10566-1-AP

antibody from Proteintech Group

Targeting: GYS1 GSY, GYS

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

10566-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10566-1-AP, RRID:AB_2116401

Product name

GYS1 antibody

Antibody type

Polyclonal

Description

KD/KO validated GYS1 antibody (Cat. #10566-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Si-Ni-San promotes liver regeneration by maintaining hepatic oxidative equilibrium and glucose/lipid metabolism homeostasis.

Yang X, Zhang J, Li Y, Hu H, Li X, Ma T, Zhang B
Journal of ethnopharmacology 2024 May 23;326:117918

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Radix Astragali decoction improves liver regeneration by upregulating hepatic expression of aquaporin-9.

Li Y, Yang X, Bao T, Sun X, Li X, Zhu H, Zhang B, Ma T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155166

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Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma.

Zhang Y, Sun J, Li M, Hou L, Wang Z, Dong H, Xu W, Jiang R, Geng Y, Guan C, Zhu Z, Wang H, Gong Q, Zhang G
Heliyon 2024 Jan 15;10(1):e23502

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PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.

Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909

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Construction and experimental validation of a signature for predicting prognosis and immune infiltration analysis of glioma based on disulfidptosis-related lncRNAs.

Guo Y, Jiang Z, Chen Q, Xie D, Zhou Y, Yin W, Wang Z, Wang B, Ren C, Jiang X
Frontiers in immunology 2023;14:1291385

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Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.

Koleini N, Meddeb M, Keykhaei M, Kwon S, Zhao L, Hahn V, Sharma K, Pearce EL, Kass DA
medRxiv : the preprint server for health sciences 2023 Oct 2;

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Douchi Peptides VY and SFLLR Improve Glucose Homeostasis and Gut Dysbacteriosis in High-Fat Diet-Induced Insulin Resistant Mice.

Yu S, Wang W, Wang H, Bu T, Liu L, Zhao R, Li S, Liu D, Wu J
Molecular nutrition & food research 2023 May;67(10):e2200681

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Identification of novel immune subtypes and potential hub genes of patients with psoriasis.

Li Y, Li L, Tian Y, Luo J, Huang J, Zhang L, Zhang J, Li X, Hu L
Journal of translational medicine 2023 Mar 8;21(1):182

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Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight.

Doi M, Nakama N, Sumi T, Usui N, Shimada S
Frontiers in endocrinology 2022;13:1023984

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Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or systemic lipolysis in rat.

Liu Z, Zhang L, Qian C, Zhou Y, Yu Q, Yuan J, Lv Y, Zhang L, Chang X, Li Y, Liu Y
Metabolism: clinical and experimental 2022 Nov;136:155310

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Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.

Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690

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Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

Gu Z, Zhang H, Guo X, Cao Y
The Journal of investigative dermatology 2020 Aug;140(8):1513-1523.e5

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Retinol binding protein 4 mediates MEHP-induced glucometabolic abnormalities in HepG2 cells.

Wang F, Chang C, Li R, Zhang Z, Jiang H, Zeng N, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2019 Aug 1;424:152236

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ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes.

Dong K, Ni H, Wu M, Tang Z, Halim M, Shi D
Biochemical and biophysical research communications 2016 Aug 5;476(4):204-211

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Inducible metabolic adaptation promotes mesenchymal stem cell therapy for ischemia: a hypoxia-induced and glycogen-based energy prestorage strategy.

Zhu H, Sun A, Zou Y, Ge J
Arteriosclerosis, thrombosis, and vascular biology 2014 Apr;34(4):870-6

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A single centrifugation method for isolating fat droplets from cells and tissues.

Harris LLS, Shew TM, Skinner JR, Wolins NE
Journal of lipid research 2012 May;53(5):1021-1025

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Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.

Hall AM, Brunt EM, Chen Z, Viswakarma N, Reddy JK, Wolins NE, Finck BN
Journal of lipid research 2010 Mar;51(3):554-63

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

K-562 cells were subjected to SDS PAGE followed by western blot with 10566-1-AP(GYS1 antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using GYS1 antibody 10566-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human prostate cancer using 10566-1-AP(GYS1 antibody) at dilution of 1:50 (under 25x lens)

Sample type

tissue