Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12745-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12745-1-AP, RRID:AB_2141563
- Product name
- MEK6 antibody
- Antibody type
- Polyclonal
- Description
- MEK6 antibody (Cat. #12745-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references WTAP-Mediated N6-Methyladenosine Modification Promotes Gastric Cancer Progression by Regulating MAP2K6 Expression.
Mycobacterium tuberculosis Rv2521 promotes ferroptosis-dependent pathogenicity by inhibiting NF-κB activation.
Targeting PRSS23 with tipranavir induces gastric cancer stem cell apoptosis and inhibits growth of gastric cancer via the MKK3/p38 MAPK-IL24 pathway.
Identification of a novel immune checkpoint-related gene signature predicts prognosis and immunotherapy in breast cancer and experiment verification.
SAMHD1, positively regulated by KLF4, suppresses the proliferation of gastric cancer cells through MAPK p38 signaling pathway.
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
L-Theanine mediates the p38MAPK signaling pathway to alleviate heat-induced oxidative stress and inflammation in mice.
The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling.
Han S, Jiang H, Wang J, Li C, Liu T, Xuan M, Tian B, Si Y, Zhao H, Zhao Y, Zhu Z, Yu W, Wang L
Journal of Cancer 2025;16(5):1420-1437
Journal of Cancer 2025;16(5):1420-1437
Mycobacterium tuberculosis Rv2521 promotes ferroptosis-dependent pathogenicity by inhibiting NF-κB activation.
Liu W, Zhu C, Zhang L, Wang Y, Zhang X, Shang X, Zhao J, Li Z, Jia H, Zhang Z, Pan L
International journal of biological macromolecules 2025 Sep;321(Pt 4):146294
International journal of biological macromolecules 2025 Sep;321(Pt 4):146294
Targeting PRSS23 with tipranavir induces gastric cancer stem cell apoptosis and inhibits growth of gastric cancer via the MKK3/p38 MAPK-IL24 pathway.
Xiong JX, Li YT, Tan XY, Chen T, Liu BH, Fu L
Acta pharmacologica Sinica 2024 Feb;45(2):405-421
Acta pharmacologica Sinica 2024 Feb;45(2):405-421
Identification of a novel immune checkpoint-related gene signature predicts prognosis and immunotherapy in breast cancer and experiment verification.
Yin K, Guo Y, Wang J, Guo S, Zhang C, Dai Y, Guo Y, Dai C
Scientific reports 2024 Dec 28;14(1):31065
Scientific reports 2024 Dec 28;14(1):31065
SAMHD1, positively regulated by KLF4, suppresses the proliferation of gastric cancer cells through MAPK p38 signaling pathway.
Chen Z, Jiang Z, Meng L, Wang Y, Lin M, Wei Z, Han W, Ying S, Xu A
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2065-2078
Cell cycle (Georgetown, Tex.) 2022 Oct;21(19):2065-2078
Skin chronological aging drives age-related bone loss via secretion of cystatin-A.
Liang W, Chen Q, Cheng S, Wei R, Li Y, Yao C, Ouyang Z, Kang D, Chen A, Liu Z, Li K, Bai X, Li Q, Huang B
Nature aging 2022 Oct;2(10):906-922
Nature aging 2022 Oct;2(10):906-922
L-Theanine mediates the p38MAPK signaling pathway to alleviate heat-induced oxidative stress and inflammation in mice.
Liu K, Liu E, Lin L, Hu Y, Yuan Y, Xiao W
Food & function 2022 Feb 21;13(4):2120-2130
Food & function 2022 Feb 21;13(4):2120-2130
The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling.
Pedrazza L, Schneider T, Bartrons R, Ventura F, Rosa JL
Scientific reports 2020 Jan 21;10(1):824
Scientific reports 2020 Jan 21;10(1):824
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 12745-1-AP(MAP2K6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The MEK6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MEK6. This antibody recognizes human,mouse,rat antigen. The MEK6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.