Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362195 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer966) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer966 (S-I-S (p) -L-P) derived from Human ASK1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- pSer966
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor.
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation.
Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.
Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins.
Zhang W, Zheng S, Storz P, Min W
The Journal of biological chemistry 2005 May 13;280(19):19036-44
The Journal of biological chemistry 2005 May 13;280(19):19036-44
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation.
Goldman EH, Chen L, Fu H
The Journal of biological chemistry 2004 Mar 12;279(11):10442-9
The Journal of biological chemistry 2004 Mar 12;279(11):10442-9
Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.
Fujii K, Goldman EH, Park HR, Zhang L, Chen J, Fu H
Oncogene 2004 Jun 24;23(29):5099-104
Oncogene 2004 Jun 24;23(29):5099-104
Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins.
Zhang L, Chen J, Fu H
Proceedings of the National Academy of Sciences of the United States of America 1999 Jul 20;96(15):8511-5
Proceedings of the National Academy of Sciences of the United States of America 1999 Jul 20;96(15):8511-5
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