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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- GTX112998 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX112998, RRID:AB_11162268
- Product name
- AMPK alpha 1 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Storage
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Submitted references PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis.
AMP-activated kinase α2 deficiency protects mice from denervation-induced skeletal muscle atrophy.
Bai-Hu-Jia-Ren-Shen-Tang Decoction Reduces Fatty Liver by Activating AMP-Activated Protein Kinase In Vitro and In Vivo.
The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.
Yang Q, Xu J, Ma Q, Liu Z, Sudhahar V, Cao Y, Wang L, Zeng X, Zhou Y, Zhang M, Xu Y, Wang Y, Weintraub NL, Zhang C, Fukai T, Wu C, Huang L, Han Z, Wang T, Fulton DJ, Hong M, Huo Y
Nature communications 2018 Nov 7;9(1):4667
Nature communications 2018 Nov 7;9(1):4667
AMP-activated kinase α2 deficiency protects mice from denervation-induced skeletal muscle atrophy.
Guo Y, Meng J, Tang Y, Wang T, Wei B, Feng R, Gong B, Wang H, Ji G, Lu Z
Archives of biochemistry and biophysics 2016 Jun 15;600:56-60
Archives of biochemistry and biophysics 2016 Jun 15;600:56-60
Bai-Hu-Jia-Ren-Shen-Tang Decoction Reduces Fatty Liver by Activating AMP-Activated Protein Kinase In Vitro and In Vivo.
Liu HK, Hung TM, Huang HC, Lee IJ, Chang CC, Cheng JJ, Lin LC, Huang C
Evidence-based complementary and alternative medicine : eCAM 2015;2015:651734
Evidence-based complementary and alternative medicine : eCAM 2015;2015:651734
The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.
Huang YH, Huang SW, Hsu YF, Ou G, Huang WJ, Hsu MJ
Scientific reports 2015 Oct 29;5:15900
Scientific reports 2015 Oct 29;5:15900
A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine.
Lee KH, Lo HL, Tang WC, Hsiao HH, Yang PM
Scientific reports 2014 Sep 17;4:6394
Scientific reports 2014 Sep 17;4:6394
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 μg of whole cell lysate) A: NT2D1 B: PC-3 C: U87-MG D: SK-N-SH 7.5% SDS PAGE GTX112998 diluted at 1:1000
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- AMPK alpha 1 antibody immunoprecipitates AMPK alpha 1 protein in IP experiments.IP samples: PC-3 whole cell extractA. Control with 4 £gg of preimmune Rabbit IgGB. Immunoprecipitation of AMPK alpha 1 protein by 4 £gg AMPK alpha 1 antibody (GTX112998)7.5 % SDS-PAGEThe immunoprecipitated AMPK alpha 1 protein was detected by AMPK alpha 1 antibody (GTX112998) diluted at 1:500.[EasyBlot anti-rabbit IgG (GTX221666-01) was used as a secondary reagent]
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human gastric cancer, using AMPK alpha 1(GTX112998) antibody at 1:500 dilution.
