PIR

This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Description

pirin

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

X:p22.2 (15384799 - 15493564)

Ensembl ID

ENSG00000087842  (ver. 84.38)

Orthologs

Mouse Pir: ENSMUSG00000031379

UniProt

O00625

neXtProt

NX_O00625

Human splice variants
Mouse splice variants