10648-1-AP
antibody from Proteintech Group
Targeting: HSD17B10
17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1
Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10648-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10648-1-AP, RRID:AB_2264270
- Product name
- ERAB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ERAB antibody (Cat. #10648-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged mice.
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.
RNase P generated tRF(Ser-GCT) promotes fat storage in adipocytes via Adrb2 signaling.
Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease.
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo.
Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.
Raising NAD(+) Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.
Leber's hereditary optic neuropathy-associated ND6 14484T > C mutation caused pleiotropic effects on the complex I, RNA homeostasis, apoptosis and mitophagy.
Effects of Dietary Fat Restriction on Endurance Training-induced Metabolic Adaptations in Rat Skeletal Muscle.
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Yao H, Su Q, Dai Q, Li L, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jan;207:115793
Subacute exposure to thallium disrupts renal energy metabolism by impairing the function of subcellular organelles in aged mice of both sexes.
Yao H, Li L, Dai Q, Li D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Nov;205:115700
Alpha-synuclein mutations mislocalize cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.
Son SM, Siddiqi FH, Lopez A, Ansari R, Tyrkalska SD, Park SJ, Kunath T, Metzakopian E, Fleming A, Rubinsztein DC
Neuron 2025 Jun 18;113(12):1908-1924.e13
Neuron 2025 Jun 18;113(12):1908-1924.e13
RNase P generated tRF(Ser-GCT) promotes fat storage in adipocytes via Adrb2 signaling.
Shen L, Lei Y, Zhao X, Wang X, Chen D, Wang K, Zhong Y, Liao T, Yang Y, Chen L, Zhao Y, Niu L, Zhou X, Gan M, Zhu L
The Journal of biological chemistry 2025 Dec;301(12):110820
The Journal of biological chemistry 2025 Dec;301(12):110820
Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease.
Wang M, Li Q, Wang S, Zuo L, Hai Y, Yuan S, Li X, Huang X, Yang C, Yao L, Cao W, Zuo G, Wang J
Phytotherapy research : PTR 2024 Sep;38(9):4519-4540
Phytotherapy research : PTR 2024 Sep;38(9):4519-4540
Testosterone regulates thymic remodeling by altering metabolic reprogramming in male rats.
Li D, Yao H, Ren Y, Shang J, Han X, Cao X, Song T, Zeng X
General and comparative endocrinology 2024 Mar 1;348:114448
General and comparative endocrinology 2024 Mar 1;348:114448
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo.
Vind AC, Wu Z, Firdaus MJ, Snieckute G, Toh GA, Jessen M, Martínez JF, Haahr P, Andersen TL, Blasius M, Koh LF, Maartensson NL, Common JEA, Gyrd-Hansen M, Zhong FL, Bekker-Jensen S
Molecular cell 2024 Dec 19;84(24):4774-4789.e9
Molecular cell 2024 Dec 19;84(24):4774-4789.e9
Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz (Wwtr1) Activation in Male LDLR-/- Mice.
Behrmann A, Zhong D, Li L, Xie S, Mead M, Sabaeifard P, Goodarzi M, Lemoff A, Kozlitina J, Towler DA
Endocrinology 2023 Dec 23;165(2)
Endocrinology 2023 Dec 23;165(2)
Raising NAD(+) Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation.
Walker MA, Chen H, Yadav A, Ritterhoff J, Villet O, McMillen T, Wang Y, Purcell H, Djukovic D, Raftery D, Isoherranen N, Tian R
Circulation 2023 Dec 19;148(25):2038-2057
Circulation 2023 Dec 19;148(25):2038-2057
Leber's hereditary optic neuropathy-associated ND6 14484T > C mutation caused pleiotropic effects on the complex I, RNA homeostasis, apoptosis and mitophagy.
Liang M, Ji Y, Zhang L, Wang X, Hu C, Zhang J, Zhu Y, Mo JQ, Guan MX
Human molecular genetics 2022 Sep 29;31(19):3299-3312
Human molecular genetics 2022 Sep 29;31(19):3299-3312
Effects of Dietary Fat Restriction on Endurance Training-induced Metabolic Adaptations in Rat Skeletal Muscle.
Karasawa T, Kondo S, Fukazawa A, Koike A, Tsutsui M, Terada S
Journal of oleo science 2021 Feb 1;70(2):253-262
Journal of oleo science 2021 Feb 1;70(2):253-262
Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A
Cell reports 2016 Aug 16;16(7):1874-90
Cell reports 2016 Aug 16;16(7):1874-90
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10648-1-AP(HSD17B10 antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 10648-1-AP( HSD17B10 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ERAB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ERAB. This antibody recognizes human,mouse,rat antigen. The ERAB antibody has been validated for the following applications: ELISA, WB, IHC analysis.