Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AGTO-L026P - Provider product page
- Provider
- Creative Biolabs
- Product name
- anti-IL1R1 immunotoxin TP3 (IgG)-PAP
- Antibody type
- Monoclonal
- Description
- This immunotoxin was achieved by conjugating/fusing the Anti-IL1R1 monoclonal antibody to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to osteosarcoma cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of osteosarcoma.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- TP3
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