orb460116

antibody from Biorbyt
Targeting: TGM2 TGC
Provider product page for orb460116
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb460116 - Provider product page
Provider
Biorbyt
Product name
Transglutaminase 2 antibody (Biotin)
Antibody type
Polyclonal
Description
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Biotin
Isotype
IgG
Vial size
100 ul
Concentration
1mg/ml
Storage
Shipped at 4°C. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
TGM2 protein structure - orb460116 shown in red.