67072-1-Ig

antibody from Proteintech Group

Targeting: MAP3K5 ASK1, MAPKKK5, MEKK5

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67072-1-Ig

Provider

Proteintech Group

Product name

ASK1 antibody

Antibody type

Monoclonal

Description

ASK1 antibody (Cat. #67072-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1C3A10

Vial size

20ul, 150ul

References

Submitted references

Identification and validation of the VEGF/p38MAPK/HSP27 pro-tumor inflammatory pathway: screening of active components from Patrinia villosa and evaluation of their drug-likeness.

Li X, Ju Y, Yang X, Li T, Wang S, Bao Y, Meng X
Frontiers in immunology 2025;16:1631031

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A positive feedback loop of OTUD1 and c-Jun driven by leptin expedites stemness maintenance in ovarian cancer.

Wang J, Yang F, Chen Y, Xing Y, Huang J, Cao J, Xiong J, Liu Y, Zhao Q, Luo M, Xiong J, Fan G, Lyu Q, Li F, Zhang W
Oncogene 2025 Jun;44(22):1731-1745

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Mcl-1 downregulation enhances BCG treatment efficacy in bladder cancer by promoting macrophage polarization.

Tan C, Li C, Ge R, Zhang W, Wu Z, Wang S, Cui H, Wang X, Zhang L
Cancer cell international 2025 Feb 15;25(1):48

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Unlocking the potential of garlic by-product protein: Ultrasound-induced structural modification and fabrication of an ACE inhibitory peptide targeting endothelial dysfunction.

Xiang L, Qiu Z, Zheng Z, Chen H, Qiao Y
Ultrasonics sonochemistry 2025 Dec;123:107642

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ABT‑737 increases cisplatin sensitivity through the ROS‑ASK1‑JNK MAPK signaling axis in human ovarian cancer cisplatin‑resistant A2780/DDP cells.

Li X, Guo Y, Xing Z, Gong T, Yang L, Yang T, Chang B, Wang X, Yu B, Guo R
Oncology reports 2024 Sep;52(3)

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Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer.

Chen Y, Qiang Y, Fan J, Zheng Q, Yan L, Fan G, Song X, Zhang N, Lv Q, Xiong J, Wang J, Cao J, Liu Y, Xiong J, Zhang W, Li F
Nature communications 2024 Feb 13;15(1):1321

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Cardiac tumour necrosis factor receptor-associated factor 7 mediates the ubiquitination of apoptosis signal-regulating kinase 1 and aggravates cardiac hypertrophy.

Che Y, Liu YT, Wang ZP, Feng YZ, Xia HX, Yuan Y, Zhou H, Qiu HL, Hu ML, Wang SS, Tang QZ
Cardiovascular research 2024 Dec 14;120(16):2031-2046

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Exploring the mechanism of Xingpi Capsule in diarrhea predominant-irritable bowel syndrome treatment based on multiomics technology.

Qian W, Li W, Chen X, Cui L, Liu X, Yao J, Wang X, Liu Y, Li C, Wang Y, Wang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154653

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ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.

Duan J, Yuan W, Jiang J, Wang J, Yan X, Liu F, Liu A
Molecular medicine reports 2023 Feb;27(2)

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Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex.

Lei N, Song H, Zeng L, Ji S, Meng X, Zhu X, Li X, Feng Q, Liu J, Mu J
Molecules (Basel, Switzerland) 2023 Apr 3;28(7)

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Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.

Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154

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Erratum: Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization.

Fan M, Xiao H, Song D, Zhu L, Zhang J, Zhang X, Wang J, Dai H, Wang C
Frontiers in pharmacology 2022;13:1108989

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Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.

Jiang XL, Tai H, Kuang JS, Zhang JY, Cui SC, Lu YX, Qi SB, Zhang SY, Li SM, Chen JP, Meng XS
Aging 2022 Oct 27;14(20):8321-8345

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Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma.

Li X, Chen Q, Liu J, Lai S, Zhang M, Zhen T, Hu H, Gao X, Wong AST, Zeng JZ
Cells 2022 Dec 1;11(23)