Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN151706 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (AA 350-400) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Epitope
- AA 350-400
- Vial size
- 0.1 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Satellite cells derived from obese humans with type 2 diabetes and differentiated into myocytes in vitro exhibit abnormal response to IL-6.
AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation.
AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress.
Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy.
Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells.
alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments.
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.
Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats.
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity.
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells.
Scheele C, Nielsen S, Kelly M, Broholm C, Nielsen AR, Taudorf S, Pedersen M, Fischer CP, Pedersen BK
PloS one 2012;7(6):e39657
PloS one 2012;7(6):e39657
AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation.
Föller M, Jaumann M, Dettling J, Saxena A, Pakladok T, Munoz C, Ruth P, Sopjani M, Seebohm G, Rüttiger L, Knipper M, Lang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Oct;26(10):4243-53
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 Oct;26(10):4243-53
AMPKalpha1 deletion shortens erythrocyte life span in mice: role of oxidative stress.
Wang S, Dale GL, Song P, Viollet B, Zou MH
The Journal of biological chemistry 2010 Jun 25;285(26):19976-85
The Journal of biological chemistry 2010 Jun 25;285(26):19976-85
Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy.
Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Oct;57(10):963-71
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Oct;57(10):963-71
Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells.
Qin S, Ni M, De Vries GW
Investigative ophthalmology & visual science 2008 Mar;49(3):1274-81
Investigative ophthalmology & visual science 2008 Mar;49(3):1274-81
alpha2 But not alpha1 AMP-activated protein kinase mediates oxidative stress-induced inhibition of retinal pigment epithelium cell phagocytosis of photoreceptor outer segments.
Qin S, De Vries GW
The Journal of biological chemistry 2008 Mar 14;283(11):6744-51
The Journal of biological chemistry 2008 Mar 14;283(11):6744-51
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.
Gauthier MS, Miyoshi H, Souza SC, Cacicedo JM, Saha AK, Greenberg AS, Ruderman NB
The Journal of biological chemistry 2008 Jun 13;283(24):16514-24
The Journal of biological chemistry 2008 Jun 13;283(24):16514-24
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.
Hou X, Xu S, Maitland-Toolan KA, Sato K, Jiang B, Ido Y, Lan F, Walsh K, Wierzbicki M, Verbeuren TJ, Cohen RA, Zang M
The Journal of biological chemistry 2008 Jul 18;283(29):20015-26
The Journal of biological chemistry 2008 Jul 18;283(29):20015-26
Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats.
Cammisotto PG, Londono I, Gingras D, Bendayan M
American journal of physiology. Renal physiology 2008 Apr;294(4):F881-9
American journal of physiology. Renal physiology 2008 Apr;294(4):F881-9
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.
Zang M, Xu S, Maitland-Toolan KA, Zuccollo A, Hou X, Jiang B, Wierzbicki M, Verbeuren TJ, Cohen RA
Diabetes 2006 Aug;55(8):2180-91
Diabetes 2006 Aug;55(8):2180-91
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity.
Doi M, Yamaoka I, Nakayama M, Mochizuki S, Sugahara K, Yoshizawa F
The Journal of nutrition 2005 Sep;135(9):2103-8
The Journal of nutrition 2005 Sep;135(9):2103-8
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells.
Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA
The Journal of biological chemistry 2004 Nov 12;279(46):47898-905
The Journal of biological chemistry 2004 Nov 12;279(46):47898-905
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- WB
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC