Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB269P-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-1 RI PE-conjugated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-1 RI in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells.
Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis.
Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways.
T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1.
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions.
Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors.
Regulating human Th17 cells via differential expression of IL-1 receptor.
Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
Saga R, Hasegawa K, Murata K, Chiba M, Nakamura T, Okumura K, Tsuruga E, Hosokawa Y
Oncology letters 2019 Mar;17(3):3555-3561
Oncology letters 2019 Mar;17(3):3555-3561
Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis.
Lee HG, Lee JU, Kim DH, Lim S, Kang I, Choi JM
Nature communications 2019 Feb 12;10(1):709
Nature communications 2019 Feb 12;10(1):709
Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways.
Mattiola I, Pesant M, Tentorio PF, Molgora M, Marcenaro E, Lugli E, Locati M, Mavilio D
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 15;195(6):2818-28
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 15;195(6):2818-28
T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
Dalmas E, Venteclef N, Caer C, Poitou C, Cremer I, Aron-Wisnewsky J, Lacroix-Desmazes S, Bayry J, Kaveri SV, Clément K, André S, Guerre-Millo M
Diabetes 2014 Jun;63(6):1966-77
Diabetes 2014 Jun;63(6):1966-77
Induction and activation of human Th17 by targeting antigens to dendritic cells via dectin-1.
Duluc D, Joo H, Ni L, Yin W, Upchurch K, Li D, Xue Y, Klucar P, Zurawski S, Zurawski G, Oh S
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5776-88
Journal of immunology (Baltimore, Md. : 1950) 2014 Jun 15;192(12):5776-88
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions.
Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, Li B, Olsen NJ, Zheng SG
Proceedings of the National Academy of Sciences of the United States of America 2014 Aug 19;111(33):E3432-40
Proceedings of the National Academy of Sciences of the United States of America 2014 Aug 19;111(33):E3432-40
Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors.
Mercer F, Khaitan A, Kozhaya L, Aberg JA, Unutmaz D
Journal of immunology (Baltimore, Md. : 1950) 2014 Aug 1;193(3):1047-54
Journal of immunology (Baltimore, Md. : 1950) 2014 Aug 1;193(3):1047-54
Regulating human Th17 cells via differential expression of IL-1 receptor.
Lee WW, Kang SW, Choi J, Lee SH, Shah K, Eynon EE, Flavell RA, Kang I
Blood 2010 Jan 21;115(3):530-40
Blood 2010 Jan 21;115(3):530-40
Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
Kalliolias GD, Gordon RA, Ivashkiv LB
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):7047-56
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 1;185(11):7047-56
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IL-1 RI in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Goat Anti-Human IL-1 RI PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB269P, filled histogram) or control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.