Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15100-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15100-1-AP, RRID:AB_2202885
- Product name
- TGM2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TGM2 antibody (Cat. #15100-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pirfenidone alleviates fibrosis by acting on tumour-stroma interplay in pancreatic cancer.
mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms.
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells.
Transglutaminases are oncogenic biomarkers in human cancers and therapeutic targeting of TGM2 blocks chemoresistance and macrophage infiltration in pancreatic cancer.
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Damaged collagen detected by collagen hybridizing peptide as efficient diagnosis marker for early hepatic fibrosis.
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
Peroxiredoxins and Hypoxia-Inducible Factor-1α in Duodenal Tissue: Emerging Factors in the Pathophysiology of Pediatric Celiac Disease Patients.
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages.
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma.
Elevated tissue transglutaminase levels in aqueous humor of congenital cataractous eyes with long axial length.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
TGM2 positively regulates myoblast differentiation via enhancing the mTOR signaling.
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF-κB Signaling.
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.
Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer.
TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts.
Immune subtyping for pancreatic cancer with implication in clinical outcomes and improving immunotherapy.
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Lei Y, Xu J, Xiao M, Wu D, Xu H, Yang J, Mao X, Pan H, Yu X, Shi S
British journal of cancer 2024 May;130(9):1505-1516
British journal of cancer 2024 May;130(9):1505-1516
mTOR Regulates Mineralocorticoid Receptor Transcriptional Activity by ULK1-Dependent and -Independent Mechanisms.
Ali Y, Gomez-Sanchez CE, Plonczynski M, Naray-Fejes-Toth A, Fejes-Toth G, Gomez-Sanchez EP
Endocrinology 2024 Feb 20;165(4)
Endocrinology 2024 Feb 20;165(4)
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells.
González-Moro I, Rojas-Márquez H, Sebastian-delaCruz M, Mentxaka-Salgado J, Olazagoitia-Garmendia A, Mendoza LM, Lluch A, Fantuzzi F, Lambert C, Ares Blanco J, Marselli L, Marchetti P, Cnop M, Delgado E, Fernández-Real JM, Ortega FJ, Castellanos-Rubio A, Santin I
Frontiers in endocrinology 2023;14:1101934
Frontiers in endocrinology 2023;14:1101934
Transglutaminases are oncogenic biomarkers in human cancers and therapeutic targeting of TGM2 blocks chemoresistance and macrophage infiltration in pancreatic cancer.
Zhang S, Yao HF, Li H, Su T, Jiang SH, Wang H, Zhang ZG, Dong FY, Yang Q, Yang XM
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1473-1492
Cellular oncology (Dordrecht, Netherlands) 2023 Oct;46(5):1473-1492
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
Li X, Ma Y, Wu J, Ni M, Chen A, Zhou Y, Dai W, Chen Z, Jiang R, Ling Y, Yao Q, Chen W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857
Autophagy 2023 Mar;19(3):839-857
Damaged collagen detected by collagen hybridizing peptide as efficient diagnosis marker for early hepatic fibrosis.
Tao P, Liu J, Li Y, Zhang T, Wang F, Chang L, Li C, Ge X, Zuo T, Lu S, Ruan Y, Yang Z, Xu P
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194928
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194928
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
Li Y, Sun H, Liu X, Hu Z, Jiang H, Guo H, Long X
International immunopharmacology 2023 Jan;114:109486
International immunopharmacology 2023 Jan;114:109486
Peroxiredoxins and Hypoxia-Inducible Factor-1α in Duodenal Tissue: Emerging Factors in the Pathophysiology of Pediatric Celiac Disease Patients.
Köse FA, Pabuccuoglu A, Karakoyun M, Aydogdu S
Current issues in molecular biology 2023 Feb 20;45(2):1779-1793
Current issues in molecular biology 2023 Feb 20;45(2):1779-1793
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease.
Gruper Y, Wolff ASB, Glanz L, Spoutil F, Marthinussen MC, Osickova A, Herzig Y, Goldfarb Y, Aranaz-Novaliches G, Dobeš J, Kadouri N, Ben-Nun O, Binyamin A, Lavi B, Givony T, Khalaila R, Gome T, Wald T, Mrazkova B, Sochen C, Besnard M, Ben-Dor S, Feldmesser E, Orlova EM, Hegedűs C, Lampé I, Papp T, Felszeghy S, Sedlacek R, Davidovich E, Tal N, Shouval DS, Shamir R, Guillonneau C, Szondy Z, Lundin KEA, Osicka R, Prochazka J, Husebye ES, Abramson J
Nature 2023 Dec;624(7992):653-662
Nature 2023 Dec;624(7992):653-662
4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages.
Lin CC, Law BF, Hettick JM
Xenobiotica; the fate of foreign compounds in biological systems 2023 Dec;53(12):653-669
Xenobiotica; the fate of foreign compounds in biological systems 2023 Dec;53(12):653-669
An immunogenic cell death-related signature predicts prognosis and immunotherapy response in stomach adenocarcinoma.
Liu Z, Sun L, Peng X, Liu S, Zhu Z, Huang C
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1564-1583
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1564-1583
Elevated tissue transglutaminase levels in aqueous humor of congenital cataractous eyes with long axial length.
Yang T, Zhou X, Li H, Fan F, Yang J, Lin X, Liu X, Luo Y
Heliyon 2023 Aug;9(8):e18709
Heliyon 2023 Aug;9(8):e18709
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
TGM2 positively regulates myoblast differentiation via enhancing the mTOR signaling.
Wang D, Zhao D, Li Y, Dai T, Liu F, Yan C
Biochimica et biophysica acta. Molecular cell research 2022 Mar;1869(3):119173
Biochimica et biophysica acta. Molecular cell research 2022 Mar;1869(3):119173
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Sokouti H, Mohajeri D, Nourazar MA
Physiological research 2022 Aug 31;71(4):551-560
Physiological research 2022 Aug 31;71(4):551-560
Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF-κB Signaling.
Hou Y, Xiao X, Yu W, Qi S
Journal of immunology research 2021;2021:4754454
Journal of immunology research 2021;2021:4754454
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.
Ye D, Xu H, Xia H, Zhang C, Tang Q, Bi F
Journal of experimental & clinical cancer research : CR 2021 May 18;40(1):173
Journal of experimental & clinical cancer research : CR 2021 May 18;40(1):173
Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer.
Mitachi K, Ariake K, Shima H, Sato S, Miura T, Maeda S, Ishida M, Mizuma M, Ohtsuka H, Kamei T, Igarashi K, Unno M
Scientific reports 2021 Mar 22;11(1):6541
Scientific reports 2021 Mar 22;11(1):6541
TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts.
Semkova ME, Hsuan JJ
International journal of molecular sciences 2021 Jan 20;22(3)
International journal of molecular sciences 2021 Jan 20;22(3)
Immune subtyping for pancreatic cancer with implication in clinical outcomes and improving immunotherapy.
Liu J, Liu Q, Zhang X, Cui M, Li T, Zhang Y, Liao Q
Cancer cell international 2021 Feb 26;21(1):137
Cancer cell international 2021 Feb 26;21(1):137
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Chen Y, Wang Y, Lin W, Sheng R, Wu Y, Xu R, Zhou C, Yuan Q
Cell proliferation 2020 Jun;53(6):e12831
Cell proliferation 2020 Jun;53(6):e12831
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.
Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, Yang B, Qin G, Kong R, Chen R, Zhang N
Nature communications 2020 Jun 22;11(1):3162
Nature communications 2020 Jun 22;11(1):3162
Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway.
Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, Zhao Y, Ommati MM, Manthari RK, Wang J
Food & function 2020 Jan 29;11(1):1155-1164
Food & function 2020 Jan 29;11(1):1155-1164
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TGM2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TGM2. This antibody recognizes human, mouse, rat antigen. The TGM2 antibody has been validated for the following applications: ELISA, WB analysis.