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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunoprecipitation [1]
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- Product number
- NB500-517 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-517, RRID:AB_10001942
- Product name
- Mouse Monoclonal Fyn Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. The reacts with p59fyn (Fyn), a non receptor protein tyrosine kinase (59 kDa),which belongs to the Src family of cytoplasmic tyrosine kinases.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Regulation of GVBD in mouse oocytes by miR-125a-3p and Fyn kinase through modulation of actin filaments.
Hypoxia-inducible factors enhance glutamate signaling in cancer cells.
Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.
The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization.
Grossman H, Har-Paz E, Gindi N, Levi M, Miller I, Nevo N, Galiani D, Dekel N, Shalgi R
Scientific reports 2017 May 22;7(1):2238
Scientific reports 2017 May 22;7(1):2238
Hypoxia-inducible factors enhance glutamate signaling in cancer cells.
Hu H, Takano N, Xiang L, Gilkes DM, Luo W, Semenza GL
Oncotarget 2014 Oct 15;5(19):8853-68
Oncotarget 2014 Oct 15;5(19):8853-68
Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.
Taniguchi K, Xia L, Goldberg HJ, Lee KW, Shah A, Stavar L, Masson EA, Momen A, Shikatani EA, John R, Husain M, Fantus IG
Diabetes 2013 Nov;62(11):3874-86
Diabetes 2013 Nov;62(11):3874-86
The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization.
Jia R, Pan Q, Ding S, Rong L, Liu SL, Geng Y, Qiao W, Liang C
Journal of virology 2012 Dec;86(24):13697-707
Journal of virology 2012 Dec;86(24):13697-707
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunoprecipitation: Fyn Antibody (FYN-01) [NB500-517] - Immunoprecipitation of Fyn from the lysate of T cells isolated from fresh buffy coats. Western blot was immunostained with anti-Fyn (FYN-01). Lane 1: original lysate of T cells Lane 2-3: Immunoprecipitated material eluted from affinity sorbent (FYN-01 coupled to Sepharose beads). Lanes differ in amount of T cell lysate loaded on the immunosorbent.
