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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Flow cytometry [1]
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- Product number
- MAB4618 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal Claudin-1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Stains human Claudin-1 transfectants but not irrelevant transfectants.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy.
BAFF and APRIL expression as an autoimmune signature of membranous nephropathy.
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.
Hepatitis C virus induces CD81 and claudin-1 endocytosis.
Hong SP, Chan TE, Lombardo Y, Corleone G, Rotmensz N, Bravaccini S, Rocca A, Pruneri G, McEwen KR, Coombes RC, Barozzi I, Magnani L
Nature communications 2019 Sep 2;10(1):3840
Nature communications 2019 Sep 2;10(1):3840
BAFF and APRIL expression as an autoimmune signature of membranous nephropathy.
Han SS, Yang SH, Jo HA, Oh YJ, Park M, Kim JY, Lee H, Lee JP, Lee SH, Joo KW, Lim CS, Kim YS, Kim DK
Oncotarget 2018 Jan 9;9(3):3292-3302
Oncotarget 2018 Jan 9;9(3):3292-3302
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.
Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong FHT, Calabrese D, Leboeuf C, Fofana I, Thumann C, Bandiera S, Lütgehetmann M, Volz T, Davis C, Harris HJ, Mee CJ, Girardi E, Chane-Woon-Ming B, Ericsson M, Fletcher N, Bartenschlager R, Pessaux P, Vercauteren K, Meuleman P, Villa P, Kaderali L, Pfeffer S, Heim MH, Neunlist M, Zeisel MB, Dandri M, McKeating JA, Robinet E, Baumert TF
Nature biotechnology 2015 May;33(5):549-554
Nature biotechnology 2015 May;33(5):549-554
Hepatitis C virus induces CD81 and claudin-1 endocytosis.
Farquhar MJ, Hu K, Harris HJ, Davis C, Brimacombe CL, Fletcher SJ, Baumert TF, Rappoport JZ, Balfe P, McKeating JA
Journal of virology 2012 Apr;86(8):4305-16
Journal of virology 2012 Apr;86(8):4305-16
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Claudin-1 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Rat Anti-Human Claudin-1 Monoclonal Antibody (Catalog # MAB4618, filled histogram) or isotype control antibody (Catalog # MAB006, open histogram), followed by Allophycocyanin-conjugated Anti-Rat IgG F(ab')2 Secondary Antibody (Catalog # F0113).
