Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB12800 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12800, RRID:AB_10553392
- Product name
- NCK1/NCK2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant His fusion protein corresponding to human NCK1/NCK2.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100 uL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress.
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network.
Latreille M, Larose L
The Journal of biological chemistry 2006 Sep 8;281(36):26633-44
The Journal of biological chemistry 2006 Sep 8;281(36):26633-44
The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.
Frese S, Schubert WD, Findeis AC, Marquardt T, Roske YS, Stradal TE, Heinz DW
The Journal of biological chemistry 2006 Jun 30;281(26):18236-45
The Journal of biological chemistry 2006 Jun 30;281(26):18236-45
The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network.
Bladt F, Aippersbach E, Gelkop S, Strasser GA, Nash P, Tafuri A, Gertler FB, Pawson T
Molecular and cellular biology 2003 Jul;23(13):4586-97
Molecular and cellular biology 2003 Jul;23(13):4586-97
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunoblot analysis of cell lysates.Lane 1 : U937 cell lysate. Lnae 2 : A-431 cell lysate.Lane 3 : NIH/3H3 cell lysate.Lane 4 : C6 cell lysate.