BS4780

antibody from Bioworld Technology, Inc

Targeting: PPP1R14A CPI-17, PPP1INL

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4780 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS4780, RRID:AB_1663130
Product name: CPI 17 (phospho T38) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human CPI-17 around the phosphorylation site of Threonine 38.
Description: CPI-17 is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. CPI-17 was originally identified as a PKC-potentiated inhibitory protein of protein phosphatase-1, which is dominantly expressed in smooth muscle. Phosphorylation at Threonine 38, in vitro, by PKC or Rho-kinase enhances the inhibitory potency toward myosin phosphatase. CPI-17 is also phosphorylated at Threonine 38 by protein kinase N and might be involved in the calcium sensitization of smooth muscle contraction as a downstream effector of Rho and/or arachidonic acid. CPI-17 is dually phosphorylated at Serine 12 and Threonine 38 by a MYPT-associated kinase, M110 kinase.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

PPP1R14A protein structure - BS4780 shown in red.