626502

antibody from BioLegend

Targeting: FYN MGC45350, SLK, SYN

Immunoprecipitation

Antibody data

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Validation data

Product number: 626502 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#626502, RRID:AB_2278824
Product name: Purified anti-Fyn
Antibody type: Monoclonal
Antigen: Partial recombinant human Fyn (aa 7-176) expressed in E coli
Description: Fyn is a 59 kD protein tyrosine kinase and a member of the src subfamily. There are two reported isoforms of Fyn; FynT found in T cells, B cells and thymocytes, and FynB found in neuronal cells. Fyn has been shown to control cell growth, interact with the p85 subunit of PI3K, control high affinity IgE receptor-mediated mast cell degranulation, and participate in neuronal cell signaling. Fyn can be activated by T cell receptor engagement or anti-CD3 ligation. Fyn is known to be modified by phosphorylation and palmitoylation and has been shown to interact with Fyn binding protein, p85 PI3K, high affinity IgE receptor, and NCAM140. The FYN-59 monoclonal antibody recognizes human and mouse Fyn and has been shown to be useful for Western blotting, immunoprecipitation, and immunohistochemistry.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Upon receipt, store antibody solution undiluted at 4° C.

FYN protein structure - 626502 shown in red.