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- Antigen structure
- References [238]
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- Product number
- 13050-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13050-1-AP, RRID:AB_2079881
- Product name
- Claudin 1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Claudin 1 antibody (Cat. #13050-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, canine and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Social isolation induces intestinal barrier disorder and imbalances gut microbiota in mice.
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
Exposure to hexa(fl)uoropropylene oxide trimer acid (HFPO-TA) impairs 5-HT metabolism by impacting the brain-gut axis in mice.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Construction of a dual-component hydrogel matrix for 3D biomimetic skin based on photo-crosslinked chondroitin sulfate/collagen.
Baizhu shaoyao decoction restores the intestinal barrier and brain-gut axis balance to alleviate diarrhea-predominant irritable bowel syndrome via FoxO1/FoxO3a.
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Huanglian Ganjiang decoction alleviates ulcerative colitis by restoring gut barrier via APOC1-JNK/P38 MAPK signal pathway based on proteomic analysis.
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Neuroprotective Effect of a Multistrain Probiotic Mixture in SOD1(G93A) Mice by Reducing SOD1 Aggregation and Targeting the Microbiota-Gut-Brain Axis.
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder.
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Critical contributions of protein cargos to the functions of macrophage-derived extracellular vesicles.
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury.
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
A High-Fat Diet Increases the Characteristics of Gut Microbial Composition and the Intestinal Damage Associated with Non-Alcoholic Fatty Liver Disease.
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Rice bran oil supplementation protects swine weanlings against diarrhea and lipopolysaccharide challenge.
High concentrate diet induced inflammatory response and tight junction disruption in the mammary gland of dairy cows.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Open hepatic artery flow with portal vein clamping protects against bile duct injury compared to pringles maneuver.
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Disordered gut microbiota promotes atrial fibrillation by aggravated conduction disturbance and unbalanced linoleic acid/SIRT1 signaling.
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Sodium butyrate protects against rotavirus-induced intestinal epithelial barrier damage by activating AMPK-Nrf2 signaling pathway in IPEC-J2 cells.
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
A high-concentrate diet induces colonic inflammation and barrier damage in Hu sheep.
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Roseburia intestinalis relieves intrahepatic cholestasis of pregnancy through bile acid/FXR-FGF15 in rats.
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Ginkgo biloba Extract Preventively Intervenes in Citrobacter Rodentium-Induced Colitis in Mice.
The Uterine Melatonergic Systems of AANAT and Melatonin Membrane Receptor 2 (MT2) Are Essential for Endometrial Receptivity and Early Implantation in Mice.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
3,4-Methylenedioxy-β-Nitrostyrene Alleviates Dextran Sulfate Sodium-Induced Mouse Colitis by Inhibiting the NLRP3 Inflammasome.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Porphyromonas gingivalis secretion leads to dysplasia of normal esophageal epithelial cells via the Sonic hedgehog pathway.
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer.
Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Spinal anesthesia alleviates dextran sodium sulfate-induced colitis by modulating the gut microbiota.
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Polysaccharides from Lachnum sp. Inhibited colitis-associated colon tumorigenesis in mice by modulating fecal microbiota and metabolites.
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
The miR-199a-5p/PD-L1 axis regulates cell proliferation, migration and invasion in follicular thyroid carcinoma.
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier.
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis.
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Highly Pathogenic PRRSV-Infected Alveolar Macrophages Impair the Function of Pulmonary Microvascular Endothelial Cells.
Dietary ellagic acid supplementation attenuates intestinal damage and oxidative stress by regulating gut microbiota in weanling piglets.
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Deoxynivalenol damages the intestinal barrier and biota of the broiler chickens.
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets.
Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Melatonin as Immune Potentiator for Enhancing Subunit Vaccine Efficacy against Bovine Viral Diarrhea Virus.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 Mixture Prevents Chronic Alcoholic Liver Injury in Mice by Protecting the Intestinal Barrier and Regulating Gut Microbiota and Liver-Related Pathways.
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Intraperitoneal supplementation of iron alleviates dextran sodium sulfate-induced colitis by enhancing intestinal barrier function.
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Immunization with recombinant E(rns)-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
Dietary glycyl-glutamine supplementation ameliorates intestinal integrity, inflammatory response, and oxidative status in association with the gut microbiota in LPS-challenged piglets.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth.
Caveolin-1 protects against DSS-induced colitis through inhibiting intestinal nitrosative stress and mucosal barrier damage in mice.
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Targeting claudin-4 enhances chemosensitivity in breast cancer.
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Exposure to dibutyl phthalate impairs lipid metabolism and causes inflammation via disturbing microbiota-related gut-liver axis.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier.
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
The chromatin remodeling protein BRM regulates the transcription of tight junction proteins: Implication in breast cancer metastasis.
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers.
All‑trans retinoic acid alters the expression of the tight junction proteins Claudin‑1 and ‑4 and epidermal barrier function‑associated genes in the epidermis.
The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway.
Natural killer T cell ligand alpha-galactosylceramide protects against gut ischemia reperfusion-induced organ injury in mice.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin.
Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.
KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling.
(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Cheng R, Wang J, Wu Q, Peng P, Liao G, Luo X, Liang Z, Huang J, Qin M
International journal of general medicine 2024;17:1937-1948
International journal of general medicine 2024;17:1937-1948
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
Zhang Y, Qiao Y, Li Z, Liu D, Jin Q, Guo J, Li X, Chen L, Liu L, Peng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Deng H, Ye T, Deng Y, Cui Y, Guo H, Deng J
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276
Gene 2024 May 20;907:148276
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Yang MJ, Zhang YN, Qiao Z, Xu RY, Chen SM, Hu P, Yu HL, Pan Y, Cao J
Journal of ethnopharmacology 2024 May 10;325:117807
Journal of ethnopharmacology 2024 May 10;325:117807
Hippocampal and gut AMPK activation attenuates enterocolitis-like symptoms and co-occurring depressive-like behavior in ulcerative colitis model mice: Involvement of brain-gut autophagy.
Takahashi K, Kurokawa K, Hong L, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M
Experimental neurology 2024 Mar;373:114671
Experimental neurology 2024 Mar;373:114671
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
Wang J, Wang S, Okyere SK, Wen J, Wang X, Huang R, Tang Z, Cao S, Deng J, Ren Z, Hu Y
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
Wu X, Zhang Y, Ji M, Yang W, Deng T, Hou G, Shi L, Xun W
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Huang Z, Zhong H, Li T, Wang Z, Chen X, Zou T, You J, Chen J
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Social isolation induces intestinal barrier disorder and imbalances gut microbiota in mice.
Wang Y, Ullah H, Deng T, Ren X, Zhao Z, Xin Y, Qiu J
Neuroscience letters 2024 Mar 15;826:137714
Neuroscience letters 2024 Mar 15;826:137714
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Li B, Jiang XF, Dong YJ, Zhang YP, He XL, Zhou CL, Ding YY, Wang N, Wang YB, Cheng WQ, Jiang NH, Su J, Lv GY, Chen SH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Zhang S, Li Y, Chen G, Wang X, Wu B
Journal of ethnopharmacology 2024 Jun 28;328:118131
Journal of ethnopharmacology 2024 Jun 28;328:118131
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
Shan Q, Ma W, Li B, Li Q, Wang X, Li Y, Wang J, Zhu Y, Liu N
International journal of molecular sciences 2024 Jun 18;25(12)
International journal of molecular sciences 2024 Jun 18;25(12)
Exposure to hexa(fl)uoropropylene oxide trimer acid (HFPO-TA) impairs 5-HT metabolism by impacting the brain-gut axis in mice.
Xie X, Sun L, Xu H, Zhang M, Zhou J, Du S, Hu Q, Li Z
Chemosphere 2024 Jul;359:142035
Chemosphere 2024 Jul;359:142035
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Gao L, Zhang AP, Fu L, Li QW, Qin XM, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155594
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Wang X, Xie X, Li Y, Xie X, Huang S, Pan S, Zou Y, Pan Z, Wang Q, Chen J, Zhou L, Luo X
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Construction of a dual-component hydrogel matrix for 3D biomimetic skin based on photo-crosslinked chondroitin sulfate/collagen.
He S, Li H, Chi B, Zhang X, Wang Y, Wu J, Huang Q
International journal of biological macromolecules 2024 Jan;254(Pt 3):127940
International journal of biological macromolecules 2024 Jan;254(Pt 3):127940
Baizhu shaoyao decoction restores the intestinal barrier and brain-gut axis balance to alleviate diarrhea-predominant irritable bowel syndrome via FoxO1/FoxO3a.
Wei Y, Fan Y, Huang S, Lv J, Zhang Y, Hao Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155163
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155163
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Liu L, Gong X, Zhang X, Zhang D, Tang Y, Liu J, Li Y, Pan D
Poultry science 2024 Jan;103(1):103242
Poultry science 2024 Jan;103(1):103242
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Jiang Y, Wang J, Li H, Li C, Zhang D
International immunopharmacology 2024 Jan 5;126:111301
International immunopharmacology 2024 Jan 5;126:111301
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Wang Y, Xie Z, Wu X, Du L, Chong Z, Liu R, Han J
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Wang X, Wang J, Okyere SK, Huang R, Shao C, Yousif M, Deng J, Hu Y
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
Huanglian Ganjiang decoction alleviates ulcerative colitis by restoring gut barrier via APOC1-JNK/P38 MAPK signal pathway based on proteomic analysis.
He YX, Li YY, Wu YQ, Ren LZ, Wang Y, Wang YM, Yu Y
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116994
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116994
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Jin T, Zhan X, Pang L, Peng B, Zhang X, Zhu W, Yang B, Xia X
Food microbiology 2024 Feb;117:104393
Food microbiology 2024 Feb;117:104393
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Yang YH, Chen C, Zheng Y, Wu ZJ, Zhou MQ, Liu XY, Miyashita K, Duan DL, Du L
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Neuroprotective Effect of a Multistrain Probiotic Mixture in SOD1(G93A) Mice by Reducing SOD1 Aggregation and Targeting the Microbiota-Gut-Brain Axis.
Xin Z, Xin C, Huo J, Liu Q, Dong H, Li R, Liu Y
Molecular neurobiology 2024 Dec;61(12):10051-10071
Molecular neurobiology 2024 Dec;61(12):10051-10071
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Ren YR, Cui WT, Jiang KL, He KQ, Lu YM, Chen Y, Pan WJ
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder.
Chen C, Xu JL, Gu ZC, Zhou SS, Wei GL, Gu JL, Ma HL, Feng YQ, Song ZW, Yan ZP, Deng S, Ding R, Li SL, Huo JG
Chinese medicine 2024 Apr 7;19(1):58
Chinese medicine 2024 Apr 7;19(1):58
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Xia S, Yan C, Gu J, Yuan Y, Zou H, Liu Z, Bian J
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Wang F, Qian F, Zhang Q, Zhao J, Cen J, Zhang J, Zhou J, Luo M, Jia C, Rong X, Chu M
Frontiers in immunology 2023;14:1124118
Frontiers in immunology 2023;14:1124118
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Sun E, Meng X, Kang Z, Gu H, Li M, Tan X, Feng L, Jia X
Frontiers in pharmacology 2023;14:1123819
Frontiers in pharmacology 2023;14:1123819
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Ding S, Cheng Y, Azad MAK, Dong H, He J, Huang P, Kong X
Frontiers in immunology 2023;14:1104837
Frontiers in immunology 2023;14:1104837
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228
Frontiers in pharmacology 2023;14:1098228
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Ullah H, Deng T, Ali M, Farooqui NA, Alsholi DM, Siddiqui NZ, Rehman AU, Ali S, Ilyas M, Wang L, Xin Y
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Critical contributions of protein cargos to the functions of macrophage-derived extracellular vesicles.
Liu B, Nguyen PL, Yu H, Li X, Wang H, Price J, Niu M, Guda C, Cheng X, Sun X, Moreau R, Ramer-Tait A, Naldrett MJ, Alvarez S, Yu J
Journal of nanobiotechnology 2023 Sep 28;21(1):352
Journal of nanobiotechnology 2023 Sep 28;21(1):352
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
Tang X, Huang J, Jiang Y, Qiu J, Li T, Li W, Chen Z, Huang Z, Yu X, Yang T, Ji X, Tan R, Lv L, Yang Z, Chen H
Journal of translational medicine 2023 Sep 27;21(1):670
Journal of translational medicine 2023 Sep 27;21(1):670
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Li X, Gou F, Xiao K, Zhu J, Lin Q, Yu M, Hong Q, Hu C
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury.
Huang B, Gui M, An H, Shen J, Ye F, Ni Z, Zhan H, Che L, Lai Z, Zeng J, Peng J, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115387
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115387
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Li F, Zhang Z, Bai Y, Che Q, Cao H, Guo J, Su Z
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Mao A, Zhao W, Zhu Y, Kong F, Chen D, Si H, Xu C
Microorganisms 2023 Oct 24;11(11)
Microorganisms 2023 Oct 24;11(11)
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Wu S, Wu Z, Chen Y
Nutrients 2023 Oct 16;15(20)
Nutrients 2023 Oct 16;15(20)
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
L-arabinose Attenuates LPS-Induced Intestinal Inflammation and Injury through Reduced M1 Macrophage Polarization.
Kang L, Pang J, Zhang X, Liu Y, Wu Y, Wang J, Han D
The Journal of nutrition 2023 Nov;153(11):3327-3340
The Journal of nutrition 2023 Nov;153(11):3327-3340
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Liu H, Xi Q, Tan S, Qu Y, Meng Q, Zhang Y, Cheng Y, Wu G
International immunopharmacology 2023 Nov;124(Pt B):111001
International immunopharmacology 2023 Nov;124(Pt B):111001
A High-Fat Diet Increases the Characteristics of Gut Microbial Composition and the Intestinal Damage Associated with Non-Alcoholic Fatty Liver Disease.
Zhu X, Cai J, Wang Y, Liu X, Chen X, Wang H, Wu Z, Bao W, Fan H, Wu S
International journal of molecular sciences 2023 Nov 24;24(23)
International journal of molecular sciences 2023 Nov 24;24(23)
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Ma Y, Shan K, Huang Z, Zhao D, Zhang M, Ke W, Li C
Molecular nutrition & food research 2023 May;67(10):e2200649
Molecular nutrition & food research 2023 May;67(10):e2200649
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
Suter C, Colakovic M, Bieri J, Gultom M, Dijkman R, Ros C
PLoS pathogens 2023 May;19(5):e1011402
PLoS pathogens 2023 May;19(5):e1011402
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Liu S, Huang Q, Huang Q, Wang Y, Li S, Wang J, Wu Q
Scientific reports 2023 May 4;13(1):7276
Scientific reports 2023 May 4;13(1):7276
Rice bran oil supplementation protects swine weanlings against diarrhea and lipopolysaccharide challenge.
Huang J, Qin W, Xu B, Sun H, Jing F, Xu Y, Zhao J, Chen Y, Ma L, Yan X
Journal of Zhejiang University. Science. B 2023 May 15;24(5):430-441
Journal of Zhejiang University. Science. B 2023 May 15;24(5):430-441
High concentrate diet induced inflammatory response and tight junction disruption in the mammary gland of dairy cows.
Wang Y, Wang L, Meng M, Huo R, Ma N, Chang G, Shen X
Microbial pathogenesis 2023 Mar;176:105996
Microbial pathogenesis 2023 Mar;176:105996
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Wei R, Su Z, Mackenzie GG
Food & function 2023 Mar 20;14(6):2684-2697
Food & function 2023 Mar 20;14(6):2684-2697
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Wang Y, Zhou H, Che Y, Wan X, Ding X, Zheng S, Wu C, Qin M, Xu Y, Yu Y, Kulyar MF, Li K, Wu Y
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Wang J, Hu D, Chen Q, Liu T, Zhou X, Xu Y, Zhou H, Gu D, Gao C
Materials today. Bio 2023 Jun;20:100679
Materials today. Bio 2023 Jun;20:100679
Open hepatic artery flow with portal vein clamping protects against bile duct injury compared to pringles maneuver.
Zhang S, Cao P, Bi P, Yang F, Wu M, Luo D, Yang B
Scandinavian journal of gastroenterology 2023 Jul;58(7):771-781
Scandinavian journal of gastroenterology 2023 Jul;58(7):771-781
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Zhang RB, Dong LC, Huang Q, Shen Y, Li HY, Yu SG, Wu QF
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Disordered gut microbiota promotes atrial fibrillation by aggravated conduction disturbance and unbalanced linoleic acid/SIRT1 signaling.
Fang C, Zuo K, Liu Z, Liu Y, Liu L, Wang Y, Yin X, Li J, Liu X, Chen M, Yang X
Biochemical pharmacology 2023 Jul;213:115599
Biochemical pharmacology 2023 Jul;213:115599
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Zhang C, Cao X, Wang H, Li Z, Zhang Y
Microvascular research 2023 Jul;148:104544
Microvascular research 2023 Jul;148:104544
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Lu S, Na K, Wei J, Tao T, Zhang L, Fang Y, Li X, Guo X
Carbohydrate polymers 2023 Jul 15;312:120806
Carbohydrate polymers 2023 Jul 15;312:120806
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Tian Z, Khan AI, Rehman AU, Deng T, Ma C, Wang L
Gut pathogens 2023 Jan 9;15(1):2
Gut pathogens 2023 Jan 9;15(1):2
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Zhang X, Shi L, Wang N, Li Q, Zhang L, Han N, Yan T, Ren D, Zhang B, Zhao Y, Yang X
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
Niu C, Hu XL, Yuan ZW, Xiao Y, Ji P, Wei YM, Hua YL
Journal of ethnopharmacology 2023 Jan 10;300:115741
Journal of ethnopharmacology 2023 Jan 10;300:115741
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Zhang X, Zhang Y, He Y, Zhu X, Ai Q, Shi Y
Journal of translational medicine 2023 Jan 10;21(1):14
Journal of translational medicine 2023 Jan 10;21(1):14
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Weng JQ, Li JB, Yuan MF, Yao TT, Zhang JF, Zeng YY, Zhao J, Li Y, Xu K, Shen XX
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Liu D, Tian Q, Liu K, Ren F, Liu G, Zhou J, Yuan L, Fang Z, Zou B, Wang S
Journal of agricultural and food chemistry 2023 Feb 8;
Journal of agricultural and food chemistry 2023 Feb 8;
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Yang Y, Ding T, Xiao G, Huang J, Luo D, Yue M, Su Y, Jiang S, Zeng J, Liu Y
Biomedicines 2023 Feb 5;11(2)
Biomedicines 2023 Feb 5;11(2)
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Zhao S, Zhang Y, Ding H, Hu S, Wu X, Ma A, Ma Y
Nutrients 2023 Feb 28;15(5)
Nutrients 2023 Feb 28;15(5)
Sodium butyrate protects against rotavirus-induced intestinal epithelial barrier damage by activating AMPK-Nrf2 signaling pathway in IPEC-J2 cells.
Dong X, Wang Y, Zhu X, Shen L, Chen L, Niu L, Gan M, Zhang S, Zhang M, Jiang J, Chen D, Zhu L, Zhao Y
International journal of biological macromolecules 2023 Feb 15;228:186-196
International journal of biological macromolecules 2023 Feb 15;228:186-196
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
Gu K, Wang F, Sun W, Liu G, Jia G, Zhao H, Chen X, Wu C, Tian G, Cai J, Zhang R, Wang J
Animal biotechnology 2023 Dec;34(8):4069-4080
Animal biotechnology 2023 Dec;34(8):4069-4080
A high-concentrate diet induces colonic inflammation and barrier damage in Hu sheep.
Chen M, Xie W, Zhou S, Ma N, Wang Y, Huang J, Shen X, Chang G
Journal of dairy science 2023 Dec;106(12):9644-9662
Journal of dairy science 2023 Dec;106(12):9644-9662
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan JN, Lorson CL, Watrelot AA, Foster JM, Mansell TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
International journal of molecular sciences 2023 Dec 30;25(1)
International journal of molecular sciences 2023 Dec 30;25(1)
Roseburia intestinalis relieves intrahepatic cholestasis of pregnancy through bile acid/FXR-FGF15 in rats.
Sun H, Su X, Liu Y, Li G, Du Q
iScience 2023 Dec 15;26(12):108392
iScience 2023 Dec 15;26(12):108392
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
Zheng X, Ma W, Wang Y, Wu C, Wang J, Ma Z, Wei Y, Cui C, Zhang S, Guan W, Chen F
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Shanmugam M, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan J, Lorson CL, Watrelot AA, Foster JM, Mansel TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
bioRxiv : the preprint server for biology 2023 Aug 24;
bioRxiv : the preprint server for biology 2023 Aug 24;
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Hu J, Ding R, Liu S, Wang J, Li J, Shang Y
iScience 2023 Aug 18;26(8):107503
iScience 2023 Aug 18;26(8):107503
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Yang X, Wang Q, Zhang X, Li L, Cao X, Zhou L, Huang Y, Sun G, Chen Y
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Blockade of neutrophil extracellular traps ameliorates toluene diisocyanate-induced steroid-resistant asthma.
Peng X, Li Y, Zhao W, Yang S, Huang J, Chen Y, Wang Y, Gong Z, Chen X, Yu C, Cai S, Zhao H
International immunopharmacology 2023 Apr;117:109719
International immunopharmacology 2023 Apr;117:109719
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)
Nutrients 2023 Apr 4;15(7)
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Wang M, Li L, Qian J, Wang N, Bao J, Lu J, Chen F, Li Y, Zhang Y, Yan F
iScience 2023 Apr 21;26(4):106346
iScience 2023 Apr 21;26(4):106346
Ginkgo biloba Extract Preventively Intervenes in Citrobacter Rodentium-Induced Colitis in Mice.
Chen T, Chen Y, Li K, Chen Z, Zhao Q, Fan Y, Liu Y, Zhang S, Hao Z
Nutrients 2023 Apr 21;15(8)
Nutrients 2023 Apr 21;15(8)
The Uterine Melatonergic Systems of AANAT and Melatonin Membrane Receptor 2 (MT2) Are Essential for Endometrial Receptivity and Early Implantation in Mice.
Ma X, Wang J, Wang L, Yan L, Liu Y, Ma W, Ji P, Zhang L, Liu G
International journal of molecular sciences 2023 Apr 12;24(8)
International journal of molecular sciences 2023 Apr 12;24(8)
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Li P, Li M, Song Y, Huang X, Wu T, Xu ZZ, Lu H
Frontiers in nutrition 2022;9:832848
Frontiers in nutrition 2022;9:832848
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Zhou Q, Shen B, Huang R, Liu H, Zhang W, Song M, Liu K, Lin X, Chen S, Liu Y, Wang Y, Zhi F
Frontiers in nutrition 2022;9:1063699
Frontiers in nutrition 2022;9:1063699
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Peng H, Jin L, Zhang Q, Shen Y, Wang Z, Zhou F, Yu Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling.
Huang D, Wang P, Chen J, Li Y, Zhu M, Tang Y, Zhou W
Frontiers in immunology 2022;13:995791
Frontiers in immunology 2022;13:995791
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Wang K, Chen D, Yu B, He J, Mao X, Huang Z, Yan H, Wu A, Luo Y, Zheng P, Yu J, Luo J
Frontiers in immunology 2022;13:921613
Frontiers in immunology 2022;13:921613
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Kim IH, Zhang R, Wang J
Frontiers in microbiology 2022;13:919431
Frontiers in microbiology 2022;13:919431
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
Wang Z, You L, Ren Y, Zhu X, Mao X, Liang X, Wang T, Guo Y, Liu T, Xue J
Frontiers in physiology 2022;13:900961
Frontiers in physiology 2022;13:900961
3,4-Methylenedioxy-β-Nitrostyrene Alleviates Dextran Sulfate Sodium-Induced Mouse Colitis by Inhibiting the NLRP3 Inflammasome.
Zheng J, Jiang Z, Song Y, Huang S, Du Y, Yang X, Xiao Y, Ma Z, Xu D, Li J
Frontiers in pharmacology 2022;13:866228
Frontiers in pharmacology 2022;13:866228
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Porphyromonas gingivalis secretion leads to dysplasia of normal esophageal epithelial cells via the Sonic hedgehog pathway.
Jia X, Liu J, He Y, Huang X
Frontiers in cellular and infection microbiology 2022;12:982636
Frontiers in cellular and infection microbiology 2022;12:982636
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Yu C, Liu S, Niu Y, Fu L
The Journal of nutritional biochemistry 2022 Sep;107:109059
The Journal of nutritional biochemistry 2022 Sep;107:109059
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Zhang K, Xu Y, Yang Y, Guo M, Zhang T, Zong B, Huang S, Suo L, Ma B, Wang X, Wu Y, Brugger D, Chen Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.
Xu RC, Miao WT, Xu JY, Xu WX, Liu MR, Ding ST, Jian YX, Lei YH, Yan N, Liu HD
Nutrients 2022 Oct 7;14(19)
Nutrients 2022 Oct 7;14(19)
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Qi S, Luo R, Han X, Nie W, Ye N, Fu C, Gao F
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer.
Zhu L, Chen Y, Du H, Cong Y, Yan W, Ma K, Huang X
Biochemical and biophysical research communications 2022 Nov 12;629:121-127
Biochemical and biophysical research communications 2022 Nov 12;629:121-127
Cadherin-16 inhibits thyroid carcinoma cell proliferation and invasion.
Yang X, Li Y, Liu G, Zha W, Liu Y
Oncology letters 2022 May;23(5):145
Oncology letters 2022 May;23(5):145
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
Zhang K, Lian S, Shen X, Zhao X, Zhao W, Li C
International journal of biological macromolecules 2022 May 31;208:890-900
International journal of biological macromolecules 2022 May 31;208:890-900
Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.
Shi P, Zhao T, Wang W, Peng F, Wang T, Jia Y, Zou L, Wang P, Yang S, Fan Y, Zong J, Qu X, Wang S
Nutrition & metabolism 2022 May 18;19(1):36
Nutrition & metabolism 2022 May 18;19(1):36
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Li J, Li Y, Liu P, Wang X, Ma Y, Zhong Q, Yang Q
Journal of virology 2022 May 11;96(9):e0038022
Journal of virology 2022 May 11;96(9):e0038022
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Zhang M, Yang L, Zhu M, Yang B, Yang Y, Jia X, Feng L
International journal of biological macromolecules 2022 May 1;206:849-860
International journal of biological macromolecules 2022 May 1;206:849-860
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Hu R, Wu S, Li B, Tan J, Yan J, Wang Y, Tang Z, Liu M, Fu C, Zhang H, He J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Du L, Hao YM, Yang YH, Zheng Y, Wu ZJ, Zhou MQ, Wang BZ, Wang YM, Wu H, Su GH
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Spinal anesthesia alleviates dextran sodium sulfate-induced colitis by modulating the gut microbiota.
Hong Y, Zhao J, Chen YR, Huang ZH, Hou LD, Shen B, Xin Y
World journal of gastroenterology 2022 Mar 28;28(12):1239-1256
World journal of gastroenterology 2022 Mar 28;28(12):1239-1256
Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells.
Jia Z, Wang K, Duan Y, Hu K, Zhang Y, Wang M, Xiao K, Liu S, Pan Z, Ding X
Cell death discovery 2022 Mar 18;8(1):122
Cell death discovery 2022 Mar 18;8(1):122
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
Liu A, Chen X, Huang Z, Chen D, Yu B, Chen H, He J, Yan H, Zheng P, Yu J, Luo Y
Animal biotechnology 2022 Jun;33(3):563-570
Animal biotechnology 2022 Jun;33(3):563-570
Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.
Yu Y, Bian Y, Shi JX, Gu Y, Yuan DP, Yu B, Shi L, Dou DH
Bioengineered 2022 Jun;13(6):14616-14631
Bioengineered 2022 Jun;13(6):14616-14631
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Tian S, Wang J, Gao R, Wang J, Zhu W
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Ding Q, Cao F, Lai S, Zhuge H, Chang K, Valencak TG, Liu J, Li S, Ren D
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Polysaccharides from Lachnum sp. Inhibited colitis-associated colon tumorigenesis in mice by modulating fecal microbiota and metabolites.
Zong S, Ye H, Ye Z, He Y, Zhang X, Ye M
International immunopharmacology 2022 Jul;108:108656
International immunopharmacology 2022 Jul;108:108656
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Ru M, Wang W, Zhai Z, Wang R, Li Y, Liang J, Kothari D, Niu K, Wu X
Food & function 2022 Jul 18;13(14):7507-7519
Food & function 2022 Jul 18;13(14):7507-7519
The miR-199a-5p/PD-L1 axis regulates cell proliferation, migration and invasion in follicular thyroid carcinoma.
Lin J, Qiu Y, Zheng X, Dai Y, Xu T
BMC cancer 2022 Jul 11;22(1):756
BMC cancer 2022 Jul 11;22(1):756
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
Wang Y, Ha M, Li M, Zhang L, Chen Y
Human cell 2022 Jan;35(1):271-285
Human cell 2022 Jan;35(1):271-285
Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier.
Ge L, Qi J, Shao B, Ruan Z, Ren Y, Sui S, Wu X, Sun X, Liu S, Li S, Xu C, Song W
Gut microbes 2022 Jan-Dec;14(1):2013764
Gut microbes 2022 Jan-Dec;14(1):2013764
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
He Y, Liu Y, Tang J, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Kai L, Zong X, Jiang Q, Lu Z, Wang F, Wang Y, Wang T, Jin M
International journal of biological macromolecules 2022 Jan 15;195:142-151
International journal of biological macromolecules 2022 Jan 15;195:142-151
Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis.
Yang Y, Chen Y, Zhao Y, Ji F, Zhang L, Tang S, Zhang S, Hu Q, Li Z, Zhang F, Li Q, Li L
Stem cell research & therapy 2022 Feb 5;13(1):57
Stem cell research & therapy 2022 Feb 5;13(1):57
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Wang Q, Wang C, Abdullah, Tian W, Qiu Z, Song M, Cao Y, Xiao J
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Highly Pathogenic PRRSV-Infected Alveolar Macrophages Impair the Function of Pulmonary Microvascular Endothelial Cells.
Sun W, Wu W, Jiang N, Ge X, Zhang Y, Han J, Guo X, Zhou L, Yang H
Viruses 2022 Feb 22;14(3)
Viruses 2022 Feb 22;14(3)
Dietary ellagic acid supplementation attenuates intestinal damage and oxidative stress by regulating gut microbiota in weanling piglets.
Qin W, Xu B, Chen Y, Yang W, Xu Y, Huang J, Duo T, Mao Y, Zhou G, Yan X, Ma L
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:322-333
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Dec;11:322-333
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Xia X, Lin H, Luo F, Wu X, Zhu L, Chen S, Luo H, Ye F, Peng X, Zhang Y, Yang G, Lin Q
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Wang W, Jiang S, Xu C, Tang L, Liang Y, Zhao Y, Zhu G
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Daidzein Protects Caco-2 Cells against Lipopolysaccharide-Induced Intestinal Epithelial Barrier Injury by Suppressing PI3K/AKT and P38 Pathways.
Zhang B, Wei X, Ding M, Luo Z, Tan X, Zheng Z
Molecules (Basel, Switzerland) 2022 Dec 15;27(24)
Molecules (Basel, Switzerland) 2022 Dec 15;27(24)
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Na K, Wei J, Zhang L, Fang Y, Li X, Lu S, Guo X
Carbohydrate polymers 2022 Dec 1;297:120043
Carbohydrate polymers 2022 Dec 1;297:120043
Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.
Meng Y, Wang Q, Ma Z, Li W, Niu K, Zhu T, Lin H, Lu C, Fan H
PLoS pathogens 2022 Aug;18(8):e1010765
PLoS pathogens 2022 Aug;18(8):e1010765
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Liu Z, Jiang Z, Zhang Z, Liu T, Fan Y, Liu T, Peng N
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Deoxynivalenol damages the intestinal barrier and biota of the broiler chickens.
Wan S, Sun N, Li H, Khan A, Zheng X, Sun Y, Fan R
BMC veterinary research 2022 Aug 15;18(1):311
BMC veterinary research 2022 Aug 15;18(1):311
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Li HL, Wei YY, Li XH, Zhang SS, Zhang RT, Li JH, Ma BW, Shao SB, Lv ZW, Ruan H, Zhou HG, Yang C
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420
Food & function 2022 Apr 20;13(8):4399-4420
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Wang D, Zhou L, Zhou H, Hou G
Frontiers in veterinary science 2021;8:656179
Frontiers in veterinary science 2021;8:656179
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Zou W, Qian C, Zhang S, Wan X, Wei Z, Li X, Wu Y, Chen W, Wang A, Zhao Y, Lu Y
Oxidative medicine and cellular longevity 2021;2021:7037786
Oxidative medicine and cellular longevity 2021;2021:7037786
Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets.
Xu B, Qin W, Xu Y, Yang W, Chen Y, Huang J, Zhao J, Ma L
Oxidative medicine and cellular longevity 2021;2021:6221012
Oxidative medicine and cellular longevity 2021;2021:6221012
Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB.
Chu BX, Li YN, Liu N, Yuan LX, Chen SY, Zhu YH, Wang JF
Frontiers in immunology 2021;12:757909
Frontiers in immunology 2021;12:757909
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Xu Y, Xie L, Tang J, He X, Zhang Z, Chen Y, Zhou J, Gan B, Peng W
Frontiers in microbiology 2021;12:742033
Frontiers in microbiology 2021;12:742033
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
Qu Y, Li X, Xu F, Zhao S, Wu X, Wang Y, Xie J
Frontiers in immunology 2021;12:679897
Frontiers in immunology 2021;12:679897
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Tang XH, Melis M, Mai K, Gudas LJ, Trasino SE
Frontiers in pharmacology 2021;12:630557
Frontiers in pharmacology 2021;12:630557
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
Melatonin as Immune Potentiator for Enhancing Subunit Vaccine Efficacy against Bovine Viral Diarrhea Virus.
Wang YX, Yang GH, Zhang LL, Wang J, Wang JF
Vaccines 2021 Sep 18;9(9)
Vaccines 2021 Sep 18;9(9)
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong G, Zhang J, Guo Y, Wang Y, Wu M, Ren J, Li Y, Zhang X, Zhou B, Zhao W, Lou Y, Wang H, Ye J
International immunopharmacology 2021 Oct;99:107980
International immunopharmacology 2021 Oct;99:107980
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Hou G, Zhang M, Wang J, Zhu W
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Li L, Zhou C, Li T, Xiao W, Yu M, Yang H
Annals of translational medicine 2021 Mar;9(5):365
Annals of translational medicine 2021 Mar;9(5):365
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Fang W, Zhao P, Shen A, Liu L, Chen H, Chen Y, Peng J, Sferra TJ, Sankararaman S, Luo Y, Ke X
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells.
Levine F, Ogunwobi OO
Cancers 2021 Mar 2;13(5)
Cancers 2021 Mar 2;13(5)
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Damage to intestinal barrier integrity in piglets caused by porcine reproductive and respiratory syndrome virus infection.
Zhao J, Wan S, Sun N, Sun P, Sun Y, Khan A, Guo J, Zheng X, Fan K, Yin W, Li H
Veterinary research 2021 Jun 23;52(1):93
Veterinary research 2021 Jun 23;52(1):93
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
Liu Y, Li L, Pan N, Gu J, Qiu Z, Cao G, Dou Y, Dong L, Shuai J, Sang A
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Zong X, Cheng Y, Xiao X, Fu J, Wang F, Lu Z, Wang Y, Jin M
International journal of biological macromolecules 2021 Jul 31;183:861-869
International journal of biological macromolecules 2021 Jul 31;183:861-869
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Huang X, Pan M, Du P, Chen Y, Zhang C, Lu W, Lin J
Annals of translational medicine 2021 Jan;9(2):122
Annals of translational medicine 2021 Jan;9(2):122
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.
Shi Y, Zou Y, Xiong Y, Zhang S, Song M, An X, Liu C, Zhang W, Chen S
Gut microbes 2021 Jan-Dec;13(1):1946369
Gut microbes 2021 Jan-Dec;13(1):1946369
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Lactobacillus plantarum KLDS1.0344 and Lactobacillus acidophilus KLDS1.0901 Mixture Prevents Chronic Alcoholic Liver Injury in Mice by Protecting the Intestinal Barrier and Regulating Gut Microbiota and Liver-Related Pathways.
Li H, Shi J, Zhao L, Guan J, Liu F, Huo G, Li B
Journal of agricultural and food chemistry 2021 Jan 13;69(1):183-197
Journal of agricultural and food chemistry 2021 Jan 13;69(1):183-197
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Yang L, Zhang Q, Huang J, Liu D, Lan Y, Yuan L, Chen Q
Journal of ethnopharmacology 2021 Jan 10;264:113377
Journal of ethnopharmacology 2021 Jan 10;264:113377
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
Intraperitoneal supplementation of iron alleviates dextran sodium sulfate-induced colitis by enhancing intestinal barrier function.
Liang L, Xiong Q, Kong J, Tian C, Miao L, Zhang X, Du H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112253
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112253
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Xie X, Zhou J, Hu L, Shu R, Zhang M, Xiong Z, Wu F, Fu Z
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Immunization with recombinant E(rns)-LTB fusion protein elicits protective immune responses against bovine viral diarrhea virus.
Wang SH, Yang GH, Nie JW, Wang J, Wang YX, Du MZ, Guo L, Yang RJ, Zhu YH
Veterinary microbiology 2021 Aug;259:109084
Veterinary microbiology 2021 Aug;259:109084
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Wang X, Yang Y, Yang X, Liu X, Wang X, Gao L, Yang C, Lan R, Bi J, Zhao Q, Yang G, Wang J, Lin Y, Liu J, Yin G
Microbial pathogenesis 2021 Aug;157:105012
Microbial pathogenesis 2021 Aug;157:105012
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Bai X, Fu R, Duan Z, Wang P, Zhu C, Fan D
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells.
Jin Y, Zhai Z, Jia H, Lai J, Si X, Wu Z
Food & function 2021 Aug 2;12(15):6889-6899
Food & function 2021 Aug 2;12(15):6889-6899
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Gao R, Tian S, Wang J, Zhu W
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
Ogino T, Matsunaga N, Tanaka T, Tanihara T, Terajima H, Yoshitane H, Fukada Y, Tsuruta A, Koyanagi S, Ohdo S
eLife 2021 Apr 23;10
eLife 2021 Apr 23;10
Dietary glycyl-glutamine supplementation ameliorates intestinal integrity, inflammatory response, and oxidative status in association with the gut microbiota in LPS-challenged piglets.
Xu B, Yan Y, Yin B, Zhang L, Qin W, Niu Y, Tang Y, Zhou S, Yan X, Ma L
Food & function 2021 Apr 21;12(8):3539-3551
Food & function 2021 Apr 21;12(8):3539-3551
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Shi Y, Gao F, Yang X, Liu D, Han Q, Liu Z, Zhu H, Shen Y
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Wen C, Guo Q, Wang W, Duan Y, Zhang L, Li J, He S, Chen W, Li F
Frontiers in physiology 2020;11:449
Frontiers in physiology 2020;11:449
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
Qiao CM, Sun MF, Jia XB, Li Y, Zhang BP, Zhao LP, Shi Y, Zhou ZL, Zhu YL, Cui C, Shen YQ
Neurochemical research 2020 Sep;45(9):2128-2142
Neurochemical research 2020 Sep;45(9):2128-2142
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth.
Leng L, Ma J, Lv L, Wang W, Gao D, Zhu Y, Wu Z
Stem cell research & therapy 2020 Sep 23;11(1):415
Stem cell research & therapy 2020 Sep 23;11(1):415
Caveolin-1 protects against DSS-induced colitis through inhibiting intestinal nitrosative stress and mucosal barrier damage in mice.
Song Y, Xie F, Ma S, Deng G, Li Y, Nie Y, Wang F, Yu G, Gao Z, Chen K, Han L, Gao L
Biochemical pharmacology 2020 Oct;180:114153
Biochemical pharmacology 2020 Oct;180:114153
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Xiao Q, Shu R, Wu C, Tong Y, Xiong Z, Zhou J, Yu C, Xie X, Fu Z
Journal of affective disorders 2020 Nov 1;276:476-486
Journal of affective disorders 2020 Nov 1;276:476-486
Targeting claudin-4 enhances chemosensitivity in breast cancer.
Luo Y, Kishi S, Sasaki T, Ohmori H, Fujiwara-Tani R, Mori S, Goto K, Nishiguchi Y, Mori T, Kawahara I, Kondoh M, Kuniyasu H
Cancer science 2020 May;111(5):1840-1850
Cancer science 2020 May;111(5):1840-1850
O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.
Bagdonaite I, Pallesen EM, Ye Z, Vakhrushev SY, Marinova IN, Nielsen MI, Kramer SH, Pedersen SF, Joshi HJ, Bennett EP, Dabelsteen S, Wandall HH
EMBO reports 2020 Jun 4;21(6):e48885
EMBO reports 2020 Jun 4;21(6):e48885
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Gao J, Li X, Gao L, Chen H, Baras BH, Liu X, Liu H, Rana A, Gao M, Ruan J
International journal of molecular medicine 2020 Jul;46(1):179-190
International journal of molecular medicine 2020 Jul;46(1):179-190
Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor.
Bi J, Zhang J, Ren Y, Du Z, Li T, Wang T, Zhang L, Wang M, Wu Z, Lv Y, Wu R
Journal of cellular and molecular medicine 2020 Jan;24(1):996-1009
Journal of cellular and molecular medicine 2020 Jan;24(1):996-1009
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Exposure to dibutyl phthalate impairs lipid metabolism and causes inflammation via disturbing microbiota-related gut-liver axis.
Xiong Z, Zeng Y, Zhou J, Shu R, Xie X, Fu Z
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1382-1393
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1382-1393
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Li P, Wu M, Xiong W, Li J, An Y, Ren J, Xie Y, Xue H, Yan D, Li M, Zhong G
International immunopharmacology 2020 Apr;81:106288
International immunopharmacology 2020 Apr;81:106288
Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier.
Hui L, Nie Y, Li S, Guo M, Yang W, Huang R, Chen J, Liu Y, Lu X, Chen Z, Yang Q, Wu Y
PLoS pathogens 2020 Apr;16(4):e1008509
PLoS pathogens 2020 Apr;16(4):e1008509
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cheng Y, Wu T, Tang S, Liang F, Fang Y, Cao W, Pan S, Xu X
Food & function 2020 Apr 1;11(4):3167-3179
Food & function 2020 Apr 1;11(4):3167-3179
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
He Y, Li X, Yu H, Ge Y, Liu Y, Qin X, Jiang M, Wang X
Frontiers in cellular and infection microbiology 2019;9:393
Frontiers in cellular and infection microbiology 2019;9:393
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Tang J, Cao L, Jia G, Liu G, Chen X, Tian G, Cai J, Shang H, Zhao H
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
Hong W, Guo F, Yang M, Xu D, Zhuang Z, Niu B, Bai Q, Li X
Lipids in health and disease 2019 Nov 22;18(1):203
Lipids in health and disease 2019 Nov 22;18(1):203
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
The chromatin remodeling protein BRM regulates the transcription of tight junction proteins: Implication in breast cancer metastasis.
Yang Y, Liu L, Fang M, Bai H, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 May;1862(5):547-556
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 May;1862(5):547-556
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
He Y, Yu H, Ge Y, Li X, Jiang M, Liu Y, Li X, Wang Y, Guo M, Qin X, Wang X
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Oral Administration of a Select Mixture of Lactobacillus and Bacillus Alleviates Inflammation and Maintains Mucosal Barrier Integrity in the Ileum of Pigs Challenged with Salmonella Infantis.
Liu X, Xia B, He T, Li D, Su JH, Guo L, Wang JF, Zhu YH
Microorganisms 2019 May 15;7(5)
Microorganisms 2019 May 15;7(5)
Modulating the gut microbiota and inflammation is involved in the effect of Bupleurum polysaccharides against diabetic nephropathy in mice.
Feng Y, Weng H, Ling L, Zeng T, Zhang Y, Chen D, Li H
International journal of biological macromolecules 2019 Jul 1;132:1001-1011
International journal of biological macromolecules 2019 Jul 1;132:1001-1011
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Wu M, Li P, An Y, Ren J, Yan D, Cui J, Li D, Li M, Wang M, Zhong G
Pharmacological research 2019 Dec;150:104489
Pharmacological research 2019 Dec;150:104489
Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers.
Mukaiyama M, Yamasaki Y, Usui T, Nagumo Y
FEBS letters 2019 Aug;593(16):2250-2260
FEBS letters 2019 Aug;593(16):2250-2260
All‑trans retinoic acid alters the expression of the tight junction proteins Claudin‑1 and ‑4 and epidermal barrier function‑associated genes in the epidermis.
Li J, Li Q, Geng S
International journal of molecular medicine 2019 Apr;43(4):1789-1805
International journal of molecular medicine 2019 Apr;43(4):1789-1805
The Choroid Plexus Functions as a Niche for T-Cell Stimulation Within the Central Nervous System.
Strominger I, Elyahu Y, Berner O, Reckhow J, Mittal K, Nemirovsky A, Monsonego A
Frontiers in immunology 2018;9:1066
Frontiers in immunology 2018;9:1066
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway.
Jia Y, Xiao Z, Gongsun X, Xin Z, Shang B, Chen G, Wang Z, Jiang W
OncoTargets and therapy 2018;11:4221-4232
OncoTargets and therapy 2018;11:4221-4232
Natural killer T cell ligand alpha-galactosylceramide protects against gut ischemia reperfusion-induced organ injury in mice.
Zhang J, Bi J, Ren Y, Du Z, Li T, Li Q, Ke M, Dong J, Lv Y, Wu R
Cytokine 2018 Nov;111:237-245
Cytokine 2018 Nov;111:237-245
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
Dong Y, Wang Z, Qin Z, Cao J, Chen Y
Journal of molecular histology 2018 Feb;49(1):85-97
Journal of molecular histology 2018 Feb;49(1):85-97
TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin.
Kanda Y, Yamasaki Y, Sasaki-Yamaguchi Y, Ida-Koga N, Kamisuki S, Sugawara F, Nagumo Y, Usui T
Scientific reports 2018 Feb 2;8(1):2251
Scientific reports 2018 Feb 2;8(1):2251
Blocking FGFR4 exerts distinct anti-tumorigenic effects in esophageal squamous cell carcinoma.
Xin Z, Song X, Jiang B, Gongsun X, Song L, Qin Q, Wang Q, Shi M, Liu X
Thoracic cancer 2018 Dec;9(12):1687-1698
Thoracic cancer 2018 Dec;9(12):1687-1698
KCTD11 inhibits growth and metastasis of hepatocellular carcinoma through activating Hippo signaling.
Tong R, Yang B, Xiao H, Peng C, Hu W, Weng X, Cheng S, Du C, Lv Z, Ding C, Zhou L, Xie H, Wu J, Zheng S
Oncotarget 2017 Jun 6;8(23):37717-37729
Oncotarget 2017 Jun 6;8(23):37717-37729
(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.
Zhang X, Xu F, Liu L, Feng L, Wu X, Shen Y, Sun Y, Wu X, Xu Q
International immunopharmacology 2017 Dec;53:1-10
International immunopharmacology 2017 Dec;53:1-10
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G
Journal of virology 2016 Nov 1;90(21):9632-9643
Journal of virology 2016 Nov 1;90(21):9632-9643
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Han J, Xu Y, Yang D, Yu N, Bai Z, Bian L
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.
Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T
PLoS pathogens 2013;9(8):e1003589
PLoS pathogens 2013;9(8):e1003589
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 13050-1-AP(CLDN1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Claudin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Claudin 1. This antibody recognizes human, mouse antigen. The Claudin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
