, Wu Q, Gao C
International immunopharmacology 2023 Jul;120:110339
International immunopharmacology 2023 Jul;120:110339
miR-9 targeting RUNX1 improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS.
Xiao C, Li Q, Xiao J, Chen X, Yuan J, Li S, Li W, Gao D, Li L, Liu Y, Shen F
International immunopharmacology 2023 Jul;120:110318
International immunopharmacology 2023 Jul;120:110318
Total saponins from Panax japonicus reduce inflammation in adipocytes through the miR155/SOCS1/NFκB signaling pathway.
Gao Y, Wang R, Li L, He Y, Yuan D, Zhang Y, Hu Y, Wang S, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154827
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154827
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Sun W, Wang Q, Zhang R, Zhang N
Food & function 2023 Jul 31;14(15):7247-7269
Food & function 2023 Jul 31;14(15):7247-7269
Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway.
Qi H, Shi H, Yan M, Zhao L, Yin Y, Tan X, Qi H, Li H, Weng K, Tang Y, Dai Y
Cell death discovery 2023 Jul 25;9(1):259
Cell death discovery 2023 Jul 25;9(1):259
Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats.
Yang X, Wang L, Zhang L, Zhai X, Sheng X, Quan H, Lin H
Diabetology & metabolic syndrome 2023 Jul 12;15(1):154
Diabetology & metabolic syndrome 2023 Jul 12;15(1):154
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Lin JP, Huang MH, Sun ZT, Chen L, Lei YH, Huang YQ, Qi M, Fan SR, Chen SG, Chung CW, Chan MC, Liu JS, Hu M, Chen MF, Ye WC, Chen YY, Deng LJ
Life sciences 2023 Jul 1;324:121715
Life sciences 2023 Jul 1;324:121715
DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation.
Lou M, Huang D, Zhou Z, Shi X, Wu M, Rui Y, Su J, Zheng W, Yu XF
Journal of medical virology 2023 Jan;95(1):e28310
Journal of medical virology 2023 Jan;95(1):e28310
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer.
Wang YF, Zhao LN, Geng Y, Yuan HF, Hou CY, Zhang HH, Yang G, Zhang XD
Acta pharmacologica Sinica 2023 Jan;44(1):211-220
Acta pharmacologica Sinica 2023 Jan;44(1):211-220
In vitro and in vivo effects of 3-indoleacetonitrile-A potential new broad-spectrum therapeutic agent for SARS-CoV-2 infection.
Hui X, Yu X, Huang K, Xu T, Cao L, Zhang Y, Zhao L, Zhao Y, Lv C, Feng S, Jiang Y, Liu L, Jin M
Antiviral research 2023 Jan;209:105465
Antiviral research 2023 Jan;209:105465
Diterpenoids with anti-inflammatory activity from Euphorbia wallichii.
Wang Y, Sun D, Jiang Q, Xiong L, Zhang N, Pan Y, Li H, Chen L
Phytochemistry 2023 Jan;205:113486
Phytochemistry 2023 Jan;205:113486
Koumine ameliorates concanavalin A-induced autoimmune hepatitis in mice: involvement of the Nrf2, NF-κB pathways, and gut microbiota.
Que W, Lin H, Li X, Zhang B, Liu M, Hu X, Fu J, Cheng Y, Qiu H
International immunopharmacology 2023 Jan;114:109573
International immunopharmacology 2023 Jan;114:109573
Structural and immunohistochemical analysis of the cellular compositions of the liver of molly fish (Poecilia sphenops), focusing on its immune role.
Hussein MM, Sayed RKA, Mokhtar DM
Zoological letters 2023 Jan 5;9(1):1
Zoological letters 2023 Jan 5;9(1):1
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Fan S, Weixuan W, Han H, Liansheng Z, Gang L, Jierui W, Yanshu Z
Chemico-biological interactions 2023 Jan 25;370:110310
Chemico-biological interactions 2023 Jan 25;370:110310
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
Chen H, Tu M, Liu S, Wen Y, Chen L
International journal of molecular sciences 2023 Jan 25;24(3)
International journal of molecular sciences 2023 Jan 25;24(3)
Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2.
Wu S, Tian X, Mao Q, Peng C
Clinical epigenetics 2023 Jan 23;15(1):12
Clinical epigenetics 2023 Jan 23;15(1):12
Microglial activation and over pruning involved in developmental epilepsy.
Wu Q, Wang H, Liu X, Zhao Y, Su P
Journal of neuropathology and experimental neurology 2023 Jan 20;82(2):150-159
Journal of neuropathology and experimental neurology 2023 Jan 20;82(2):150-159
CXCR3 Inhibition Blocks the NF-κB Signaling Pathway by Elevating Autophagy to Ameliorate Lipopolysaccharide-Induced Intestinal Dysfunction in Mice.
Zhang C, Deng Y, Zhang Y, Ba T, Niu S, Chen Y, Gao Y, Dai H
Cells 2023 Jan 1;12(1)
Cells 2023 Jan 1;12(1)
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways.
Huang L, Li Y, Cheng Z, Lv Z, Luo S, Xia Y
Inflammation 2023 Feb;46(1):115-128
Inflammation 2023 Feb;46(1):115-128
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Teng L, Shen Y, Qu Y, Yang L, Yang Y, Jian X, Fan S, Zhang L, Fu Q
Chinese journal of natural medicines 2023 Feb;21(2):99-112
Chinese journal of natural medicines 2023 Feb;21(2):99-112
Melatonin alleviates BDE-209-induced cognitive impairment and hippocampal neuroinflammation by modulating microglia polarization via SIRT1-mediated HMGB1/TLR4/NF-κB pathway.
Wu J, Hao Z, Wang Y, Yan D, Meng J, Ma H
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Feb;172:113561
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Feb;172:113561
α-Cyperone protects dopaminergic neurons and inhibits neuroinflammation in LPS-induced Parkinson's disease rat model via activating Nrf2/HO-1 and suppressing NF-κB signaling pathway.
Huang B, Hu G, Zong X, Yang S, He D, Gao X, Liu D
International immunopharmacology 2023 Feb;115:109698
International immunopharmacology 2023 Feb;115:109698
Iso-seco-tanapartholide induces p62 covalent oligomerization to activate KEAP1-NRF2 redox pathway in rheumatoid arthritis.
Zhu D, Kong M, Chen C, Luo J, Kong L
International immunopharmacology 2023 Feb;115:109689
International immunopharmacology 2023 Feb;115:109689
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways.
Wang X, Guo Z, Lin J, Sun K, Wang G, Hou L, Xu J, Guo J, Zhang X, Guo F, Wei Y
International immunopharmacology 2023 Feb;115:109624
International immunopharmacology 2023 Feb;115:109624
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
Trans-anethole exerts protective effects on lipopolysaccharide-induced acute jejunal inflammation of broilers via repressing NF-κB signaling pathway.
Tong Y, Yu C, Chen S, Zhang X, Yang Z, Wang T
Poultry science 2023 Feb;102(2):102397
Poultry science 2023 Feb;102(2):102397
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury.
Yang Y, Wang N, Xu L, Liu Y, Huang L, Gu M, Wu Y, Guo W, Sun H
Cell death & disease 2023 Feb 8;14(2):92
Cell death & disease 2023 Feb 8;14(2):92
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway.
Pang Y, Zhao L, Ji X, Guo K, Yin X
Molecules (Basel, Switzerland) 2023 Feb 7;28(4)
Molecules (Basel, Switzerland) 2023 Feb 7;28(4)
Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.
Wang J, Qin X, Huang Y, Zhang G, Liu Y, Cui Y, Wang Y, Pei J, Ma S, Song Z, Zhu X, Wang H, Yang B
Journal of virology 2023 Feb 28;97(2):e0197522
Journal of virology 2023 Feb 28;97(2):e0197522
A short peptide exerts neuroprotective effects on cerebral ischemia-reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis.
Li Y, Jin T, Liu N, Wang J, Qin Z, Yin S, Zhang Y, Fu Z, Wu Y, Wang Y, Liu Y, Yang M, Pang A, Sun J, Wang Y, Yang X
Journal of neuroinflammation 2023 Feb 28;20(1):53
Journal of neuroinflammation 2023 Feb 28;20(1):53
Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis.
Yang Q, He Y, Tian L, Zhang Z, Qiu L, Tao X, Wei H
Food & function 2023 Feb 21;14(4):2223-2238
Food & function 2023 Feb 21;14(4):2223-2238
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis.
Zhang L, Fang Z, Cheng G, He M, Lin Y
Cell death & disease 2023 Feb 20;14(2):145
Cell death & disease 2023 Feb 20;14(2):145
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Oxymatrine attenuated isoproterenol-induced heart failure via the TLR4/NF-κB and MAPK pathways in vivo and in vitro.
Sun H, Bai J, Sun Y, Zhen D, Fu D, Wang Y, Wei C
European journal of pharmacology 2023 Feb 15;941:175500
European journal of pharmacology 2023 Feb 15;941:175500
DBDPE upregulates NOD-like receptor signaling to induce NLRP3 inflammasome-mediated HAECs pyroptosis.
Jing L, Zheng D, Sun X, Shi Z
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120882
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120882
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
Sulforaphane Ameliorates Nonalcoholic Fatty Liver Disease Induced by High-Fat and High-Fructose Diet via LPS/TLR4 in the Gut-Liver Axis.
Xu Y, Huang X, Huangfu B, Hu Y, Xu J, Gao R, Huang K, He X
Nutrients 2023 Feb 1;15(3)
Nutrients 2023 Feb 1;15(3)
Auricular Vagus Nerve Stimulation Improves Visceral Hypersensitivity and Gastric Motility and Depression-like Behaviors via Vago-Vagal Pathway in a Rat Model of Functional Dyspepsia.
Hou L, Rong P, Yang Y, Fang J, Wang J, Wang Y, Zhang J, Zhang S, Zhang Z, Chen JDZ, Wei W
Brain sciences 2023 Feb 1;13(2)
Brain sciences 2023 Feb 1;13(2)
Phenylalanine diminishes M1 macrophage inflammation.
Zhang Q, Chen S, Guo Y, He F, Fu J, Ren W
Science China. Life sciences 2023 Dec;66(12):2862-2876
Science China. Life sciences 2023 Dec;66(12):2862-2876
Endogenous hydrogen sulfide inhibition suppresses tumor growth by promoting apoptosis and pyroptosis in esophageal cancer cells.
Wang HG, Wang D, Sarfraz M, Afzal A, Jing MR, Zhang YX, Cai CB, Qi HW, Chen HJ, Li T, Hu SJ, Liu HX, Ji XY, Wu DD
Translational oncology 2023 Dec;38:101770
Translational oncology 2023 Dec;38:101770
Electroacupuncture restores intestinal mucosal barrier through TLR4/NF-κB p65 pathway in functional dyspepsia-like rats.
Wang D, Zhang J, Yang D, Wang J, Li J, Han Y, Kang Z, Zhang H
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):2927-2938
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):2927-2938
The JAK/STAT/NF-κB signaling pathway can be regulated by rosemary essential oil, thereby providing a potential treatment for DNCB-induced in mice.
Li J, Duan J, Wang Y, Zhou P, Wang X, Xia N, Wang J, Li J, Wang W, Wang X, Sun J, Guo D, Zou J, Zhang X, Wang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115727
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115727
Catapol attenuates the aseptic inflammatory response to hepatic I/R injury in vivo and in vitro by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway via the microRNA-410-3p.
Feng ZJ, Wang LS, Ma X, Li K, Li XY, Tang Y, Peng CJ
Molecular immunology 2023 Dec;164:66-78
Molecular immunology 2023 Dec;164:66-78
L-F001, a multifunctional fasudil-lipoic acid dimer, antagonizes hypoxic-ischemic brain damage by inhibiting the TLR4/MyD88 signaling pathway.
Zhou R, Wu L, Jin N, Sha S, Ouyang Y
Brain and behavior 2023 Dec;13(12):e3280
Brain and behavior 2023 Dec;13(12):e3280
Umbelliferone attenuates cisplatin-induced acute kidney injury by inhibiting oxidative stress and inflammation via NRF2.
Yang Z, Ning R, Liu Q, Zang R, Liu S, Sun S
Physiological reports 2023 Dec;11(23):e15879
Physiological reports 2023 Dec;11(23):e15879
RNF144A promotes antiviral responses by modulating STING ubiquitination.
Yang B, Pei J, Lu C, Wang Y, Shen M, Qin X, Huang Y, Yang X, Zhao X, Ma S, Song Z, Liang Y, Wang H, Wang J
EMBO reports 2023 Dec 6;24(12):e57528
EMBO reports 2023 Dec 6;24(12):e57528
Piceatannol alleviates liver ischaemia/reperfusion injury by inhibiting TLR4/NF-κB/NLRP3 in hepatic macrophages.
Yao L, Cai H, Fang Q, Liu D, Zhan M, Chen L, Du J
European journal of pharmacology 2023 Dec 5;960:176149
European journal of pharmacology 2023 Dec 5;960:176149
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor.
Gao L, Zhao JX, Qin XM, Zhao J
Journal of ethnopharmacology 2023 Dec 5;317:116762
Journal of ethnopharmacology 2023 Dec 5;317:116762
Protective Effect of Ginsenoside CK against Autoimmune Hepatitis Induced by Concanavalin A.
Zhang J, Liu Y, An C, Liu C, Ma S, Zhang Q, Ding H, Shao J, Xue W
Foods (Basel, Switzerland) 2023 Dec 5;12(24)
Foods (Basel, Switzerland) 2023 Dec 5;12(24)
Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
Li C, Zhang Q, Huang W, Huang L, Long Q, Lei Y, Jia D, Yang S, Yang Y, Zhang X, Sun Q
Journal of medicinal chemistry 2023 Dec 28;66(24):17044-17058
Journal of medicinal chemistry 2023 Dec 28;66(24):17044-17058
Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway.
Luo F, Tang Y, Zheng L, Yang Y, Gao H, Tian S, Chen H, Tang C, Tang S, Man Q, Wu Y
Pharmaceuticals (Basel, Switzerland) 2023 Dec 27;17(1)
Pharmaceuticals (Basel, Switzerland) 2023 Dec 27;17(1)
Mesenchymal stem cell exosomes inhibit nucleus pulposus cell apoptosis via the miR-125b-5p/TRAF6/NF-κB pathway axis.
Duan Y, Yu C, Kuang W, Li J, Qiu S, Ni S, Chen Z
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
Acta biochimica et biophysica Sinica 2023 Dec 25;55(12):1938-1949
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease.
Cheng T, Agwu C, Shim K, Wang B, Jain S, Mahjoub MR
Development (Cambridge, England) 2023 Dec 15;150(24)
Development (Cambridge, England) 2023 Dec 15;150(24)
Lipopolysaccharide-induced persistent inflammation ameliorates fat accumulation by promoting adipose browning in vitro and in vivo.
Zhang W, Liu S, Kong L, Wu S, Zhong Z, Yu L, Yang Q, Zhang J, Li J, Zheng G
International journal of biological macromolecules 2023 Dec 1;252:126511
International journal of biological macromolecules 2023 Dec 1;252:126511
The outer membrane protein of Fusobacterium necrophorum, 43K OMP, stimulates inflammatory cytokine production through nuclear factor kappa B activation.
He X, Liu J, Jiang K, Lian S, Shi Y, Fu S, Zhao P, Xiao J, Sun D, Guo D
Anaerobe 2023 Aug;82:102768
Anaerobe 2023 Aug;82:102768
Overexpression of SERPINA3 suppresses tumor progression by modulating SPOP/NF‑κB in lung cancer.
Jin Y, Zhang Y, Huang A, Chen Y, Wang J, Liu N, Wang X, Gong Y, Wang W, Pan J
International journal of oncology 2023 Aug;63(2)
International journal of oncology 2023 Aug;63(2)
PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway.
Hu MD, Jia LH, Wang ML
Cell biology international 2023 Aug;47(8):1381-1391
Cell biology international 2023 Aug;47(8):1381-1391
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Zhang ZT, Deng SM, Chen C, He QH, Peng XW, Liang QF, Zhuang GD, Wang SM, Tang D
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Gu L, Wang F, Wang Y, Sun D, Sun Y, Tian T, Meng Q, Yin L, Xu L, Lu X, Peng J, Lin Y, Sun P
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Phytotherapy research : PTR 2023 Aug;37(8):3495-3507
Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.
Wang N, Jiang D, Zhou C, Han X
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Aug;32(8):909-920
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Aug;32(8):909-920
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Wang X, Zhou Y, Sun Q, Zhang Q, Zhou H, Zhang J, Du Y, Wang Y, Yuan K, Xu L, Zhang M, Yan D, Zeng L, Xu K, Sang W
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
Qin M, Lei H, Song Y, Wu M, Chen C, Cao Z, Zhang C, Du R, Zhang C, Wang X, Zhang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
ROR1/STAT3 positive feedback loop facilitates cartilage degeneration in Osteoarthritis through activation of NF-κB signaling pathway.
Huang W, Tang H, Liu Y, Li W, Shimu AS, Li B, Zhu C
International immunopharmacology 2023 Aug;121:110433
International immunopharmacology 2023 Aug;121:110433
Whey protein powder with milk fat globule membrane attenuates Alzheimer's disease pathology in 3×Tg-AD mice by modulating neuroinflammation through the peroxisome proliferator-activated receptor γ signaling pathway.
Li Y, Zhang ZH, Huang SL, Yue ZB, Yin XS, Feng ZQ, Zhang XG, Song GL
Journal of dairy science 2023 Aug;106(8):5253-5265
Journal of dairy science 2023 Aug;106(8):5253-5265
AGEs promote atherosclerosis by increasing LDL transcytosis across endothelial cells via RAGE/NF-κB/Caveolin-1 pathway.
Shu M, Cheng W, Jia X, Bai X, Zhao Y, Lu Y, Zhu L, Zhu Y, Wang L, Shu Y, Song Y, Jin S
Molecular medicine (Cambridge, Mass.) 2023 Aug 21;29(1):113
Molecular medicine (Cambridge, Mass.) 2023 Aug 21;29(1):113
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
Wang Z, Liu J, Li F, Ma S, Zhao L, Ge P, Wen H, Zhang Y, Liu X, Luo Y, Yao J, Zhang G, Chen H
Microbiology spectrum 2023 Aug 17;11(4):e0366422
Microbiology spectrum 2023 Aug 17;11(4):e0366422
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Salidroside alleviates acetaminophen-induced hepatotoxicity via Sirt1-mediated activation of Akt/Nrf2 pathway and suppression of NF-κB/NLRP3 inflammasome axis.
Gao Z, Zhan H, Zong W, Sun M, Linghu L, Wang G, Meng F, Chen M
Life sciences 2023 Aug 15;327:121793
Life sciences 2023 Aug 15;327:121793
Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling.
Huang X, Chen X, Li Q, Ni BH, Wang W
Toxicon : official journal of the International Society on Toxinology 2023 Aug 15;232:107202
Toxicon : official journal of the International Society on Toxinology 2023 Aug 15;232:107202
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530
Journal of ethnopharmacology 2023 Aug 10;312:116530
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin.
Huang H, Li X, Zha D, Lin H, Yang L, Wang Y, Xu L, Wang L, Lei T, Zhou Z, Xiao YF, Xin HB, Fu M, Qian Y
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Aug 1;101(4):303-312
Biochemistry and cell biology = Biochimie et biologie cellulaire 2023 Aug 1;101(4):303-312
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Zhao F, Ma T, Zhang X, Zhao Q, Zhu K, Cao J, Liu Z, Shen X, Li C
Molecular nutrition & food research 2023 Apr;67(8):e2200317
Molecular nutrition & food research 2023 Apr;67(8):e2200317
Atractylenolide III suppresses senescence-associated secretome via inhibiting cGAS/NF-κB pathway in hepatic stellate cells.
Wu H, Wu L, Xiao L, Gu Y, Liu H, Zhang L, Zhang M, Qi L
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Clinical and experimental pharmacology & physiology 2023 Apr;50(4):316-324
Asprosin Exacerbates Endothelium Inflammation Induced by Hyperlipidemia Through Activating IKKβ-NF-κBp65 Pathway.
Huang Q, Chen S, Xiong X, Yin T, Zhang Y, Zeng G, Huang Q
Inflammation 2023 Apr;46(2):623-638
Inflammation 2023 Apr;46(2):623-638
Protective effects of berberine against β-amyloid-induced neurotoxicity in HT22 cells via the Nrf2/HO-1 pathway.
Zhang RL, Lei BX, Wu GY, Wang YY, Huang QH
Bioorganic chemistry 2023 Apr;133:106210
Bioorganic chemistry 2023 Apr;133:106210
YY1 complex in M2 macrophage promotes prostate cancer progression by upregulating IL-6.
Chen S, Lu K, Hou Y, You Z, Shu C, Wei X, Wu T, Shi N, Zhang G, Wu J, Chen S, Zhang L, Li W, Zhang D, Ju S, Chen M, Xu B
Journal for immunotherapy of cancer 2023 Apr;11(4)
Journal for immunotherapy of cancer 2023 Apr;11(4)
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Zhang X, Yang X, Zhang S, Wang J, Wang M, Ma T, Wan M, Lv X, Yan T, Jia Y
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
The Journal of pharmacy and pharmacology 2023 Apr 7;75(4):574-584
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota.
Wei Y, Qi M, Liu C, Li L
European journal of pharmacology 2023 Apr 5;944:175594
European journal of pharmacology 2023 Apr 5;944:175594
Combined treatment with glucosamine and chondroitin sulfate improves rheumatoid arthritis in rats by regulating the gut microbiota.
Wang X, Liu D, Li D, Yan J, Yang J, Zhong X, Xu Q, Xu Y, Xia Y, Wang Q, Cao H, Zhang F
Nutrition & metabolism 2023 Apr 4;20(1):22
Nutrition & metabolism 2023 Apr 4;20(1):22
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)
Nutrients 2023 Apr 4;15(7)
Inhibition effect of 1-acetoxy-6α-(2-methylbutyryl)eriolanolide toward soluble epoxide hydrolase: Multispectral analysis, molecular dynamics simulation, biochemical, and in vitro cell-based studies.
Zhang J, Yang FY, Zhu QM, Zhang WH, Zhang M, Yi J, Wang Y, Zhang HL, Liang GB, Yan JK, Sun CP
International journal of biological macromolecules 2023 Apr 30;235:123911
International journal of biological macromolecules 2023 Apr 30;235:123911
Salvianolic Acid A Protects against Acetaminophen-Induced Hepatotoxicity via Regulation of the miR-485-3p/SIRT1 Pathway.
Tang F, Wang Z, Zhou J, Yao J
Antioxidants (Basel, Switzerland) 2023 Apr 3;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 3;12(4)
Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities.
Wang W, Liu Y, Xiong L, Sun D, Wang H, Song Z, Li Y, Li H, Chen L
Journal of natural products 2023 Apr 28;86(4):767-781
Journal of natural products 2023 Apr 28;86(4):767-781
YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis.
Fang Q, Tian GG, Wang Q, Liu M, He L, Li S, Wu J
Cell reports 2023 Apr 25;42(4):112403
Cell reports 2023 Apr 25;42(4):112403
Sea Cucumber Hydrolysate Alleviates Immunosuppression and Gut Microbiota Imbalance Induced by Cyclophosphamide in Balb/c Mice through the NF-κB Pathway.
Mao J, Li S, Fu R, Wang Y, Meng J, Jin Y, Wu T, Zhang M
Foods (Basel, Switzerland) 2023 Apr 10;12(8)
Foods (Basel, Switzerland) 2023 Apr 10;12(8)
Antibiotic Therapy and Vaginal Microbiota Transplantation Reduce Endometriosis Disease Progression in Female Mice via NF-κB Signaling Pathway.
Lu F, Wei J, Zhong Y, Feng Y, Ma B, Xiong Y, Wei K, Tan B, Chen T
Frontiers in medicine 2022;9:831115
Frontiers in medicine 2022;9:831115
Effect of Two Different Drug-Resistant Staphylococcus aureus Strains on the Physiological Properties of MAC-T Cells and Their Transcriptome Analysis.
Yan L, Yang Y, Ma X, Wei L, Wan X, Zhang Z, Ding J, Peng J, Liu G, Gou H, Wang C, Zhang X
Frontiers in veterinary science 2022;9:818928
Frontiers in veterinary science 2022;9:818928
Maternal nucleotide supplementation improves the intestinal morphology and immune function in lipopolysaccharide-challenged newborn piglets.
Li Q, Hung I, Bai K, Wang T
Frontiers in veterinary science 2022;9:1043842
Frontiers in veterinary science 2022;9:1043842
Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-[Formula: see text]B Signaling Pathway.
Huang ZW, Tan P, Yi XK, Chen H, Sun B, Shi H, Mou ZQ, Cheng YL, Li TX, Li Q, Fu WG
The American journal of Chinese medicine 2022;50(8):2185-2197
The American journal of Chinese medicine 2022;50(8):2185-2197
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway.
Chai Y, Jiao S, Peng X, Gan Q, Chen L, Hu X, Hao L, Zhang S, Tao Q
Pathology oncology research : POR 2022;28:1610273
Pathology oncology research : POR 2022;28:1610273
Guanxinping Tablets Inhibit ET-1-Induced Proliferation and Migration of MOVAS by Suppressing Activated PI3K/Akt/NF-κB Signaling Cascade.
Wu YY, Huang YL, Dai B, Liu JW, Han X
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9485463
Evidence-based complementary and alternative medicine : eCAM 2022;2022:9485463
The Attenuation of Chronic Ulcerative Colitis by (R)-salbutamol in Repeated DSS-Induced Mice.
Deng L, Guo H, Wang S, Liu X, Lin Y, Zhang R, Tan W
Oxidative medicine and cellular longevity 2022;2022:9318721
Oxidative medicine and cellular longevity 2022;2022:9318721
Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage.
Du D, Tang X, Li Y, Gao Y, Chen R, Chen Q, Wen J, Wu T, Zhang Y, Lu H, Zhang J, Wang S
Oxidative medicine and cellular longevity 2022;2022:9144644
Oxidative medicine and cellular longevity 2022;2022:9144644
Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways.
Liao Z, Su D, Liu H, Xu C, Wu J, Chen Y, Guo W, Zhang S, Li Z, Ke X, Wang T, Zhou T, Su P
Oxidative medicine and cellular longevity 2022;2022:8672969
Oxidative medicine and cellular longevity 2022;2022:8672969
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Gao Y, Hu M, Niu X, Li M, Xu L, Xiao Y, Zhang J, Wang H, Li L, Chu B, Lv P
Oxidative medicine and cellular longevity 2022;2022:8652741
Oxidative medicine and cellular longevity 2022;2022:8652741
ETC-1002 Attenuates Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells via the AMPK/NF-κB Pathway and Exerts Ameliorative Effects in Experimental Periodontitis in Mice.
Li H, Zhang P, Lin H, Gao H, Yin J
Disease markers 2022;2022:8583674
Disease markers 2022;2022:8583674
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Zhan L, Liu H, Zheng J, Meng J, Fu D, Pang L, Ji C
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6706622
Yanghe Pingchuan Granules Alleviate Airway Inflammation in Bronchial Asthma and Inhibit Pyroptosis by Blocking the TLR4/NF-κB/NRLP3 Signaling Pathway.
Pan L, Chen Y, Jiang Y, Sun Y, Han Y, Wang Y
Mediators of inflammation 2022;2022:6561048
Mediators of inflammation 2022;2022:6561048
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Tang R, Xiao G, Jian Y, Yuan Q, Jiang C, Wang W
Mediators of inflammation 2022;2022:6367264
Mediators of inflammation 2022;2022:6367264
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Zhang X, Wang S, Wang W, Song L, Feng S, Wang J, Kang T, Yang P, Wang N, Yang P, Bai R, Shao Y, Zheng Y
Mediators of inflammation 2022;2022:5978271
Mediators of inflammation 2022;2022:5978271
Effects of Electroacupuncture on Gastrointestinal Motility Function, Pain, and Inflammation via Transient Receptor Potential Vanilloid 1 in a Rat Model after Colonic Anastomoses.
Zhong X, Zhang Z, Li J, Liu D, Ma C, Wang G
Disease markers 2022;2022:5113473
Disease markers 2022;2022:5113473
Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway.
Lei Y, Chan M, Liu H, Lyu W, Chen L, Zhong Y, Gan H, Wang M, Qi M, Guo Y, Liu J, Zhang E
Disease markers 2022;2022:4399334
Disease markers 2022;2022:4399334
Curcumol Undermines SDF-1α/CXCR4/NF-κB Signaling Pathway to Suppress the Progression of Chronic Atrophic Gastritis (CAG) and Gastric Cancer.
Ma X, Kong L, Zhu W, Wang Y, Zhang Z, Tian Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3219001
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3219001
Electroacupuncture Pretreatment Exhibits Lung Protective and Anti-Inflammation Effects in Lipopolysaccharide-Induced Acute Lung Injury via SIRT1-Dependent Pathways.
Luo D, Liu L, Zhang HM, Zhou YD, Zhou MF, Li JX, Yu ZM, Tang Q, Yang SR, Chen R, Liang FX
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2252218
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2252218
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation of the Inflammatory Microenvironment.
Huang J, Lin J, Li C, Tang B, Xiao H
Stem cells international 2022;2022:1560943
Stem cells international 2022;2022:1560943
Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism.
Chen F, Qu F, Jia Y, Wang C, Yu Y, Liao J, Lin M, Chen F, Sun Z
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1240242
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1240242
BMAL1 regulates Propionibacterium acnes-induced skin inflammation via REV-ERBα in mice.
Li F, Lin L, He Y, Sun G, Dong D, Wu B
International journal of biological sciences 2022;18(6):2597-2608
International journal of biological sciences 2022;18(6):2597-2608
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
Zhao W, Zhang R, Zang C, Zhang L, Zhao R, Li Q, Yang Z, Feng Z, Zhang W, Cui R
International journal of nanomedicine 2022;17:4023-4038
International journal of nanomedicine 2022;17:4023-4038
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Rong ZJ, Cai HH, Wang H, Liu GH, Zhang ZW, Chen M, Huang YL
Frontiers in cellular neuroscience 2022;16:872935
Frontiers in cellular neuroscience 2022;16:872935
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
Liu J, Fan G, Tao N, Feng F, Meng C, Sun T
Drug design, development and therapy 2022;16:1793-1809
Drug design, development and therapy 2022;16:1793-1809
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558
Frontiers in molecular neuroscience 2022;15:859558
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promotes Diabetic Wound Healing via Regulating Angiogenesis, Inflammatory Response and Skin Flora.
Hao M, Ding C, Sun S, Peng X, Liu W
Journal of inflammation research 2022;15:4921-4938
Journal of inflammation research 2022;15:4921-4938
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Huang D, Wang P, Chen J, Li Y, Zhu M, Tang Y, Zhou W
Frontiers in immunology 2022;13:995791
Frontiers in immunology 2022;13:995791
Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65.
Hu H, Fu M, Li C, Zhang B, Li Y, Hu Q, Zhang M
Frontiers in immunology 2022;13:983502
Frontiers in immunology 2022;13:983502
Aconiti lateralis radix praeparata total alkaloids exert anti-RA effects by regulating NF-κB and JAK/STAT signaling pathways and promoting apoptosis.
Wu Y, Liu Y, Zhang L, Wen L, Xie Y
Frontiers in pharmacology 2022;13:980229
Frontiers in pharmacology 2022;13:980229
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Luo Q, Ling Y, Li Y, Qu X, Shi Q, Zheng S, Li Y, Huang Y, Zhou X
Frontiers in pharmacology 2022;13:964829
Frontiers in pharmacology 2022;13:964829
Novel recombinant protein flagellin A N/C attenuates experimental autoimmune encephalomyelitis by suppressing the ROS/NF-κB/NLRP3 signaling pathway.
Li L, Deng S, Liu M, Yang M, Li J, Liu T, Zhang T, Zhao Y, He M, Wu D, Xu Y
Frontiers in pharmacology 2022;13:956402
Frontiers in pharmacology 2022;13:956402
Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments.
Xu X, Li N, Wu Y, Yan K, Mi Y, Yi N, Tan X, Kuang G, Lu M
Frontiers in pharmacology 2022;13:951860
Frontiers in pharmacology 2022;13:951860
Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage.
Li LG, Peng XC, Yu TT, Xu HZ, Han N, Yang XX, Li QR, Hu J, Liu B, Yang ZY, Xu X, Chen X, Wang MF, Li TF
Frontiers in pharmacology 2022;13:949835
Frontiers in pharmacology 2022;13:949835
Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking.
Lu L, Peng J, Wan P, Peng H, Lu J, Xiong G
Frontiers in pharmacology 2022;13:940773
Frontiers in pharmacology 2022;13:940773
Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promoted Wound Healing by Regulating PI3K/AKT/mTOR and SIRT1/NF-κB Pathways.
Hao M, Peng X, Sun S, Ding C, Liu W
Frontiers in pharmacology 2022;13:913408
Frontiers in pharmacology 2022;13:913408
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Qu XQ, Chen QF, Shi QQ, Luo QQ, Zheng SY, Li YH, Bai LY, Gan S, Zhou XY
Frontiers in immunology 2022;13:901566
Frontiers in immunology 2022;13:901566
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Ling X, Zhou J, Jin T, Xu W, Sun X, Li W, Ding Y, Liang M, Zhu C, Zhao P, Hu C, Yuan B, Xie T, Tao J
Frontiers in pharmacology 2022;13:870928
Frontiers in pharmacology 2022;13:870928
MSC-ACE2 Ameliorates Streptococcus uberis-Induced Inflammatory Injury in Mammary Epithelial Cells by Upregulating the IL-10/STAT3/SOCS3 Pathway.
Yan S, Zhang C, Ji X, Wu G, Huang X, Zhang Y, Zhang Y
Frontiers in immunology 2022;13:870780
Frontiers in immunology 2022;13:870780
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Chen Y, Li T, Tan P, Shi H, Cheng Y, Cai T, Bai J, Du Y, Fu W
Frontiers in pharmacology 2022;13:857015
Frontiers in pharmacology 2022;13:857015
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Yu TT, Han N, Li LG, Peng XC, Li QR, Xu HZ, Wang XY, Yang ZY, Chen X, Wang MF, Li TF
Frontiers in pharmacology 2022;13:837784
Frontiers in pharmacology 2022;13:837784
Trans-Anethole Alleviates Subclinical Necro-Haemorrhagic Enteritis-Induced Intestinal Barrier Dysfunction and Intestinal Inflammation in Broilers.
Yu C, Wang D, Tong Y, Li Q, Yang W, Wang T, Yang Z
Frontiers in microbiology 2022;13:831882
Frontiers in microbiology 2022;13:831882
The Herb Pair Radix Rehmanniae and Cornus Officinalis Attenuated Testicular Damage in Mice With Diabetes Mellitus Through Butyric Acid/Glucagon-Like Peptide-1/Glucagon-Like Peptide-1 Receptor Pathway Mediated by Gut Microbiota.
Chen Y, Song S, Shu A, Liu L, Jiang J, Jiang M, Wu Q, Xu H, Sun J
Frontiers in microbiology 2022;13:831881
Frontiers in microbiology 2022;13:831881
Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control.
Yan M, Jin S, Liu Y, Wang L, Wang Z, Xia T, Chang Q
Frontiers in pharmacology 2022;13:824138
Frontiers in pharmacology 2022;13:824138
The Role of the Negative Regulation of Microglia-Mediated Neuroinflammation in Improving Emotional Behavior After Epileptic Seizures.
Wu Q, Wang H, Liu X, Zhao Y, Zhang J
Frontiers in neurology 2022;13:823908
Frontiers in neurology 2022;13:823908
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Plasma Exosomes Transfer miR-885-3p Targeting the AKT/NFκB Signaling Pathway to Improve the Sensitivity of Intravenous Glucocorticoid Therapy Against Graves Ophthalmopathy.
Sun J, Wei J, Zhang Y, Li J, Li J, Yan J, Guo M, Han J, Qiao H
Frontiers in immunology 2022;13:819680
Frontiers in immunology 2022;13:819680
Cordyceps militaris Modulates Intestinal Barrier Function and Gut Microbiota in a Pig Model.
Zheng H, Cao H, Zhang D, Huang J, Li J, Wang S, Lu J, Li X, Yang G, Shi X
Frontiers in microbiology 2022;13:810230
Frontiers in microbiology 2022;13:810230
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice.
Zhang KK, Chen LJ, Li JH, Liu JL, Wang LB, Xu LL, Yang JZ, Li XW, Xie XL, Wang Q
Frontiers in microbiology 2022;13:755189
Frontiers in microbiology 2022;13:755189
Inhibitory effect of main phenolic acid components of Jacobaea cannabifolia (Less.) on inflammation caused by PM(2.5).
Xu BL, Wang YY, Jiang LL, Liu Z, Liu DR, Zhao H, Li SL, Wang XB
Frontiers in pharmacology 2022;13:1096137
Frontiers in pharmacology 2022;13:1096137
Dynamic changes in human THP-1-derived M1-to-M2 macrophage polarization during Thelazia callipaeda MIF induction.
Yin C, Cai J, Gou Y, Li D, Tang H, Wang L, Liu H, Luo B
Frontiers in immunology 2022;13:1078880
Frontiers in immunology 2022;13:1078880
Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway.
Ma T, Jia L, Zhao J, Lv L, Yu Y, Ruan H, Song X, Chen H, Li X, Zhang J, Gao L
Frontiers in pharmacology 2022;13:1027553
Frontiers in pharmacology 2022;13:1027553
Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis.
Liao YF, Luo FL, Tang SS, Huang JW, Yang Y, Wang S, Jiang TY, Man Q, Liu S, Wu YY
Frontiers in pharmacology 2022;13:1014160
Frontiers in pharmacology 2022;13:1014160
Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus.
Wen Z, Zhang Y, Feng J, Aimulajiang K, Aleem MT, Lu M, Xu L, Song X, Li X, Yan R
Frontiers in immunology 2022;13:1013159
Frontiers in immunology 2022;13:1013159
Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway.
He J, Yang Y, Zhang F, Li Y, Li X, Pu X, He X, Zhang M, Yang X, Yu Q, Qi Y, Li X, Yu J
Frontiers in pharmacology 2022;13:1007274
Frontiers in pharmacology 2022;13:1007274
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Liu G, Wang Q, Deng L, Huang X, Yang G, Cheng Q, Guo T, Guo L, Niu C, Yang X, Dong J, Zhang J
Theranostics 2022;12(5):2248-2265
Theranostics 2022;12(5):2248-2265
Fusobacterium necrophorum Promotes Apoptosis and Inflammatory Cytokine Production Through the Activation of NF-κB and Death Receptor Signaling Pathways.
Wang FF, Zhao PY, He XJ, Jiang K, Wang TS, Xiao JW, Sun DB, Guo DH
Frontiers in cellular and infection microbiology 2022;12:827750
Frontiers in cellular and infection microbiology 2022;12:827750
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
Poloxamer 407 and Hyaluronic Acid Thermosensitive Hydrogel-Encapsulated Ginsenoside Rg3 to Promote Skin Wound Healing.
Peng X, Ding C, Zhao Y, Hao M, Liu W, Yang M, Xiao F, Zheng Y
Frontiers in bioengineering and biotechnology 2022;10:831007
Frontiers in bioengineering and biotechnology 2022;10:831007
HIV-1 Tat Protein-Mediated Inflammatory Response Inhibits the Erythroid Hematopoietic Support Function of Bone Marrow Mesenchymal Stem Cells.
Wang X, Chen M, Ma S, Ding Y, Zhou C, Yuan Y
AIDS research and human retroviruses 2022 Sep;38(9):753-763
AIDS research and human retroviruses 2022 Sep;38(9):753-763
Endoplasmic reticulum-targeted inhibition of CYP2E1 with vitamin E nanoemulsions alleviates hepatocyte oxidative stress and reverses alcoholic liver disease.
Shi Y, Liu Y, Wang S, Huang J, Luo Z, Jiang M, Lu Y, Lin Q, Liu H, Cheng N, You J
Biomaterials 2022 Sep;288:121720
Biomaterials 2022 Sep;288:121720
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Jiang T, Shen S, Wang L, Zhao M, Li Y, Huang S
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Applied biochemistry and biotechnology 2022 Sep;194(9):4093-4104
Hylocereus undatus flower extract suppresses OVA-induced allergic asthma in BALb/c mice by reducing airway inflammation and modulating gut microbiota.
Liao W, Liu W, Yan Y, Li L, Tong J, Huang Y, Guo S, Jiang W, Fu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113476
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113476
Protective effects of (R)-enantiomers but not (S)-enantiomers of β2-adrenergic receptor agonists against acute colitis: The role of β2AR.
Deng L, Wang S, Zhang R, Huang J, Lin Y, Liu X, Lu Z, Li M, Tan W
International immunopharmacology 2022 Sep;110:108997
International immunopharmacology 2022 Sep;110:108997
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Shen Y, Fan X, Qu Y, Tang M, Huang Y, Peng Y, Fu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154339
Targeting p65 to inhibit Cas3 transcription by Onjisaponin B for radiation damage therapy in p65+/- mice.
Wang TY, Hu YJ, Wang X, Li YF, Zhang F, Yan YD, Dou WT, Cheng CY, Xu P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154317
Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells.
Tong Y, Guo YJ, Zhang Q, Bi HX, Kai K, Zhou RY
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
Asian journal of andrology 2022 Sep-Oct;24(5):513-520
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
Sun W, Zhang N, Liu B, Yang J, Loers G, Siebert HC, Wen M, Zheng X, Wang Z, Han J, Zhang R
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
ACS chemical neuroscience 2022 Sep 7;13(17):2579-2598
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
Lycopene-Loaded Bilosomes Ameliorate High-Fat Diet-Induced Chronic Nephritis in Mice through the TLR4/MyD88 Inflammatory Pathway.
Liu C, Liu Y, Wang C, Guo Y, Cheng Y, Qian H, Zhao Y
Foods (Basel, Switzerland) 2022 Sep 30;11(19)
Foods (Basel, Switzerland) 2022 Sep 30;11(19)
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Rehman AU, Khan AI, Xin Y, Liang W
AMB Express 2022 Sep 3;12(1):114
AMB Express 2022 Sep 3;12(1):114
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
Zhu Z, Zhao Z, Chen X, Chu Z, He Y, Tan Y, Zhou J, Tang C
BMC molecular and cell biology 2022 Sep 29;23(1):42
BMC molecular and cell biology 2022 Sep 29;23(1):42
Isoalantolactone (IAL) Regulates Neuro-Inflammation and Neuronal Apoptosis to Curb Pathology of Parkinson's Disease.
He D, Liu Y, Li J, Wang H, Ye B, He Y, Li Z, Gao X, Fu S, Liu D
Cells 2022 Sep 19;11(18)
Cells 2022 Sep 19;11(18)
Isosteviol sodium attenuates high fat/high cholesterol-induced myocardial dysfunction by regulating the Sirt1/AMPK pathway.
Mei Y, Hu H, Deng L, Sun X, Tan W
Biochemical and biophysical research communications 2022 Sep 17;621:80-87
Biochemical and biophysical research communications 2022 Sep 17;621:80-87
LncRNA-SUSAJ1 Activates the ER Stress Pathway Inhibiting JEV Proliferation by Promoting PK15 Cells Apoptosis.
Yuan Q, Fan J, Wang H, Li X, Yang S, Zhao A, Zhou X
Frontiers in bioscience (Landmark edition) 2022 Sep 13;27(9):260
Frontiers in bioscience (Landmark edition) 2022 Sep 13;27(9):260
Pseudogene CLEC4GP1 modulates trophoblast cell apoptosis and invasion via IL-15 inhibition.
Yin A, Chen W, Tang L, Zhong M, Jia B
Experimental cell research 2022 Sep 1;418(1):113215
Experimental cell research 2022 Sep 1;418(1):113215
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Xu Z, Sun X, Ding B, Zi M, Ma Y
Transplant immunology 2022 Oct;74:101664
Transplant immunology 2022 Oct;74:101664
Impact of Resolvin D1 on the inflammatory phenotype of periodontal ligament cell response to hypoxia.
Cai J, Liu J, Yan J, Lu X, Wang X, Li S, Mustafa K, Wang H, Xue Y, Mustafa M, Kantarci A, Xing Z
Journal of periodontal research 2022 Oct;57(5):1034-1042
Journal of periodontal research 2022 Oct;57(5):1034-1042
Ulinastatin Alleviates Rhabdomyolysis-Induced Acute Kidney Injury by Suppressing Inflammation and Apoptosis via Inhibiting TLR4/NF-κB Signaling Pathway.
Wang J, Xu G, Jin H, Chai Y, Yang X, Liu Z, Hou S, Fan H
Inflammation 2022 Oct;45(5):2052-2065
Inflammation 2022 Oct;45(5):2052-2065
Network pharmacology and molecular docking study on the effect of Kaempferol in treatment of metabolic associated fatty liver disease.
Kaixuan Z, Dong Z, Huiwei B, Lijing LI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):788-794
Antihepatofibrotic effect of Guizhifuling pill on carbon tetrachloride-induced liver fibrosis in mice.
Baogui XU, Jiawen Z, Xiaoxiao T, Falei Y, Zhongliang L, Zuisu Y, Xianjun D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):715-722
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):715-722
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Ren X, Yu J, Guo L, Zhang Z
Metabolic brain disease 2022 Oct;37(7):2417-2429
Metabolic brain disease 2022 Oct;37(7):2417-2429
ALPK1 Accelerates the Pathogenesis of Osteoarthritis by Activating NLRP3 Signaling.
Liu X, Zhao J, Jiang H, Guo H, Li Y, Li H, Feng Y, Ke J, Long X
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 Oct;37(10):1973-1985
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 Oct;37(10):1973-1985
Curcumin antagonizes inflammation and autophagy induced by arsenic trioxide through immune protection in duck spleen.
Tang L, Lan J, Jiang X, Huang R, Pang Q, Wu S, Wan F, Zhong G, Tang Z, Hu L
Environmental science and pollution research international 2022 Oct;29(50):75344-75355
Environmental science and pollution research international 2022 Oct;29(50):75344-75355
mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification.
Fu J, Zhang J, Jiang T, Ao X, Li P, Lian Z, Li C, Zhang X, Liu J, Huang M, Zhang Z, Wang L
Bone 2022 Oct;163:116507
Bone 2022 Oct;163:116507
The anti-inflammatory effect of vasoactive peptides from soybean protein hydrolysates by mediating serum extracellular vesicles-derived miRNA-19b/CYLD/TRAF6 axis in the vascular microenvironment of SHRs.
Song T, Zhou M, Li W, Lv M, Zheng L, Zhao M
Food research international (Ottawa, Ont.) 2022 Oct;160:111742
Food research international (Ottawa, Ont.) 2022 Oct;160:111742
Achyranthes bidentata polysaccharides alleviate endoplasmic reticulum stress in osteoarthritis via lncRNA NEAT1/miR-377-3p pathway.
Fu C, Qiu Z, Huang Y, Lin Q, Jin L, Tu H, Ye J, Zheng C, Zhong W, Ma D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113551
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939
Bioorganic chemistry 2022 Oct;127:105939
Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway.
Fan G, Li Y, Liu Y, Suo X, Jia Y, Yang X
International immunopharmacology 2022 Oct;111:109171
International immunopharmacology 2022 Oct;111:109171
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
Qu Y, Shen Y, Teng L, Huang Y, Yang Y, Jian X, Fan S, Wu P, Fu Q
International immunopharmacology 2022 Oct;111:109129
International immunopharmacology 2022 Oct;111:109129
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Hao M, Ding C, Peng X, Chen H, Dong L, Zhang Y, Chen X, Liu W, Luo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154365
Endothelial RGS12 governs angiogenesis in inflammatory arthritis by controlling cilia formation and elongation via MYCBP2 signaling.
Yuan G, Yang ST, Yang S
Cell insight 2022 Oct;1(5):100055
Cell insight 2022 Oct;1(5):100055
Aspirin Inhibits the Inflammatory Response of Protease-Activated Receptor 1 in Pregnancy Neutrophils: Implications for Treating Women with Preeclampsia.
Walsh SW, Al Dulaimi M, Strauss JF 3rd
International journal of molecular sciences 2022 Oct 30;23(21)
International journal of molecular sciences 2022 Oct 30;23(21)
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
Chen T, Su S, Yang Z, Zhang D, Li Z, Lu D
Journal of ethnopharmacology 2022 Oct 28;297:115572
Journal of ethnopharmacology 2022 Oct 28;297:115572
L-Citrulline Supplementation Restrains Ferritinophagy-Mediated Ferroptosis to Alleviate Iron Overload-Induced Thymus Oxidative Damage and Immune Dysfunction.
Ba T, Zhao D, Chen Y, Zeng C, Zhang C, Niu S, Dai H
Nutrients 2022 Oct 28;14(21)
Nutrients 2022 Oct 28;14(21)
Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells.
Menon NG, Suhail Y, Goyal R, Du W, Tanguay AP, Jay GD, Ghosh M, Kshitiz, Schmidt TA
International journal of molecular sciences 2022 Oct 22;23(21)
International journal of molecular sciences 2022 Oct 22;23(21)
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation.
Zhang ZT, He WJ, Deng SM, Xu SH, Zeng X, Qian ZM, Chen ZQ, Wang SM, Tang D
European journal of pharmacology 2022 Oct 15;933:175291
European journal of pharmacology 2022 Oct 15;933:175291
SIRT5 alleviates hepatic ischemia and reperfusion injury by diminishing oxidative stress and inflammation via elevating SOD1 and IDH2 expression.
Zheng D, Qiwen Zeng, He D, He Y, Yang J
Experimental cell research 2022 Oct 15;419(2):113319
Experimental cell research 2022 Oct 15;419(2):113319
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Zhong X, Chen Z, Wang Y, Mao M, Deng Y, Shi M, Xu Y, Chen L, Cao W
Brain research bulletin 2022 Oct 15;189:174-183
Brain research bulletin 2022 Oct 15;189:174-183
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Cui C, Wu C, Wang J, Ma Z, Zheng X, Zhu P, Wang N, Zhu Y, Guan W, Chen F
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, Jayagopal A, Handa JT, Zigler JS Jr, Fort PE, Sodhi A, Sinha D
Nature communications 2022 Oct 13;13(1):6045
Nature communications 2022 Oct 13;13(1):6045
Effects of Exosomes Derived from Adipose-Derived Mesenchymal Stem Cells on Pyroptosis and Regeneration of Injured Liver.
Piao C, Sang J, Kou Z, Wang Y, Liu T, Lu X, Jiao Z, Wang H
International journal of molecular sciences 2022 Oct 11;23(20)
International journal of molecular sciences 2022 Oct 11;23(20)
RNA binding motif protein 3 (RBM3) promotes protein kinase B (AKT) activation to enhance glucose metabolism and reduce apoptosis in skeletal muscle of mice under acute cold exposure.
Liu Y, Shi H, Hu Y, Yao R, Liu P, Yang Y, Li S
Cell stress & chaperones 2022 Nov;27(6):603-618
Cell stress & chaperones 2022 Nov;27(6):603-618
P2X7 Receptor-Induced Bone Cancer Pain by Regulating Microglial Activity via NLRP3/IL-1beta Signaling.
Wu P, Wu X, Zhou G, Wang Y, Liu X, Lv R, Liu Y, Wen Q
Pain physician 2022 Nov;25(8):E1199-E1210
Pain physician 2022 Nov;25(8):E1199-E1210
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Zhan L, Zheng J, Meng J, Fu D, Pang L, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
CHRNA5 Is Overexpressed in Patients with Psoriasis and Promotes Psoriasis-Like Inflammation in Mouse Models.
Wang J, Li X, Zhang P, Yang T, Liu N, Qin L, Ma G, Li X, Fan H, Huang S, Dang N
The Journal of investigative dermatology 2022 Nov;142(11):2978-2987.e6
The Journal of investigative dermatology 2022 Nov;142(11):2978-2987.e6
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Wang N, Yang Y, Liu Y, Huang L, Gu M, Wu Y, Xu L, Sun H, Guo W
International immunopharmacology 2022 Nov;112:109242
International immunopharmacology 2022 Nov;112:109242
Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.
Zhao W, Xu D, Hong W, Zhang L, Wu Q, Gao M, Wang J
International immunopharmacology 2022 Nov;112:109190
International immunopharmacology 2022 Nov;112:109190
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Jin Y, Zhang Q, Qin X, Liu Z, Li Z, Zhong X, Xia L, He J, Fang B
Journal of nanobiotechnology 2022 Nov 3;20(1):469
Journal of nanobiotechnology 2022 Nov 3;20(1):469
In Vitro Anti-Influenza A Virus H1N1 Effect of Sesquiterpene-Rich Extracts of Carpesium abrotanoides.
Li L, Yang S, Chen D, Wu Z, Zhang M, Yang F, Qin L, Zhou X
Molecules (Basel, Switzerland) 2022 Nov 29;27(23)
Molecules (Basel, Switzerland) 2022 Nov 29;27(23)
The Role of Nuclear Factor-Kappa B in Fibrinogen-Induced Inflammatory Responses in Cultured Primary Neurons.
Sulimai N, Brown J, Lominadze D
Biomolecules 2022 Nov 23;12(12)
Biomolecules 2022 Nov 23;12(12)
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Purandare N, Kunji Y, Xi Y, Romero R, Gomez-Lopez N, Fribley A, Grossman LI, Aras S
iScience 2022 Nov 18;25(11):105342
iScience 2022 Nov 18;25(11):105342
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.
Zhou P, Lai J, Li Y, Deng J, Zhao C, Huang Q, Yang F, Yang S, Wu Y, Tang X, Huang F, Wang L, Huang X, Zou W, Wu J
International journal of molecular sciences 2022 Nov 14;23(22)
International journal of molecular sciences 2022 Nov 14;23(22)
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Liu Y, Kong X, You Y, Xiang L, Zhang Y, Wu R, Zhou L, Duan L
Cells 2022 Nov 12;11(22)
Cells 2022 Nov 12;11(22)
Altered Liver Metabolism, Mitochondrial Function, Oxidative Status, and Inflammatory Response in Intrauterine Growth Restriction Piglets with Different Growth Patterns before Weaning.
Wang J, Zhu P, Zheng X, Ma Z, Cui C, Wu C, Zeng X, Guan W, Chen F
Metabolites 2022 Nov 1;12(11)
Metabolites 2022 Nov 1;12(11)
Guhong injection promotes post-stroke functional recovery via attenuating cortical inflammation and apoptosis in subacute stage of ischemic stroke.
Wang Y, Wu H, Han Z, Sheng H, Wu Y, Wang Y, Guo X, Zhu Y, Li X, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154034
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154034
Antioxidant and Immunomodulatory Properties of Partially purified Exopolysaccharide from Lactobacillus Casei Isolated from Chinese Northeast Sauerkraut.
Xu X, Qiao Y, Peng Q, Shi B, Dia VP
Immunological investigations 2022 May;51(4):748-765
Immunological investigations 2022 May;51(4):748-765
TNFα-induced abnormal activation of TNFR/NF-κB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion.
Wen Y, Cheng M, Qin L, Xu W
Journal of cellular and molecular medicine 2022 May;26(10):2947-2958
Journal of cellular and molecular medicine 2022 May;26(10):2947-2958
Calpain-1 mediates vascular remodelling and fibrosis via HIF-1α in hypoxia-induced pulmonary hypertension.
Deng H, Tian X, Sun H, Liu H, Lu M, Wang H
Journal of cellular and molecular medicine 2022 May;26(10):2819-2830
Journal of cellular and molecular medicine 2022 May;26(10):2819-2830
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Yang L, Liu S, Yang L, Xu B, Wang M, Kong X, Song Z
Oncology letters 2022 May;23(5):162
Oncology letters 2022 May;23(5):162
PM(2.5) induced lung injury through upregulating ROS-dependent NLRP3 Inflammasome-Mediated Pyroptosis.
Ren F, Xu J, Zhang J, Xu X, Huang L, Sun W, Li R, Li F
Immunobiology 2022 May;227(3):152207
Immunobiology 2022 May;227(3):152207
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma.
Wang C, Liang H, Li Y, Tang Z, Zhang Y
Bioengineered 2022 May;13(5):12738-12748
Bioengineered 2022 May;13(5):12738-12748
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737
Bioorganic chemistry 2022 May;122:105737
SIRT3-AMPK signaling pathway as a protective target in endothelial dysfunction of early sepsis.
Yu H, Liu Q, Chen G, Huang L, Luo M, Lv D, Luo S
International immunopharmacology 2022 May;106:108600
International immunopharmacology 2022 May;106:108600
Transcriptomics combined with metabolomics analysis of the mechanism of agmatine in the treatment of septic liver injury.
Huang L, Gan L, Pan J, Zhong L, Wang Q, Luo S, Tian J, Liang H
Annals of translational medicine 2022 May;10(10):578
Annals of translational medicine 2022 May;10(10):578
Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model.
Chueh KS, Huang KH, Lu JH, Juan TJ, Chuang SM, Lin RJ, Lee YC, Long CY, Shen MC, Sun TW, Juan YS
International journal of molecular sciences 2022 May 21;23(10)
International journal of molecular sciences 2022 May 21;23(10)
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
Zhang X, Xie J, Gao M, Yan Z, Chen L, Wei S, Feng R
Viruses 2022 May 2;14(5)
Viruses 2022 May 2;14(5)
An Experimental Study Reveals the Protective Effect of Autophagy against Realgar-Induced Liver Injury via Suppressing ROS-Mediated NLRP3 Inflammasome Pathway.
Yang J, Li J, Guo H, Zhang Y, Guo Z, Liu Y, Huo T
International journal of molecular sciences 2022 May 19;23(10)
International journal of molecular sciences 2022 May 19;23(10)
Esculetin inhibits the pyroptosis of microvascular endothelial cells through NF-κB /NLRP3 signaling pathway.
Ren W, Zhou Q, Yu R, Liu Z, Hu Y
Archives of biochemistry and biophysics 2022 May 15;720:109173
Archives of biochemistry and biophysics 2022 May 15;720:109173
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Ren X, Xing Y, He L, Xiu Z, Yang L, Han A, Jia Q, Dong Y
Journal of ethnopharmacology 2022 May 10;289:115029
Journal of ethnopharmacology 2022 May 10;289:115029
Ameliorative effect of Gastrodia elata Blume extracts on depression in zebrafish and cellular models through modulating reticulon 4 receptors and apoptosis.
Wang R, Ren Q, Gao D, Paudel YN, Li X, Wang L, Zhang P, Wang B, Shang X, Jin M
Journal of ethnopharmacology 2022 May 10;289:115018
Journal of ethnopharmacology 2022 May 10;289:115018
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Xiong T, Zheng X, Zhang K, Wu H, Dong Y, Zhou F, Cheng B, Li L, Xu W, Su J, Huang J, Jiang Z, Li B, Zhang B, Lv G, Chen S
Journal of ethnopharmacology 2022 May 10;289:115001
Journal of ethnopharmacology 2022 May 10;289:115001
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Deng CY, Zhu TT, Lian S, Wang JF, Wu R, Zheng JS
Journal of veterinary research 2022 Mar;66(1):131-140
Journal of veterinary research 2022 Mar;66(1):131-140
Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway.
Li G, Duan L, Yang F, Yang L, Deng Y, Yu Y, Xu Y, Zhang Y
Phytotherapy research : PTR 2022 Mar;36(3):1326-1337
Phytotherapy research : PTR 2022 Mar;36(3):1326-1337
Costunolide protects against alcohol-induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro.
Mao J, Zhan H, Meng F, Wang G, Huang D, Liao Z, Chen M
Phytotherapy research : PTR 2022 Mar;36(3):1268-1283
Phytotherapy research : PTR 2022 Mar;36(3):1268-1283
CX-5461 is a potent immunosuppressant which inhibits T cell-mediated alloimmunity via p53-DUSP5.
Pan G, Zhang J, Han Y, Chen Y, Guo X, Cui X, Cheng M, Gao H, Wang J, Jiang F
Pharmacological research 2022 Mar;177:106120
Pharmacological research 2022 Mar;177:106120
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Li JJ, Liu ML, Lv JN, Chen RL, Ding K, He JQ
International immunopharmacology 2022 Mar;104:108510
International immunopharmacology 2022 Mar;104:108510
Transcriptional Regulation of RIP2 Gene by NFIB Is Associated with Cellular Immune and Inflammatory Response to APEC Infection.
Sun H, Li N, Tan J, Li H, Zhang J, Qu L, Lamont SJ
International journal of molecular sciences 2022 Mar 30;23(7)
International journal of molecular sciences 2022 Mar 30;23(7)
LINC01534/miR-135b-5p/PTPRT axis regulates inflammatory response in loosening total hip replacement via modulating NF-κB signaling pathway.
Zhang Y, Zhu Q, Fang Q, Yin D, Duan Y, Xue G, Ma N, Cai Y, He M
Injury 2022 Jun;53(6):1829-1836
Injury 2022 Jun;53(6):1829-1836
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Sclareol ameliorates hyperglycemia-induced renal injury through inhibiting the MAPK/NF-κB signaling pathway.
Han X, Zhang J, Zhou L, Wei J, Tu Y, Shi Q, Zhang Y, Ren J, Wang Y, Ying H, Liang G
Phytotherapy research : PTR 2022 Jun;36(6):2511-2523
Phytotherapy research : PTR 2022 Jun;36(6):2511-2523
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Li SN, Yu YL, Wang BY, Qiao SY, Hu MM, Wang H, Fu CN, Dong B
Human gene therapy 2022 Jun;33(11-12):598-613
Human gene therapy 2022 Jun;33(11-12):598-613
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
Blockade of mIL-6R alleviated lipopolysaccharide-induced systemic inflammatory response syndrome by suppressing NF-κB-mediated Ccl2 expression and inflammasome activation.
Dai JM, Zhang XQ, Zhang JJ, Yang WJ, Yang XM, Bian H, Chen ZN
MedComm 2022 Jun;3(2):e132
MedComm 2022 Jun;3(2):e132
Kaempferol prevents the activation of complement C3 protein and the generation of reactive A1 astrocytes that mediate rat brain degeneration induced by 3-nitropropionic acid.
Lopez-Sanchez C, Poejo J, Garcia-Lopez V, Salazar J, Garcia-Martinez V, Gutierrez-Merino C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113017
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113017
6-Gingerol exerts a protective effect against hypoxic injury through the p38/Nrf2/HO-1 and p38/NF-κB pathway in H9c2 cells.
Han X, Liu P, Zheng B, Zhang M, Zhang Y, Xue Y, Liu C, Chu X, Wang X, Sun S, Chu L
The Journal of nutritional biochemistry 2022 Jun;104:108975
The Journal of nutritional biochemistry 2022 Jun;104:108975
Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet.
Lin DT, Kao NJ, Cross TL, Lee WJ, Lin SH
The Journal of nutritional biochemistry 2022 Jun;104:108974
The Journal of nutritional biochemistry 2022 Jun;104:108974
Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway.
Qi L, Jiang J, Yu G, Zhang X, Qi X, Zhang J, Zhang L, Wang T
The Journal of nutritional biochemistry 2022 Jun;104:108973
The Journal of nutritional biochemistry 2022 Jun;104:108973
ISM1 suppresses LPS-induced acute lung injury and post-injury lung fibrosis in mice.
Nguyen N, Xu S, Lam TYW, Liao W, Wong WSF, Ge R
Molecular medicine (Cambridge, Mass.) 2022 Jun 25;28(1):72
Molecular medicine (Cambridge, Mass.) 2022 Jun 25;28(1):72
A nucleation barrier spring-loads the CBM signalosome for binary activation.
Rodriguez Gama A, Miller T, Lange JJ, Unruh JR, Halfmann R
eLife 2022 Jun 21;11
eLife 2022 Jun 21;11
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Chen H, Dong L, Chen X, Ding C, Hao M, Peng X, Zhang Y, Zhu H, Liu W
Experimental gerontology 2022 Jun 15;163:111769
Experimental gerontology 2022 Jun 15;163:111769
Long Non-coding RNA ANRIL Downregulation Alleviates Neuroinflammation in an Ischemia Stroke Model via Modulation of the miR-671-5p/NF-κB Pathway.
Deng L, Jiang J, Chen S, Lin X, Zuo T, Hu Q, Wu Y, Fan X, Dong Z
Neurochemical research 2022 Jul;47(7):2002-2015
Neurochemical research 2022 Jul;47(7):2002-2015
Effects of black tea and black brick tea with fungal growth on lowering uric acid levels in hyperuricemic mice.
Yuan D, Lin L, Peng Y, Zhou Y, Li L, Xiao W, Gong Z
Journal of food biochemistry 2022 Jul;46(7):e14140
Journal of food biochemistry 2022 Jul;46(7):e14140
Carnosol inhibits osteoclastogenesis in vivo and in vitro by blocking the RANKL‑induced NF‑κB signaling pathway.
Cai P, Yan S, Lu Y, Zhou X, Wang X, Wang M, Yin Z
Molecular medicine reports 2022 Jul;26(1)
Molecular medicine reports 2022 Jul;26(1)
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Liu Y, Sun R, Lin X, Wu L, Chen H, Shen S, Li Y, Wei Y, Deng G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113078
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jul;151:113078
TBK1 participates in glutaminolysis by mediating the phosphorylation of RIPK3 to promote endotoxin tolerance.
Pan L, Yang L, Yi Z, Zhang W, Gong J
Molecular immunology 2022 Jul;147:101-114
Molecular immunology 2022 Jul;147:101-114
Trans-anethole ameliorates LPS-induced inflammation via suppression of TLR4/NF-κB pathway in IEC-6 cells.
Yu C, Wang D, Li Q, Tong Y, Yang Z, Wang T
International immunopharmacology 2022 Jul;108:108872
International immunopharmacology 2022 Jul;108:108872
Eplerenone inhibits UUO-induced lymphangiogenesis and cardiac fibrosis by attenuating inflammatory injury.
Chen G, Chang Y, Xiong Y, Hao J, Liu L, Liu Z, Li H, Qiang P, Han Y, Xian Y, Shimosawa T, Wang X, Yang F, Xu Q
International immunopharmacology 2022 Jul;108:108759
International immunopharmacology 2022 Jul;108:108759
Pseudorabies Virus Tegument Protein UL13 Suppresses RLR-Mediated Antiviral Innate Immunity through Regulating Receptor Transcription.
Zhao N, Wang F, Kong Z, Shang Y
Viruses 2022 Jul 2;14(7)
Viruses 2022 Jul 2;14(7)
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Cai G, Ge Z, Xu Y, Cai L, Sun P, Huang G
Scientific reports 2022 Jul 16;12(1):12208
Scientific reports 2022 Jul 16;12(1):12208
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response.
Ma Y, Li S, Ye S, Hu D, Wei L, Xiao F
Ecotoxicology and environmental safety 2022 Jul 1;239:113645
Ecotoxicology and environmental safety 2022 Jul 1;239:113645
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Li X, Chu L, Liu S, Zhang W, Lin L, Zheng G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153728
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153728
Harmine is an effective therapeutic small molecule for the treatment of cardiac hypertrophy.
Huang J, Liu Y, Chen JX, Lu XY, Zhu WJ, Qin L, Xun ZX, Zheng QY, Li EM, Sun N, Xu C, Chen HY
Acta pharmacologica Sinica 2022 Jan;43(1):50-63
Acta pharmacologica Sinica 2022 Jan;43(1):50-63
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
Journal of clinical laboratory analysis 2022 Jan;36(1):e24019
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
Ghazisaeedi F, Meens J, Hansche B, Maurischat S, Schwerk P, Goethe R, Wieler LH, Fulde M, Tedin K
Gut microbes 2022 Jan-Dec;14(1):2106105
Gut microbes 2022 Jan-Dec;14(1):2106105
ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
Ma C, Liu M, Zhang J, Cai H, Wu Y, Zhang Y, Ji Y, Shan H, Zou Z, Yang L, Liu L, Xu H, Lei H, Liu C, Zhou L, Cao Y, Zhou H, Wu Y
Chemico-biological interactions 2022 Jan 5;351:109770
Chemico-biological interactions 2022 Jan 5;351:109770
Renoprotective activity of Ribes diacanthum pall (RDP) against inflammation in cisplatin-stimulated mice model and human renal tubular epithelial cells.
Wu Y, Zhao L, Gu L, Tilyek A, Yu B, Chai C
Journal of ethnopharmacology 2022 Jan 30;283:114696
Journal of ethnopharmacology 2022 Jan 30;283:114696
2-PMAP Ameliorates Cerebral Vasospasm and Brain Injury after Subarachnoid Hemorrhage by Regulating Neuro-Inflammation in Rats.
Wu CH, Tsai HP, Su YF, Tsai CY, Lu YY, Lin CL
Cells 2022 Jan 12;11(2)
Cells 2022 Jan 12;11(2)
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Zhang Y, Zhang X, Dai K, Zhu M, Liang Z, Pan J, Zhang Z, Xue R, Cao G, Hu X, Gong C
International journal of biological macromolecules 2022 Jan 1;194:223-232
International journal of biological macromolecules 2022 Jan 1;194:223-232
Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.
Chen Y, Qu L, Li Y, Chen C, He W, Shen L, Zhang R
Inflammation 2022 Feb;45(1):253-266
Inflammation 2022 Feb;45(1):253-266
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
Guo F, Cheng X, Jing B, Wu H, Jin X
Oncogene 2022 Feb;41(6):838-851
Oncogene 2022 Feb;41(6):838-851
Inhibition of high-fat diet-induced obesity via reduction of ER-resident protein Nogo occurs through multiple mechanisms.
Wang X, Yang Y, Zhao D, Zhang S, Chen Y, Chen Y, Feng K, Li X, Han J, Iwakiri Y, Duan Y, Yang X
The Journal of biological chemistry 2022 Feb;298(2):101561
The Journal of biological chemistry 2022 Feb;298(2):101561
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
Wei Z, Luo L, Hu S, Tian R, Liu Z
Experimental and therapeutic medicine 2022 Feb;23(2):154
Experimental and therapeutic medicine 2022 Feb;23(2):154
The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.
Shen Y, Yang R, Zhao J, Chen M, Chen S, Ji B, Chen H, Liu D, Li L, Du G
Pharmacological research 2022 Feb;176:105969
Pharmacological research 2022 Feb;176:105969
Pharmacological inhibition of TLR4-NF-κB signaling by TAK-242 attenuates hydrocephalus after intraventricular hemorrhage.
Lin T, Ding L, Lin Y, Liu C, Wang C, Wu D, Li Z, Li M, Sun J
International immunopharmacology 2022 Feb;103:108486
International immunopharmacology 2022 Feb;103:108486
18β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice.
Liu J, Xu Y, Yan M, Yu Y, Guo Y
Scientific reports 2022 Feb 24;12(1):3121
Scientific reports 2022 Feb 24;12(1):3121
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Wang Q, Wang C, Abdullah, Tian W, Qiu Z, Song M, Cao Y, Xiao J
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, Zhang Y, Hong X, Mao Y, He Q, Yang X, Liu N, Ma J
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
METTL3 overexpression aggravates LPS-induced cellular inflammation in mouse intestinal epithelial cells and DSS-induced IBD in mice.
Yang L, Wu G, Wu Q, Peng L, Yuan L
Cell death discovery 2022 Feb 14;8(1):62
Cell death discovery 2022 Feb 14;8(1):62
Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
Jyothula SSK, Peters A, Liang Y, Bi W, Shivshankar P, Yau S, Garcha PS, Yuan X, Akkanti B, Collum S, Wareing N, Thandavarayan RA, Poli de Frias F, Rosas IO, Zhao B, Buja LM, Eltzschig HK, Huang HJ, Karmouty-Quintana H
EBioMedicine 2022 Dec;86:104351
EBioMedicine 2022 Dec;86:104351
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Xia Y, Lu YW, Hao RJ, Yu GR
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Pharmaceutical biology 2022 Dec;60(1):2210-2218
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Tian J, Wang XL, Wang LC, Chen F, Tian Y, Ma L, Pan CY, Wang YP
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Holothuria Leucospilota polysaccharides alleviate hyperlipidemia via alteration of lipid metabolism and inflammation-related gene expression.
Lu S, Yuan Y, Chen F, Zheng Y, Li C, Cao J, Xia G, Liu Z, Shen X, He Y, Zhou D, Zhu K
Journal of food biochemistry 2022 Dec;46(12):e14392
Journal of food biochemistry 2022 Dec;46(12):e14392
Chymotrypsin attenuates adjuvant-induced arthritis by downregulating TLR4, NF-κB, MMP-1, TNF-α, IL-1β, and IL-6 expression in Sprague-Dawley rats.
Li J, Wang L, Zeng G, Li H, Luo J, Tian Q, Zhang Z
Immunopharmacology and immunotoxicology 2022 Dec;44(6):959-969
Immunopharmacology and immunotoxicology 2022 Dec;44(6):959-969
Resveratrol inhibits the progression of premature senescence partially by regulating v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) and sirtuin 1 (SIRT1).
He S, Zhou M, Zheng H, Wang Y, Wu S, Gao Y, Chen J
Renal failure 2022 Dec;44(1):171-183
Renal failure 2022 Dec;44(1):171-183
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Yu R, Hou C, Peng Y, Zhu X, Shi C, Huang D, Miao Y, Li Q
Molecular immunology 2022 Dec;152:55-66
Molecular immunology 2022 Dec;152:55-66
1,25(OH)(2)D(3) alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway.
Ma Y, Yang Y, Lv M, Zhang Y, He Q, Zhang Y, Su H, Deng X, Qian Y
Placenta 2022 Dec;130:34-41
Placenta 2022 Dec;130:34-41
Biotransformation of 18β-Glycyrrhetinic Acid by Human Intestinal Fungus Aspergillus niger RG13B1 and the Potential Anti-Inflammatory Mechanism of Its Metabolites.
Zhang M, Zhang J, Wang C, Yan JK, Yi J, Ning J, Huo XK, Yu ZL, Zhang BJ, Sun CP, Ma XC
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15104-15115
GABA regulates IL-1β production in macrophages.
Fu J, Han Z, Wu Z, Xia Y, Yang G, Yin Y, Ren W
Cell reports 2022 Dec 6;41(10):111770
Cell reports 2022 Dec 6;41(10):111770
A Regulatory Loop Involving miR-200c and NF-κB Modulates Mortalin Expression and Increases Cisplatin Sensitivity in an Ovarian Cancer Cell Line Model.
Huang X, Yan Y, Gui A, Zhu S, Qiu S, Chen F, Liu W, Zuo J, Yang L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
FGF5 protects heart from sepsis injury by attenuating cardiomyocyte pyroptosis through inhibiting CaMKII/NFκB signaling.
Cui S, Li Y, Zhang X, Wu B, Li M, Gao J, Xia H, Xu L
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):104-112
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 2):104-112
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells.
Wang J, Li G, Lin M, Lin S, Wu L
BMC molecular and cell biology 2022 Dec 23;23(1):60
BMC molecular and cell biology 2022 Dec 23;23(1):60
Aerobic exercise improves intestinal mucosal barrier dysfunction through TLR4/MyD88/NF-κB signaling pathway in diabetic rats.
Li J, Liu X, Wu Y, Ji W, Tian Q, Li S
Biochemical and biophysical research communications 2022 Dec 17;634:75-82
Biochemical and biophysical research communications 2022 Dec 17;634:75-82
Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways.
Zhang B, Wei X, Ding M, Luo Z, Tan X, Zheng Z
Molecules (Basel, Switzerland) 2022 Dec 15;27(24)
Molecules (Basel, Switzerland) 2022 Dec 15;27(24)
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Long noncoding RNA GAS5 alleviates the inflammatory response of human periodontal ligament stem cells by regulating the NF-κB signalling pathway.
Yang Q, Liu P, Han Y, Wang C, Huang Y, Li X, Zheng Y, Li W
European journal of orthodontics 2022 Dec 1;44(6):669-678
European journal of orthodontics 2022 Dec 1;44(6):669-678
Low-dose arsenite causes overexpression of EGF, TGFα, and HSP90 through Trx1-TXNIP-NLRP3 axis mediated signaling pathways in the human bladder epithelial cells.
Jin P, Zhou Q, Xi S
Ecotoxicology and environmental safety 2022 Dec 1;247:114263
Ecotoxicology and environmental safety 2022 Dec 1;247:114263
Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide.
Li Y, Zhang H, Tu F, Cao J, Hou X, Chen Y, Yan J
Journal of animal science 2022 Dec 1;100(12)
Journal of animal science 2022 Dec 1;100(12)
MELK predicts poor prognosis and promotes metastasis in esophageal squamous cell carcinoma via activating the NF‑κB pathway.
Ye J, Deng W, Zhong Y, Liu H, Guo B, Qin Z, Li P, Zhong X, Wang L
International journal of oncology 2022 Aug;61(2)
International journal of oncology 2022 Aug;61(2)
Administration of krill oil extends lifespan of fish Nothobranchius guentheri via enhancement of antioxidant system and suppression of NF-κB pathway.
Song L, Leng K, Xiao K, Zhang S
Fish physiology and biochemistry 2022 Aug;48(4):1057-1073
Fish physiology and biochemistry 2022 Aug;48(4):1057-1073
Annexin-1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin-8.
Chen R, Chen C, Han N, Guo W, Deng H, Wang Y, Ding Y, Zhang M
Journal of cellular and molecular medicine 2022 Aug;26(15):4343-4356
Journal of cellular and molecular medicine 2022 Aug;26(15):4343-4356
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Ding Q, Chen K, Liu X, Ding C, Zhao Y, Sun S, Zhang Y, Zhang J, Liu S, Liu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Aug;152:113242
Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma.
Koizume S, Takahashi T, Nakamura Y, Yoshihara M, Ota Y, Sato S, Tadokoro H, Yokose T, Kato H, Miyagi E, Miyagi Y
British journal of cancer 2022 Aug;127(3):462-473
British journal of cancer 2022 Aug;127(3):462-473
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
Xiu T, Guo Q, Jing F, Shi Y, Jing F
Translational cancer research 2022 Aug;11(8):2487-2500
Translational cancer research 2022 Aug;11(8):2487-2500
Trans-anethole ameliorates lipopolysaccharide-induced acute liver inflammation in broilers via inhibiting NF-κB signaling pathway.
Tong Y, Yu C, Xie Z, Zhang X, Yang Z, Wang T
Poultry science 2022 Aug;101(8):101962
Poultry science 2022 Aug;101(8):101962
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Cui J, Zong W, Zhao N, Yuan R
Food science & nutrition 2022 Aug;10(8):2718-2726
Food science & nutrition 2022 Aug;10(8):2718-2726
Harm of circadian misalignment to the hearts of the adolescent wistar rats.
Wang Y, Hou Y, Song S, Zuo Y, Yu Y, Chi Y, Zhang T
Journal of translational medicine 2022 Aug 6;20(1):352
Journal of translational medicine 2022 Aug 6;20(1):352
Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways.
Xu Z, Hao X, Li M, Luo H
International journal of molecular sciences 2022 Aug 28;23(17)
International journal of molecular sciences 2022 Aug 28;23(17)
Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies.
Wu D, Wang Z, Zhang J, Robinson AG, Lyu B, Chen Z, Wang C, Wei B, Xia X, Zhang Q, Zhou X
Cell death & disease 2022 Aug 24;13(8):731
Cell death & disease 2022 Aug 24;13(8):731
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
Hou W, Lu L, Li X, Sun M, Zhu M, Miao C
Cellular signalling 2022 Apr;92:110263
Cellular signalling 2022 Apr;92:110263
Metadherin silencing results in the inhibition of pyroptosis in lipopolysaccharide/adenosine triphosphate - stimulated renal tubular epithelial cells.
Duan X, Song Y, Li F, Liao Y, Liu W
Tissue & cell 2022 Apr;75:101722
Tissue & cell 2022 Apr;75:101722
Enzyme-instructed self-assembly of peptide-drug conjugates in tear fluids for ocular drug delivery.
Hu Y, Wang Y, Deng J, Ding X, Lin D, Shi H, Chen L, Lin D, Wang Y, Vakal S, Wang J, Li X
Journal of controlled release : official journal of the Controlled Release Society 2022 Apr;344:261-271
Journal of controlled release : official journal of the Controlled Release Society 2022 Apr;344:261-271
Andrographolide Inhibits Proliferation and Promotes Apoptosis in Bladder Cancer Cells by Interfering with NF- κ B and PI3K/AKT Signaling In Vitro and In Vivo.
Xuan L, Hu JH, Bi R, Liu SQ, Wang CX
Chinese journal of integrative medicine 2022 Apr;28(4):349-356
Chinese journal of integrative medicine 2022 Apr;28(4):349-356
Mechanism exploration of ancient pharmaceutic processing (Paozhi) improving the gastroprotective efficacy of Aucklandiae Radix.
Song S, Qiu R, Jin X, Zhou Z, Yan J, Ou Q, Liu X, Li W, Mao Y, Yao W, Lu T
Journal of ethnopharmacology 2022 Apr 6;287:114911
Journal of ethnopharmacology 2022 Apr 6;287:114911
Platycodon grandiflorum root fermentation broth reduces inflammation in a mouse IBD model through the AMPK/NF-κB/NLRP3 pathway.
Wang Z, Li C, He X, Xu K, Xue Z, Wang T, Xu Z, Liu X
Food & function 2022 Apr 4;13(7):3946-3956
Food & function 2022 Apr 4;13(7):3946-3956
PRMT5 critically mediates TMAO-induced inflammatory response in vascular smooth muscle cells.
Liu H, Jia K, Ren Z, Sun J, Pan LL
Cell death & disease 2022 Apr 4;13(4):299
Cell death & disease 2022 Apr 4;13(4):299
Preventive effects of the AMPA receptor potentiator LY450108 in an LPS-induced depressive mouse model.
Yao H, Guo W, Suo L, Li G, Wang Y, Chen Y, Sun Y, Ding R
Behavioural brain research 2022 Apr 29;424:113813
Behavioural brain research 2022 Apr 29;424:113813
Human Norovirus Induces Aquaporin 1 Production by Activating NF-κB Signaling Pathway.
Zhang M, Zhang B, Chen R, Li M, Zheng Z, Xu W, Zhang Y, Gong S, Hu Q
Viruses 2022 Apr 18;14(4)
Viruses 2022 Apr 18;14(4)
Curcumin activates the Nrf2 Pathway to alleviate AFB1-induced immunosuppression in the spleen of ducklings.
Wan F, Tang L, Rao G, Zhong G, Jiang X, Wu S, Huang R, Tang Z, Ruan Z, Chen Z, Hu L
Toxicon : official journal of the International Society on Toxinology 2022 Apr 15;209:18-27
Toxicon : official journal of the International Society on Toxinology 2022 Apr 15;209:18-27
A novel promoter-associated non-coding small RNA paGLI1 recruits FUS/P65 to transactivate GLI1 gene expression and promotes infiltrating glioma progression.
Zhong J, Xu M, Su Z, Zhang M, Yu T, Nie L, Gong J, Chen X, Chen N, Zhou Q
Cancer letters 2022 Apr 1;530:68-84
Cancer letters 2022 Apr 1;530:68-84
miR-142a-3p Enhances FlaA N/C Protection Against Radiation-Mediated Intestinal Injury by Modulating the IRAK1/NF-κB Signaling Pathway.
Liu T, Wu DM, Zhang F, Zhang T, He M, Zhao YY, Li J, Li L, Xu Y
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1256-1268
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1256-1268
Therapeutic effect of and mechanisms underlying the effect of miR-195-5p on subarachnoid hemorrhage-induced vasospasm and brain injury in rats.
Tsai TH, Chang CH, Lin SH, Su YF, Tsai YC, Yang SF, Lin CL
PeerJ 2021;9:e11395
PeerJ 2021;9:e11395
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Li YQ, Chen Y, Jiang SQ, Shi YY, Jiang XL, Wu SS, Zhou P, Wang HY, Li P, Li F
Frontiers in cell and developmental biology 2021;9:652310
Frontiers in cell and developmental biology 2021;9:652310
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Investigation on the Pathological Mechanism of Frequent Exacerbators With Chronic Obstructive Pulmonary Disease Based on the Characteristics of Respiratory Flora.
Ke L, Chen L, Yaling Y, Can G, Jun L, Chuan Z
Frontiers in medicine 2021;8:816802
Frontiers in medicine 2021;8:816802
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Ou G, Jiang X, Gao A, Li X, Lin Z, Pei S
Frontiers in veterinary science 2021;8:801407
Frontiers in veterinary science 2021;8:801407
Nuclear Factor Kappa-B/Homeobox A9-Mediated Modulation of Leucine-Rich Repeat Flightless-Interacting Protein 1 Is Involved in Advanced Glycation End Product-Induced Endothelial Dysfunction.
Zhu Q, Hu S, He Y, Qiu C, Chen T, He Y, Wu Z, Tian L, Shang T, Xiang Y, Zhang H, Li D
Journal of vascular research 2021;58(5):311-320
Journal of vascular research 2021;58(5):311-320
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Jun L, Lin-Lin S, Hui S
Molecular vision 2021;27:575-587
Molecular vision 2021;27:575-587
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy.
Yang K, Zeng L, Ge A, Yi Y, Wang S, Ge J
Oxidative medicine and cellular longevity 2021;2021:8879060
Oxidative medicine and cellular longevity 2021;2021:8879060
l-Theanine Ameliorates d-Galactose-Induced Brain Damage in Rats via Inhibiting AGE Formation and Regulating Sirtuin1 and BDNF Signaling Pathways.
Zeng L, Lin L, Chen L, Xiao W, Gong Z
Oxidative medicine and cellular longevity 2021;2021:8850112
Oxidative medicine and cellular longevity 2021;2021:8850112
Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose.
Guo J, Zhao D, Dong P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6583086
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
Zanthoxylum bungeanum Seed Oil Attenuates LPS-Induced BEAS-2B Cell Activation and Inflammation by Inhibiting the TLR4/MyD88/NF-κB Signaling Pathway.
Hou J, Wang J, Meng J, Zhang X, Niu Y, Gao J, Bai Y, Zhou J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2073296
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2073296
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J
International journal of biological sciences 2021;17(10):2633-2651
International journal of biological sciences 2021;17(10):2633-2651
Network Pharmacology Analysis of the Mechanisms of Compound Herba Sarcandrae (Fufang Zhongjiefeng) Aerosol in Chronic Pharyngitis Treatment.
Zhang Y, Yuan T, Li Y, Wu N, Dai X
Drug design, development and therapy 2021;15:2783-2803
Drug design, development and therapy 2021;15:2783-2803
The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain.
Yang T, Zhou Y, Zhang W, Zhang L, Chen S, Chen C, Gao F, Yang H, Manyande A, Wang J, Tian Y, Tian X
Journal of pain research 2021;14:441-452
Journal of pain research 2021;14:441-452
Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice.
Chen X, Yang K, Jin X, Meng Z, Liu B, Yu H, Lu P, Wang K, Fan Z, Tang Z, Zhang F, Liu C
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2753-2764
Quercetin Preserves Oral Cavity Health by Mitigating Inflammation and Microbial Dysbiosis.
Mooney EC, Holden SE, Xia XJ, Li Y, Jiang M, Banson CN, Zhu B, Sahingur SE
Frontiers in immunology 2021;12:774273
Frontiers in immunology 2021;12:774273
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X, Zheng Q
Frontiers in pharmacology 2021;12:771940
Frontiers in pharmacology 2021;12:771940
Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation.
Kong F, Ye S, Zhong Z, Zhou X, Zhou W, Liu Z, Lan J, Xiong Y, Ye Q
Frontiers in immunology 2021;12:767618
Frontiers in immunology 2021;12:767618
Aspartate Metabolism Facilitates IL-1β Production in Inflammatory Macrophages.
Wang H, Zheng X, Liu B, Xia Y, Xin Z, Deng B, He L, Deng J, Ren W
Frontiers in immunology 2021;12:753092
Frontiers in immunology 2021;12:753092
Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68 Infection-Induced Proinflammatory Responses.
Li J, Yang S, Liu S, Chen Y, Liu H, Su Y, Liu R, Cui Y, Song Y, Teng Y, Wang T
Frontiers in immunology 2021;12:749618
Frontiers in immunology 2021;12:749618
Maternal Overnutrition During Gestation in Sheep Alters Autophagy Associated Pathways in Offspring Heart.
Liu Y, Ding Q, Halderson SJ, Arriola Apelo SI, Jones AK, Pillai SM, Hoffman ML, Reed S, Govoni KE, Zinn SA, Guo W
Frontiers in genetics 2021;12:742704
Frontiers in genetics 2021;12:742704
Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
Yang B, Zhang G, Qin X, Huang Y, Ren X, Sun J, Ma S, Liu Y, Song D, Liu Y, Cui Y, Wang H, Wang J
Frontiers in immunology 2021;12:730483
Frontiers in immunology 2021;12:730483
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Selonsertib Alleviates the Progression of Rat Osteoarthritis: An in vitro and in vivo Study.
Yan J, Zhang Y, Sheng G, Ni B, Xiao Y, Wang S, Wang T, Ma Y, Wang H, Wu H, Tu C
Frontiers in pharmacology 2021;12:687033
Frontiers in pharmacology 2021;12:687033
Cronobacter sakazakii ATCC 29544 Translocated Human Brain Microvascular Endothelial Cells via Endocytosis, Apoptosis Induction, and Disruption of Tight Junction.
Jin T, Guan N, Du Y, Zhang X, Li J, Xia X
Frontiers in microbiology 2021;12:675020
Frontiers in microbiology 2021;12:675020
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages.
Jia L, Sha S, Yang S, Taj A, Ma Y
Frontiers in microbiology 2021;12:657726
Frontiers in microbiology 2021;12:657726
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development.
Lai MC, Zhu QQ, Xu J, Zhang WJ
American journal of cancer research 2021;11(9):4175-4198
American journal of cancer research 2021;11(9):4175-4198
CALR-TLR4 Complex Inhibits Non-Small Cell Lung Cancer Progression by Regulating the Migration and Maturation of Dendritic Cells.
Chen R, Huang M, Yang X, Chen XH, Shi MY, Li ZF, Chen ZN, Wang K
Frontiers in oncology 2021;11:743050
Frontiers in oncology 2021;11:743050
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, Hu H, Chen T, Tan B
Frontiers in oncology 2021;11:704001
Frontiers in oncology 2021;11:704001
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway.
Lv L, Yi Q, Yan Y, Chao F, Li M
Frontiers in oncology 2021;11:682773
Frontiers in oncology 2021;11:682773
Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR.
Kong L, Dong R, Huang K, Wang X, Wang D, Yue N, Wang C, Sun P, Gu J, Luo H, Liu K, Wu J, Sun H, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153629
Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise.
Lu J, Feng X, Zhang H, Wei Y, Yang Y, Tian Y, Bai L
Connective tissue research 2021 Sep;62(5):508-518
Connective tissue research 2021 Sep;62(5):508-518
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Yuan Y, Wang Z, Nan B, Yang C, Wang M, Ye H, Xi C, Zhang Y, Yan H
Toxicology 2021 Sep;461:152905
Toxicology 2021 Sep;461:152905
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Long noncoding RNA ANRIL knockdown attenuates neuroinflammation following ischemic stroke via suppressing the expression of NF-κB in vitro and in vivo.
Deng L, Guo Y, Liu J, Chen S, Wang X, Zhao H, Zuo T, Hu Q, Dong Z
Neurological research 2021 Sep;43(9):767-777
Neurological research 2021 Sep;43(9):767-777
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells.
Xu HZ, Li TF, Wang C, Ma Y, Liu Y, Zheng MY, Liu ZJ, Chen JB, Li K, Sun SK, Komatsu N, Xu YH, Zhao L, Chen X
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Journal of nanobiotechnology 2021 Sep 6;19(1):268
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Li TF, Xu HZ, Xu YH, Yu TT, Tang JM, Li K, Wang C, Peng XC, Li QR, Sang XY, Zheng MY, Liu Y, Zhao L, Chen X
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Molecular pharmaceutics 2021 Sep 6;18(9):3601-3615
Chondroprotective and antiarthritic effects of galangin in osteoarthritis: An in vitro and in vivo study.
Huang X, Pei W, Ni B, Zhang R, You H
European journal of pharmacology 2021 Sep 5;906:174232
European journal of pharmacology 2021 Sep 5;906:174232
JaponiconeA induces apoptosis of bortezomib-sensitive and -resistant myeloma cells in vitro and in vivo by targeting IKK.
Zhang Z, Ye C, Liu J, Xu W, Wu C, Yu Q, Xu X, Zeng X, Jin H, Wu Y, Yan H
Cancer biology & medicine 2021 Sep 28;19(5):651-68
Cancer biology & medicine 2021 Sep 28;19(5):651-68
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Arsenic exposure induces intestinal barrier damage and consequent activation of gut-liver axis leading to inflammation and pyroptosis of liver in ducks.
Zhong G, Wan F, Lan J, Jiang X, Wu S, Pan J, Tang Z, Hu L
The Science of the total environment 2021 Sep 20;788:147780
The Science of the total environment 2021 Sep 20;788:147780
TRIM38 protects chondrocytes from IL-1β-induced apoptosis and degeneration via negatively modulating nuclear factor (NF)-κB signaling.
Hu S, Li Y, Wang B, Peng K
International immunopharmacology 2021 Oct;99:108048
International immunopharmacology 2021 Oct;99:108048
Inhibition of TNFAIP1 ameliorates the oxidative stress and inflammatory injury in myocardial ischemia/reperfusion injury through modulation of Akt/GSK-3β/Nrf2 pathway.
Wen L, Yang QH, Ma XL, Li T, Xiao S, Sun CF
International immunopharmacology 2021 Oct;99:107993
International immunopharmacology 2021 Oct;99:107993
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.
Deng Y, Su W, Zhu J, Ji H, Zhou X, Geng J, Zhu J, Zhang Q
Journal for immunotherapy of cancer 2021 Oct;9(10)
Journal for immunotherapy of cancer 2021 Oct;9(10)
GFI1 promotes the proliferation and migration of esophageal squamous cell carcinoma cells through the inhibition of SOCS1 expression.
Huang Y, Ruan R, Fang Y, Wu K, Yao L, Zhang R, He W
International journal of molecular medicine 2021 Oct;48(4)
International journal of molecular medicine 2021 Oct;48(4)
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092
Environmental toxicology 2021 Oct;36(10):2073-2092
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65.
Zhou Y, Zhong B, Min X, Hou Y, Lin L, Wu Q, Shi J, Chen X
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Phytotherapy research : PTR 2021 Oct;35(10):5861-5870
Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury.
Li L, Liu S, Zhou Y, Zhao M, Wang Y, Wang C, Lou P, Huang R, Ma L, Lu Y, Fu P, Liu J
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Journal of cellular and molecular medicine 2021 Oct;25(20):9863-9877
Establishment of incontinence-associated dermatitis rat models and assessment of the therapeutic effects of zinc oxide, painless skin protective film and silicone dressing.
Chen G, Huang L, Chen Y, Zheng S, Zhu L, Ding M
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Experimental and therapeutic medicine 2021 Oct;22(4):1058
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Bai Y, Liu X, Chen Q, Chen T, Jiang N, Guo Z
Scientific reports 2021 Oct 4;11(1):19637
Scientific reports 2021 Oct 4;11(1):19637
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.
Qi M, Liu X, Zhou Y, Wang H, Zhao Y, Ren J, Xiang J
International journal of molecular sciences 2021 Oct 24;22(21)
International journal of molecular sciences 2021 Oct 24;22(21)
Cigarette smoking induces aberrant N(6)-methyladenosine of DAPK2 to promote non-small cell lung cancer progression by activating NF-κB pathway.
Jin M, Li G, Liu W, Wu X, Zhu J, Zhao D, Zeng Z, Xiong M, Song Y, He X, Zhang Q, Hu K
Cancer letters 2021 Oct 10;518:214-229
Cancer letters 2021 Oct 10;518:214-229
Downregulated fat mass and obesity-associated protein inhibits bone resorption and osteoclastogenesis by nuclear factor-kappa B inactivation.
Zhuang J, Ning H, Wang M, Zhao W, Jing Y, Liu X, Zu J, Kong P, Wang X, Sun C, Yan J
Cellular signalling 2021 Nov;87:110137
Cellular signalling 2021 Nov;87:110137
FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells.
Huang H, Wang Y, Huang T, Wang L, Liu Y, Wu Q, Yu A, Shi M, Wang X, Li W, Zhang J, Liu Y
Journal of physiology and biochemistry 2021 Nov;77(4):625-638
Journal of physiology and biochemistry 2021 Nov;77(4):625-638
Knockdown of ST6Gal-I expression in human hepatocellular carcinoma cells inhibits their exosome-mediated proliferation- and migration-promoting effects.
Wang L, Chen X, Wang L, Wang S, Li W, Liu Y, Zhang J
IUBMB life 2021 Nov;73(11):1378-1391
IUBMB life 2021 Nov;73(11):1378-1391
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice.
Zhao W, Chen L, Zhou H, Deng C, Han Q, Chen Y, Wu Q, Li S
Molecular medicine reports 2021 Nov;24(5)
Molecular medicine reports 2021 Nov;24(5)
The epigenetic regulator BRD4 is involved in cadmium-triggered inflammatory response in rat kidney.
Gong Z, Liu G, Liu W, Zou H, Song R, Zhao H, Yuan Y, Gu J, Bian J, Zhu J, Liu Z
Ecotoxicology and environmental safety 2021 Nov;224:112620
Ecotoxicology and environmental safety 2021 Nov;224:112620
Overexpression of the nucleoporin Nup88 stimulates migration and invasion of HeLa cells.
Makise M, Uchimura R, Higashi K, Mashiki Y, Shiraishi R, Shutoku Y, Kuniyasu A
Histochemistry and cell biology 2021 Nov;156(5):409-421
Histochemistry and cell biology 2021 Nov;156(5):409-421
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway.
Zhang L, Liu M, Liu W, Hu C, Li H, Deng J, Cao Q, Wang Y, Hu W, Li Q
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Laboratory investigation; a journal of technical methods and pathology 2021 Nov;101(11):1418-1426
Oxymatrine inhibits neuroinflammation byRegulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway.
Wang XL, Chen F, Shi H, Zhang M, Yan L, Pei XY, Peng XD
International immunopharmacology 2021 Nov;100:108139
International immunopharmacology 2021 Nov;100:108139
Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through Suppression of NF-κB Activation.
Liu X, Su J, Wang G, Zheng L, Wang G, Sun Y, Bao Y, Wang S, Huang Y
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration.
Li Y, Su G, Zhong Y, Xiong Z, Huang T, Quan J, Huang J, Wen X, Luo C, Zheng W, Chen J, Cheng J, Yao W, Lai T
BMC pulmonary medicine 2021 Nov 6;21(1):347
BMC pulmonary medicine 2021 Nov 6;21(1):347
Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats.
Yuan Y, Lu L, Bo N, Chaoyue Y, Haiyang Y
Journal of agricultural and food chemistry 2021 Nov 3;69(43):12837-12852
Journal of agricultural and food chemistry 2021 Nov 3;69(43):12837-12852
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Wang C, Huang H
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
TRPV4-induced Müller cell gliosis and TNF-α elevation-mediated retinal ganglion cell apoptosis in glaucomatous rats via JAK2/STAT3/NF-κB pathway.
Li Q, Cheng Y, Zhang S, Sun X, Wu J
Journal of neuroinflammation 2021 Nov 17;18(1):271
Journal of neuroinflammation 2021 Nov 17;18(1):271
Intermittent hypoxia aggravates non-alcoholic fatty liver disease via RIPK3-dependent necroptosis-modulated Nrf2/NFκB signaling pathway.
Zhang H, Zhou L, Zhou Y, Wang L, Jiang W, Liu L, Yue S, Zheng P, Liu H
Life sciences 2021 Nov 15;285:119963
Life sciences 2021 Nov 15;285:119963
Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM(2.5)-induced lung injury in rats by modulating the NF-κB pathway.
Yao H, Zhao J, Zhu L, Xie Y, Zhao N, Yao R, Sun H, Han G
Journal of ethnopharmacology 2021 Nov 15;280:114420
Journal of ethnopharmacology 2021 Nov 15;280:114420
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
Zhuang J, Zhou X, Liu T, Zhang S, Yuan F, Zhang L, Yang Z, Chen Y
Die Pharmazie 2021 Nov 1;76(11):551-558
Die Pharmazie 2021 Nov 1;76(11):551-558
LncRNA NEAT1 mediates intestinal inflammation by regulating TNFRSF1B.
Pan S, Liu R, Wu X, Ma K, Luo W, Nie K, Zhang C, Meng X, Tong T, Chen X, Wang X, Deng M
Annals of translational medicine 2021 May;9(9):773
Annals of translational medicine 2021 May;9(9):773
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
Hu J, Huo S, Dou S, Jiang W, Li Y
General physiology and biophysics 2021 May;40(3):161-171
General physiology and biophysics 2021 May;40(3):161-171
TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS.
Zhong BR, Zhou GF, Song L, Wen QX, Deng XJ, Ma YL, Hu LT, Chen GJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21445
Targeted regulation of lymphocytic ER stress response with an overall immunosuppression to alleviate allograft rejection.
Shi Y, Lu Y, Zhu C, Luo Z, Li X, Liu Y, Jiang M, Liu X, Luo L, Du Y, You J
Biomaterials 2021 May;272:120757
Biomaterials 2021 May;272:120757
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Wang C, Wang X, Han A, Wang Y, Jiang H
Experimental and therapeutic medicine 2021 May;21(5):470
Experimental and therapeutic medicine 2021 May;21(5):470
Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression.
Li KY, Xiang XJ, Song L, Chen J, Luo B, Wen QX, Zhong BR, Zhou GF, Deng XJ, Ma YL, Hu LT, Chen GJ
Journal of neurochemistry 2021 May;157(4):1351-1365
Journal of neurochemistry 2021 May;157(4):1351-1365
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo.
Zhang C, Li Q, Qin G, Zhang Y, Li C, Han L, Wang R, Wang S, Chen H, Liu K, He C
Chinese medicine 2021 May 31;16(1):41
Chinese medicine 2021 May 31;16(1):41
Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke.
Gao C, Jia W, Xu W, Wu Q, Wu J
Journal of neuroinflammation 2021 May 22;18(1):118
Journal of neuroinflammation 2021 May 22;18(1):118
A hybrid membrane coating nanodrug system against gastric cancer via the VEGFR2/STAT3 signaling pathway.
Long Y, Wang Z, Fan J, Yuan L, Tong C, Zhao Y, Liu B
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Journal of materials chemistry. B 2021 May 12;9(18):3838-3855
Anti-inflammatory activity of the water extract of Chloranthus serratus roots in LPS-stimulated RAW264.7 cells mediated by the Nrf2/HO-1, MAPK and NF-κB signaling pathways.
Sun S, Zhang J, Li H, Du Y, Li S, Li A, Suo X, Wang Y, Sun Q
Journal of ethnopharmacology 2021 May 10;271:113880
Journal of ethnopharmacology 2021 May 10;271:113880
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
Macrophage regulator of G-protein signaling 12 contributes to inflammatory pain hypersensitivity.
Yuan G, Yang S, Gautam M, Luo W, Yang S
Annals of translational medicine 2021 Mar;9(6):448
Annals of translational medicine 2021 Mar;9(6):448
Triptolide reduces salivary gland damage in a non-obese diabetic mice model of Sjögren's syndrome via JAK/STAT and NF-κB signaling pathways.
Guo Y, Ji W, Lu Y, Wang Y
Journal of clinical biochemistry and nutrition 2021 Mar;68(2):131-138
Journal of clinical biochemistry and nutrition 2021 Mar;68(2):131-138
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Li X, Zhou W, Li Z, Guan F
Autoimmunity 2021 Mar;54(2):114-128
Autoimmunity 2021 Mar;54(2):114-128
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Crosstalk between adipocytes and M2 macrophages compensates for osteopenic phenotype in the Lrp5-deficient mice.
Li L, Qiu X, Zhang N, Sun Y, Wang Y, Wang L
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):572-583
Experimental biology and medicine (Maywood, N.J.) 2021 Mar;246(5):572-583
The miR-623/CXCL12 axis inhibits LPS-induced nucleus pulposus cell apoptosis and senescence.
Zhong H, Zhou Z, Guo L, Liu F, Zheng B, Bi S, Tian C
Mechanisms of ageing and development 2021 Mar;194:111417
Mechanisms of ageing and development 2021 Mar;194:111417
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Xie C, Ma H, Shi Y, Li J, Wu H, Wang B, Shao Z, Huang C, Chen J, Sun L, Zhou Y, Tian N, Wu Y, Gao W, Wu A, Wang X, Zhang X
Food & function 2021 Mar 21;12(6):2703-2714
Food & function 2021 Mar 21;12(6):2703-2714
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Li J, Zhang X, Wang T, Li J, Su Q, Zhong C, Chen Z, Liang Y
Life sciences 2021 Mar 15;269:119085
Life sciences 2021 Mar 15;269:119085
Effect of selenium-enriched kiwifruit on body fat reduction and liver protection in hyperlipidaemic mice.
Zhang X, Xia H, Wang J, Leng R, Zhou X, Gao Q, He K, Liu D, Huang B
Food & function 2021 Mar 15;12(5):2044-2057
Food & function 2021 Mar 15;12(5):2044-2057
A New Perspective on Ameliorating Depression-Like Behaviors: Suppressing Neuroinflammation by Upregulating PGC-1α.
Fu X, Jiao J, Qin T, Yu J, Fu Q, Deng X, Ma S, Ma Z
Neurotoxicity research 2021 Jun;39(3):872-885
Neurotoxicity research 2021 Jun;39(3):872-885
Wogonin alleviates liver injury in sepsis through Nrf2-mediated NF-κB signalling suppression.
Dai JM, Guo WN, Tan YZ, Niu KW, Zhang JJ, Liu CL, Yang XM, Tao KS, Chen ZN, Dai JY
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
Journal of cellular and molecular medicine 2021 Jun;25(12):5782-5798
NF‑κB is negatively associated with Nurr1 to reduce the inflammatory response in Parkinson's disease.
Gao H, Wang D, Jiang S, Mao J, Yang X
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Zong X, Xiao X, Shen B, Jiang Q, Wang H, Lu Z, Wang F, Jin M, Min J, Wang F, Wang Y
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Li G, LeiQian, Gu P, Fan D
BMC anesthesiology 2021 Jun 28;21(1):180
BMC anesthesiology 2021 Jun 28;21(1):180
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
MiR-519d-5p modulates the sensitivity of breast cancer to chemotherapy by forming a negative feedback loop with RELA.
Li D, Wang T, Yu Z, Zhang Y, Wu X, Zheng N, Zhang W, Wu L
Annals of translational medicine 2021 Jul;9(14):1171
Annals of translational medicine 2021 Jul;9(14):1171
IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection.
Jiang Z, Wei F, Zhang Y, Wang T, Gao W, Yu S, Sun H, Pu J, Sun Y, Wang M, Tong Q, Gao C, Chang KC, Liu J
Nature microbiology 2021 Jul;6(7):932-945
Nature microbiology 2021 Jul;6(7):932-945
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Deng L, Guo Y, Liu J, Wang X, Chen S, Wang Q, Rao J, Wang Y, Zuo T, Hu Q, Zhao X, Dong Z
Neurochemical research 2021 Jul;46(7):1801-1813
Neurochemical research 2021 Jul;46(7):1801-1813
Effects of medicine food Fructus Gardeniae on liver and kidney functions after oral administration to rats for 12 weeks.
Li C, Gao X, Gao X, Lv J, Bian X, Lv J, Sun J, Luo G, Zhang H
Journal of food biochemistry 2021 Jul;45(7):e13752
Journal of food biochemistry 2021 Jul;45(7):e13752
N-acetylserotonin alleviated the expression of interleukin-1β in retinal ischemia-reperfusion rats via the TLR4/NF-κB/NLRP3 pathway.
Liu J, Zhang N, Zhang M, Yin H, Zhang X, Wang X, Wang X, Zhao Y
Experimental eye research 2021 Jul;208:108595
Experimental eye research 2021 Jul;208:108595
GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice.
Zhang LQ, Zhang W, Li T, Yang T, Yuan X, Zhou Y, Zou Q, Yang H, Gao F, Tian Y, Mei W, Tian XB
Neurobiology of learning and memory 2021 Jul;182:107463
Neurobiology of learning and memory 2021 Jul;182:107463
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
Geng M, Hua Y, Liu Y, Quan J, Hu X, Su P, Li Y, Liu X, Li Q, Zhu T
Genomics 2021 Jul;113(4):2756-2768
Genomics 2021 Jul;113(4):2756-2768
Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity.
Wang Y, Song Z, Guo Y, Xie H, Zhang Z, Sun D, Li H, Chen L
Bioorganic chemistry 2021 Jul;112:104944
Bioorganic chemistry 2021 Jul;112:104944
Baicalein Delays H(2)O(2)-Induced Astrocytic Senescence through Inhibition of Senescence-Associated Secretory Phenotype (SASP), Suppression of JAK2/STAT1/NF-κB Pathway, and Regulation of Leucine Metabolism.
Gao L, Zheng WG, Wu XK, Du GH, Qin XM
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
ACS chemical neuroscience 2021 Jul 7;12(13):2320-2335
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195
Cell death discovery 2021 Jul 26;7(1):195
Adjuvant treatment and molecular mechanism of probiotic compounds in patients with gastric cancer after gastrectomy.
Zheng C, Chen T, Lu J, Wei K, Tian H, Liu W, Xu T, Wang X, Wang S, Yang R, Yang Y, Liu Z, Wei H, Deng X
Food & function 2021 Jul 21;12(14):6294-6308
Food & function 2021 Jul 21;12(14):6294-6308
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
Song C, Chen J, Li X, Yang R, Cao X, Zhou L, Zhou Y, Ying H, Zhang Q, Sun Y
International immunopharmacology 2021 Jan;90:107161
International immunopharmacology 2021 Jan;90:107161
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151
International immunopharmacology 2021 Jan;90:107151
Hyperoside ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
Sun K, Luo J, Jing X, Xiang W, Guo J, Yao X, Liang S, Guo F, Xu T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153387
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;80:153387
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
He L, Wang Z, Zhou R, Xiong W, Yang Y, Song N, Qian J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110993
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110993
miR-34a-5p up-regulates the IL-1β/COX2/PGE2 inflammation pathway and induces the release of CGRP via inhibition of SIRT1 in rat trigeminal ganglion neurons.
Zhang H, Zhang XM, Zong DD, Ji XY, Jiang H, Zhang FZ, He SD
FEBS open bio 2021 Jan;11(1):300-311
FEBS open bio 2021 Jan;11(1):300-311
Diosmetin Ameliorates Nonalcoholic Steatohepatitis through Modulating Lipogenesis and Inflammatory Response in a STAT1/CXCL10-Dependent Manner.
Luo N, Yang C, Zhu Y, Chen Q, Zhang B
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
Journal of agricultural and food chemistry 2021 Jan 20;69(2):655-667
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Jiao Y, Zhao D, Gao F, Hu X, Hu X, Li M, Cui Y, Wei X, Xie C, Zhao Y, Gao Y
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Inhibitory activity of narirutin on RBL-2H3 cells degranulation.
Niu L, Wei J, Li X, Jin Y, Shi X
Immunopharmacology and immunotoxicology 2021 Feb;43(1):68-76
Immunopharmacology and immunotoxicology 2021 Feb;43(1):68-76
Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway.
Qiu C, Yang LD, Yu W, Tian DD, Gao MR, Wang WJ, Li XB, Wu YM, Wang M
Metabolic brain disease 2021 Feb;36(2):273-283
Metabolic brain disease 2021 Feb;36(2):273-283
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Inflammatory signals induce MUC16 expression in ovarian cancer cells via NF-κB activation.
Liu J, Li L, Luo N, Liu Q, Liu L, Chen D, Cheng Z, Xi X
Experimental and therapeutic medicine 2021 Feb;21(2):163
Experimental and therapeutic medicine 2021 Feb;21(2):163
Exercise reduces hyperlipidemia-induced kidney damage in apolipoprotein E-deficient mice.
Qian C, Yang Q, Guo L, Zhu H, You X, Liu H, Sun Y
Experimental and therapeutic medicine 2021 Feb;21(2):153
Experimental and therapeutic medicine 2021 Feb;21(2):153
Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution.
Cheng X, Sun B, Liu S, Li D, Yang X, Zhang Y
Experimental and therapeutic medicine 2021 Feb;21(2):142
Experimental and therapeutic medicine 2021 Feb;21(2):142
Poly(ADP-ribose) polymerase-1 inhibitor ameliorates dextran sulfate sodium-induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF-κB signaling pathway.
Peng S, Shen L, Tian MX, Li HM, Wang SS
Experimental and therapeutic medicine 2021 Feb;21(2):134
Experimental and therapeutic medicine 2021 Feb;21(2):134
m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, Li D, Han X
Autophagy 2021 Feb;17(2):457-475
Autophagy 2021 Feb;17(2):457-475
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
Escalating dose-multiple binge methamphetamine treatment elicits neurotoxicity, altering gut microbiota and fecal metabolites in mice.
Chen LJ, Zhi X, Zhang KK, Wang LB, Li JH, Liu JL, Xu LL, Yoshida JS, Xie XL, Wang Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Feb;148:111946
Ripened Pu-erh Tea Extract Promotes Gut Microbiota Resilience against Dextran Sulfate Sodium Induced Colitis.
Huang Y, Yang Q, Mi X, Qiu L, Tao X, Zhang Z, Xia J, Wu Q, Wei H
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2190-2203
Journal of agricultural and food chemistry 2021 Feb 24;69(7):2190-2203
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
HUCMSCs transplantation combined with ultrashort wave therapy attenuates neuroinflammation in spinal cord injury through NUR77/ NF-κB pathway.
Wang S, Jia Y, Cao X, Feng S, Na L, Dong H, Gao J, Zhang L
Life sciences 2021 Feb 15;267:118958
Life sciences 2021 Feb 15;267:118958
Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway.
Qi MY, He YH, Cheng Y, Fang Q, Ma RY, Zhou SJ, Hao JQ
Food & function 2021 Feb 15;12(3):1241-1251
Food & function 2021 Feb 15;12(3):1241-1251
Protection Mechanisms Underlying Oral Administration of Chlorogenic Acid against Cadmium-Induced Hepatorenal Injury Related to Regulating Intestinal Flora Balance.
Ding Y, Li X, Liu Y, Wang S, Cheng D
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1675-1683
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1675-1683
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophages after hypoxia/reoxygenation injury.
Guo S, Dong L, Li J, Chen Y, Yao Y, Zeng R, Shushakova N, Haller H, Xu G, Rong S
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Chronic diseases and translational medicine 2021 Dec;7(4):254-265
Simiao Qingwen Baidu decoction inhibits Epstein-Barr virus-induced B lymphoproliferative disease and lytic viral replication.
Yang X, Liu L, Zhang H, Sun X, Yan Y, Ran R
Pharmaceutical biology 2021 Dec;59(1):741-747
Pharmaceutical biology 2021 Dec;59(1):741-747
Bergenin alleviates H(2) O(2) -induced oxidative stress and apoptosis in nucleus pulposus cells: Involvement of the PPAR-γ/NF-κB pathway.
Zhang G, Wang H, Zhang Q, Zhao Z, Zhu W, Zuo X
Environmental toxicology 2021 Dec;36(12):2541-2550
Environmental toxicology 2021 Dec;36(12):2541-2550
Amelioratory effect of neoandrographolide on myocardial ischemic-reperfusion injury by its anti-inflammatory and anti-apoptotic activities.
Liu Y, Liu Y, Zhang HL, Yu FF, Yin XR, Zhao YF, Ye F, Wu XQ
Environmental toxicology 2021 Dec;36(12):2367-2379
Environmental toxicology 2021 Dec;36(12):2367-2379
Morinda officinalis oligosaccharides alleviate depressive-like behaviors in post-stroke rats via suppressing NLRP3 inflammasome to inhibit hippocampal inflammation.
Li Z, Xu H, Xu Y, Lu G, Peng Q, Chen J, Bi R, Li J, Chen S, Li H, Jin H, Hu B
CNS neuroscience & therapeutics 2021 Dec;27(12):1570-1586
CNS neuroscience & therapeutics 2021 Dec;27(12):1570-1586
Expression and role of interleukin-1β and associated biomarkers in deep vein thrombosis.
Pai RZ, Fang Q, Tian G, Zhu B, Ge X
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Experimental and therapeutic medicine 2021 Dec;22(6):1366
Diterpenoid alkaloids from Delphinium forrestii var. viride and their anti-inflammation activity.
Song Z, Gao C, Jiang Q, Xu J, Xiong L, Liu K, Sun D, Li H, Chen L
Phytochemistry 2021 Dec;192:112971
Phytochemistry 2021 Dec;192:112971
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats.
Gu JY, Xu YW, Feng LP, Dong J, Zhao LQ, Liu C, Wang HY, Zhang XY, Song C, Wang CH
Brain research bulletin 2021 Dec;177:252-262
Brain research bulletin 2021 Dec;177:252-262
Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia.
Issotina Zibrila A, Li Y, Wang Z, Zhao G, Liu H, Leng J, Ahasan Ali M, Ampofo Osei J, Kang YM, Liu J
International immunopharmacology 2021 Dec;101(Pt B):108365
International immunopharmacology 2021 Dec;101(Pt B):108365
ILC2s induce adaptive Th2-type immunity in different stages of tuberculosis through the Notch-GATA3 pathway.
Li Q, Zhang J, Ma L, Wu C, Zhao J, Guan W, Li X, Yang X, Wen F
International immunopharmacology 2021 Dec;101(Pt B):108330
International immunopharmacology 2021 Dec;101(Pt B):108330
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
Zhu Y, Sun D, Liu H, Sun L, Jie J, Luo J, Peng L, Song L
International immunopharmacology 2021 Dec;101(Pt B):108266
International immunopharmacology 2021 Dec;101(Pt B):108266
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Zhang L, Zhu T, He F, Li X
International immunopharmacology 2021 Dec;101(Pt B):108238
International immunopharmacology 2021 Dec;101(Pt B):108238
Sub-chronic exposure to realgar induces liver injury via upregulating the TXNIP/NLRP3 pathway and disturbing bile acid homeostasis in mice.
Li A, Wu X, Yang J, Li J, Guo H, Zhang Y, Jiang H, Huo T
Journal of ethnopharmacology 2021 Dec 5;281:114584
Journal of ethnopharmacology 2021 Dec 5;281:114584
Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways.
Wang X, Chen S, Zhao L, Shi X
International immunopharmacology 2021 Aug;97:107506
International immunopharmacology 2021 Aug;97:107506
Guanosine and uridine alleviate airway inflammation via inhibition of the MAPK and NF-κB signals in OVA-induced asthmatic mice.
Luo Y, Chen H, Huang R, Wu Q, Li Y, He Y
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Pulmonary pharmacology & therapeutics 2021 Aug;69:102049
Protective effects of miR-155-5p silencing on IFN-γ-induced apoptosis and inflammation in salivary gland epithelial cells.
Zhang J, Zhu L, Shi H, Zheng H
Experimental and therapeutic medicine 2021 Aug;22(2):882
Experimental and therapeutic medicine 2021 Aug;22(2):882
Inhibitor of apoptosis-stimulating p53 protein protects against inflammatory bowel disease in mice models by inhibiting the nuclear factor kappa B signaling.
Qian K, Yuan L, Wang S, Kuang Y, Jin Q, Long D, Jiang Y, Zhao H, Liu K, Yao H
Clinical and experimental immunology 2021 Aug;205(2):246-256
Clinical and experimental immunology 2021 Aug;205(2):246-256
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke depression.
Hou X, Liu H, Ping Y, Zhang F, Zhi L, Jiang X, Zhang F, Song C, Zhang Z, Song J
Brain research bulletin 2021 Aug;173:74-81
Brain research bulletin 2021 Aug;173:74-81
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Liu DD, Luo P, Gu L, Zhang Q, Gao P, Zhu Y, Chen X, Guo Q, Zhang J, Ma N, Wang J
Journal of neuroinflammation 2021 Aug 9;18(1):174
Journal of neuroinflammation 2021 Aug 9;18(1):174
Ginsenoside Rg5 Improves Insulin Resistance and Mitochondrial Biogenesis of Liver via Regulation of the Sirt1/PGC-1α Signaling Pathway in db/db Mice.
Zhu Y, Yang H, Deng J, Fan D
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Journal of agricultural and food chemistry 2021 Aug 4;69(30):8428-8439
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.
Torres-Querol C, Torres P, Vidal N, Portero-Otín M, Arque G, Purroy F
Scientific reports 2021 Aug 3;11(1):15752
Scientific reports 2021 Aug 3;11(1):15752
Heteronemin Suppresses Lymphangiogenesis through ARF-1 and MMP-9/VE-Cadherin/Vimentin.
Chen HL, Su YC, Chen HC, Su JH, Wu CY, Wang SW, Lin IP, Chen CY, Lee CH
Biomedicines 2021 Aug 29;9(9)
Biomedicines 2021 Aug 29;9(9)
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
Fab Fragment of Immunoglobulin Y Modulates NF-κB and MAPK Signaling through TLR4 and αVβ3 Integrin and Inhibits the Inflammatory Effect on R264.7 Macrophages.
Zhou X, Ahn DU, Xia M, Zeng Q, Li X, Cai Z
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8747-8757
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8747-8757
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Li H, Yuan L, Li X, Luo Y, Zhang Z, Li J
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions.
Khanh VC, Fukushige M, Chang YH, Hoang NN, Yamashita T, Obata-Yasuoka M, Hamada H, Osaka M, Hiramatsu Y, Ohneda O
Stem cells and development 2021 Aug 1;30(15):758-772
Stem cells and development 2021 Aug 1;30(15):758-772
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Sang W, Xue S, Jiang Y, Lu H, Zhu L, Wang C, Ma J
Life sciences 2021 Aug 1;278:119528
Life sciences 2021 Aug 1;278:119528
Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway.
Zheng X, Liu H, Ma M, Ji J, Zhu F, Sun L
Archives of pharmacal research 2021 Apr;44(4):427-438
Archives of pharmacal research 2021 Apr;44(4):427-438
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Zhuo Y, Guo Z, Ba T, Zhang C, He L, Zeng C, Dai H
Virologica Sinica 2021 Apr;36(2):176-186
Virologica Sinica 2021 Apr;36(2):176-186
Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.
Yang C, Zuo Q, Liu X, Zhao Q, Pu H, Gao L, Zhao L, Guo Z, Lin Y, Liu J, Bi J, Yin G
Veterinary microbiology 2021 Apr;255:109016
Veterinary microbiology 2021 Apr;255:109016
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Tian S, Liao L, Zhou Q, Huang X, Zheng P, Guo Y, Deng T, Tian X
Oncology letters 2021 Apr;21(4):286
Oncology letters 2021 Apr;21(4):286
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
Lu HY, Hsu HL, Li CH, Li SJ, Lin SJ, Shih CM, Shih CC
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
Antioxidants (Basel, Switzerland) 2021 Apr 27;10(5)
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Jiang Y, Yu X, Zhao Y, Huang J, Li T, Chen H, Zhou J, Huang Z, Yang Z
Biomolecules 2021 Apr 12;11(4)
Biomolecules 2021 Apr 12;11(4)
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Zhang T, Li H, Wang K, Xu B, Chen ZN, Bian H
Frontiers in cell and developmental biology 2020;8:784
Frontiers in cell and developmental biology 2020;8:784
Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.
Lv JJ, Wang H, Cui HY, Liu ZK, Zhang RY, Lu M, Li C, Yong YL, Liu M, Zhang H, Zhang TJ, Zhang K, Li G, Nan G, Zhang C, Guo SP, Wang L, Chen ZN, Bian H
Frontiers in cell and developmental biology 2020;8:609090
Frontiers in cell and developmental biology 2020;8:609090
Chronic intermittent hypoxia vs chronic continuous hypoxia: Effects on vascular endothelial function and myocardial contractility.
Zhu J, Kang J, Li X, Wang M, Shang M, Luo Y, Xiong M, Hu K
Clinical hemorheology and microcirculation 2020;74(4):417-427
Clinical hemorheology and microcirculation 2020;74(4):417-427
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Han S, Li X, Liu J, Zou Z, Luo L, Wu R, Zhao Z, Wang C, Shen B
Frontiers in veterinary science 2020;7:529
Frontiers in veterinary science 2020;7:529
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
Yuan L, Bai D, Meng L, Wang H, Sun Z, An T, Chen Z, Deng X, Zhang X
The Journal of toxicological sciences 2020;45(8):411-422
The Journal of toxicological sciences 2020;45(8):411-422
GNAS promotes inflammation-related hepatocellular carcinoma progression by promoting STAT3 activation.
Ding H, Zhang X, Su Y, Jia C, Dai C
Cellular & molecular biology letters 2020;25:8
Cellular & molecular biology letters 2020;25:8
Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs.
Zha A, Cui Z, Qi M, Liao S, Chen L, Liao P, Tan B
Current drug metabolism 2020;21(8):614-625
Current drug metabolism 2020;21(8):614-625
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Li QT, Qiu MJ, Yang SL, Fang X, He XX, Wang MM, Li YN, Xiong ZF, Huang S
Journal of oncology 2020;2020:9327512
Journal of oncology 2020;2020:9327512
Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health.
Yin S, Bai X, Xin D, Li T, Chu X, Ke H, Han M, Chen W, Li X, Wang Z
Neural plasticity 2020;2020:8815195
Neural plasticity 2020;2020:8815195
Effects of Saccharides from Arctium lappa L. Root on FeCl(3)-Induced Arterial Thrombosis via the ERK/NF-κB Signaling Pathway.
Qiu T, Zhou H, Li S, Tian N, Li Z, Wang R, Sun P, Peng J, Du J, Ma X, Diao Y, Lv L, Wang L, Li H
Oxidative medicine and cellular longevity 2020;2020:7691352
Oxidative medicine and cellular longevity 2020;2020:7691352
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
Chen Y, Feng B, Yuan Y, Hu J, Zhao W, Jiang H, Li W, Fan Z, Du Z
Mediators of inflammation 2020;2020:6318520
Mediators of inflammation 2020;2020:6318520
The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets.
Zha A, Yuan D, Cui Z, Qi M, Liao S, Liao P, Tan B
Oxidative medicine and cellular longevity 2020;2020:5363546
Oxidative medicine and cellular longevity 2020;2020:5363546
The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ET(A) Receptor in Mouse Mesenteric Arteries.
Xie X, Chen C, Xu CB, Lin J, Cao L, Chen G, Li J
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Advances in pharmacological and pharmaceutical sciences 2020;2020:5070436
Thymoquinone Protects against Hyperlipidemia-Induced Cardiac Damage in Low-Density Lipoprotein Receptor-Deficient (LDL-R(-/-)) Mice via Its Anti-inflammatory and Antipyroptotic Effects.
Pei ZW, Guo Y, Zhu HL, Dong M, Zhang Q, Wang F
BioMed research international 2020;2020:4878704
BioMed research international 2020;2020:4878704
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Zhang B, Yue R, Chen Y, Huang X, Yang M, Shui J, Peng Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
Guo LP, Liu SX, Yang Q, Liu HY, Xu LL, Hao YH, Zhang XQ
BioMed research international 2020;2020:1594726
BioMed research international 2020;2020:1594726
PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model.
He X, Li T, Luo L, Zeng H, Chen Y, Cai S
Tobacco induced diseases 2020;18:8
Tobacco induced diseases 2020;18:8
Ozone Therapy Attenuates NF-κB-Mediated Local Inflammatory Response and Activation of Th17 Cells in Treatment for Psoriasis.
Zeng J, Lei L, Zeng Q, Yao Y, Wu Y, Li Q, Gao L, Du H, Xie Y, Huang J, Tan W, Lu J
International journal of biological sciences 2020;16(11):1833-1845
International journal of biological sciences 2020;16(11):1833-1845
Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells.
Tong D, Ma Z, Su P, Wang S, Xu Y, Zhang LM, Wu Z, Liu K, Zhao P
Frontiers in cellular neuroscience 2020;14:590577
Frontiers in cellular neuroscience 2020;14:590577
Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling.
Gao Z, Sui J, Fan R, Qu W, Dong X, Sun D
Drug design, development and therapy 2020;14:1971-1982
Drug design, development and therapy 2020;14:1971-1982
Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway.
Liao D, Chen Y, Guo Y, Wang C, Liu N, Gong Q, Fu Y, Fu Y, Cao L, Yao D, Jiang P
Journal of inflammation research 2020;13:195-206
Journal of inflammation research 2020;13:195-206
β-catenin regulates myocardial ischemia/reperfusion injury following heterotopic heart transplantation in mice by modulating PTEN pathways.
Ban Q, Qiao L, Xia H, Xie B, Liu J, Ma Y, Zhang L, Zhang M, Liu LG, Jiao W, Yang S, Li Z, Zheng S, Liu D, Xia J, Qi Z
American journal of translational research 2020;12(8):4757-4771
American journal of translational research 2020;12(8):4757-4771
The LINC00365/SCGB2A1 (Mammaglobin B) Axis Down-Regulates NF-κB Signaling and Is Associated with the Progression of Gastric Cancer.
Yan XY, Zhang JJ, Zhong XR, Yu SH, Xu L, Tian R, Sun LK, Su J
Cancer management and research 2020;12:621-631
Cancer management and research 2020;12:621-631
Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.
Li M, Meng N, Guo X, Niu X, Zhao Z, Wang W, Xie X, Lv P
Frontiers in aging neuroscience 2020;12:137
Frontiers in aging neuroscience 2020;12:137
Resatorvid Relieves Breast Cancer Complicated with Depression by Inactivating Hippocampal Microglia Through TLR4/NF-κB/NLRP3 Signaling Pathway.
Luo W, Han Y, Meng P, Yang Q, Zhao H, Ling J, Wang Y
Cancer management and research 2020;12:13003-13014
Cancer management and research 2020;12:13003-13014
Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy.
Wei A, Xiao H, Xu G, Yu X, Guo J, Jing Z, Shi S, Song Y
Frontiers in pharmacology 2020;11:762
Frontiers in pharmacology 2020;11:762
Astragaloside IV Improves High-Fat Diet-Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway.
Liu YL, Zhang QZ, Wang YR, Fu LN, Han JS, Zhang J, Wang BM
Frontiers in pharmacology 2020;11:605064
Frontiers in pharmacology 2020;11:605064
Chemical Fingerprint Analysis and Ultra-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Study of the Protective Effect of Buxue Yimu Granule in Medical-Induced Incomplete Abortion Rats.
Zhang Y, Li W, Chen TT, Yang Y, Wu MY, Luo JY, Gong Y, Zou L
Frontiers in pharmacology 2020;11:578217
Frontiers in pharmacology 2020;11:578217
Inhibitory Effects of the Lactobacillus rhamnosus GG Effector Protein HM0539 on Inflammatory Response Through the TLR4/MyD88/NF-кB Axis.
Li Y, Yang S, Lun J, Gao J, Gao X, Gong Z, Wan Y, He X, Cao H
Frontiers in immunology 2020;11:551449
Frontiers in immunology 2020;11:551449
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Cai M, Liao Z, Zou X, Xu Z, Wang Y, Li T, Li Y, Ou X, Deng Y, Guo Y, Peng T, Li M
Frontiers in immunology 2020;11:549
Frontiers in immunology 2020;11:549
Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis.
Zhang S, Feng Z, Gao W, Duan Y, Fan G, Geng X, Wu B, Li K, Liu K, Peng C
Frontiers in pharmacology 2020;11:544124
Frontiers in pharmacology 2020;11:544124
Sodium Butyrate Abrogates the Growth and Pathogenesis of Mycobacterium bovis via Regulation of Cathelicidin (LL37) Expression and NF-κB Signaling.
Zhang K, Hussain T, Wang J, Li M, Wang W, Ma X, Liao Y, Yao J, Song Y, Liang Z, Zhou X, Xu L
Frontiers in microbiology 2020;11:433
Frontiers in microbiology 2020;11:433
Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells.
Li L, Luo D, Liao Y, Peng K, Zeng Y
Frontiers in immunology 2020;11:2052
Frontiers in immunology 2020;11:2052
Serine Supports IL-1β Production in Macrophages Through mTOR Signaling.
Chen S, Xia Y, He F, Fu J, Xin Z, Deng B, He L, Zhou X, Ren W
Frontiers in immunology 2020;11:1866
Frontiers in immunology 2020;11:1866
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats.
Liu C, Ding R, Huang W, Miao L, Li J, Li Y
Pharmacology 2020;105(3-4):231-242
Pharmacology 2020;105(3-4):231-242
GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer.
Liu L, Pan Y, Ren X, Zeng Z, Sun J, Zhou K, Liang Y, Wang F, Yan Y, Liao W, Ding Y, Liu X, Liang L
American journal of cancer research 2020;10(8):2510-2522
American journal of cancer research 2020;10(8):2510-2522
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
Zhang L, Yang Y, Liao Z, Liu Q, Lei X, Li M, Saijilafu, Zhang Z, Hong D, Zhu M, Li B, Yang H, Chen J
Theranostics 2020;10(15):6638-6660
Theranostics 2020;10(15):6638-6660
Dynorphin activation of kappa opioid receptor promotes microglial polarization toward M2 phenotype via TLR4/NF-κB pathway.
Liu L, Xu Y, Dai H, Tan S, Mao X, Chen Z
Cell & bioscience 2020;10:42
Cell & bioscience 2020;10:42
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies.
Wu Y, Wang Z, Fu X, Lin Z, Yu K
International immunopharmacology 2020 Sep;86:106713
International immunopharmacology 2020 Sep;86:106713
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis.
Yu J, Sun G, Chen Y, Li L, Wang H, Tu D, Li L, Meng Z, Wang Y
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Journal of cardiovascular pharmacology 2020 Sep;76(3):329-336
Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells.
Kang N, Cao S, Jiang B, Zhang Q, Donkor PO, Zhu Y, Qiu F, Gao X
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104885
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104885
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis.
Zhang Y, Chen Y, Li B, Ding P, Jin D, Hou S, Cai X, Sheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110408
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Chen Y, Lu Y, Pei C, Liang J, Ding P, Chen S, Hou SZ
European journal of pharmacology 2020 Sep 15;883:173358
European journal of pharmacology 2020 Sep 15;883:173358
Copper induces oxidative stress with triggered NF-κB pathway leading to inflammatory responses in immune organs of chicken.
Yang F, Liao J, Yu W, Pei R, Qiao N, Han Q, Hu L, Li Y, Guo J, Pan J, Tang Z
Ecotoxicology and environmental safety 2020 Sep 1;200:110715
Ecotoxicology and environmental safety 2020 Sep 1;200:110715
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
TLR4 contributes to the damage of cartilage and subchondral bone in discectomy-induced TMJOA mice.
Liu X, Cai HX, Cao PY, Feng Y, Jiang HH, Liu L, Ke J, Long X
Journal of cellular and molecular medicine 2020 Oct;24(19):11489-11499
Journal of cellular and molecular medicine 2020 Oct;24(19):11489-11499
Potential hazardous effects of printing room PM2.5 exposure include promotion of lung inflammation and subsequent injury.
Zou C, Yang H, Cui L, Cao X, Huang H, Chen T
Molecular medicine reports 2020 Oct;22(4):3213-3224
Molecular medicine reports 2020 Oct;22(4):3213-3224
(-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels.
Li L, Chu X, Yao Y, Cao J, Li Q, Ma H
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11229-11241
Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer.
Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, Chen J, Yang F, Siebert HC, Zheng X
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
Journal of agricultural and food chemistry 2020 Oct 7;68(40):11182-11196
CP-25 improves nephropathy in collagen-induced arthritis rats by inhibiting the renal inflammatory response.
Wang C, Wei X, Wu Y, Tang H, Wang B, Wang Y, Sun W, Asenso J, Xiao F, Wei W
International immunopharmacology 2020 Nov;88:106997
International immunopharmacology 2020 Nov;88:106997
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation.
Zheng L, Tang X, Lu M, Sun S, Xie S, Cai J, Zan J
International immunopharmacology 2020 Nov;88:106937
International immunopharmacology 2020 Nov;88:106937
PDLIM2 protects articular chondrocytes from lipopolysaccharide-induced apoptosis, degeneration and inflammatory injury through down-regulation of nuclear factor (NF)-κB signaling.
Guo Q, Xu J, Shi Q, Wu S
International immunopharmacology 2020 Nov;88:106883
International immunopharmacology 2020 Nov;88:106883
Panax notoginseng saponin R1 modulates TNF-α/NF-κB signaling and attenuates allergic airway inflammation in asthma.
Xue K, Ruan L, Hu J, Fu Z, Tian D, Zou W
International immunopharmacology 2020 Nov;88:106860
International immunopharmacology 2020 Nov;88:106860
Proteases Activate Pregnancy Neutrophils by a Protease-Activated Receptor 1 Pathway: Epigenetic Implications for Preeclampsia.
Walsh SW, Nugent WH, Al Dulaimi M, Washington SL, Dacha P, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Reproductive sciences (Thousand Oaks, Calif.) 2020 Nov;27(11):2115-2127
Role of TLR4/MyD88/NF-κB signaling in the contrast-induced injury of renal tubular epithelial cells.
Wang X, Zhou J, Yang J, Wang S, Yang L
Experimental and therapeutic medicine 2020 Nov;20(5):115
Experimental and therapeutic medicine 2020 Nov;20(5):115
Protective effect of astaxanthin against SnS(2) nanoflowers induced testes toxicity by suppressing RIPK1-RIPK3-MLKL signaling in mice.
Yuan L, Liang P, Qu Y, An T, Wang J, Deng X, Bai L, Shen P, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Nov;145:111736
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Jiang T, Zhou J, Liu W, Tao W, He J, Jin W, Guo H, Yang N, Li Y
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.
Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Zhang Z, Wang Y, Shan Y, Yin W
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Inhibition of notch enhances the anti-atherosclerotic effects of LXR agonists while reducing fatty liver development in ApoE-deficient mice.
Hao Y, Wang X, Zhang F, Wang M, Wang Y, Wang H, Du Y, Wang T, Fu F, Gao Z, Zhang L
Toxicology and applied pharmacology 2020 Nov 1;406:115211
Toxicology and applied pharmacology 2020 Nov 1;406:115211
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y
International journal of oncology 2020 May;56(5):1162-1174
International journal of oncology 2020 May;56(5):1162-1174
Pin1 promotes pancreatic cancer progression and metastasis by activation of NF-κB-IL-18 feedback loop.
Sun Q, Fan G, Zhuo Q, Dai W, Ye Z, Ji S, Xu W, Liu W, Hu Q, Zhang Z, Liu M, Yu X, Xu X, Qin Y
Cell proliferation 2020 May;53(5):e12816
Cell proliferation 2020 May;53(5):e12816
Annexin-1 Mimetic Peptide Ac2-26 Suppresses Inflammatory Mediators in LPS-Induced Astrocytes and Ameliorates Pain Hypersensitivity in a Rat Model of Inflammatory Pain.
Luo Z, Wang H, Fang S, Li L, Li X, Shi J, Zhu M, Tan Z, Lu Z
Cellular and molecular neurobiology 2020 May;40(4):569-585
Cellular and molecular neurobiology 2020 May;40(4):569-585
Porcine parvovirus nonstructural protein NS1 activates NF-κB and it involves TLR2 signaling pathway.
Jin X, Yuan Y, Zhang C, Zhou Y, Song Y, Wei Z, Zhang G
Journal of veterinary science 2020 May;21(3):e50
Journal of veterinary science 2020 May;21(3):e50
Protective effect of ginsenoside Rg5 against kidney injury via inhibition of NLRP3 inflammasome activation and the MAPK signaling pathway in high-fat diet/streptozotocin-induced diabetic mice.
Zhu Y, Zhu C, Yang H, Deng J, Fan D
Pharmacological research 2020 May;155:104746
Pharmacological research 2020 May;155:104746
Ruscogenin alleviates LPS-induced pulmonary endothelial cell apoptosis by suppressing TLR4 signaling.
Wu Y, Wang Y, Gong S, Tang J, Zhang J, Li F, Yu B, Zhang Y, Kou J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109868
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109868
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, Tan P, Xia X, Du Y, Fu W
Life sciences 2020 May 15;249:117517
Life sciences 2020 May 15;249:117517
Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.
Wang Q, Tang Q, Zhao L, Zhang Q, Wu Y, Hu H, Liu L, Liu X, Zhu Y, Guo A, Yang X
Cancer biology & medicine 2020 May 15;17(2):401-417
Cancer biology & medicine 2020 May 15;17(2):401-417
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype.
Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, Han S, Yin J, He X
Cell death & disease 2020 May 15;11(5):377
Cell death & disease 2020 May 15;11(5):377
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl(4)-induced liver injury mouse model.
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, Liu A, Chen X, Wei L, Zhou L, Zhao J
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
American journal of physiology. Endocrinology and metabolism 2020 May 1;318(5):E817-E829
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Pyrroloquinoline quinone attenuates isoproterenol hydrochloride‑induced cardiac hypertrophy in AC16 cells by inhibiting the NF‑κB signaling pathway.
Wen J, Shen J, Zhou Y, Zhao X, Dai Z, Jin Y
International journal of molecular medicine 2020 Mar;45(3):873-885
International journal of molecular medicine 2020 Mar;45(3):873-885
Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition.
Deng X, Zheng C, Wang S, Yang R, Liu Z, Chen T
Oncology reports 2020 Mar;43(3):986-998
Oncology reports 2020 Mar;43(3):986-998
Influence of feature rankers in the construction of molecular activity prediction models.
Cerruela-García G, Pérez-Parra Toledano J, de Haro-García A, García-Pedrajas N
Journal of computer-aided molecular design 2020 Mar;34(3):305-325
Journal of computer-aided molecular design 2020 Mar;34(3):305-325
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Wei K, Dai J, Wang Z, Pei Y, Chen Y, Ding Y, Ding Q, Ahati P, Zhou X, Wang H, Fang H
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Experimental biology and medicine (Maywood, N.J.) 2020 Mar;245(6):532-541
Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation.
Zhang Y, Cui N, Zheng G
Oncology letters 2020 Mar;19(3):1975-1984
Oncology letters 2020 Mar;19(3):1975-1984
The Immunomodulatory Effects and Mechanisms of Tim-3 Action in the Early Stage of Mice with Severe Acute Pancreatitis.
Lin M, Huang J, Chen WC, Fan ZN, Qin X
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
Iranian journal of immunology : IJI 2020 Mar;17(1):52-63
RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
Yang B, Liu Y, Cui Y, Song D, Zhang G, Ma S, Liu Y, Chen M, Chen F, Wang H, Wang J
PLoS pathogens 2020 Mar;16(3):e1008387
PLoS pathogens 2020 Mar;16(3):e1008387
IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway.
Cai H, Yan L, Liu N, Xu M, Cai H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109790
Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway.
Hsu YH, Chen YC, Chen YW, Chiu TH, Kuo YT, Chen CH
Metabolism: clinical and experimental 2020 Mar;104:154143
Metabolism: clinical and experimental 2020 Mar;104:154143
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, Lin X, Dou R, Bai J, Xiang Z, Huang S, Liu K, Xiong B
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study.
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, Liao X, Pan J
Food & function 2020 Mar 26;11(3):2654-2666
Food & function 2020 Mar 26;11(3):2654-2666
Monocyte-derived extracellular vesicles upon treated by palmitate promote endothelial migration and monocytes attachment to endothelial cells.
Gao W, Guo X, Wang Y, Jian D, Li M
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Biochemical and biophysical research communications 2020 Mar 12;523(3):685-691
Suppression of high-mobility group box 1 ameliorates xerostomia in a Sjögren syndrome-triggered mouse model.
Wang D, Zhou M, Wang Y, Sun S
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Canadian journal of physiology and pharmacology 2020 Jun;98(6):351-356
Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.
Liu Z, Wang P, Lu S, Guo R, Gao W, Tong H, Yin Y, Han X, Liu T, Chen X, Zhu MX, Yang Z
Cell calcium 2020 Jun;88:102198
Cell calcium 2020 Jun;88:102198
Tle1 attenuates hepatic ischemia/reperfusion injury by suppressing NOD2/NF-κB signaling.
Chen W, Zheng D, Mou T, Pu J, Dai J, Huang Z, Luo Y, Zhang Y, Wu Z
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1176-1182
Bioscience, biotechnology, and biochemistry 2020 Jun;84(6):1176-1182
Jmjd3 is involved in the susceptibility to depression induced by maternal separation via enhancing the neuroinflammation in the prefrontal cortex and hippocampus of male rats.
Wang R, Wang W, Xu J, Liu D, Wu H, Qin X, Jiang H, Pan F
Experimental neurology 2020 Jun;328:113254
Experimental neurology 2020 Jun;328:113254
Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.
Yang C, Lan R, Wang X, Zhao Q, Li X, Bi J, Wang J, Yang G, Lin Y, Liu J, Yin G
Virus research 2020 Jun;282:197956
Virus research 2020 Jun;282:197956
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Wu CC, Chen YR, Lu DH, Hsu LH, Yang KC, Sumi S
Regenerative therapy 2020 Jun;14:177-183
Regenerative therapy 2020 Jun;14:177-183
Dendrobium officinale polysaccharides protected against ethanol-induced acute liver injury in vivo and in vitro via the TLR4/NF-κB signaling pathway.
Yang K, Zhan L, Lu T, Zhou C, Chen X, Dong Y, Lv G, Chen S
Cytokine 2020 Jun;130:155058
Cytokine 2020 Jun;130:155058
Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression.
Luo M, Luo S, Cheng Z, Yang X, Lv D, Li X, Guo Y, Li C, Yan J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110083
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, Li Z, Cheng J, Guan S, Sun S, Chu L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110047
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway.
Li X, Wei R, Wang M, Ma L, Zhang Z, Chen L, Guo Q, Guo S, Zhu S, Zhang S, Min L
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Molecular therapy oncolytics 2020 Jun 26;17:371-383
Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway.
Sun S, Ji Z, Fu J, Wang XF, Zhang LS
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Environmental science and pollution research international 2020 Jul;27(21):26163-26171
Porcine RACK1 negatively regulates the infection of classical swine fever virus and the NF-κB activation in PK-15 cells.
Wang X, Gao L, Yang X, Zuo Q, Lan R, Li M, Yang C, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Jul;246:108711
Veterinary microbiology 2020 Jul;246:108711
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE(2)/MMP-2 in Mouse Offspring.
Ma T, Zhou Y, Xia Y, Meng X, Jin H, Wang B, Chen Y, Qiu J, Wu J, Ding J, Han X, Li D
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Environmental science & technology 2020 Jul 7;54(13):8245-8258
The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.
Wu K, Yuan Y, Yu H, Dai X, Wang S, Sun Z, Wang F, Fei H, Lin Q, Jiang H, Chen T
Blood 2020 Jul 23;136(4):501-515
Blood 2020 Jul 23;136(4):501-515
Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers.
Yang L, Cao H, Sun D, Lin L, Zheng WP, Shen ZY, Song HL
Stem cells and development 2020 Jul 1;29(13):835-852
Stem cells and development 2020 Jul 1;29(13):835-852
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice.
Liu Y, Zhao J, Lu M, Wang H, Tang F
Canadian journal of physiology and pharmacology 2020 Jan;98(1):6-14
Canadian journal of physiology and pharmacology 2020 Jan;98(1):6-14
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
Zhang Q, Zhao S, Zheng W, Fu H, Wu T, Hu F
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, Lin J
Molecular and cellular biochemistry 2020 Jan;463(1-2):203-210
Molecular and cellular biochemistry 2020 Jan;463(1-2):203-210
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, Sun S, Chu X, Cheng J, Guan S, Li Z, Chu L
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jan;393(1):13-23
MiR-22 restrains proliferation of rheumatoid arthritis by targeting IL6R and may be concerned with the suppression of NF-κB pathway.
Yang QY, Yang KP, Li ZZ
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
The Kaohsiung journal of medical sciences 2020 Jan;36(1):20-26
Protease Amplification of the Inflammatory Response Induced by Commensal Bacteria: Implications for Racial Disparity in Term and Preterm Birth.
Walsh SW, Nugent WH, Alam SMK, Washington SL, Teves M, Jefferson KK, Strauss JF 3rd
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jan;27(1):246-259
MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection.
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, Wang Y, Huang Y, Lin L, Chen S, Xu W, Tong L, Wu X, Zhao D, Zhang F, Zhao W, Zhong Z
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
RNA (New York, N.Y.) 2020 Jan;26(1):91-100
Hic-5 deficiency protects cerulein-induced chronic pancreatitis via down-regulation of the NF-κB (p65)/IL-6 signalling pathway.
Chen H, Tan P, Qian B, Du Y, Wang A, Shi H, Huang Z, Huang S, Liang T, Fu W
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Journal of cellular and molecular medicine 2020 Jan;24(2):1488-1503
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization.
Wu B, Song Q, Zhang Y, Wang C, Yang M, Zhang J, Han W, Jiang P
Lipids in health and disease 2020 Jan 8;19(1):4
Lipids in health and disease 2020 Jan 8;19(1):4
Dopamine attenuates lipopolysaccharide-induced expression of proinflammatory cytokines by inhibiting the nuclear translocation of NF-κB p65 through the formation of dopamine quinone in microglia.
Yoshioka Y, Sugino Y, Shibagaki F, Yamamuro A, Ishimaru Y, Maeda S
European journal of pharmacology 2020 Jan 5;866:172826
European journal of pharmacology 2020 Jan 5;866:172826
The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation.
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R
Aging 2020 Jan 29;12(2):1685-1703
Aging 2020 Jan 29;12(2):1685-1703
Ginsenoside Rk1 induces apoptosis and downregulates the expression of PD-L1 by targeting the NF-κB pathway in lung adenocarcinoma.
Hu M, Yang J, Qu L, Deng X, Duan Z, Fu R, Liang L, Fan D
Food & function 2020 Jan 29;11(1):456-471
Food & function 2020 Jan 29;11(1):456-471
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Wu S, Zhao M, Sun Y, Xie M, Le K, Xu M, Huang C
Life sciences 2020 Jan 15;241:117115
Life sciences 2020 Jan 15;241:117115
Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide.
Zhang H, Chen Y, Chen Y, Li Y, Jia P, Ji S, Zhou Y, Wang T
Journal of animal science 2020 Jan 1;98(1)
Journal of animal science 2020 Jan 1;98(1)
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Baicalein attenuates the neuroinflammation in LPS-activated BV-2 microglial cells through suppression of pro-inflammatory cytokines, COX2/NF-κB expressions and regulation of metabolic abnormality.
Yan JJ, Du GH, Qin XM, Gao L
International immunopharmacology 2020 Feb;79:106092
International immunopharmacology 2020 Feb;79:106092
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells.
He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, Yue Z
Molecular medicine reports 2020 Feb;21(2):597-606
Molecular medicine reports 2020 Feb;21(2):597-606
Network pharmacology based research into the effect and mechanism of Xijiao Dihuang decoction against sepsis.
Lu J, Yan J, Yan J, Zhang L, Chen M, Chen Q, Cheng L, Li P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109777
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109777
N-WASP knockdown upregulates inflammatory cytokines expression in human gingival fibroblasts.
Wang Y, Kang W, Shang L, Song A, Ge S
Archives of oral biology 2020 Feb;110:104605
Archives of oral biology 2020 Feb;110:104605
Silencing of PTX3 alleviates LPS-induced inflammatory pain by regulating TLR4/NF-κB signaling pathway in mice.
Qi S, Zhao F, Li Z, Liang F, Yu S
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells.
Li S, Li Q, Zhu Y, Hu W
Experimental cell research 2020 Feb 1;387(1):111745
Experimental cell research 2020 Feb 1;387(1):111745
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways.
Zeng Q, Zeng Y, Nie X, Guo Y, Zhan Y
Planta medica 2020 Dec;86(18):1401-1410
Planta medica 2020 Dec;86(18):1401-1410
Protective effect of hydroxysafflor yellow A on dopaminergic neurons against 6-hydroxydopamine, activating anti-apoptotic and anti-neuroinflammatory pathways.
Yang X, Li Y, Chen L, Xu M, Wu J, Zhang P, Nel D, Sun B
Pharmaceutical biology 2020 Dec;58(1):686-694
Pharmaceutical biology 2020 Dec;58(1):686-694
Hepatoprotective effects of Camellia nitidissima aqueous ethanol extract against CCl(4)-induced acute liver injury in SD rats related to Nrf2 and NF-κB signalling.
Zhang X, Feng J, Su S, Huang L
Pharmaceutical biology 2020 Dec;58(1):239-246
Pharmaceutical biology 2020 Dec;58(1):239-246
Pre-ischemic renal lavage protects against renal ischemia-reperfusion injury by attenuation of local and systemic inflammatory responses.
Guo S, Zhang F, Chen Y, Chen Y, Shushakova N, Yao Y, Zeng R, Li J, Lu X, Chen R, Haller H, Gueler F, Xu G, Rong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16307-16318
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Zhao Z, Li J, Zheng B, Liang Y, Shi J, Zhang J, Han X, Chu L, Chu X, Gao Y
Molecular medicine reports 2020 Dec;22(6):5271-5281
Molecular medicine reports 2020 Dec;22(6):5271-5281
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Xue Y, Li M, Xue Y, Jin W, Han X, Zhang J, Chu X, Li Z, Chu L
Molecular medicine reports 2020 Dec;22(6):4663-4674
Molecular medicine reports 2020 Dec;22(6):4663-4674
Hepatitis B virus core protein promotes the expression of neuraminidase 1 to facilitate hepatocarcinogenesis.
Kong F, Li N, Tu T, Tao Y, Bi Y, Yuan D, Zhang N, Yang X, Kong D, You H, Zheng K, Tang R
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1602-1617
Laboratory investigation; a journal of technical methods and pathology 2020 Dec;100(12):1602-1617
Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport.
Tian M, Chen J, Wu Z, Song H, Yang F, Cui C, Chen F, Zhang S, Guan W
Animals : an open access journal from MDPI 2020 Dec 26;11(1)
Animals : an open access journal from MDPI 2020 Dec 26;11(1)
Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids.
Jiang Y, Gong H, Jiang S, She C, Cao Y
The Science of the total environment 2020 Dec 15;748:141384
The Science of the total environment 2020 Dec 15;748:141384
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Wang X, Yu H, Wang C, Liu Y, You J, Wang P, Xu G, Shen H, Yao H, Lan X, Zhao R, Wu X, Zhang G
Toxicology 2020 Dec 15;446:152625
Toxicology 2020 Dec 15;446:152625
Akebia Saponin D suppresses inflammation in chondrocytes via the NRF2/HO-1/NF-κB axis and ameliorates osteoarthritis in mice.
Gu M, Jin J, Ren C, Chen X, Gao W, Wang X, Wu Y, Tian N, Pan Z, Wu A, Zhou Y, Zhang X
Food & function 2020 Dec 1;11(12):10852-10863
Food & function 2020 Dec 1;11(12):10852-10863
Saturated fatty acids activate the inflammatory signalling pathway in Schwann cells: Implication in sciatic nerve injury.
Xu D, Liang J, Cui M, Zhang L, Ren S, Zheng W, Dong X, Zhang B
Scandinavian journal of immunology 2020 Aug;92(2):e12896
Scandinavian journal of immunology 2020 Aug;92(2):e12896
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Wang W, Yang R, Zhang M, Li J, Peng J, Xu M, Zhao Y, Li H, Pan X
Inflammation 2020 Aug;43(4):1312-1322
Inflammation 2020 Aug;43(4):1312-1322
Neferine Inhibits Expression of Inflammatory Mediators and Matrix Degrading Enzymes in IL-1β-Treated Rat Chondrocytes via Suppressing MAPK and NF-κB Signaling Pathways.
Ni B, Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, You H
Inflammation 2020 Aug;43(4):1209-1221
Inflammation 2020 Aug;43(4):1209-1221
Schisandrin B improves cerebral ischemia and reduces reperfusion injury in rats through TLR4/NF-κB signaling pathway inhibition.
Fan X, Elkin K, Shi Y, Zhang Z, Cheng Y, Gu J, Liang J, Wang C, Ji X
Neurological research 2020 Aug;42(8):693-702
Neurological research 2020 Aug;42(8):693-702
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Anti-inflammatory effect of Ganluyin, a Chinese classic prescription, in chronic pharyngitis rat model.
Chen YH, Luo R, Lei SS, Li B, Zhou FC, Wang HY, Chen X, He X, Wang YZ, Zhan LH, Lu TT, Su J, Yu QX, Li B, Lv GY, Chen SH
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
BMC complementary medicine and therapies 2020 Aug 28;20(1):265
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.
Wu L, Liu X, Huang Y, Lu C, Zhou J, Ren P, Huang X
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
ACS chemical neuroscience 2020 Aug 19;11(16):2472-2481
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
The response of phenoloxidase to cadmium-disturbed hepatopancreatic immune-related molecules in freshwater crayfish Procambarus clarkii.
Wei K, Wei Y, Song C
Fish & shellfish immunology 2020 Apr;99:190-198
Fish & shellfish immunology 2020 Apr;99:190-198
Therapeutic effects of recombinant human brain natriuretic peptide on sepsis-associated encephalopathy in mice.
Li N, Zhang EF, Zhang J, Zhang L, Liu YE, Jin HX, Gao Y, Hou LC
International immunopharmacology 2020 Apr;81:106280
International immunopharmacology 2020 Apr;81:106280
Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models.
Wang M, Zhang J, Zhao H, Wan D, Jiang Z
International immunopharmacology 2020 Apr;81:106205
International immunopharmacology 2020 Apr;81:106205
p-Coumaric Acid Attenuates IL-1β-Induced Inflammatory Responses and Cellular Senescence in Rat Chondrocytes.
Huang X, You Y, Xi Y, Ni B, Chu X, Zhang R, You H
Inflammation 2020 Apr;43(2):619-628
Inflammation 2020 Apr;43(2):619-628
HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway.
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, Wang Y, Yan W, Zhou Z, Yang H
Neurotoxicity research 2020 Apr;37(4):913-925
Neurotoxicity research 2020 Apr;37(4):913-925
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Tian C, Gao F, Li X, Li Z
Experimental and molecular pathology 2020 Apr;113:104373
Experimental and molecular pathology 2020 Apr;113:104373
A Combination of Formic Acid and Monolaurin Attenuates Enterotoxigenic Escherichia coli Induced Intestinal Inflammation in Piglets by Inhibiting the NF-κB/MAPK Pathways with Modulation of Gut Microbiota.
Ren C, Wang Y, Lin X, Song H, Zhou Q, Xu W, Shi K, Chen J, Song J, Chen F, Zhang S, Guan W
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4155-4165
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Liu Q, Guo X, Huang Z, He Q, Zhu D, Zhang S, Peng Z, Che Y, Feng X
Behavioural brain research 2020 Apr 6;383:112539
Behavioural brain research 2020 Apr 6;383:112539
Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice.
Huang Y, Qiu L, Mi X, Zhang Z, Xu D, Tao X, Xing K, Wu Q, Wei H
Food & function 2020 Apr 30;11(4):3459-3470
Food & function 2020 Apr 30;11(4):3459-3470
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580
Journal of ethnopharmacology 2020 Apr 24;252:112580
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, Pan J, Xue R, Cao G, Tang J, Song X, Hu X, Gong C
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.
Xiong M, Chen L, Zhou L, Ding Y, Kazobinka G, Chen Z, Hou T
Theranostics 2019;9(24):7156-7167
Theranostics 2019;9(24):7156-7167
Copy number gain of ZEB1 mediates a double-negative feedback loop with miR-33a-5p that regulates EMT and bone metastasis of prostate cancer dependent on TGF-β signaling.
Dai Y, Wu Z, Lang C, Zhang X, He S, Yang Q, Guo W, Lai Y, Du H, Peng X, Ren D
Theranostics 2019;9(21):6063-6079
Theranostics 2019;9(21):6063-6079
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Zhao J, Gao W, Cai X, Xu J, Zou D, Li Z, Hu B, Zheng Y
Theranostics 2019;9(10):2843-2855
Theranostics 2019;9(10):2843-2855
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
Peng P, Chen T, Wang Q, Zhang Y, Zheng F, Huang S, Tang Y, Yang C, Ding W, Ren D, Huang Z, Guo Y
Oncology research and treatment 2019;42(4):165-185
Oncology research and treatment 2019;42(4):165-185
MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways.
Liu Z, Tao B, Fan S, Pu Y, Xia H, Xu L
Oxidative medicine and cellular longevity 2019;2019:8948657
Oxidative medicine and cellular longevity 2019;2019:8948657
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Wang G, Xu B, Shi F, Du M, Li Y, Yu T, Chen L
Oxidative medicine and cellular longevity 2019;2019:7850324
Oxidative medicine and cellular longevity 2019;2019:7850324
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, Zheng T, Pu S, Xia X, Fu W
Oxidative medicine and cellular longevity 2019;2019:3765898
Oxidative medicine and cellular longevity 2019;2019:3765898
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways.
Jin Y, Li Y, Wang X, Yang Y
Cancer cell international 2019;19:220
Cancer cell international 2019;19:220
HIV-1-infected cell-derived exosomes promote the growth and progression of cervical cancer.
Li H, Chi X, Li R, Ouyang J, Chen Y
International journal of biological sciences 2019;15(11):2438-2447
International journal of biological sciences 2019;15(11):2438-2447
Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway.
Li Y, Huang T, Fu Y, Wang T, Zhao T, Guo S, Sun Y, Yang Y, Li C
PloS one 2019;14(9):e0215886
PloS one 2019;14(9):e0215886
ETA-mediated anti-TNF-α therapy ameliorates the phenotype of PCOS model induced by letrozole.
Lang Q, Yidong X, Xueguang Z, Sixian W, Wenming X, Tao Z
PloS one 2019;14(6):e0217495
PloS one 2019;14(6):e0217495
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity.
Khan MW, Zhao P, Khan A, Raza F, Raza SM, Sarfraz M, Chen Y, Li M, Yang T, Ma X, Xiang G
International journal of nanomedicine 2019;14:3753-3771
International journal of nanomedicine 2019;14:3753-3771
Exosomes Derived From Bone Marrow Mesenchymal Stem Cells Inhibit Complement Activation In Rats With Spinal Cord Injury.
Zhao C, Zhou X, Qiu J, Xin D, Li T, Chu X, Yuan H, Wang H, Wang Z, Wang D
Drug design, development and therapy 2019;13:3693-3704
Drug design, development and therapy 2019;13:3693-3704
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, Liu J
International journal of clinical and experimental pathology 2019;12(3):867-875
International journal of clinical and experimental pathology 2019;12(3):867-875
Hydrocortisone Suppresses Early Paraneoplastic Inflammation And Angiogenesis To Attenuate Early Hepatocellular Carcinoma Progression In Rats.
Liu X, Cui H, Niu H, Wang L, Li X, Sun J, Wei Q, Dong J, Liu L, Xian CJ
OncoTargets and therapy 2019;12:9481-9493
OncoTargets and therapy 2019;12:9481-9493
L-Cysteine-Derived H(2)S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice.
Zhou X, Chu X, Xin D, Li T, Bai X, Qiu J, Yuan H, Liu D, Wang D, Wang Z
Frontiers in molecular neuroscience 2019;12:58
Frontiers in molecular neuroscience 2019;12:58
ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer.
Li W, Li S, Yang J, Cui C, Yu M, Zhang Y
OncoTargets and therapy 2019;12:3753-3763
OncoTargets and therapy 2019;12:3753-3763
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism.
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and therapy 2019;12:2397-2408
OncoTargets and therapy 2019;12:2397-2408
Monitoring the Early Antiproliferative Effect of the Analgesic-Antitumor Peptide, BmK AGAP on Breast Cancer Using Intravoxel Incoherent Motion With a Reduced Distribution of Four b-Values.
Doudou NR, Kampo S, Liu Y, Ahmmed B, Zeng D, Zheng M, Mohamadou A, Wen QP, Wang S
Frontiers in physiology 2019;10:708
Frontiers in physiology 2019;10:708
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Lin Z, Wu D, Huang L, Jiang C, Pan T, Kang X, Pan J
Frontiers in pharmacology 2019;10:570
Frontiers in pharmacology 2019;10:570
Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes.
Tu C, Huang X, Xiao Y, Song M, Ma Y, Yan J, You H, Wu H
Frontiers in pharmacology 2019;10:41
Frontiers in pharmacology 2019;10:41
Gardenia Decoction Prevent Intestinal Mucosal Injury by Inhibiting Pro-inflammatory Cytokines and NF-κB Signaling.
Cui Y, Wang Q, Wang M, Jia J, Wu R
Frontiers in pharmacology 2019;10:180
Frontiers in pharmacology 2019;10:180
Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway.
Zhang H, Liu M, Zhang Y, Li X
Frontiers in pharmacology 2019;10:175
Frontiers in pharmacology 2019;10:175
The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro.
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, Lu J, Bai L
Frontiers in physiology 2019;10:1060
Frontiers in physiology 2019;10:1060
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, Zhang B, Chen X
Frontiers in pharmacology 2019;10:1030
Frontiers in pharmacology 2019;10:1030
Correction to: Protective effects of dioscin against alcohol‑induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2019 Sep;93(9):2713
Archives of toxicology 2019 Sep;93(9):2713
Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization.
Lu H, Cheng S, Wu C, Zheng S, Hong W, Liu L, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2019 Sep;62:152976
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
Chen T, Wang Y, Xu Z, Zou X, Wang P, Ou X, Li Y, Peng T, Chen D, Li M, Cai M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1.
Ding XF, Liang HY, Sun JY, Liu SH, Kan QC, Wang LX, Sun TW
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Journal of cellular physiology 2019 Sep;234(9):16582-16591
Liquiritigenin inhibits IL-1β-induced inflammation and cartilage matrix degradation in rat chondrocytes.
Tu C, Ma Y, Song M, Yan J, Xiao Y, Wu H
European journal of pharmacology 2019 Sep 5;858:172445
European journal of pharmacology 2019 Sep 5;858:172445
Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel.
Li S, Yao M, Niu C, Liu D, Tang Z, Gu C, Zhao H, Ke J, Wu S, Wang X, Wu F
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Biochemical and biophysical research communications 2019 Sep 3;516(4):1066-1072
Vanillic acid attenuates cartilage degeneration by regulating the MAPK and PI3K/AKT/NF-κB pathways.
Huang X, Xi Y, Mao Z, Chu X, Zhang R, Ma X, Ni B, Cheng H, You H
European journal of pharmacology 2019 Sep 15;859:172481
European journal of pharmacology 2019 Sep 15;859:172481
Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer.
Fu Z, Lin L, Liu S, Qin M, He S, Zhu L, Huang J
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 11;25:6836-6845
Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.
Wang L, Qiu JG, He J, Liu WJ, Ge X, Zhou FM, Huang YX, Jiang BH, Liu LZ
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Toxicology and applied pharmacology 2019 Sep 1;378:114603
Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway.
Sun LJ, Qiao W, Xiao YJ, Cui L, Wang X, Ren WD
International immunopharmacology 2019 Oct;75:105782
International immunopharmacology 2019 Oct;75:105782
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, Zheng L, Zhou X, Fu H, Zhou D, Chen Y
International immunopharmacology 2019 Oct;75:105768
International immunopharmacology 2019 Oct;75:105768
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Xing Y, Zhang Z, Chi F, Zhou Y, Ren S, Zhao Z, Zhu Y, Piao D
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Dioscin attenuates Bleomycin-Induced acute lung injury via inhibiting the inflammatory response in mice.
Wu ZL, Wang J
Experimental lung research 2019 Oct;45(8):236-244
Experimental lung research 2019 Oct;45(8):236-244
Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer.
Yang J, Zeng Z, Qiao L, Jiang X, Ma J, Wang J, Ye S, Ma Q, Wei J, Wu M, Huang X, Ma D, Gao Q
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Molecular cancer research : MCR 2019 Oct;17(10):2015-2028
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
Wei F, Jiang Z, Sun H, Pu J, Sun Y, Wang M, Tong Q, Bi Y, Ma X, Gao GF, Liu J
PLoS pathogens 2019 Oct;15(10):e1008062
PLoS pathogens 2019 Oct;15(10):e1008062
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414
Pharmacological research 2019 Oct;148:104414
FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation.
Zang YH, Chen D, Zhou B, Chen AD, Wang JJ, Gao XY, Chen Q, Li YH, Kang YM, Zhu GQ
Vascular pharmacology 2019 Oct;121:106579
Vascular pharmacology 2019 Oct;121:106579
Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages.
Zhao J, Cao J, Yu L, Ma H
Molecular immunology 2019 Oct;114:114-122
Molecular immunology 2019 Oct;114:114-122
γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways.
Shu G, Qiu Y, Hao J, Fu Q, Deng X
Food & function 2019 Oct 16;10(10):6858-6872
Food & function 2019 Oct 16;10(10):6858-6872
Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop.
Liang S, Wang ZG, Zhang ZZ, Chen K, Lv ZT, Wang YT, Cheng P, Sun K, Yang Q, Chen AM
Aging 2019 Oct 11;11(19):8664-8680
Aging 2019 Oct 11;11(19):8664-8680
Light-induced Nrf2(-/-) mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel.
Wang K, Zheng M, Lester KL, Han Z
Scientific reports 2019 Oct 10;9(1):14573
Scientific reports 2019 Oct 10;9(1):14573
Synthesis and biological evaluation of (1,2,4)triazole[4,3-a]pyridine derivatives as potential therapeutic agents for concanavalin A-induced hepatitis.
Shi Y, Wang Q, Rong J, Ren J, Song X, Fan X, Shen M, Xia Y, Wang N, Liu Z, Hu Q, Ye T, Yu L
European journal of medicinal chemistry 2019 Oct 1;179:182-195
European journal of medicinal chemistry 2019 Oct 1;179:182-195
TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.
Wu X, Kong Q, Zhan L, Qiu Z, Huang Q, Song X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2019 Nov;68(11):981-992
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2019 Nov;68(11):981-992
Neuroprotection of Andrographolide Against Microglia-Mediated Inflammatory Injury and Oxidative Damage in PC12 Neurons.
Xu Y, Tang D, Wang J, Wei H, Gao J
Neurochemical research 2019 Nov;44(11):2619-2630
Neurochemical research 2019 Nov;44(11):2619-2630
Effect of Intranasal Instillation of Lipopolysaccharide on Lung Development and Its Related Mechanism in Newborn Mice.
You Y, Guo C, Zhang H, Deng S, Tang J, Xu L, Deng C, Gong F
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2019 Nov;39(11):684-693
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2019 Nov;39(11):684-693
Nonviral Delivery of GRIM-19 Gene Inhibits Tumor Growth with Reduced Local and Systemic Complications.
Xu Y, Wang X, Guo B, Wang D, Kalvakolanu DV, Chen X, Tang J, Zhang L, Yang Q
Human gene therapy 2019 Nov;30(11):1419-1430
Human gene therapy 2019 Nov;30(11):1419-1430
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
Wu L, Wang Y, Chi G, Shen B, Tian Y, Li Z, Han L, Zhang Q, Feng H
Journal of cellular physiology 2019 Nov;234(11):19785-19798
Journal of cellular physiology 2019 Nov;234(11):19785-19798
Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway.
Yang L, Hong Q, Xu SG, Kuang XY, Di GH, Liu GY, Wu J, Shao ZM, Yu SJ
Molecular medicine reports 2019 Nov;20(5):4045-4258
Molecular medicine reports 2019 Nov;20(5):4045-4258
Repression of eEF2K transcription by NF-κB tunes translation elongation to inflammation and dsDNA-sensing.
Bianco C, Thompson L, Mohr I
Proceedings of the National Academy of Sciences of the United States of America 2019 Nov 5;116(45):22583-22590
Proceedings of the National Academy of Sciences of the United States of America 2019 Nov 5;116(45):22583-22590
Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1β Upregulation in Porcine Alveolar Macrophage.
Yang S, Liu B, Yin S, Shang Y, Zhang X, Khan MUZ, Liu X, Cai J
Viruses 2019 Nov 3;11(11)
Viruses 2019 Nov 3;11(11)
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Gao S, Xu T, Guo H, Deng Q, Xun C, Liang W, Sheng W
Life sciences 2019 Nov 15;237:116978
Life sciences 2019 Nov 15;237:116978
Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets.
Wang XC, Zhang YF, Cao L, Zhu L, Huang YY, Chen XF, Chu XY, Zhu DF, Ur Rahman S, Feng SB, Li Y, Wu JJ
Toxins 2019 Nov 14;11(11)
Toxins 2019 Nov 14;11(11)
SPOP inhibits mice pancreatic stellate cell activation by promoting FADD degradation in cerulein-induced chronic pancreatitis.
Tan P, Wang A, Chen H, Du Y, Qian B, Shi H, Zhang Y, Xia X, Fu W
Experimental cell research 2019 Nov 1;384(1):111606
Experimental cell research 2019 Nov 1;384(1):111606
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, Li S, Wu R, Yang H, Lian S
Brain research 2019 Nov 1;1722:146354
Brain research 2019 Nov 1;1722:146354
Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.
Shi H, Yao R, Lian S, Liu P, Liu Y, Yang YY, Yang H, Li S
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Stress (Amsterdam, Netherlands) 2019 May;22(3):366-376
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFβ/Smad3 and NF-κB signalling in a mouse model of hypertension.
Ding H, Zhou Y, Huang H
Clinical and experimental pharmacology & physiology 2019 Mar;46(3):246-254
Clinical and experimental pharmacology & physiology 2019 Mar;46(3):246-254
NF-κB and Poly (ADP-ribose) Polymerase 1 Form a Positive Feedback Loop that Regulates DNA Repair in Acute Myeloid Leukemia Cells.
Li D, Luo Y, Chen X, Zhang L, Wang T, Zhuang Y, Fan Y, Xu J, Chen Y, Wu L
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Molecular cancer research : MCR 2019 Mar;17(3):761-772
Betulinic acid suppresses breast cancer aerobic glycolysis via caveolin-1/NF-κB/c-Myc pathway.
Jiao L, Wang S, Zheng Y, Wang N, Yang B, Wang D, Yang D, Mei W, Zhao Z, Wang Z
Biochemical pharmacology 2019 Mar;161:149-162
Biochemical pharmacology 2019 Mar;161:149-162
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X
Pharmacological research 2019 Mar;141:114-122
Pharmacological research 2019 Mar;141:114-122
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
COMMD7 Regulates NF-κB Signaling Pathway in Hepatocellular Carcinoma Stem-like Cells.
Zheng L, You N, Huang X, Gu H, Wu K, Mi N, Li J
Molecular therapy oncolytics 2019 Mar 29;12:112-123
Molecular therapy oncolytics 2019 Mar 29;12:112-123
Mucin 1 downregulation impairs the anti-necroptotic effects of glucocorticoids in human bronchial epithelial cells.
Zhang H, Liu Q, Kong L, Xu S
Life sciences 2019 Mar 15;221:168-177
Life sciences 2019 Mar 15;221:168-177
In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways.
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, Liu K, Lu T, He C
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway.
Li YM, Zhang J, Su LJ, Kellum JA, Peng ZY
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Biochimica et biophysica acta. Molecular basis of disease 2019 Mar 1;1865(3):558-569
Conjugated Linoleic Acid Ameliorates High Fructose-Induced Hyperuricemia and Renal Inflammation in Rats via NLRP3 Inflammasome and TLR4 Signaling Pathway.
Tan J, Wan L, Chen X, Li X, Hao X, Li X, Li J, Ding H
Molecular nutrition & food research 2019 Jun;63(12):e1801402
Molecular nutrition & food research 2019 Jun;63(12):e1801402
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13
Toxicology 2019 Jun 15;422:1-13
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Effect of Astragalus membranaceus in Ovalbumin-Induced Allergic Rhinitis Mouse Model.
Bing Z, Jin-Tao D, Feng L, Ba L, Ya-Feng L, Shi-Xi L
American journal of rhinology & allergy 2019 Jul;33(4):420-432
American journal of rhinology & allergy 2019 Jul;33(4):420-432
Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals.
Tian L, Su CP, Wang Q, Wu FJ, Bai R, Zhang HM, Liu JY, Lu WJ, Wang W, Lan F, Guo SZ
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
Journal of cellular and molecular medicine 2019 Jul;23(7):4666-4678
GABA(B) receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.
Liu F, Zhang YY, Song N, Lin J, Liu MK, Huang CL, Zhou C, Wang H, Wang M, Shen JF
Brain research bulletin 2019 Jul;149:240-250
Brain research bulletin 2019 Jul;149:240-250
Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome.
Sun P, Sun N, Yin W, Sun Y, Fan K, Guo J, Khan A, He Y, Li H
Veterinary research 2019 Jul 12;50(1):53
Veterinary research 2019 Jul 12;50(1):53
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK.
Wang Y, Wang X, Zhou X, Zhu Z, Yang J, Liu F
International journal of molecular medicine 2019 Jan;43(1):177-184
International journal of molecular medicine 2019 Jan;43(1):177-184
SND1 promotes the proliferation of osteosarcoma cells by upregulating COX‑2/PGE2 expression via activation of NF‑κB.
Zhou M, Wang A, Yin B, Wu D, Han S, Zhang W, Liu J, Sun K
Oncology reports 2019 Jan;41(1):579-589
Oncology reports 2019 Jan;41(1):579-589
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Zhong KL, Lu MY, Liu F, Mei Y, Zhang XJ, Zhang H, Zan J, Sun XO, Tan W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis.
Zheng L, Han X, Hu Y, Zhao X, Yin L, Xu L, Qi Y, Xu Y, Han X, Liu K, Peng J
Pharmacological research 2019 Jan;139:431-439
Pharmacological research 2019 Jan;139:431-439
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, Xu Z, Yang F, Zhong G, Liu F, Cheng F, Chu M, Lin J
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.
Xin H, Wang C, Liu Z
BMC cancer 2019 Jan 8;19(1):30
BMC cancer 2019 Jan 8;19(1):30
Star-related lipid transfer protein 10 (STARD10): a novel key player in alcohol-induced breast cancer progression.
Floris A, Luo J, Frank J, Zhou J, Orrù S, Biancolella M, Pucci S, Orlandi A, Campagna P, Balzano A, Ramani K, Tomasi ML
Journal of experimental & clinical cancer research : CR 2019 Jan 5;38(1):4
Journal of experimental & clinical cancer research : CR 2019 Jan 5;38(1):4
Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.
Hwang WL, Lan HY, Cheng WC, Huang SC, Yang MH
Journal of hematology & oncology 2019 Jan 25;12(1):10
Journal of hematology & oncology 2019 Jan 25;12(1):10
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure.
Xu B, Zang SC, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM, Lian S
Brain, behavior, and immunity 2019 Feb;76:223-235
Brain, behavior, and immunity 2019 Feb;76:223-235
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Zhang WY, Guo YJ, Han WX, Yang MQ, Wen LP, Wang KY, Jiang P
International immunopharmacology 2019 Feb;67:138-144
International immunopharmacology 2019 Feb;67:138-144
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Liu X, Sun H
Inflammation 2019 Feb;42(1):64-80
Inflammation 2019 Feb;42(1):64-80
Silencing of LncRNA steroid receptor RNA activator attenuates polycystic ovary syndrome in mice.
Li Y, Zhao W, Wang H, Chen C, Zhou D, Li S, Zhang X, Zhao H, Zhou D, Chen B
Biochimie 2019 Feb;157:48-56
Biochimie 2019 Feb;157:48-56
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.
Jin XH, Jia YS, Shi YH, Li QY, Bao SQ, Lu WP, Tong ZS
Journal of cellular biochemistry 2019 Feb;120(2):1386-1397
Journal of cellular biochemistry 2019 Feb;120(2):1386-1397
The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers.
Yang JW, Murray B, Barbier-Torres L, Liu T, Liu Z, Yang H, Fan W, Wang J, Li Y, Seki E, Mato JM, Lu SC
The Journal of biological chemistry 2019 Feb 8;294(6):1984-1996
The Journal of biological chemistry 2019 Feb 8;294(6):1984-1996
Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner.
Huang XT, Liu W, Zhou Y, Hao CX, Zhou Y, Zhang CY, Sun CC, Luo ZQ, Tang SY
International journal of molecular medicine 2019 Dec;44(6):2213-2222
International journal of molecular medicine 2019 Dec;44(6):2213-2222
Olean-28,13b-olide 2 plays a role in cisplatin-mediated apoptosis and reverses cisplatin resistance in human lung cancer through multiple signaling pathways.
Zhu B, Ren C, Du K, Zhu H, Ai Y, Kang F, Luo Y, Liu W, Wang L, Xu Y, Jiang X, Zhang Y
Biochemical pharmacology 2019 Dec;170:113642
Biochemical pharmacology 2019 Dec;170:113642
Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate.
Huang Q, Ouyang Z, Tan Y, Wu H, Liu Y
Acta biomaterialia 2019 Dec;100:415-426
Acta biomaterialia 2019 Dec;100:415-426
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
miR-204-5p Represses Bone Metastasis via Inactivating NF-κB Signaling in Prostate Cancer.
Wa Q, Huang S, Pan J, Tang Y, He S, Fu X, Peng X, Chen X, Yang C, Ren D, Huang Y, Liao Z, Huang S, Zou C
Molecular therapy. Nucleic acids 2019 Dec 6;18:567-579
Molecular therapy. Nucleic acids 2019 Dec 6;18:567-579
Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome.
Hu Y, Li Q, Pan Y, Xu L
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Molecules (Basel, Switzerland) 2019 Dec 3;24(23)
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, Zhang X
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
Polychlorinated Biphenyl Quinone Promotes Macrophage-Derived Foam Cell Formation.
Yang B, Wang Y, Qin Q, Xia X, Liu Z, Song E, Song Y
Chemical research in toxicology 2019 Dec 16;32(12):2422-2432
Chemical research in toxicology 2019 Dec 16;32(12):2422-2432
Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis.
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H
Aging 2019 Dec 16;11(24):12532-12545
Aging 2019 Dec 16;11(24):12532-12545
Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway.
Wang X, Zhang Y, Zhao J, Cao L, Zhu L, Huang Y, Chen X, Rahman SU, Feng S, Li Y, Wu J
Toxins 2019 Dec 16;11(12)
Toxins 2019 Dec 16;11(12)
KRAB-Zinc Finger Protein ZNF268a Deficiency Attenuates the Virus-Induced Pro-Inflammatory Response by Preventing IKK Complex Assembly.
Liu Y, Yin W, Wang J, Lei Y, Sun G, Li W, Huang Z, Guo M
Cells 2019 Dec 10;8(12)
Cells 2019 Dec 10;8(12)
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
He S, Yu Q, He Y, Hu R, Xia S, He J
Poultry science 2019 Dec 1;98(12):6378-6387
Poultry science 2019 Dec 1;98(12):6378-6387
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, Fang S, Li M
Neuroscience 2019 Dec 1;422:99-118
Neuroscience 2019 Dec 1;422:99-118
Effects of antisense lncRNA PCBP1-AS1 on biological behaviors of vulvar squamous carcinoma cells by regulating TRAF5 and NF-κB expression.
Wang H, Ouyang L, Gao S
Translational cancer research 2019 Aug;8(4):1578-1590
Translational cancer research 2019 Aug;8(4):1578-1590
JLP-centrosome is essential for the microtubule-mediated nucleocytoplasmic transport induced by extracellular stimuli.
Lee CM, Aizawa K, Jiang J, Kung SKP, Jain R
Science advances 2019 Aug;5(8):eaav0318
Science advances 2019 Aug;5(8):eaav0318
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
Fu J, Li G, Wu X, Zang B
Inflammation 2019 Aug;42(4):1276-1286
Inflammation 2019 Aug;42(4):1276-1286
microRNA-98 protects sepsis mice from cardiac dysfunction, liver and lung injury by negatively regulating HMGA2 through inhibiting NF-κB signaling pathway.
Zhu J, Lin X, Yan C, Yang S, Zhu Z
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1948-1964
Cell cycle (Georgetown, Tex.) 2019 Aug;18(16):1948-1964
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, Zuo Q, Zhou Y, Cao Z, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway.
Peng C, Ding X, Zhu L, He M, Shu Y, Zhang Y, Li Y, Wang X, Feng S, Li J, Wu J
Journal of agricultural and food chemistry 2019 Aug 14;67(32):9009-9021
Journal of agricultural and food chemistry 2019 Aug 14;67(32):9009-9021
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2019 Aug 1;10(8):5240-5241
Food & function 2019 Aug 1;10(8):5240-5241
Quercetin reduces Streptococcus suis virulence by inhibiting suilysin activity and inflammation.
Li G, Shen X, Wei Y, Si X, Deng X, Wang J
International immunopharmacology 2019 Apr;69:71-78
International immunopharmacology 2019 Apr;69:71-78
Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion.
Li HB
Heliyon 2019 Apr;5(4):e01567
Heliyon 2019 Apr;5(4):e01567
MiR-92a contributes to the cardiovascular disease development in diabetes mellitus through NF-κB and downstream inflammatory pathways.
Wang WY, Zheng YS, Li ZG, Cui YM, Jiang JC
European review for medical and pharmacological sciences 2019 Apr;23(7):3070-3079
European review for medical and pharmacological sciences 2019 Apr;23(7):3070-3079
Downregulation of ENDOCAN in myeloid leukemia cells inhibits proliferation and promotes apoptosis by suppressing nuclear factor‑κB activity.
Sun L, Sun C, Sun J, Yang W
Molecular medicine reports 2019 Apr;19(4):3247-3254
Molecular medicine reports 2019 Apr;19(4):3247-3254
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice.
Xu B, Lian S, Guo JR, Wang JF, Zhang LP, Li SZ, Yang HM
Neuroscience letters 2019 Apr 23;699:97-102
Neuroscience letters 2019 Apr 23;699:97-102
Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease.
Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L
Life sciences 2019 Apr 15;223:158-165
Life sciences 2019 Apr 15;223:158-165
Immunomodulatory effects of an acidic polysaccharide fraction from herbal Gynostemma pentaphyllum tea in RAW264.7 cells.
Ren D, Zhao Y, Zheng Q, Alim A, Yang X
Food & function 2019 Apr 1;10(4):2186-2197
Food & function 2019 Apr 1;10(4):2186-2197
Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation.
Yang L, Guo Y, Huang M, Wu X, Li X, Chen G, Li Y, Bai J
Frontiers in neurology 2018;9:49
Frontiers in neurology 2018;9:49
Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation.
Tian Y, Feng H, Han L, Wu L, Lv H, Shen B, Li Z, Zhang Q, Liu G
Frontiers in immunology 2018;9:147
Frontiers in immunology 2018;9:147
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Liang S, Lv ZT, Zhang JM, Wang YT, Dong YH, Wang ZG, Chen K, Cheng P, Yang Q, Guo FJ, Lu WW, Zhu WT, Chen AM
Frontiers in pharmacology 2018;9:1378
Frontiers in pharmacology 2018;9:1378
Anthraquinone Emodin Inhibits Tumor Necrosis Factor Alpha-Induced Calcification of Human Aortic Valve Interstitial Cells via the NF-κB Pathway.
Xu K, Zhou T, Huang Y, Chi Q, Shi J, Zhu P, Dong N
Frontiers in pharmacology 2018;9:1328
Frontiers in pharmacology 2018;9:1328
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Sun MC, Hou PP, Wang XY, Zhao CH, Cheng BJ, Wang YL, Hao HW, Zhang TH, Ye HQ
Food & nutrition research 2018;62
Food & nutrition research 2018;62
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Shen D, Tian L, Shen T, Sun H, Liu P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Zhao Y, Zheng J, Yu Y, Wang L
BioMed research international 2018;2018:9239354
BioMed research international 2018;2018:9239354
Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes.
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, Fu Y, Yao D, Cao L, Jiang P
Oxidative medicine and cellular longevity 2018;2018:9125601
Oxidative medicine and cellular longevity 2018;2018:9125601
Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.
Luo D, Liu L, Liang FX, Yu ZM, Chen R
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Evidence-based complementary and alternative medicine : eCAM 2018;2018:5302049
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
HIV-1 Tat increases BAG3 via NF-κB signaling to induce autophagy during HIV-associated neurocognitive disorder.
Wu X, Dong H, Ye X, Zhong L, Cao T, Xu Q, Wang J, Zhang Y, Xu J, Wang W, Wei Q, Liu Y, Wang S, Shao Y, Xing H
Cell cycle (Georgetown, Tex.) 2018;17(13):1614-1623
Cell cycle (Georgetown, Tex.) 2018;17(13):1614-1623
The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice.
Cui Y, Wang Y, Li G, Ma W, Zhou XS, Wang J, Liu B
PloS one 2018;13(12):e0209444
PloS one 2018;13(12):e0209444
IRAK-M Deficiency Exacerbates Ischemic Neurovascular Injuries in Experimental Stroke Mice.
Lyu C, Zhang Y, Gu M, Huang Y, Liu G, Wang C, Li M, Chen S, Pan S, Gu Y
Frontiers in cellular neuroscience 2018;12:504
Frontiers in cellular neuroscience 2018;12:504
Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway.
Chen Y, Wang L, Zhang L, Chen B, Yang L, Li X, Li Y, Yu H
Frontiers in cellular neuroscience 2018;12:372
Frontiers in cellular neuroscience 2018;12:372
Clostridium butyricum protects the epithelial barrier by maintaining tight junction protein expression and regulating microflora in a murine model of dextran sodium sulfate-induced colitis.
Li H, Gong Y, Xie Y, Sun Q, Li Y
Scandinavian journal of gastroenterology 2018 Sep;53(9):1031-1042
Scandinavian journal of gastroenterology 2018 Sep;53(9):1031-1042
Resveratrol induces apoptosis in SGC-7901 gastric cancer cells.
Wu X, Xu Y, Zhu B, Liu Q, Yao Q, Zhao G
Oncology letters 2018 Sep;16(3):2949-2956
Oncology letters 2018 Sep;16(3):2949-2956
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose.
Xu B, Lian S, Li SZ, Guo JR, Wang JF, Wang D, Zhang LP, Yang HM
Brain research bulletin 2018 Sep;142:163-175
Brain research bulletin 2018 Sep;142:163-175
StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.
Fukushima M, Dasgupta D, Mauer AS, Kakazu E, Nakao K, Malhi H
The Journal of biological chemistry 2018 Sep 28;293(39):15277-15289
The Journal of biological chemistry 2018 Sep 28;293(39):15277-15289
Polychlorinated Biphenyl Quinones Promotes Breast Cancer Metastasis through Reactive Oxygen Species-Mediated Nuclear Factor κB-Matrix Metalloproteinase Signaling.
Wang Y, Wang Y, Liu Z, Dong W, Yang B, Xia X, Song E, Song Y
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Chemical research in toxicology 2018 Sep 17;31(9):954-963
Protective roles of NRF2 signaling pathway in cobalt chloride-induced hypoxic cytotoxicity in human HaCaT keratinocytes.
Yang B, Cheng H, Wang L, Fu J, Zhang G, Guan D, Qi R, Gao X, Zhao R
Toxicology and applied pharmacology 2018 Sep 15;355:189-197
Toxicology and applied pharmacology 2018 Sep 15;355:189-197
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.
Zhai C, Shi W, Feng W, Zhu Y, Wang J, Li S, Yan X, Wang Q, Zhang Q, Chai L, Li C, Liu P, Li M
Life sciences 2018 Sep 1;208:87-95
Life sciences 2018 Sep 1;208:87-95
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
α7‑nAchR agonist GTS‑21 reduces radiation‑induced lung injury.
Mei Z, Tian X, Chen J, Wang Y, Yao Y, Li X, Yang C, Zhang S, Xie C
Oncology reports 2018 Oct;40(4):2287-2297
Oncology reports 2018 Oct;40(4):2287-2297
Long non-coding RNA FTH1P3 regulated metastasis and invasion of esophageal squamous cell carcinoma through SP1/NF-kB pathway.
Yang L, Sun K, Chu J, Qu Y, Zhao X, Yin H, Ming L, Wan J, He F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1570-1577
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
Jiang Y, Liu J, Zhou Z, Liu K, Liu C
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 2;24:7007-7014
REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis.
Wang S, Lin Y, Yuan X, Li F, Guo L, Wu B
Nature communications 2018 Oct 12;9(1):4246
Nature communications 2018 Oct 12;9(1):4246
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Shi W, Zhai C, Feng W, Wang J, Zhu Y, Li S, Wang Q, Zhang Q, Yan X, Chai L, Liu P, Chen Y, Li M
Life sciences 2018 Oct 1;210:140-149
Life sciences 2018 Oct 1;210:140-149
IL-8 analogue CXCL8 (3-72) K11R/G31P, modulates LPS-induced inflammation via AKT1-NF-kβ and ERK1/2-AP-1 pathways in THP-1 monocytes.
Walana W, Wang JJ, Yabasin IB, Ntim M, Kampo S, Al-Azab M, Elkhider A, Dogkotenge Kuugbee E, Cheng JW, Gordon JR, Li F
Human immunology 2018 Nov;79(11):809-816
Human immunology 2018 Nov;79(11):809-816
HMGB1 knock-down promoting tumor cells viability and arrest pro-apoptotic proteins via Stat3/NFκB in HepG2 cells.
Alduais S, Alduais Y, Wu X, Li H, Mao J
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
BioFactors (Oxford, England) 2018 Nov;44(6):570-576
Inhibition of microRNA-143-3p attenuates myocardial hypertrophy by inhibiting inflammatory response.
Yu B, Zhao Y, Zhang H, Xie D, Nie W, Shi K
Cell biology international 2018 Nov;42(11):1584-1593
Cell biology international 2018 Nov;42(11):1584-1593
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Caffeic acid protects against IL-1β-induced inflammatory responses and cartilage degradation in articular chondrocytes.
Huang X, Xi Y, Pan Q, Mao Z, Zhang R, Ma X, You H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:433-439
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-κB and activation Nrf2 pathway.
Zhang LM, Zhang J, Zhang Y, Wang L, Fei C, Yi ZW, Dong L
Biochemical and biophysical research communications 2018 Nov 2;505(3):837-842
Biochemical and biophysical research communications 2018 Nov 2;505(3):837-842
Macrophages mediate corticotomy-accelerated orthodontic tooth movement.
Wang Y, Zhang H, Sun W, Wang S, Zhang S, Zhu L, Chen Y, Xie L, Sun Z, Yan B
Scientific reports 2018 Nov 14;8(1):16788
Scientific reports 2018 Nov 14;8(1):16788
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
Li B, Li D, Wang Y, Meng X, Sun X, Tian J, Shi L, Ma F
Experimental animals 2018 Nov 1;67(4):451-461
Experimental animals 2018 Nov 1;67(4):451-461
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
Yang B, Song D, Liu Y, Cui Y, Lu G, Di W, Xing H, Ma L, Guo Z, Guan Y, Wang H, Wang J
FEBS letters 2018 May;592(10):1693-1704
FEBS letters 2018 May;592(10):1693-1704
DFMG attenuates the activation of macrophages induced by co‑culture with LPC‑injured HUVE‑12 cells via the TLR4/MyD88/NF‑κB signaling pathway.
Cong L, Yang S, Zhang Y, Cao J, Fu X
International journal of molecular medicine 2018 May;41(5):2619-2628
International journal of molecular medicine 2018 May;41(5):2619-2628
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling.
Huang X, Yue Z, Wu J, Chen J, Wang S, Wu J, Ren L, Zhang A, Deng P, Wang K, Wu C, Ding X, Ye P, Xia J
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1086-1101
Arteriosclerosis, thrombosis, and vascular biology 2018 May;38(5):1086-1101
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694
Food & function 2018 May 23;9(5):2684-2694
Hesperidin suppresses the migration and invasion of non-small cell lung cancer cells by inhibiting the SDF-1/CXCR-4 pathway.
Xia R, Xu G, Huang Y, Sheng X, Xu X, Lu H
Life sciences 2018 May 15;201:111-120
Life sciences 2018 May 15;201:111-120
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Src Promotes Metastasis of Human Non-Small Cell Lung Cancer Cells through Fn14-Mediated NF-κB Signaling.
Wang W, Liu F, Wang C, Wang C, Tang Y, Jiang Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 3;24:1282-1294
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 3;24:1282-1294
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury.
Ling C, Liang J, Zhang C, Li R, Mou Q, Qin J, Li X, Wang J
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Molecules (Basel, Switzerland) 2018 Mar 2;23(3)
Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma.
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, Li J, Peng Q, Ban Y, Zhou Y, Zeng Z, Li X, Xiong W, Li G, Xiang B
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Journal of cellular physiology 2018 Jun;233(6):5002-5013
Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells.
Zhang YY, Zhang Y, Yao YB, Lei XL, Qian ZJ
Marine drugs 2018 Jun 7;16(6)
Marine drugs 2018 Jun 7;16(6)
Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties.
Wang S, Xu M, Li X, Su X, Xiao X, Keating A, Zhao RC
Journal of hematology & oncology 2018 Jun 14;11(1):82
Journal of hematology & oncology 2018 Jun 14;11(1):82
Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.
Cen B, Liao W, Wang Z, Gao L, Wei Y, Huang W, He S, Wang W, Liu X, Pan X, Ji A
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
Molecular therapy. Nucleic acids 2018 Jun 1;11:300-311
JMJD6 exerts function in neuropathic pain by regulating NF‑κB following peripheral nerve injury in rats.
Wen C, Xu M, Mo C, Cheng Z, Guo Q, Zhu X
International journal of molecular medicine 2018 Jul;42(1):633-642
International journal of molecular medicine 2018 Jul;42(1):633-642
BST2 promotes cell proliferation, migration and induces NF-κB activation in gastric cancer.
Liu W, Cao Y, Guan Y, Zheng C
Biotechnology letters 2018 Jul;40(7):1015-1027
Biotechnology letters 2018 Jul;40(7):1015-1027
Isosteviol ameliorates diabetic cardiomyopathy in rats by inhibiting ERK and NF-κB signaling pathways.
Tang SG, Liu XY, Ye JM, Hu TT, Yang YY, Han T, Tan W
The Journal of endocrinology 2018 Jul;238(1):47-60
The Journal of endocrinology 2018 Jul;238(1):47-60
Subcutaneous administration of infliximab-attenuated silica-induced lung fibrosis.
Zhang H, Sui JN, Gao L, Guo J
International journal of occupational medicine and environmental health 2018 Jul 4;31(4):503-515
International journal of occupational medicine and environmental health 2018 Jul 4;31(4):503-515
Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.
Usman MW, Gao J, Zheng T, Rui C, Li T, Bian X, Cheng H, Liu P, Luo F
Cell death & disease 2018 Jul 24;9(8):809
Cell death & disease 2018 Jul 24;9(8):809
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, Ji H, Wang J, Kong F, Zhen L, Li S, Zhang L, Guo J, Yang H
Behavioural brain research 2018 Jul 2;346:1-10
Behavioural brain research 2018 Jul 2;346:1-10
Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.
Yu Y, Zhu W, Liang Q, Liu J, Yang X, Sun G
Journal of neuroimmunology 2018 Jul 15;320:80-86
Journal of neuroimmunology 2018 Jul 15;320:80-86
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma.
Zhang X, Feng H, Li Z, Guo J, Li M
International journal of molecular sciences 2018 Jul 12;19(7)
International journal of molecular sciences 2018 Jul 12;19(7)
Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging.
Wang W, Cai G, Chen X
Experimental gerontology 2018 Jul 1;107:4-10
Experimental gerontology 2018 Jul 1;107:4-10
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Zheng L, Yin L, Xu L, Qi Y, Li H, Xu Y, Han X, Liu K, Peng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:481-488
Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo.
Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z
Journal of cellular physiology 2018 Jan;234(1):777-788
Journal of cellular physiology 2018 Jan;234(1):777-788
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Medical science monitor : international medical journal of experimental and clinical research 2018 Jan 15;24:294-304
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, Qi W, Yang H
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Functional Role of SUV39H1 in Human Renal Tubular Epithelial Cells Under High-glucose Ambiance.
Wang J, Yan W, Peng X, Jiang Y, He L, Peng Y, Chen X, Ye M, Zhuo H
Inflammation 2018 Feb;41(1):1-10
Inflammation 2018 Feb;41(1):1-10
Editor's Highlight: Effects of Intraperitoneal Injection of SnS2 Flowers on Mouse Testicle.
Bai D, Li Q, Xiong Y, Zhao J, Bai L, Shen P, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Feb 1;161(2):388-400
Toxicological sciences : an official journal of the Society of Toxicology 2018 Feb 1;161(2):388-400
Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF‑κb signal pathway.
Zhao X, Yin L, Fang L, Xu L, Sun P, Xu M, Liu K, Peng J
International immunopharmacology 2018 Dec;65:458-469
International immunopharmacology 2018 Dec;65:458-469
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Bidirectional effects of moxifloxacin on the pro‑inflammatory response in lipopolysaccharide‑stimulated mouse peritoneal macrophages.
Qiu Z, Yuan H, Li N, Yang X, Hu X, Su F, Chen B
Molecular medicine reports 2018 Dec;18(6):5399-5408
Molecular medicine reports 2018 Dec;18(6):5399-5408
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Correlation between the expression of IL‑18 and deep venous thrombosis.
Li G, Zhou R, Zhao X, Liu R, Ye C
International journal of molecular medicine 2018 Aug;42(2):883
International journal of molecular medicine 2018 Aug;42(2):883
MEL-pep, an analog of melittin, disrupts cell membranes and reverses 5-fluorouracil resistance in human hepatocellular carcinoma cells.
Ke M, Dong J, Wang Y, Zhang J, Zhang M, Wu Z, Lv Y, Wu R
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
The international journal of biochemistry & cell biology 2018 Aug;101:39-48
NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease.
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, Zhang X, Wen H, Gao C, Liu H
Journal of neuroinflammation 2018 Aug 29;15(1):243
Journal of neuroinflammation 2018 Aug 29;15(1):243
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Xiang L, Xu X, Zhang S, Cai D, Dai X
Free radical biology & medicine 2018 Aug 20;124:205-213
Free radical biology & medicine 2018 Aug 20;124:205-213
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
Shen Y, Qiu T, Liu XH, Zhang L, Wang ZS, Zhou JQ
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
LPS‑induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF‑κB, STAT3 or AP‑1 activation.
Liu X, Yin S, Chen Y, Wu Y, Zheng W, Dong H, Bai Y, Qin Y, Li J, Feng S, Zhao P
Molecular medicine reports 2018 Apr;17(4):5484-5491
Molecular medicine reports 2018 Apr;17(4):5484-5491
Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation.
Wang K, Li YF, Lv Q, Li XM, Dai Y, Wei ZF
Frontiers in pharmacology 2017;8:981
Frontiers in pharmacology 2017;8:981
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Zhang S, Wang Z, Zhu J, Xu T, Zhao Y, Zhao H, Tang F, Li Z, Zhou J, Gao D, Tian X, Yao J
Frontiers in pharmacology 2017;8:976
Frontiers in pharmacology 2017;8:976
TET2 Protects against oxLDL-Induced HUVEC Dysfunction by Upregulating the CSE/H(2)S System.
Peng J, Tang ZH, Ren Z, He B, Zeng Y, Liu LS, Wang Z, Wei DH, Zheng XL, Jiang ZS
Frontiers in pharmacology 2017;8:486
Frontiers in pharmacology 2017;8:486
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, Yin L, Han X, Xu Y, Li H, Sun H, Peng J
Frontiers in pharmacology 2017;8:120
Frontiers in pharmacology 2017;8:120
Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome.
Zuo T, Zhu M, Xu W, Wang Z, Song H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(5):1855-1865
Metformin Sensitizes Non-small Cell Lung Cancer Cells to an Epigallocatechin-3-Gallate (EGCG) Treatment by Suppressing the Nrf2/HO-1 Signaling Pathway.
Yu C, Jiao Y, Xue J, Zhang Q, Yang H, Xing L, Chen G, Wu J, Zhang S, Zhu W, Cao J
International journal of biological sciences 2017;13(12):1560-1569
International journal of biological sciences 2017;13(12):1560-1569
Collagen gel protects L929 cells from TNFα-induced death by activating NF-κB.
Wang HJ, Li MQ, Liu WW, Hayashi T, Fujisaki H, Hattori S, Tashiro SI, Onodera S, Ikejima T
Connective tissue research 2017 Sep;58(5):456-463
Connective tissue research 2017 Sep;58(5):456-463
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Xie X, Li S, Zhu Y, Liu L, Pan Y, Wang J, Shi W, Song Y, Yang L, Gao L, Zang W, Li M
Cell and tissue research 2017 Sep;369(3):527-539
Cell and tissue research 2017 Sep;369(3):527-539
Mechanism of Lycium barbarum polysaccharides on primary cultured rat hippocampal neurons.
Zhao P, Ma NT, Chang RY, Li YX, Hao YJ, Yang WL, Zheng J, Niu Y, Sun T, Yu JQ
Cell and tissue research 2017 Sep;369(3):455-465
Cell and tissue research 2017 Sep;369(3):455-465
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Chen HB, Luo CD, Liang JL, Zhang ZB, Lin GS, Wu JZ, Li CL, Tan LH, Yang XB, Su ZR, Xie JH, Zeng HF
European journal of pharmacology 2017 Sep 15;811:222-231
European journal of pharmacology 2017 Sep 15;811:222-231
Interleukin-17A Plays the Same Role on Mice Acute Lung Injury Respectively Induced by Lipopolysaccharide and Paraquat.
Song HW, Yang C, Liu W, Liu XW, Liu Z, Gao F
Inflammation 2017 Oct;40(5):1509-1519
Inflammation 2017 Oct;40(5):1509-1519
Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses.
Yu J, Zhu YH, Yang GY, Zhang W, Zhou D, Su JH, Wang JF
Veterinary microbiology 2017 Oct;210:91-100
Veterinary microbiology 2017 Oct;210:91-100
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Wang J, Kang L, Song D, Liu L, Yang S, Ma L, Guo Z, Ding H, Wang H, Yang B
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Journal of immunology (Baltimore, Md. : 1950) 2017 Oct 1;199(7):2475-2482
Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways.
Shi YW, Zhang XC, Chen C, Tang M, Wang ZW, Liang XM, Ding F, Wang CP
Brain, behavior, and immunity 2017 Nov;66:244-256
Brain, behavior, and immunity 2017 Nov;66:244-256
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
Peng Z, Gong X, Yang Y, Huang L, Zhang Q, Zhang P, Wan R, Zhang B
International immunopharmacology 2017 Nov;52:281-289
International immunopharmacology 2017 Nov;52:281-289
The effect of Astragaloside IV on ethanol-induced gastric mucosal injury in rats: Involvement of inflammation.
Qin S, Huang K, Fang Z, Yin J, Dai R
International immunopharmacology 2017 Nov;52:211-217
International immunopharmacology 2017 Nov;52:211-217
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
Yang JG, Sun YF, He KF, Ren JG, Liu ZJ, Liu B, Zhang W, Zhao YF
The American journal of pathology 2017 Nov;187(11):2602-2615
The American journal of pathology 2017 Nov;187(11):2602-2615
Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.
Qiu Y, Sui X, Cao S, Li X, Ning Y, Wang S, Yin L, Zhi X
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Journal of cellular biochemistry 2017 Nov;118(11):3932-3942
Comparative study of macrophages in naked mole rats and ICR mice.
Cheng J, Yuan Z, Yang W, Xu C, Cong W, Lin L, Zhao S, Sun W, Bai X, Cui S
Oncotarget 2017 Nov 14;8(57):96924-96934
Oncotarget 2017 Nov 14;8(57):96924-96934
miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation.
Li B, Lu Y, Yu L, Han X, Wang H, Mao J, Shen J, Wang B, Tang J, Li C, Song B
Chemico-biological interactions 2017 Nov 1;277:33-42
Chemico-biological interactions 2017 Nov 1;277:33-42
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Li Y, Xu B, Xu M, Chen D, Xiong Y, Lian M, Sun Y, Tang Z, Wang L, Jiang C, Lin Y
Pharmacological research 2017 May;119:137-148
Pharmacological research 2017 May;119:137-148
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
From the Cover: Activation of NF-κB-Autophagy Axis by 2-Hydroxyethyl Methacrylate Commits Dental Mesenchymal Cells to Apoptosis.
Yu JJ, Zhu LX, Zhang J, Liu S, Lv FY, Cheng X, Liu GJ, Peng B
Toxicological sciences : an official journal of the Society of Toxicology 2017 May 1;157(1):100-111
Toxicological sciences : an official journal of the Society of Toxicology 2017 May 1;157(1):100-111
ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling.
Yang W, Yang S, Zhang M, Gao D, He T, Guo M
Genes & cancer 2017 Mar;8(3-4):528-535
Genes & cancer 2017 Mar;8(3-4):528-535
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.
Chen S, Jiang S, Zheng W, Tu B, Liu S, Ruan H, Fan C
Cell death & disease 2017 Mar 30;8(3):e2710
Cell death & disease 2017 Mar 30;8(3):e2710
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Ren D, Lin D, Alim A, Zheng Q, Yang X
Food & function 2017 Mar 22;8(3):1299-1312
Food & function 2017 Mar 22;8(3):1299-1312
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Li W, Yang X, Zheng T, Xing S, Wu Y, Bian F, Wu G, Li Y, Li J, Bai X, Wu D, Jia X, Wang L, Zhu L, Jin S
Scientific reports 2017 Mar 17;7:44659
Scientific reports 2017 Mar 17;7:44659
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway.
Yu C, Liu Y, Sun L, Wang D, Wang Y, Zhao S, Dai H, Zhao J, Zhang S, Li M, Han Y, Lu S, Dong X, Liu G, Yu S, Li Y
Oncotarget 2017 Jun 6;8(23):37705-37716
Oncotarget 2017 Jun 6;8(23):37705-37716
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Yan XY, Zhang Y, Zhang JJ, Zhang LC, Liu YN, Wu Y, Xue YN, Lu SY, Su J, Sun LK
Cancer science 2017 Jul;108(7):1405-1413
Cancer science 2017 Jul;108(7):1405-1413
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Wu B, Cui J, Yang XM, Liu ZY, Song F, Li L, Jiang JL, Chen ZN
Cell death & disease 2017 Jul 13;8(7):e2925
Cell death & disease 2017 Jul 13;8(7):e2925
Long non-coding RNA HOXA-AS2 promotes proliferation and invasion of breast cancer by acting as a miR-520c-3p sponge.
Fang Y, Wang J, Wu F, Song Y, Zhao S, Zhang Q
Oncotarget 2017 Jul 11;8(28):46090-46103
Oncotarget 2017 Jul 11;8(28):46090-46103
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway.
Ren D, Yang Q, Dai Y, Guo W, Du H, Song L, Peng X
Molecular cancer 2017 Jul 10;16(1):117
Molecular cancer 2017 Jul 10;16(1):117
Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats.
Gu R, Tang W, Lei B, Ding X, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
Investigative ophthalmology & visual science 2017 Jul 1;58(9):3656-3668
Contrast Media-Induced Renal Inflammation Is Mediated Through HMGB1 and Its Receptors in Human Tubular Cells.
Guan XF, Chen QJ, Zuo XC, Guo R, Peng XD, Wang JL, Yin WJ, Li DY
DNA and cell biology 2017 Jan;36(1):67-76
DNA and cell biology 2017 Jan;36(1):67-76
Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway.
Tang J, Dong Q
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
Biochemical and biophysical research communications 2017 Jan 22;482(4):1240-1245
KRAS/NF-κB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis.
Yuan P, He XH, Rong YF, Cao J, Li Y, Hu YP, Liu Y, Li D, Lou W, Liu MF
Cancer research 2017 Jan 1;77(1):100-111
Cancer research 2017 Jan 1;77(1):100-111
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Gu R, Lei B, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, Cao C, Xu R, Wang Y, Ma Y
Molecular immunology 2017 Feb;82:123-136
Molecular immunology 2017 Feb;82:123-136
Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα.
Hu Y, O'Boyle K, Auer J, Raju S, You F, Wang P, Fikrig E, Sutton RE
PLoS pathogens 2017 Feb;13(2):e1006187
PLoS pathogens 2017 Feb;13(2):e1006187
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Calcitriol Ameliorates AngiotensinII-Induced Renal Injury Partly via Upregulating A20.
Zhao H, Xia Y, Gan H
Inflammation 2017 Dec;40(6):1884-1893
Inflammation 2017 Dec;40(6):1884-1893
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, Xing M
Chemosphere 2017 Dec;189:489-497
Chemosphere 2017 Dec;189:489-497
Downregulation of miR-141-3p promotes bone metastasis via activating NF-κB signaling in prostate cancer.
Huang S, Wa Q, Pan J, Peng X, Ren D, Huang Y, Chen X, Tang Y
Journal of experimental & clinical cancer research : CR 2017 Dec 4;36(1):173
Journal of experimental & clinical cancer research : CR 2017 Dec 4;36(1):173
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, Kong F, Xu B, Li S, Yang H
Oncotarget 2017 Dec 29;8(70):115304-115314
Oncotarget 2017 Dec 29;8(70):115304-115314
CAPE-pNO(2) ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z
Oncotarget 2017 Dec 29;8(70):114506-114525
Oncotarget 2017 Dec 29;8(70):114506-114525
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Khan MR, Xiang S, Song Z, Wu M
The EMBO journal 2017 Dec 1;36(23):3483-3500
The EMBO journal 2017 Dec 1;36(23):3483-3500
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Liu CC, Zhang Y, Dai BL, Ma YJ, Zhang Q, Wang Y, Yang H
Molecular medicine reports 2017 Aug;16(2):1369-1375
Molecular medicine reports 2017 Aug;16(2):1369-1375
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Jiang YH, Guo JH, Wu S, Yang CH
Chinese journal of natural medicines 2017 Aug;15(8):606-614
Chinese journal of natural medicines 2017 Aug;15(8):606-614
Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.
Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z
Vascular pharmacology 2017 Apr;91:26-35
Vascular pharmacology 2017 Apr;91:26-35
Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats.
Wang CP, Shi YW, Tang M, Zhang XC, Gu Y, Liang XM, Wang ZW, Ding F
Molecular neurobiology 2017 Apr;54(3):2126-2142
Molecular neurobiology 2017 Apr;54(3):2126-2142
MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-α, by targeting TRAF3.
Zou M, Wang F, Jiang A, Xia A, Kong S, Gong C, Zhu M, Zhou X, Zhu J, Zhu W, Cheng W
Helicobacter 2017 Apr;22(2)
Helicobacter 2017 Apr;22(2)
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Targeting NF-kB signaling with polymeric hybrid micelles that co-deliver siRNA and dexamethasone for arthritis therapy.
Wang Q, Jiang H, Li Y, Chen W, Li H, Peng K, Zhang Z, Sun X
Biomaterials 2017 Apr;122:10-22
Biomaterials 2017 Apr;122:10-22
Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.
Zhao X, Zhao G, Shi Z, Zhou C, Chen Y, Hu B, Yan S
Scientific reports 2017 Apr 5;7:45779
Scientific reports 2017 Apr 5;7:45779
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Chen L, Liu T, Wang Q, Liu J
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
BMC complementary and alternative medicine 2017 Apr 27;17(1):233
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Xu H, Su C, Pearson A, Mody CH, Zheng C
Journal of virology 2017 Apr 1;91(7)
Journal of virology 2017 Apr 1;91(7)
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Xiang H, Wang G, Qu J, Xia S, Tao X, Qi B, Zhang Q, Shang D
Frontiers in pharmacology 2016;7:378
Frontiers in pharmacology 2016;7:378
Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway.
Liu J, Chen Q, Jian Z, Xiong X, Shao L, Jin T, Zhu X, Wang L
BioMed research international 2016;2016:2816056
BioMed research international 2016;2016:2816056
Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol.
Han R, Tang F, Lu M, Xu C, Hu J, Mei M, Wang H
International immunopharmacology 2016 Sep;38:306-12
International immunopharmacology 2016 Sep;38:306-12
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
miR-34a and its novel target, NLRC5, are associated with HPV16 persistence.
Li J, Yu L, Shen Z, Li Y, Chen B, Wei W, Chen X, Wang Q, Tong F, Lou H, Chu M, Wei L
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Oct;44:293-299
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Oct;44:293-299
Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells.
Li K, Li X, Tian J, Wang H, Pan J, Li J
Oncology reports 2016 Oct;36(4):1973-80
Oncology reports 2016 Oct;36(4):1973-80
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Oncology letters 2016 Oct;12(4):2632-2640
Oncology letters 2016 Oct;12(4):2632-2640
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Wang S, Xu H, Xin Y, Li M, Fu W, Wang Y, Lu Z, Yu X, Sui D
European journal of pharmacology 2016 Oct 5;788:335-342
European journal of pharmacology 2016 Oct 5;788:335-342
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Hu Y, Tao X, Han X, Xu L, Yin L, Qi Y, Zhao Y, Xu Y, Wang C, Peng J
Chemico-biological interactions 2016 Oct 25;258:234-44
Chemico-biological interactions 2016 Oct 25;258:234-44
Cleavage and polyadenylation specific factor 4 targets NF-κB/cyclooxygenase-2 signaling to promote lung cancer growth and progression.
Yi C, Wang Y, Zhang C, Xuan Y, Zhao S, Liu T, Li W, Liao Y, Feng X, Hao J, Gao Y, Yu W, Chen Y, Zhang C, Guo W, Tang B, Deng W
Cancer letters 2016 Oct 10;381(1):1-13
Cancer letters 2016 Oct 10;381(1):1-13
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Xu D, Wang H, Zheng W, Gao Y, Wang M, Zhang Y, Gao Q
International journal of biological macromolecules 2016 Nov;92:30-36
International journal of biological macromolecules 2016 Nov;92:30-36
Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro.
Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, Zhang Z, Lin Y, Peng J, Song Z, Wang S, Tang Z
International immunopharmacology 2016 Nov;40:400-409
International immunopharmacology 2016 Nov;40:400-409
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Inhibitory effects of S-allylmercaptocysteine against benzo(a)pyrene-induced precancerous carcinogenesis in human lung cells.
Wang K, Wang Y, Qi Q, Zhang F, Zhang Y, Zhu X, Liu G, Luan Y, Zhao Z, Cai J, Cao J, Li S
International immunopharmacology 2016 May;34:37-43
International immunopharmacology 2016 May;34:37-43
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
Hu QP, Mao DA
BMC neuroscience 2016 May 18;17(1):22
BMC neuroscience 2016 May 18;17(1):22
The role of glycogen synthase kinase-3β (GSK-3β) in endometrial carcinoma: A carcinogenesis, progression, prognosis, and target therapy marker.
Chen S, Sun KX, Liu BL, Zong ZH, Zhao Y
Oncotarget 2016 May 10;7(19):27538-51
Oncotarget 2016 May 10;7(19):27538-51
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, Xu J, Tian D
Scientific reports 2016 Jun 8;6:27597
Scientific reports 2016 Jun 8;6:27597
Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65.
Liu Q, Zhang Z, Zheng Z, Zheng C, Liu Y, Hu Q, Ke X, Wang H
Scientific reports 2016 Jun 22;6:28481
Scientific reports 2016 Jun 22;6:28481
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Zou M, Duan Y, Wang P, Gao R, Chen X, Ou Y, Liang M, Wang Z, Yuan Y, Wang L, Zhu H
Scientific reports 2016 Jun 2;6:27331
Scientific reports 2016 Jun 2;6:27331
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, Xu Y, Wang C, Peng J
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
Yao H, Hu C, Yin L, Tao X, Xu L, Qi Y, Han X, Xu Y, Zhao Y, Wang C, Peng J
International immunopharmacology 2016 Jul;36:132-141
International immunopharmacology 2016 Jul;36:132-141
The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration.
Wu X, Liu W, Duan Z, Gao Y, Li S, Wang K, Song Y, Shao Z, Yang S, Yang C
Scientific reports 2016 Jul 27;6:30563
Scientific reports 2016 Jul 27;6:30563
Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation.
Zhao L, Xu L, Tao X, Han X, Yin L, Qi Y, Peng J
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
Molecules (Basel, Switzerland) 2016 Jul 21;21(7)
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Zhai Y, Wu B, Li J, Yao XY, Zhu P, Chen ZN
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling.
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, Song E, Song Y
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Environmental toxicology and pharmacology 2016 Jan;41:241-50
Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Radiation research 2016 Jan;185(1):77-86
Radiation research 2016 Jan;185(1):77-86
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
The role of STIM1 in the Cr(vi)-induced [Ca(2+)](i) increase and cell injury in L-02 hepatocytes.
Yi X, Zhang Y, Zhong C, Zhong X, Xiao F
Metallomics : integrated biometal science 2016 Dec 7;8(12):1273-1282
Metallomics : integrated biometal science 2016 Dec 7;8(12):1273-1282
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway.
Wang Y, Chen G, Yu X, Li Y, Zhang L, He Z, Zhang N, Yang X, Zhao Y, Li N, Qiu H
Inflammation 2016 Aug;39(4):1503-13
Inflammation 2016 Aug;39(4):1503-13
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, Zhang X, Ye L
Oncogene 2016 Aug 4;35(31):4048-57
Oncogene 2016 Aug 4;35(31):4048-57
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways.
Xu C, Tang F, Lu M, Yang J, Han R, Mei M, Hu J, Zhou M, Wang H
International immunopharmacology 2016 Apr;33:119-27
International immunopharmacology 2016 Apr;33:119-27
Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation.
Wu YQ, Dang RL, Tang MM, Cai HL, Li HD, Liao DH, He X, Cao LJ, Xue Y, Jiang P
Nutrients 2016 Apr 23;8(4):243
Nutrients 2016 Apr 23;8(4):243
Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway.
Li X, Wang S, Zhu R, Li H, Han Q, Zhao RC
Journal of hematology & oncology 2016 Apr 18;9:42
Journal of hematology & oncology 2016 Apr 18;9:42
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Li X, Yang J, Liu D, Li J, Niu K, Feng S, Yokota H, Zhang P
Scientific reports 2016 Apr 18;6:24668
Scientific reports 2016 Apr 18;6:24668
Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Ma Z, Hou T, Shi W, Liu W, He H
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
International journal of molecular sciences 2015 Sep 11;16(9):22062-80
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3β in oral squamous cell carcinoma Tca-8113 cells.
He K, Tong D, Zhang S, Cai D, Wang L, Yang Y, Gao L, Chang S, Guo B, Song T, Li A, Huang C
International journal of oncology 2015 Oct;47(4):1528-36
International journal of oncology 2015 Oct;47(4):1528-36
Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma.
Liu R, Wang W, Dai B, Liu Y, Zhang Y
Molecular medicine reports 2015 Nov;12(5):7735-41
Molecular medicine reports 2015 Nov;12(5):7735-41
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
Han T, Wan Y, Wang J, Zhao P, Yuan Y, Wang L, She Y, Broering R, Lu M, Ye L, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ.
Li Z, Wang Y, Newton IP, Zhang L, Ji P, Li Z
Cellular signalling 2015 Jun;27(6):1237-45
Cellular signalling 2015 Jun;27(6):1237-45
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo.
Shi X, Chen G, Liu X, Qiu Y, Yang S, Zhang Y, Fang X, Zhang C, Liu X
International journal of molecular medicine 2015 Jan;35(1):31-8
International journal of molecular medicine 2015 Jan;35(1):31-8
Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency.
Zhang Y, Li R, Zhu J, Wang Z, Lv S, Xiong JY
The Journal of surgical research 2015 Jan;193(1):399-406
The Journal of surgical research 2015 Jan;193(1):399-406
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
Jin Y, Liu K, Peng J, Wang C, Kang L, Chang N, Sun H
Toxicology letters 2015 Jan 5;232(1):149-58
Toxicology letters 2015 Jan 5;232(1):149-58
Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma.
Wang F, Yang JL, Yu KK, Xu M, Xu YZ, Chen L, Lu YM, Fang HS, Wang XY, Hu ZQ, Li FF, Kan L, Luo J, Wang SY
Molecular cancer 2015 Jan 27;14(1):10
Molecular cancer 2015 Jan 27;14(1):10
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells.
E Q, Tang M, Zhang X, Shi Y, Wang D, Gu Y, Li S, Liang X, Wang Z, Wang C
Cell biology international 2015 Dec;39(12):1418-24
Cell biology international 2015 Dec;39(12):1418-24
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Wang YS, Li YX, Zhao P, Wang HB, Zhou R, Hao YJ, Wang J, Wang SJ, Du J, Ma L, Sun T, Yu JQ
Inflammation 2015 Dec;38(6):2259-68
Inflammation 2015 Dec;38(6):2259-68
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
Zhang F, Zhang Y, Wang K, Zhu X, Lin G, Zhao Z, Li S, Cai J, Cao J
International immunopharmacology 2015 Dec;29(2):326-333
International immunopharmacology 2015 Dec;29(2):326-333
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
Sinomenine sensitizes multidrug-resistant colon cancer cells (Caco-2) to doxorubicin by downregulation of MDR-1 expression.
Liu Z, Duan ZJ, Chang JY, Zhang ZF, Chu R, Li YL, Dai KH, Mo GQ, Chang QY
PloS one 2014;9(6):e98560
PloS one 2014;9(6):e98560
Ethyl pyruvate pretreatment attenuates concanavalin a-induced autoimmune hepatitis in mice.
Shen M, Lu J, Cheng P, Lin C, Dai W, Wang F, Wang C, Zhang Y, Chen K, Xu L, Zhou Y, Guo C
PloS one 2014;9(2):e87977
PloS one 2014;9(2):e87977
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.
Xing S, Yang X, Li W, Bian F, Wu D, Chi J, Xu G, Zhang Y, Jin S
Oxidative medicine and cellular longevity 2014;2014:904834
Oxidative medicine and cellular longevity 2014;2014:904834
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Li W, Wang C, Peng J, Liang J, Jin Y, Liu Q, Meng Q, Liu K, Sun H
Current pharmaceutical biotechnology 2014;15(12):1173-82
Current pharmaceutical biotechnology 2014;15(12):1173-82
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, Hu L, Song E, Song Y
International immunopharmacology 2014 Oct;22(2):293-302
International immunopharmacology 2014 Oct;22(2):293-302
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through Adenosine 5'-monophosphate-activated protein kinase-sirtuin1 pathway.
Jing H, Yao J, Liu X, Fan H, Zhang F, Li Z, Tian X, Zhou Y
The Journal of surgical research 2014 Mar;187(1):252-61
The Journal of surgical research 2014 Mar;187(1):252-61
A caspase-dependent pathway is involved in Wnt/β-catenin signaling promoted apoptosis in Bacillus Calmette-Guerin infected RAW264.7 macrophages.
Wu X, Deng G, Hao X, Li Y, Zeng J, Ma C, He Y, Liu X, Wang Y
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
International journal of molecular sciences 2014 Mar 21;15(3):5045-62
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM
Journal of neuroscience research 2014 Jul;92(7):944-54
Journal of neuroscience research 2014 Jul;92(7):944-54
Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Wang K, Ni L, Wang S, Zheng C
Journal of virology 2014 Jul;88(14):7941-51
Journal of virology 2014 Jul;88(14):7941-51
Colistin-induced nephrotoxicity in mice involves the mitochondrial, death receptor, and endoplasmic reticulum pathways.
Dai C, Li J, Tang S, Li J, Xiao X
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Antimicrobial agents and chemotherapy 2014 Jul;58(7):4075-85
Salvianolic acid B protects against acute ethanol-induced liver injury through SIRT1-mediated deacetylation of p53 in rats.
Li M, Lu Y, Hu Y, Zhai X, Xu W, Jing H, Tian X, Lin Y, Gao D, Yao J
Toxicology letters 2014 Jul 15;228(2):67-74
Toxicology letters 2014 Jul 15;228(2):67-74
Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, Liu R, He L
Scientific reports 2014 Jul 1;4:5518
Scientific reports 2014 Jul 1;4:5518
Interplay between the Notch and PI3K/Akt pathways in high glucose-induced podocyte apoptosis.
Wang XM, Yao M, Liu SX, Hao J, Liu QJ, Gao F
American journal of physiology. Renal physiology 2014 Jan;306(2):F205-13
American journal of physiology. Renal physiology 2014 Jan;306(2):F205-13
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2014 Dec;5(12):3065-3075
Food & function 2014 Dec;5(12):3065-3075
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
Yu H, Zheng L, Yin L, Xu L, Qi Y, Han X, Xu Y, Liu K, Peng J
International immunopharmacology 2014 Apr;19(2):233-44
International immunopharmacology 2014 Apr;19(2):233-44
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Hu L, Li L, Xu D, Xia X, Pi R, Xu D, Wang W, Du H, Song E, Song Y
Chemico-biological interactions 2014 Apr 25;213:51-9
Chemico-biological interactions 2014 Apr 25;213:51-9
14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.
Tang S, Bao H, Zhang Y, Yao J, Yang P, Chen X
PloS one 2013;8(3):e55268
PloS one 2013;8(3):e55268
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
Shen M, Lu J, Dai W, Wang F, Xu L, Chen K, He L, Cheng P, Zhang Y, Wang C, Wu D, Yang J, Zhu R, Zhang H, Zhou Y, Guo C
Mediators of inflammation 2013;2013:461536
Mediators of inflammation 2013;2013:461536
Fluoride-elicited developmental testicular toxicity in rats: roles of endoplasmic reticulum stress and inflammatory response.
Zhang S, Jiang C, Liu H, Guan Z, Zeng Q, Zhang C, Lei R, Xia T, Gao H, Yang L, Chen Y, Wu X, Zhang X, Cui Y, Yu L, Wang Z, Wang A
Toxicology and applied pharmacology 2013 Sep 1;271(2):206-15
Toxicology and applied pharmacology 2013 Sep 1;271(2):206-15
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
Zhang S, Qi Y, Xu Y, Han X, Peng J, Liu K, Sun CK
Neurochemistry international 2013 Nov;63(5):522-32
Neurochemistry international 2013 Nov;63(5):522-32
Salvianolic acid A preconditioning confers protection against concanavalin A-induced liver injury through SIRT1-mediated repression of p66shc in mice.
Xu X, Hu Y, Zhai X, Lin M, Chen Z, Tian X, Zhang F, Gao D, Ma X, Lv L, Yao J
Toxicology and applied pharmacology 2013 Nov 15;273(1):68-76
Toxicology and applied pharmacology 2013 Nov 15;273(1):68-76
Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Zhang S, Lu B, Han X, Xu L, Qi Y, Yin L, Xu Y, Zhao Y, Liu K, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 May;55:60-9
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang R, Cheng B
International journal of oncology 2013 May;42(5):1636-43
International journal of oncology 2013 May;42(5):1636-43
MG132-mediated inhibition of the ubiquitin-proteasome pathway ameliorates cancer cachexia.
Zhang L, Tang H, Kou Y, Li R, Zheng Y, Wang Q, Zhou X, Jin L
Journal of cancer research and clinical oncology 2013 Jul;139(7):1105-15
Journal of cancer research and clinical oncology 2013 Jul;139(7):1105-15
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang K, Wang S, Zheng C
Journal of virology 2013 Dec;87(23):12935-48
Journal of virology 2013 Dec;87(23):12935-48
Isoquercetin protects cortical neurons from oxygen-glucose deprivation-reperfusion induced injury via suppression of TLR4-NF-кB signal pathway.
Wang CP, Li JL, Zhang LZ, Zhang XC, Yu S, Liang XM, Ding F, Wang ZW
Neurochemistry international 2013 Dec;63(8):741-9
Neurochemistry international 2013 Dec;63(8):741-9
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Dong D, Zhang S, Yin L, Tang X, Xu Y, Han X, Qi Y, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:120-30
Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-кB signaling pathway in isoproterenol-induced myocardial hypertrophy.
Yang J, Wang HX, Zhang YJ, Yang YH, Lu ML, Zhang J, Li ST, Zhang SP, Li G
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Journal of ethnopharmacology 2013 Dec 12;150(3):1062-70
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang S, Wang K, Zheng C
Medical microbiology and immunology 2013 Aug;202(4):313-25
Medical microbiology and immunology 2013 Aug;202(4):313-25
Downregulation of nucleoporin 88 and 214 induced by oridonin may protect OCIM2 acute erythroleukemia cells from apoptosis through regulation of nucleocytoplasmic transport of NF-κB.
Yi S, Chen Y, Wen L, Yang L, Cui G
International journal of molecular medicine 2012 Oct;30(4):877-83
International journal of molecular medicine 2012 Oct;30(4):877-83
Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability.
Tian D, Qiu Y, Zhan Y, Li X, Zhi X, Wang X, Yin L, Ning Y
Cardiovascular diabetology 2012 Nov 21;11:144
Cardiovascular diabetology 2012 Nov 21;11:144
Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats.
Yu N, Di Q, Liu H, Hu Y, Jiang Y, Yan YK, Zhang YF, Zhang YD
Mediators of inflammation 2011;2011:670613
Mediators of inflammation 2011;2011:670613
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma.
Gong K, Li W
Free radical biology & medicine 2011 Dec 15;51(12):2259-71
Free radical biology & medicine 2011 Dec 15;51(12):2259-71
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10745-1-AP(p65 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RELA antibody 10745-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-p65 (IP:10745-1-AP, 3ug; Detection:10745-1-AP 1:1000) with HeLa cells lysate 5000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10745-1-AP(p65 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
