9459

antibody from Cell Signaling Technology, Inc

Targeting: EIF4EBP1 4E-BP1, PHAS-I

Western blot (Data presented on provider website)

Antibody Data

Product number

9459

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#9459, RRID:AB_330985

Product name

Phospho-4E-BP1 (Thr37/46) Antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.

Ma D, Yu H, Lin D, Sun Y, Liu L, Liu Y, Dai B, Chen W, Cao J
Journal of cellular physiology 2009 Apr;219(1):31-44

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Isolation of hyperactive mutants of mammalian target of rapamycin.

Ohne Y, Takahara T, Hatakeyama R, Matsuzaki T, Noda M, Mizushima N, Maeda T
The Journal of biological chemistry 2008 Nov 14;283(46):31861-70

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A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells.

Kwiatkowski DJ, Zhang H, Bandura JL, Heiberger KM, Glogauer M, el-Hashemite N, Onda H
Human molecular genetics 2002 Mar 1;11(5):525-34

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mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.

Yu K, Toral-Barza L, Discafani C, Zhang WG, Skotnicki J, Frost P, Gibbons JJ
Endocrine-related cancer 2001 Sep;8(3):249-58

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Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver.

Jiang YP, Ballou LM, Lin RZ
The Journal of biological chemistry 2001 Apr 6;276(14):10943-51