PAB16964

antibody from Abnova Corporation

Targeting: MAP3K5 ASK1, MAPKKK5, MEKK5

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB16964

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB16964, RRID:AB_10615457

Product name

MAP3K5 (phospho S966) polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAP3K5.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.

Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H
EMBO reports 2001 Mar;2(3):222-8

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Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1.

Matsuzawa A, Ichijo H
Journal of biochemistry 2001 Jul;130(1):1-8

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways.

Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y
Science (New York, N.Y.) 1997 Jan 3;275(5296):90-4

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue using MAP3K5 (phospho Ser966) polyclonal antibody (Cat # PAB16964).

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)