Antibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations [0]
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- Product number
- 66536-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- AMPK Alpha antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated AMPK Alpha antibody (Cat. #66536-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Rat, Mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1H8E1
- Vial size
- 20ul, 150ul
Submitted references Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated cholesterol biosynthesis suppression.
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
Integrated application of metabolomics and RNA-seq reveals thermogenic regulation in goat brown adipose tissues.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Stanniocalcin-1 Protected Astrocytes from Hypoxic Damage Through the AMPK Pathway.
The anti-fatigue activity of corn peptides and their effect on gut bacteria.
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis.
Paeoniflorin suppresses allergic and inflammatory responses by promoting autophagy in rats with urticaria.
Different Proportions of Branched-Chain Amino Acids Modulate Lipid Metabolism in a Finishing Pig Model.
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
In vitro and in vivo synergistic anti-tumor effect of LIN28 inhibitor and metformin in oral squamous cell carcinoma.
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles.
Alpha-enolase (ENO1), identified as an antigen to monoclonal antibody 12C7, promotes the self-renewal and malignant phenotype of lung cancer stem cells by AMPK/mTOR pathway.
Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXRα signal in an AMPK-dependent manner.
Betaine prevented high-fat diet-induced NAFLD by regulating the FGF10/AMPK signaling pathway in ApoE-/- mice.
The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy.
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.
Xu XY, Choi HS, Park SY, Kim JK, Seo KH, Kim H, Kim YJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153870
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153870
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Zou J, Xu MX, Li F, Wang YH, Li XQ, Yu DJ, Ma YJ, Zhang YY, Sun XD
Thoracic cancer 2022 Jan;13(2):190-201
Thoracic cancer 2022 Jan;13(2):190-201
An Inhibitor of NF-κB and an Agonist of AMPK: Network Prediction and Multi-Omics Integration to Derive Signaling Pathways for Acteoside Against Alzheimer's Disease.
Li YQ, Chen Y, Jiang SQ, Shi YY, Jiang XL, Wu SS, Zhou P, Wang HY, Li P, Li F
Frontiers in cell and developmental biology 2021;9:652310
Frontiers in cell and developmental biology 2021;9:652310
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer.
Hu C, Cao Y, Li P, Tang X, Yang M, Gu S, Xiong K, Li T, Xiao T
Journal of oncology 2021;2021:8281718
Journal of oncology 2021;2021:8281718
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway.
Zhang S, Zhang R, Qiao P, Ma X, Lu R, Wang F, Li C, E L, Liu H
Stem cells international 2021;2021:6616240
Stem cells international 2021;2021:6616240
Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration.
Song S, Bao S, Zhang C, Zhang J, Lv J, Li X, Chudhary M, Ren X, Kong L
Oxidative medicine and cellular longevity 2021;2021:5587340
Oxidative medicine and cellular longevity 2021;2021:5587340
Integrated application of metabolomics and RNA-seq reveals thermogenic regulation in goat brown adipose tissues.
Wang Y, Chen X, Fan W, Zhang X, Zhan S, Zhong T, Guo J, Cao J, Li L, Zhang H, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21868
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21868
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
Stanniocalcin-1 Protected Astrocytes from Hypoxic Damage Through the AMPK Pathway.
Sun B, He S, Liu B, Xu G, Guoji E, Feng L, Xu L, Chen D, Zhao W, Chen J, Gao Y, Zhang E
Neurochemical research 2021 Nov;46(11):2948-2957
Neurochemical research 2021 Nov;46(11):2948-2957
The anti-fatigue activity of corn peptides and their effect on gut bacteria.
Feng Z, Wei Y, Xu Y, Zhang R, Li M, Qin H, Gu R, Cai M
Journal of the science of food and agriculture 2021 Nov 28;
Journal of the science of food and agriculture 2021 Nov 28;
WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1.
Zheng Z, Li Y, Fan S, An J, Luo X, Liang M, Zhu F, Huang K
Cell death & disease 2021 Mar 3;12(3):228
Cell death & disease 2021 Mar 3;12(3):228
Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis.
Liu S, Xu A, Gao Y, Xie Y, Liu Z, Sun M, Mao H, Wang X
Journal of nanobiotechnology 2021 Mar 25;19(1):85
Journal of nanobiotechnology 2021 Mar 25;19(1):85
Paeoniflorin suppresses allergic and inflammatory responses by promoting autophagy in rats with urticaria.
Guo J, Peng L, Zeng J, Zhang M, Xu F, Zhang X, Wei Q
Experimental and therapeutic medicine 2021 Jun;21(6):590
Experimental and therapeutic medicine 2021 Jun;21(6):590
Different Proportions of Branched-Chain Amino Acids Modulate Lipid Metabolism in a Finishing Pig Model.
Zhang L, Li F, Guo Q, Duan Y, Wang W, Yang Y, Yin Y, Gong S, Han M, Yin Y
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7037-7048
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7037-7048
A flavonoid-rich Smilax china L. extract prevents obesity by upregulating the adiponectin-receptor/AMPK signalling pathway and modulating the gut microbiota in mice.
Li X, Yang L, Li J, Lin L, Zheng G
Food & function 2021 Jul 5;12(13):5862-5875
Food & function 2021 Jul 5;12(13):5862-5875
In vitro and in vivo synergistic anti-tumor effect of LIN28 inhibitor and metformin in oral squamous cell carcinoma.
Chen H, Sa G, Li L, He S, Wu T
European journal of pharmacology 2021 Jan 15;891:173757
European journal of pharmacology 2021 Jan 15;891:173757
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
American journal of physiology. Heart and circulatory physiology 2021 Jan 1;320(1):H364-H380
Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles.
Gong C, Yu X, Zhang W, Han L, Wang R, Wang Y, Gao S, Yuan Y
Journal of nanobiotechnology 2021 Feb 25;19(1):58
Journal of nanobiotechnology 2021 Feb 25;19(1):58
Alpha-enolase (ENO1), identified as an antigen to monoclonal antibody 12C7, promotes the self-renewal and malignant phenotype of lung cancer stem cells by AMPK/mTOR pathway.
Shu X, Cao KY, Liu HQ, Yu L, Sun LX, Yang ZH, Wu CA, Ran YL
Stem cell research & therapy 2021 Feb 12;12(1):119
Stem cell research & therapy 2021 Feb 12;12(1):119
Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXRα signal in an AMPK-dependent manner.
Chen X, Zou D, Chen X, Wu H, Xu D
Journal of physiology and biochemistry 2021 Aug;77(3):405-417
Journal of physiology and biochemistry 2021 Aug;77(3):405-417
Betaine prevented high-fat diet-induced NAFLD by regulating the FGF10/AMPK signaling pathway in ApoE-/- mice.
Chen W, Zhang X, Xu M, Jiang L, Zhou M, Liu W, Chen Z, Wang Y, Zou Q, Wang L
European journal of nutrition 2021 Apr;60(3):1655-1668
European journal of nutrition 2021 Apr;60(3):1655-1668
The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy.
Yu S, Li Y, Zhao H, Wang Q, Chen P
Frontiers in physiology 2020;11:539
Frontiers in physiology 2020;11:539
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway.
Luo J, Tang C, Chen X, Ren Z, Qu H, Chen R, Tong Z
International journal of environmental research and public health 2020 Mar 19;17(6)
International journal of environmental research and public health 2020 Mar 19;17(6)
QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.
Wang X, Zhao L, Ajay AK, Jiao B, Zhang X, Wang C, Gao X, Yuan Z, Liu H, Liu WJ
Frontiers in physiology 2019;10:1224
Frontiers in physiology 2019;10:1224
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