AGTO-L026P

antibody from Creative Biolabs

Targeting: IL1R1 CD121A, D2S1473, IL1R, IL1RA

Functional assay (Recommended by provider)

Antibody Data

Product number

AGTO-L026P

Provider

Creative Biolabs

Product name

anti-IL1R1 immunotoxin TP3 (IgG)-PAP

Antibody type

Monoclonal

Description

This immunotoxin was achieved by conjugating/fusing the Anti-IL1R1 monoclonal antibody to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to osteosarcoma cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of osteosarcoma.

Reactivity

Human

Host

Mouse

Antibody clone number

TP3