Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN196967 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr45) antibody
- Antibody type
- Polyclonal
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pThr45
- Vial size
- 50 μL
- Storage
- -20°C
- Handling
- Avoid repeated freezing and thawing.
Submitted references Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.
Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG Jr
Genes & development 2004 Dec 1;18(23):2893-904
Genes & development 2004 Dec 1;18(23):2893-904
Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.
Kumar V, Pandey P, Sabatini D, Kumar M, Majumder PK, Bharti A, Carmichael G, Kufe D, Kharbanda S
The EMBO journal 2000 Mar 1;19(5):1087-97
The EMBO journal 2000 Mar 1;19(5):1087-97
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway.
Gingras AC, Kennedy SG, O'Leary MA, Sonenberg N, Hay N
Genes & development 1998 Feb 15;12(4):502-13
Genes & development 1998 Feb 15;12(4):502-13
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