ABIN965599

antibody from antibodies-online

Targeting: MAP3K5 ASK1, MAPKKK5, MEKK5

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965599

Provider

antibodies-online

Product name

anti-Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (pSer966) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human ASK1 around the phosphorylation site of serine 966 (S-I-SP-L-P).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pSer966

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor.

Zhang W, Zheng S, Storz P, Min W
The Journal of biological chemistry 2005 May 13;280(19):19036-44

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Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation.

Goldman EH, Chen L, Fu H
The Journal of biological chemistry 2004 Mar 12;279(11):10442-9

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Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.

Fujii K, Goldman EH, Park HR, Zhang L, Chen J, Fu H
Oncogene 2004 Jun 24;23(29):5099-104