Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- HPA023887 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA023887, RRID:AB_1849226
- Product name
- Anti-FYN
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FYN, Gene description: FYN proto-oncogene, Src family tyrosine kinase, Alternative Gene Names: MGC45350, SLK, SYN, Validated applications: ICC, IHC, WB, Uniprot ID: P06241, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN
Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release
Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF‑7 breast cancer cells
Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease
Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice
Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination.
Kizhatil K, Clark G, Sunderland D, Bhandari A, Horbal L, Balasubramanian R, John S
Nature Communications 2025;16(1)
Nature Communications 2025;16(1)
Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release
Glennon E, Lau D, Gabriele R, Taylor M, Troakes C, Opie-Martin S, Elliott C, Killick R, Hanger D, Perez-Nievas B, Noble W
Brain Communications 2020;2(1)
Brain Communications 2020;2(1)
Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF‑7 breast cancer cells
Li J, Rong M, Dang Y, He R, Lin P, Yang H, Li X, Xiong D, Zhang L, Qin H, Feng C, Chen X, Zhong J, Ma J, Chen G
Molecular Medicine Reports 2019
Molecular Medicine Reports 2019
Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease
Lau D, Hogseth M, Phillips E, O’Neill M, Pooler A, Noble W, Hanger D
Acta Neuropathologica Communications 2016;4(1)
Acta Neuropathologica Communications 2016;4(1)
Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice
Suo M, Wang P, Zhang M
Journal of Neurophysiology 2016;116(2):448-455
Journal of Neurophysiology 2016;116(2):448-455
Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination.
Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, Ito A, Ogata T, Terada N, Tanoue A, Yamauchi J
Molecular biology of the cell 2015 Oct 1;26(19):3489-503
Molecular biology of the cell 2015 Oct 1;26(19):3489-503
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-FYN antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol