ABIN965547

antibody from antibodies-online

Targeting: PRKAA1 AMPKa1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965547

Provider

antibodies-online

Product name

anti-Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1) (pThr174) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human AMPK1 around the phosphorylation site of threonine 174 (L-R-TP-S-C).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pThr174

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.

Hurley RL, Anderson KA, Franzone JM, Kemp BE, Means AR, Witters LA
The Journal of biological chemistry 2005 Aug 12;280(32):29060-6

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade.

Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D
Current biology : CB 2003 Nov 11;13(22):2004-8

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Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression.

da Silva Xavier G, Leclerc I, Salt IP, Doiron B, Hardie DG, Kahn A, Rutter GA
Proceedings of the National Academy of Sciences of the United States of America 2000 Apr 11;97(8):4023-8