BS6271

antibody from Bioworld Technology, Inc
Targeting: PRKAA1 AMPKa1
Provider product page for BS6271
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS6271 - Provider product page
Provider
Bioworld Technology, Inc
Product name
AMPKÏ«1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human AMPKÏ«1.
Description
AMPK is a heterotrimeric complex comprising a catalytic Ï« subunit and regulatory ÉÇ and ÎÛ subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKÏ«1 and AMPKÏ«2 genes encode 548 amino acid and 552 amino acid proteins, respectively.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRKAA1 protein structure - BS6271 shown in red.