abx015716

EIF4EBP1 antibody from Abbexa
4E-BP1, PHAS-I
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
abx015716
Provider
Abbexa
Product name
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody
Provider product page
Abbexa - abx015716
Antibody type
Monoclonal
Description
4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa).Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1.Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not.Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64.Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µl
Concentration
1 mg/ml
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -