Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX107921 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX107921, RRID:AB_1950865
- Product name
- ASK1 antibody [C2C3-2], C-term
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.
A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing.
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.
Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.
Deletion of apoptosis signal-regulating kinase-1 prevents ventilator-induced lung injury in mice.
Zhang P, Wang PX, Zhao LP, Zhang X, Ji YX, Zhang XJ, Fang C, Lu YX, Yang X, Gao MM, Zhang Y, Tian S, Zhu XY, Gong J, Ma XL, Li F, Wang Z, Huang Z, She ZG, Li H
Nature medicine 2018 Jan;24(1):84-94
Nature medicine 2018 Jan;24(1):84-94
A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing.
Ghosh MC, Makena PS, Kennedy J, Teng B, Luellen C, Sinclair SE, Waters CM
Scientific reports 2017 May 19;7(1):2155
Scientific reports 2017 May 19;7(1):2155
The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling.
Ji YX, Zhang P, Zhang XJ, Zhao YC, Deng KQ, Jiang X, Wang PX, Huang Z, Li H
Nature communications 2016 Jun 1;7:11267
Nature communications 2016 Jun 1;7:11267
Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.
Chiu SC, Chen SP, Huang SY, Wang MJ, Lin SZ, Harn HJ, Pang CY
PloS one 2012;7(3):e33742
PloS one 2012;7(3):e33742
Deletion of apoptosis signal-regulating kinase-1 prevents ventilator-induced lung injury in mice.
Makena PS, Gorantla VK, Ghosh MC, Bezawada L, Kandasamy K, Balazs L, Luellen CL, Thompson KE, Parthasarathi K, Ichijo H, Waters CM, Sinclair SE
American journal of respiratory cell and molecular biology 2012 Apr;46(4):461-9
American journal of respiratory cell and molecular biology 2012 Apr;46(4):461-9
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- ASK1 antibody [C2C3-2], C-term detects MAP3K5 protein by Western blot analysis.A. 50 ?g mouse lung lysate/extract 5 % SDS-PAGEASK1 antibody [C2C3-2], C-term (GTX107921) dilution: 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample(30 ug whole cell lysate)A:HeLa S3(GTX14654)5% SDS PAGEGTX107921 diluted at 1:1000
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ASK1(GTX107921) antibody at 1:500 dilution.